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Biochemical Journal, ISSN 0264-6021, 03/2014, Volume 458, Issue 3, pp. 559 - 573
Precise homoeostasis of the intracellular concentration of Cl- is achieved via the co-ordinated activities of the Cl- influx and efflux. We demonstrate that... 
co-transporter (NCC) | Cl | Blood pressure/hypertension | K | Ion homoeostasis | Signal transduction | Na | co-transporter 1 (NKCC1) | Protein kinase | γ-aminobutyric acid (GABA) | 2Cl | co-transporter 2 (KCC2) | co-transporter 3 (KCC3) | SALT TRANSPORT | CELL-VOLUME | signal transduction | CATION-CHLORIDE COTRANSPORTERS | ION-TRANSPORT | BIOCHEMISTRY & MOLECULAR BIOLOGY | blood pressure/hypertension | ion homoeostasis | HYPOKALEMIC ALKALOSIS | K+-Cl- co-transporter 3 (KCC3) | Na+-K+-2Cl(-) co-transporter 1 (NKCC1) | K+-Cl- co-transporter 2 (KCC2) | protein kinase | BLOOD-PRESSURE | PROTEIN-KINASES | BARTTERS-SYNDROME | Na+-Cl- co-transporter (NCC) | ALANINE-RICH KINASE | MOLECULAR PHYSIOLOGY | gamma-aminobutyric acid (GABA) | Potassium - metabolism | Amino Acid Sequence | Cell Line | Phosphorylation | Signal Transduction | Humans | Molecular Sequence Data | Sodium-Potassium-Chloride Symporters - metabolism | Symporters - metabolism | Transcription Factors - metabolism | Protein Isoforms - metabolism | Chlorides - metabolism | Symporters - antagonists & inhibitors | Phosphopeptides - metabolism | Protein Isoforms - antagonists & inhibitors | Protein-Serine-Threonine Kinases - metabolism | Index Medicus | N[K]CC, Na+–K+ ion co-transporter | HEK, human embryonic kidney | TTBS, Tris-buffered saline containing Tween 20 | HRP, horseradish peroxidase | ES, embryonic stem | Na+–Cl− co-transporter (NCC) | CCT, conserved C-terminal | NCC, Na+–Cl− co-transporter | Na+–K+–2Cl− co-transporter 1 (NKCC1) | OSR1, oxidative stress-responsive kinase 1 | CCC, cation–Cl− co-transporter | K+–Cl− co-transporter 3 (KCC3) | KCC, K+–Cl− co-transporter | blood pressure | ERK1, extracellular-signal-regulated kinase 1 | SLC12, solute carrier family 12 | LDS, lithium dodecyl sulfate | NKCC, Na+–K+–2Cl− co-transporter | SPAK, SPS1-related proline | NTD, N-terminal cytoplasmic domain | WNK, WNK lysine-deficient protein kinase | CTD, C-terminal cytoplasmic domain | hypertension | XIC, extracted ion chromatogram | K+–Cl− co-transporter 2 (KCC2) | alanine-rich kinase
Journal Article
BioEssays, ISSN 0265-9247, 11/2011, Volume 33, Issue 11, pp. 870 - 879
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2007, Volume 104, Issue 31, pp. 12761 - 12766
The recent determination of the crystal structure of the leucine transporter from Aquifex aeolicus (aaLeuT) has provided significant insights into the function... 
Proteins | HeLa cells | Ions | Coordinate systems | Serotonin plasma membrane transport proteins | Porters | Modeling | Binding sites | Carboxylates | Membrane proteins | Neurotransmitter:sodium symporters | calculation | Neurotransmitters | Serotonin | Homology modeling | neurotransmitter : sodium symporters | CYSTEINE-SCANNING MUTAGENESIS | SEROTONIN TRANSPORTER | NEUROTRANSMITTER TRANSPORTERS | SODIUM | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | DOPAMINE TRANSPORTER | AMINO-ACID TRANSPORTER | serotonin | PROTEIN STRUCTURES | homology modeling | neurotransmitters | BACTERIAL HOMOLOG | RESIDUES | pK(A) calculation | Protein Structure, Tertiary | Protons | Amino Acid Sequence | Ions - chemistry | Amino Acid Transport Systems, Basic - genetics | Amino Acid Transport Systems, Basic - chemistry | Humans | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Models, Molecular | Molecular Sequence Data | Chlorides - chemistry | Plasma Membrane Neurotransmitter Transport Proteins - metabolism | Mutation - genetics | Membrane Transport Proteins - chemistry | Chlorides - metabolism | Bacterial Proteins - metabolism | Membrane Transport Proteins - metabolism | Plasma Membrane Neurotransmitter Transport Proteins - chemistry | Amino Acid Transport Systems, Basic - metabolism | Binding Sites | Index Medicus | Biological Sciences | neurotransmitter:sodium symporters | pKA calculation
Journal Article