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Glia, ISSN 0894-1491, 11/2016, Volume 64, Issue 11, pp. 1841 - 1856
Journal Article
Cell Metabolism, ISSN 1550-4131, 06/2012, Volume 15, Issue 6, pp. 827 - 837
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, p. e95319
Oxidative stress and the antioxidant response induced by high environmental ammonia (HEA) were investigated in the liver and gills of three freshwater teleosts... 
SUBLETHAL AMMONIA | RAINBOW-TROUT | LIPID-PEROXIDATION | MULTIDISCIPLINARY SCIENCES | HIGH ENVIRONMENTAL AMMONIA | TOXICITY | PRIMARY CULTURES | SEA BASS | TROUT ONCORHYNCHUS-MYKISS | SALMO-SALAR L | FREE-RADICALS | Adaptation, Physiological | Superoxide Dismutase - genetics | Oxidative Stress | Species Specificity | Glutathione - metabolism | Glutathione Reductase - metabolism | Glutathione Reductase - genetics | Ascorbate Peroxidases - metabolism | Gills - drug effects | Goldfish - genetics | Liver - drug effects | Ascorbate Peroxidases - genetics | Xanthine Oxidase - genetics | Superoxide Dismutase - metabolism | Malondialdehyde - metabolism | Oncorhynchus mykiss - metabolism | Carps - metabolism | Glutathione Peroxidase - metabolism | Xanthine Oxidase - metabolism | Goldfish - metabolism | Catalase - genetics | Liver - metabolism | Ammonia - toxicity | Gills - metabolism | Oncorhynchus mykiss - genetics | Glutathione Peroxidase - genetics | Hydrogen Peroxide - metabolism | Catalase - metabolism | Gene Expression Regulation - drug effects | Animals | Carps - genetics | Physiological aspects | Oxidative stress | Genetic aspects | Molybdenum compounds | Trout | Analysis | Hydrogen peroxide | Ascorbic acid | Liver | L-Ascorbate peroxidase | Superoxide dismutase | Accumulation | Antioxidants | Catalase | Glutathione reductase | Rodents | Fish | Peroxidase | Species | Glutathione | Glutathione peroxidase | Carp | Salmon | Gills | Exposure | Xanthine | Malondialdehyde | Ammonia | Xanthine oxidase | Reductase | System effectiveness
Journal Article
Nature, ISSN 0028-0836, 06/2017, Volume 546, Issue 7656, pp. 168 - 172
Metabolic reprogramming by oncogenic signals promotes cancer initiation and progression. The oncogene KRAS and tumour suppressor STK11, which encodes the... 
REPLICATION | METABOLISM | PATHWAY | MULTIDISCIPLINARY SCIENCES | GROWTH | AMPK | LKB1 | Carbamyl Phosphate - metabolism | Metabolomics | AMP-Activated Protein Kinases - metabolism | Cell Proliferation | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Male | Pyrimidines - metabolism | S Phase | Cell Death | DNA - biosynthesis | Female | Transcription, Genetic | Protein-Serine-Threonine Kinases - metabolism | Carbamoyl-Phosphate Synthase (Ammonia) - genetics | Carcinoma, Non-Small-Cell Lung - pathology | DNA Damage - drug effects | Lung Neoplasms - genetics | Nitrogen - metabolism | Lung Neoplasms - enzymology | Ammonia - metabolism | Carcinoma, Non-Small-Cell Lung - genetics | Purines - metabolism | Carcinoma, Non-Small-Cell Lung - metabolism | Gene Silencing | Protein-Serine-Threonine Kinases - genetics | DNA Replication | Mitochondria - metabolism | Pyrimidines - pharmacology | Xenograft Model Antitumor Assays | Animals | Carbamoyl-Phosphate Synthase (Ammonia) - metabolism | Bicarbonates - metabolism | Mice | Carcinoma, Non-Small-Cell Lung - enzymology | DNA-Directed DNA Polymerase - metabolism | Carbamoyl-Phosphate Synthase (Ammonia) - deficiency | Pyrimidines | Gene mutations | Lung cancer | Cancer cells | Genetic aspects | Nucleotide sequencing | Health aspects | Methods | DNA sequencing | Correlation | Transcription | Toxicity | DNA damage | Oncology | K-Ras protein | LKB1 protein | Bicarbonate | Mitochondria | Phosphate | Carbonates | Signatures | Damage | Stalling | Deoxyribonucleic acid--DNA | Enzymes | Mortality | Non-small cell lung carcinoma | Nitrogen | Pools | Metabolism | Gene expression | Flow | Polymerase | DNA biosynthesis | Ammonia | Urea | Depletion | Lungs | Carbamoyl phosphate | Cell death | Human behavior | Tumors | Cancer | Index Medicus
Journal Article
The Plant Journal, ISSN 0960-7412, 10/2007, Volume 52, Issue 2, pp. 263 - 285
Journal Article
Advances in Experimental Medicine and Biology, ISSN 0065-2598, 10/2016, Volume 949, pp. 227 - 243
Astrocytes play crucial roles in maintaining brain homeostasis and in orchestrating neural development, all through tightly coordinated steps that cooperate to... 
Myelin damage | Astrocyte dysfunction | Astrocytes | Neurodegeneration | Neurodevelopmental diseases | MEDICINE, RESEARCH & EXPERIMENTAL | GLUTARIC-ACIDURIA | AMYOTROPHIC-LATERAL-SCLEROSIS | MODEL | BLOOD-BRAIN-BARRIER | NEUROSCIENCES | CELL BIOLOGY | PERIVASCULAR ASTROCYTES | PYRUVATE-CARBOXYLASE DEFICIENCY | NEURONS | WHITE-MATTER DISEASE | ACIDURIA TYPE-I | ACIDEMIA TYPE-I | Niemann-Pick Disease, Type C - therapy | Humans | Astrocytes - pathology | Niemann-Pick Disease, Type C - pathology | Niemann-Pick Disease, Type C - metabolism | Brain - metabolism | Pyruvate Carboxylase Deficiency Disease - diagnosis | Brain Diseases, Metabolic - diagnosis | Amino Acid Metabolism, Inborn Errors - pathology | Diet - methods | Neurodegenerative Diseases - pathology | Iron Metabolism Disorders - diagnosis | Alexander Disease - metabolism | Neurodegenerative Diseases - therapy | Brain - drug effects | Hepatic Encephalopathy - pathology | Brain - pathology | Ceruloplasmin - metabolism | Iron Metabolism Disorders - metabolism | Disease Management | Alexander Disease - diagnosis | Astrocytes - metabolism | Glutaryl-CoA Dehydrogenase - deficiency | Brain Diseases, Metabolic - pathology | Glutaryl-CoA Dehydrogenase - metabolism | Ceruloplasmin - deficiency | Hepatic Encephalopathy - metabolism | Pyruvate Carboxylase Deficiency Disease - metabolism | Pyruvate Carboxylase Deficiency Disease - pathology | Homeostasis | Neurodegenerative Diseases - diagnosis | Amino Acid Metabolism, Inborn Errors - diagnosis | Brain Diseases, Metabolic - therapy | Amino Acid Metabolism, Inborn Errors - metabolism | Hepatic Encephalopathy - diagnosis | Neurogenesis - drug effects | Niemann-Pick Disease, Type C - diagnosis | Glutamate-Ammonia Ligase - metabolism | Astrocytes - drug effects | Glutamate-Ammonia Ligase - deficiency | Pyruvate Carboxylase Deficiency Disease - therapy | Neurodegenerative Diseases - metabolism | Brain Diseases, Metabolic - metabolism | Amino Acid Metabolism, Inborn Errors - therapy | Alexander Disease - pathology | Antioxidants - therapeutic use | Hepatic Encephalopathy - therapy | Iron Metabolism Disorders - therapy | Alexander Disease - therapy | Sorption Detoxification | Glucose - therapeutic use | Iron Metabolism Disorders - pathology
Journal Article
Journal Article
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 510, Issue 7503, pp. 172 - 175
Previous studies have established that the folding, structure and function of membrane proteins are influenced by their lipid environments(1-7) and that lipids... 
MYCOBACTERIUM-TUBERCULOSIS | ATOM FORCE-FIELD | MOLECULAR-DYNAMICS | MULTIDISCIPLINARY SCIENCES | COMPLEXES | PURIFICATION | ION-CHANNEL | MOBILITY-MASS SPECTROMETRY | MODEL | MSCL | WATER | Apoproteins - chemistry | Cardiolipins - pharmacology | Protein Unfolding - drug effects | Protein Conformation - drug effects | Aquaporins - chemistry | Bacterial Proteins - chemistry | Substrate Specificity | Crystallography, X-Ray | Membrane Lipids - chemistry | Cation Transport Proteins - metabolism | Protein Folding - drug effects | Mass Spectrometry | Mycobacterium tuberculosis - chemistry | Membrane Proteins - metabolism | Ion Channels - chemistry | Phosphatidylglycerols - metabolism | Apoproteins - metabolism | Ammonia - metabolism | Models, Molecular | Aquaporins - metabolism | Escherichia coli Proteins - metabolism | Cardiolipins - metabolism | Escherichia coli - chemistry | Cardiolipins - chemistry | Phosphatidylglycerols - chemistry | Ion Channels - metabolism | Membrane Proteins - chemistry | Protein Stability - drug effects | Membrane Lipids - metabolism | Phosphatidylglycerols - pharmacology | Bacterial Proteins - metabolism | Membrane Lipids - pharmacology | Lipid Bilayers - chemistry | Cation Transport Proteins - chemistry | Escherichia coli Proteins - chemistry | Biological research | Physiological aspects | Lipids | Cooperative binding (Biochemistry) | Research | Structure | Molecular biology | Membrane proteins | Biology, Experimental | Proteins | Studies | Membranes | E coli | Binding sites | Crystal structure
Journal Article