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1. Full Text Multidrug resistance in bacteria
by Nikaido, Hiroshi
Annual Review of Biochemistry, ISSN 0066-4154, 2009, Volume 78, Issue 1, pp. 119 - 146
Large amounts of antibiotics used for human therapy, as well as for farm animals and even for fish in aquaculture, resulted in the selection of pathogenic... 
Integrons | R plasmids | Multidrug efflux pumps | Transposons | Type IV secretion system | BIOCHEMISTRY & MOLECULAR BIOLOGY | LARGE PERIPLASMIC LOOPS | ESCHERICHIA-COLI | type IV secretion system | transposons | ANTIMICROBIAL RESISTANCE | integrons | GRAM-NEGATIVE BACTERIA | MEMBRANE-FUSION PROTEIN | PSEUDOMONAS-AERUGINOSA | multidrug efflux pumps | EFFLUX PUMP ACRB | SPECTRUM BETA-LACTAMASES | STAPHYLOCOCCUS-AUREUS | AMINOGLYCOSIDE-MODIFYING ENZYMES | Bacteria - metabolism | Genes, MDR | Humans | Bacteria - drug effects | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Bacteria - genetics | Anti-Bacterial Agents - therapeutic use | ATP-Binding Cassette Transporters - chemistry | Animals | ATP-Binding Cassette Transporters - genetics | Drug Resistance, Multiple, Bacterial | ATP-Binding Cassette Transporters - metabolism | Bacterial Proteins - metabolism | Drug resistance in microorganisms | Research | Gene expression | Plasmids | Analysis
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2. Enzyme-mediated resistance to antibiotics
: mechanisms, dissemination, and prospects for inhibition
2007, ISBN 1555813038, xviii, 357
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3. Full Text Co-occurrence of resistance genes to antibiotics, biocides and metals reveals novel insights into their co-selection potential
by Pal, Chandan and Bengtsson-Palme, Johan and Kristiansson, Erik and Larsson, D.G.Joakim and Department of Mathematical Sciences, Mathematical Statistics and Naturvetenskapliga fakulteten and Institutionen för biomedicin, avdelningen för infektionssjukdomar and Faculty of Sciences and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy and Institute of Biomedicine, Department of Infectious Medicine and Sahlgrenska akademin and Institutionen för matematiska vetenskaper, matematisk statistik
BMC Genomics, ISSN 1471-2164, 11/2015, Volume 16, Issue 1, p. 964
Background: Antibacterial biocides and metals can co-select for antibiotic resistance when bacteria harbour resistance or tolerance genes towards both types of... 
Biocide resistance | Toxin-antitoxin | Co-selection | Plasmids | Metal resistance | Antibiotic resistance | Bacterial genomes | CROSS-RESISTANCE | FLUOROQUINOLONE RESISTANCE | MECHANISMS | SPECTRUM-BETA-LACTAMASES | SILVER RESISTANCE | DATABASE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | SYSTEMS | KLEBSIELLA-PNEUMONIAE | PROKARYOTES | Genes, Bacterial - genetics | Genomics | Humans | Bacteria - drug effects | Selection, Genetic | Databases, Genetic | Drug Resistance, Microbial - genetics | Sulfonamides - pharmacology | Bacteria - genetics | Disinfectants - pharmacology | Plasmids - genetics | Bacterial Toxins - genetics | Environment | Anti-Bacterial Agents - pharmacology | beta-Lactam Resistance - genetics | Aminoglycosides - pharmacology | Antitoxins - metabolism | Evolution, Molecular | Metals - pharmacology | Drug resistance in microorganisms | Microbial genetics | Immune complexes | Innovations | Genetic aspects | Properties | Miljövetenskap | Microbiology | Microbiology in the medical area | Antibiotic resistance; Biocide resistance; Metal resistance; Bacterial genomes; Plasmids; Co-selection; Toxin-antitoxin | Mikrobiologi | Bioinformatik och systembiologi | Mikrobiologi inom det medicinska området | Bioinformatics and Systems Biology | Environmental Sciences
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4. Full Text Multiple Mechanisms of Antimicrobial Resistance in Pseudomonas aeruginosa: Our Worst Nightmare?
by David M. Livermore
Clinical Infectious Diseases, ISSN 1058-4838, 3/2002, Volume 34, Issue 5, pp. 634 - 640
Pseudomonas aeruginosa carries multiresistance plasmids less often than does Klebsiella pneumoniae, develops mutational resistance to cephalosporins less... 
Fluoroquinolones | Enzymes | Antibiotics | Pumps | Antimicrobial Resistance | Antibiotic resistance | Pseudomonas aeruginosa | Aminoglycosides | Infections | Genetic mutation | Polymyxins | INFECTIOUS DISEASES | INTERPLAY | IMIPENEM | METALLO-BETA-LACTAMASE | GENE | ACINETOBACTER | PROTEIN-F | MICROBIOLOGY | IMMUNOLOGY | Multigene Family | Drug Resistance, Multiple - genetics | Gene Frequency | Humans | Integrins - genetics | Pseudomonas aeruginosa - physiology | Pseudomonas aeruginosa - drug effects | Cell Membrane Permeability - genetics | Microbial Sensitivity Tests | Pseudomonas aeruginosa - genetics | Anti-Bacterial Agents - pharmacology | Mutation | Drug Resistance, Bacterial - genetics | Physiological aspects | Drug resistance in microorganisms | Research | Drug therapy
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5. Full Text Efflux-mediated antimicrobial resistance
by Poole, Keith
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 07/2005, Volume 56, Issue 1, pp. 20 - 51
Antibiotic resistance continues to plague antimicrobial chemotherapy of infectious disease. And while true biocide resistance is as yet unrealized, in vitro... 
Resistance | Efflux | Multidrug | Antibiotics | Antimicrobials | Biocides | STAPHYLOCOCCUS-AUREUS MUTANTS | INFECTIOUS DISEASES | BACTERIAL MULTIDRUG-RESISTANCE | QUATERNARY AMMONIUM-COMPOUNDS | MICROBIOLOGY | antimicrobials | biocides | ENTERICA SEROVARS TYPHIMURIUM | efflux | resistance | multidrug | VIRIDANS GROUP STREPTOCOCCI | BINDING CASSETTE TRANSPORTER | BETA-LACTAM ANTIBIOTICS | LEVEL FLUOROQUINOLONE RESISTANCE | PHARMACOLOGY & PHARMACY | MULTIPLE-ANTIBIOTIC-RESISTANCE | antibiotics | IN-VITRO ACTIVITY | Aminoglycosides - pharmacokinetics | Biological Transport | Drug Resistance, Multiple, Bacterial | Fluoroquinolones - pharmacology | Tetracycline - pharmacology | Anti-Bacterial Agents - pharmacokinetics | Chloramphenicol - pharmacology | Drug Resistance, Bacterial | Chloramphenicol - pharmacokinetics | Tetracycline - pharmacokinetics | Aminoglycosides - pharmacology | Fluoroquinolones - pharmacokinetics
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6. Full Text Resistance plasmid families in Enterobacteriaceae
by Carattoli, Alessandra
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 06/2009, Volume 53, Issue 6, pp. 2227 - 2238
SPECTRUM-BETA-LACTAMASE | RIBOSOMAL-RNA METHYLATION | CTX-M | MEDIATED QUINOLONE RESISTANCE | ESCHERICHIA-COLI STRAINS | FI-R FACTORS | ANTIBIOTIC-RESISTANCE | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | COMPLETE NUCLEOTIDE-SEQUENCE | KLEBSIELLA-PNEUMONIAE | CONJUGATIVE PLASMIDS | Animals | Carbapenems - pharmacology | beta-Lactamases - genetics | Plasmids | Humans | Bacterial Proteins - genetics | Enterobacteriaceae - drug effects | Methyltransferases - genetics | Enterobacteriaceae - genetics | Aminoglycosides - pharmacology | Drug Resistance, Bacterial - genetics | Minireview
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7. Aminoglycoside Resistance: The Emergence of Acquired 16S Ribosomal RNA Methyltransferases
by Doi, Yohei and Wachino, Jun-ichi and Arakawa, Yoshichika
Infectious Disease Clinics of North America, ISSN 0891-5520, 06/2016, Volume 30, Issue 2, pp. 523 - 537
Aminoglycoside-producing Actinobacteria are known to protect themselves from their own aminoglycoside metabolites by producing 16S ribosomal RNA... 
16S ribosomal RNA | Posttranscriptional methylation | Aminoglycoside | Carbapenemease | MOLECULAR CHARACTERIZATION | INFECTIOUS DISEASES | ESCHERICHIA-COLI | HIGH-LEVEL RESISTANCE | SERRATIA-MARCESCENS | IMMUNOLOGY | METHYLASE GENES | CITROBACTER-FREUNDII | METALLO-BETA-LACTAMASE | PSEUDOMONAS-AERUGINOSA | LACTAMASE-PRODUCING ENTEROBACTERIACEAE | KLEBSIELLA-PNEUMONIAE | RNA Processing, Post-Transcriptional | Bacterial Infections - drug therapy | Humans | Bacteria - drug effects | Drug Resistance, Bacterial | Anti-Bacterial Agents - therapeutic use | Methyltransferases | Bacteria - enzymology | Anti-Bacterial Agents - pharmacology | Bacteria - pathogenicity | Aminoglycosides - pharmacology | RNA, Ribosomal, 16S | Bacterial Infections - microbiology | Aminoglycosides - therapeutic use
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8. Full Text Molecular mechanisms of antibiotic resistance
by Wright, Gerard D
Chemical Communications, ISSN 1359-7345, 2011, Volume 47, Issue 14, pp. 4055 - 4061
Over the past decade, resistance to antibiotics has emerged as a crisis of global proportion. Microbes resistant to many and even all clinically approved... 
VANCOMYCIN | ENZYME | BAD BUGS | AMINOGLYCOSIDE | STRUCTURAL-ANALYSIS | KINETIC MECHANISM | CRYSTAL-STRUCTURES | BETA-LACTAMASES | ACRB | CHEMISTRY, MULTIDISCIPLINARY | ACETYLTRANSFERASE | DNA Gyrase - metabolism | Bacteria - metabolism | Biocatalysis | Bacterial Outer Membrane Proteins - metabolism | Hemeproteins - metabolism | Drug Resistance, Bacterial | Bacteria - enzymology | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | beta-Lactamases - metabolism
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9. Full Text Emerging broad-spectrum resistance in Pseudomonas aeruginosa and Acinetobacter baumannii : Mechanisms and epidemiology
by Potron, Anaïs and Poirel, Laurent and Nordmann, Patrice
International Journal of Antimicrobial Agents, ISSN 0924-8579, 2015, Volume 45, Issue 6, pp. 568 - 585
Highlights • Multidrug resistance is increasingly reported among Acinetobacter baumannii and Pseudomonas aeruginosa clinical isolates. • Extended-spectrum... 
Infectious Disease | Pseudomonas aeruginosa | Aminoglycosides | Acinetobacter baumannii | Carbapenems | β-Lactams | Multidrug resistance | 2-COMPONENT REGULATORY SYSTEM | INFECTIOUS DISEASES | MICROBIOLOGY | beta-Lactams | SEQUENCE TYPE 235 | NATURALLY-OCCURRING OXACILLINASE | MULTIDRUG EFFLUX PUMP | GRAM-NEGATIVE BACTERIA | METALLO-BETA-LACTAMASE | ANTIMICROBIAL SURVEILLANCE PROGRAM | PHARMACOLOGY & PHARMACY | INTERNATIONAL CLONAL COMPLEX | RIBOSOMAL-RNA METHYLASE | CLASS 1 INTEGRON | Pseudomonas aeruginosa - isolation & purification | Humans | Pseudomonas aeruginosa - drug effects | Pseudomonas Infections - microbiology | beta-Lactams - pharmacology | Pseudomonas Infections - epidemiology | Acinetobacter Infections - epidemiology | Cross Infection - microbiology | Drug Resistance, Multiple, Bacterial | Acinetobacter baumannii - isolation & purification | Anti-Bacterial Agents - pharmacology | Acinetobacter baumannii - drug effects | Aminoglycosides - pharmacology | Acinetobacter Infections - microbiology | Cross Infection - epidemiology | RNA | Drug resistance | Epidemiology
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10. Full Text Antibiotic resistance-What's dosing got to do with it?
by Roberts, Jason A and Kruger, Peter and Paterson, David L and Lipman, Jeffrey
Critical Care Medicine, ISSN 0090-3493, 2008, Volume 36, Issue 8, pp. 2433 - 2440
Objective: This review seeks to identify original research articles that link antibiotic dosing and the development of antibiotic resistance for different... 
Resistance | Dosing | Antibiotic | Pharmacodynamics | Exposure | antibiotic | VITRO DYNAMIC-MODEL | PHARMACODYNAMIC MODEL | pharmacodynamics | MUTANT SELECTION WINDOW | dosing | resistance | INTRAVENOUS CIPROFLOXACIN | IN-VITRO | STREPTOCOCCUS-PNEUMONIAE | exposure | PSEUDOMONAS-AERUGINOSA | BETA-LACTAM ANTIBIOTICS | STAPHYLOCOCCUS-AUREUS | AMINOGLYCOSIDE-MODIFYING ENZYMES | CRITICAL CARE MEDICINE | Dose-Response Relationship, Drug | Drug Resistance, Microbial | Anti-Bacterial Agents - classification | Area Under Curve | Humans | Anti-Bacterial Agents - pharmacokinetics | Anti-Bacterial Agents - pharmacology | Mutation
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