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The New England Journal of Medicine, ISSN 0028-4793, 06/2006, Volume 354, Issue 24, pp. 2542 - 2551
Journal Article
British Journal of Cancer, ISSN 0007-0920, 06/2006, Volume 94, Issue 12, pp. 1765 - 1769
Journal Article
Cancer, ISSN 0008-543X, 10/2011, Volume 117, Issue 20, pp. 4633 - 4641
BACKGROUND: Patients with gastrointestinal stromal tumors (GISTs) resistant to both imatinib and sunitinib have a poor prognosis and few therapeutic options.... 
gastrointestinal | protein tyrosine | tumors | stromal | kinases | nilotinib | TYROSINE KINASE INHIBITORS | IMATINIB-RESISTANT | ONCOLOGY | KIT | AMN107 | MUTATIONS | PROGRESSION | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Neoplasm Grading | Time Factors | Gastrointestinal Stromal Tumors - pathology | Adult | Female | Indoles - pharmacology | Proto-Oncogene Proteins c-kit - genetics | Gastrointestinal Stromal Tumors - genetics | Drug Administration Schedule | Pyrimidines - administration & dosage | Kaplan-Meier Estimate | Treatment Outcome | Pyrimidines - pharmacology | Imatinib Mesylate | Piperazines - pharmacology | Disease-Free Survival | Drug Resistance, Neoplasm - genetics | Pyrroles - pharmacology | Gastrointestinal Stromal Tumors - drug therapy | Pyrimidines - therapeutic use | Receptor, Platelet-Derived Growth Factor alpha - genetics | Aged | Benzamides | Mutation | Neoplasm Staging | Salvage Therapy - methods | Protein-Tyrosine Kinases - antagonists & inhibitors | Nilotinib | Dosage and administration | Research | Drug therapy | Gastrointestinal tumors | Patient outcomes | Therapy | Imatinib | Medical treatment | Disease control | Patients | Survival | Anticancer properties | Confidence intervals | Intolerance | Medical prognosis | Antitumor activity | Tumors | Cancer
Journal Article
Seminars in Oncology, ISSN 0093-7754, 04/2011, Volume 38, Issue 1, pp. S3 - S9
The development of tyrosine kinase inhibitors (TKIs) for the treatment of chronic myelogenous leukemia (CML) was based on the discovery that CML stem and... 
MESYLATE | PDGFRA | IMATINIB-RESISTANT | TRANSPORT | ONCOLOGY | GIANT-CELL TUMOR | BCR-ABL | MUTATION | C-KIT | AMN107 | IN-VITRO ACTIVITY | Clinical Trials as Topic | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Humans | Neoplasms - drug therapy | Protein-Tyrosine Kinases - antagonists & inhibitors
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 09/2009, Volume 27, Issue 25, pp. 4204 - 4210
Journal Article
AUSTRALIAN PRESCRIBER, ISSN 0312-8008, 04/2008, Volume 31, Issue 2, pp. 50 - 51
Journal Article
Leukemia, ISSN 0887-6924, 2012, Volume 26, Issue 6, pp. 1189 - 1194
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 01/2010, Volume 28, Issue 3, pp. 392 - 397
Journal Article
Journal Article
BBA - Proteins and Proteomics, ISSN 1570-9639, 03/2010, Volume 1804, Issue 3, pp. 445 - 453
Journal Article
Journal Article
Journal Article