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1. Efficacy of a diarylheptanoid derivative against Leishmania amazonensis
by Alves, Luciana Vignólio and Temporal, Rosane Maria and Cysne-Finkelstein, Léa and Leon, Leonor Laura
Efficacy of a diarylheptanoid derivative against Leishmania amazonensis, 12/2003
The activity of several diarylheptanoid derivatives (curcuminoids) was previously evaluated against Leishmania amazonensis   promastigotes and among them the... 
diarylheptanoid - treatment trial - Leishmania amazonensis   - leishmaniasis
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2. Action of Pentoxifylline on Experimental Cutaneous Leishmaniasis Due to Leishmania (Leishmania) amazonensis
by Oliveira, Thiago de Sá and Neto, Mário Capp and Martins, Bernardo José Alves and Rodrigues, Helbert Abe and Antonino, Rosa Maria Parreiras and Magalhães, Albino Verçosa
Action of Pentoxifylline on Experimental Cutaneous Leishmaniasis Due to Leishmania (Leishmania) amazonensis, 12/2000
In the animal model of leishmaniasis caused by Leishmania (Leishmania) amazonensis there is a complex mechanism of the host-parasite interaction. The present... 
pentoxifylline, Leishmania (Leishmania) amazonensis, tumour necrosis factor-alpha
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3. A dhfr-ts- Leishmania major Knockout Mutant Cross-protects against Leishmania amazonensis
by Veras, P. S. T and Brodskyn, C. I and Balestieri, F. M. P and de Freitas, L. A. R and Ramos, A. P. S and Queiroz, A. R. P and Barral, A and Beverley, S. M and Barral-Netto, Manoel
A dhfr-ts- Leishmania major Knockout Mutant Cross-protects against Leishmania amazonensis, 12/1999
E10-5A3 is a dhfr-ts- Leishmania major double knockout auxotrophic shown previously to induce substantial protection against virulent L. major infection in... 
auxotrophic Leishmania major - Leishmania amazonensis - immunization - cross-protection
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4. Cyclic 3'-5' guanosine monophosphate-dependent activity in Leishmania amazonensis
by Géigel, L. F and Leon, L. L
Cyclic 3'-5' guanosine monophosphate-dependent activity in Leishmania amazonensis, 12/2003
Although there are some data concerning the nitric oxide and the cyclic 3'-5'guanosine monophosphate (cGMP) signaling pathway in trypanosomatids, there is no... 
Leishmania amazonensis   - cyclic 3'-5'-guanosine monophosphate - metacyclogenesis
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5. Immune and inflammatory responses to Leishmania amazonensis isolated from different clinical forms of human leishmaniasis in CBA mice
by de Souza, Valderes L and Veras, Patrícia S.T and Welby-Borges, Marcus and Silva, Tânia M.C and Leite, Bruna R and Ferraro, Rodrigo B and Meyer-Fernandes, José R and Barral, Aldina and Costa, Jackson Mauricio Lopes and de Freitas, Luiz A.R
04/2011
Leishmania amazonensis causes different diseases depending on the host and parasitic virulence factors. In this study, CBA mice were infected with L.... 
Leishmania amazonensis - inflammatory responses - enzymatic activity
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6. Low and high-dose intradermal infection with Leishmania major and Leishmania amazonensis in C57BL/6 mice
by Côrtes, Denise Fonseca and Carneiro, Matheus Batista Heitor and Santos, Liliane Martins and de Oliveira Souza, Talita Correia and Maioli, Tatiane Uceli and Duz, Ana Luiza C and Ramos-Jorge, Maria Letícia and Afonso, Luis Carlos Crocco and Carneiro, Claudia and Vieira, Leda Quercia
01/2011
A model of skin infection with Leishmania amazonensis with low doses of parasites is compared to infection with high doses of L. amazonensis and low and high... 
Leishmania - L. amazonensis - L. major - infection - cytokines
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7. Kinetoplastid membrane protein-11 is present in promastigotes and amastigotes of Leishmania amazonensis and its surface expression increases during metacyclogenesis
by Matos, Denise C.S and Faccioli, Lanuza A.P and Cysne-Finkelstein, Léa and De Luca, Paula Mello and Corte-Real, Suzana and Armôa, Geraldo R.G and Lemes, Elezer Monte Blanco and Decote-Ricardo, Débora and Mendonça, Sergio C.F
06/2010
Kinetoplastid membrane protein-11 (KMP-11), a protein present in all kinetoplastid protozoa, is considered a potential candidate for a leishmaniasis vaccine. A... 
metacyclogenesis | KMP-11 | expression | promastigote | amastigote | Leishmania amazonensis
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8. Full Text Leishmania DNA is rapidly degraded following parasite death: an analysis by microscopy and real-time PCR
by Prina, Eric and Roux, Emeric and Mattei, Denise and Milon, Geneviève
Microbes and Infection, ISSN 1286-4579, 2007, Volume 9, Issue 11, pp. 1307 - 1315
Control of human leishmaniases relies on appropriate diagnosis and reliable methods for monitoring chemotherapy. The current method used for estimation of... 
Persistence | DNA | Drug treatment | MeSH ®: Leishmania amazonensis | Mice | Real-time PCR, Microscopy | Macrophages | SYBR Green I | MeSH | Leishmania amazonensis | DIAGNOSIS | SYBR green I | SENSITIVITY | MICROBIOLOGY | real-time PCR | IMMUNOLOGY | mice | drug treatment | macrophages | POLYMERASE-CHAIN-REACTION | VIROLOGY | persistence | AMAZONENSIS | microscopy | KALA-AZAR | MeSH (R) | VISCERAL LEISHMANIASIS | ISOLATED AMASTIGOTES | BLOOD | Macrophages - chemistry | Leucine - pharmacology | Antipruritics - pharmacology | Leishmania - cytology | Macrophages - parasitology | Animals | Microscopy | DNA, Protozoan - metabolism | Cell Death | Polymerase Chain Reaction | Female | Leishmania - genetics | Life Sciences | Microbiology and Parasitology | Parasitology | Real-time PCR
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9. Antileishmanial activity of lapachol analogues
by Lima, Nadja M. F and Correia, Clariane S and Leon, Leonor L and Machado, Gérzia M. C and Madeira, Maria de Fátima and Santana, Antônio Euzébio G and Goulart, Marília O. F
Antileishmanial activity of lapachol analogues, 11/2004
The antileishmanial activity of lapachol, isolapachol, and dihydrolapachol, along with soluble derivatives (potassium salt) and acetate was obtained. All the... 
Tropical Diseases | Microbiology | Leishmania amazonensis - Leishmania braziliensis - lapachol - isolapachol - antileishmanial activity - naphthoquinones oc04153
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10. Molecular Modeling Approaches for Determining Gene Function: Application to a Putative Poly-A Binding Protein from Leishmania amazonensis   (LaPABP)
by Silva-Jr, F. P and Veyl, F. Z and Clos, J and Simone, S. Giovanni De
Molecular Modeling Approaches for Determining Gene Function: Application to a Putative Poly-A Binding Protein from Leishmania amazonensis   (LaPABP), 12/2002
The great expansion in the number of genome sequencing projects has revealed the importance of computational methods to speed up the characterization of... 
molecular modeling - poly-A binding protein - Leishmania amazonensis   - LaPABP - bioinformatics
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11. Further observations on clinical, histopathological, and immunological features of borderline disseminated cutaneous leishmaniasis caused by Leishmania (Leishmania) amazonensis
by Silveira, Fernando T and Lainson, Ralph and Corbett, Carlos E. P
Further observations on clinical, histopathological, and immunological features of borderline disseminated cutaneous leishmaniasis caused by Leishmania (Leishmania) amazonensis, 12/2005
Leishmania (Leishmania) amazonensis has for some time been considered as the causative agent of two distinct forms of American cutaneous leishmaniasis (ACL):... 
borderline disseminated cutaneous leishmaniasis - Leishmania (Leishmania) amazonensis - histopathology - clinical manifestations - Brazil
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12. Anti-leishmanial activity of alkaloidal extract from Aspidosperma ramiflorum
by Ferreira, Izabel Cristina Piloto and Lonardoni, Maria Valdrinez Campana and Machado, Gerzia M. C and Leon, Leonor L and Filho, Lucílio Gobbi and Pinto, Luís Henrique Bissoli and Braz de Oliveira, Arildo José
Anti-leishmanial activity of alkaloidal extract from Aspidosperma ramiflorum, 12/2004
Infections due to protozoa of the genus Leishmania are a major worldwide health problem, with high endemicity in developing countries. The drugs of choice for... 
Apocynaceae - anti-leishmanial activity - Brazilian trees - monoterpenoid indolic alkaloids - Aspidosperma ramiflorum - Leishmania amazonensis - Leishmania braziliensis
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13. Leishmania (Viannia) braziliensis growth in vitro culture relies more on folic acid availability than Leihsmania (Leishmania) amazonensis
by Niño, Andrea and Camacho, Marcela
Leishmania (Viannia) braziliensis growth in vitro culture relies more on folic acid availability than Leihsmania (Leishmania) amazonensis, 12/2005
We compared the in vitro growth of promastigotes from two Leishmania species in TC-100 and Schneider media. Leihsmania (Leishmania) amazonensis replication... 
Leishmania (Viannia) braziliensis Leishmania (Leishmania) amazonensis -replication rates - in vitro culture
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14. Cell Populations in Lesions of Cutaneous Leishmaniasis of Leishmania (L.) amazonensis- infected Rhesus Macaques, Macaca mulatta
by Amaral, V. F and Pirmez, C and Gonçalves, A. J. S and Ferreira, V and Grimaldi Jr, Gabriel
Cell Populations in Lesions of Cutaneous Leishmaniasis of Leishmania (L.) amazonensis- infected Rhesus Macaques, Macaca mulatta, 12/2000
The cellular nature of the infiltrate in cutaneous lesion of rhesus monkeys experimentally infected with Leishmania (L.) amazonensis was characterized by... 
Leishmania (L.) amazonensis - Macaca mulatta - experimental leishmaniasis - systemic and local cellular immunity
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15. Further observations on clinical, histopathological, and immunological features of borderline disseminated cutaneous leishmaniasis caused by Leishmania (Leishmania) amazonensis
by Silveira, Fernando T and Lainson, Ralph and Corbett, Carlos E. P
Further observations on clinical, histopathological, and immunological features of borderline disseminated cutaneous leishmaniasis caused by Leishmania (Leishmania) amazonensis, 12/2005
Leishmania (Leishmania) amazonensis   has for some time been considered as the causative agent of two distinct forms of American cutaneous leishmaniasis (ACL):... 
borderline disseminated cutaneous leishmaniasis - Leishmania (Leishmania) amazonensis - histopathology - clinical manifestations - Brazil
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16. RESEARCH NOTE - Putative Reservoirs of Leishmania amazonensis in a Sub-andean Focus of Bolivia Identified by kDNA-Polymerase Chain Reaction
by Telleria, J and Bosseno, Marie-France and Tarifa, T and Buitrago, R and Martínez, E and Torrez, M and Le Pont, F and Brenière, Simone Frédérique
RESEARCH NOTE - Putative Reservoirs of Leishmania amazonensis in a Sub-andean Focus of Bolivia Identified by kDNA-Polymerase Chain Reaction, 12/1999
From 1994 to 1996, an outbreak of leishmaniasis was described in Cajuata and surrounding communities in Inquisivi province, La Paz Department, Bolivia; eight... 
Leishmania amazonensis - Leishmania complex - reservoirs - Sub-andean region - polymerase chain reaction - Bolivia
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17. Ecological Interactions of Visceral Leishmaniasis in the State of Bahia, Brazil
by Sherlock, Italo A
Ecological Interactions of Visceral Leishmaniasis in the State of Bahia, Brazil, 12/1996
The laboratory and field observations summarized in this paper on visceral leishmaniasis ecology in the State of Bahia,Brazil are based on the author's... 
visceral leishmaniasis - ecology - epidemiology - geographical distribution - dispersion - reservoirs - Leishmania chagasi - Leishmania amazonensis s.l. - Lutzomyia longipalpis
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18. Full Text Insights into the tracking of the cysteine proteinase B COOH-terminal polypeptide of Leishmania (Leishmania) amazonensis by surface plasmon resonance
by Santos-de-Souza, Raquel and Souza-Silva, Franklin and de Albuquerque-Melo, Barbara Cristina and Ribeiro-Guimarães, Michelle Lopes and de Castro Côrtes, Luzia Monteiro and Pereira, Bernardo Acácio Santini and Silva-Almeida, Mariana and Cysne-Finkelstein, Léa and de Oliveira Junior, Francisco Odencio Rodrigues and Pereira, Mirian Claudia de Souza and Alves, Carlos Roberto
Parasitology Research, ISSN 0932-0113, 4/2019, Volume 118, Issue 4, pp. 1249 - 1259
Leishmania (Leishmania) amazonensis has adaptive mechanisms to the host environment that are guided by its proteinases, including cysteine proteinase B (CPB),... 
Medical Microbiology | Leishmania ( L. ) amazonensis | Biomedicine | Immunology | Microbiology | Trans-epoxysuccinyl-L-leucylamido(4-guanidino)butane | Cysteine proteinase | Surface plasmon resonance | Leishmania (L.) amazonensis | amazonensis | DISTINCT | IDENTIFICATION | Leishmania (L | PROTEASES | ROLES | GENES | ANTIMICROBIAL PEPTIDE | DIFFERENTIATION | PROMASTIGOTES | EXPRESSION | PARASITOLOGY | EPITOPES | Cysteine proteinases | Usage | Polypeptides | Leishmania | Analysis | Diagnosis
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19. Full Text Synthesis, antileishmanial activity and mechanism of action studies of novel β-carboline-1,3,5-triazine hybrids
by Baréa, Paula and Barbosa, Valéria Aquilino and Bidóia, Danielle Lazarin and de Paula, Jéssica Carreira and Stefanello, Talitha Fernandes and da Costa, Willian Ferreira and Nakamura, Celso Vataru and Sarragiotto, Maria Helena
European Journal of Medicinal Chemistry, ISSN 0223-5234, 04/2018, Volume 150, pp. 579 - 590
A series of novel hybrids -carboline-1,3,5-triazine were synthesized and evaluated for their antileishmanial activity against promastigote and amastigote forms... 
Antileishmanial | β-carboline | Cell death mechanism | 1,3,5-Triazine | Leishmania amazonensis | CHEMISTRY, MEDICINAL | DONOVANI | LEISHMANIA-AMAZONENSIS | TRIAZINE | TETRAHYDRO-BETA-CARBOLINES | IN-VITRO | beta-carboline | REDUCTASE | AGENTS | DERIVATIVES | ALKALOIDS | Index Medicus
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20. Antigenic extracts of Leishmania braziliensis and Leishmania amazonensis associated with saponin partially protects BALB/c mice against Leishmania chagasi infection by suppressing IL-10 and IL-4 production
by Grenfell, Rafaella F. Q and Marques-da-Silva, Eduardo A and Souza-Testasicca, Miriam C and Coelho, Eduardo A. F and Fernandes, Ana Paula and Afonso, Luís Carlos C and Rezende, Simone A
01/2011
This study evaluated two vaccine candidates for their effectiveness in protecting BALB/c mice against Leishmania chagasi infection. These immunogenic... 
vaccine - Leishmania chagasi - Leishmania braziliensis - Leishmania amazonensis - IL-10 - IL-4
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