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Nature communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, pp. 5680 - 5680
We recently identified a high prevalence of mutations affecting the catalytic (C alpha) subunit of protein kinase A (PKA) in cortisol-secreting adrenocortical... 
CYCLASE | CYCLIC-AMP | MCCUNE-ALBRIGHT SYNDROME | HOLOENZYME | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | ADRENAL-TUMORS | PHOSPHODIESTERASE | HYPERPLASIA | SOMATIC MUTATIONS | CAMP | Adrenocortical Adenoma - enzymology | Humans | Cyclic AMP-Dependent Protein Kinases - chemistry | Cyclic AMP-Dependent Protein Kinase Catalytic Subunits - chemistry | Cyclic AMP-Dependent Protein Kinase Catalytic Subunits - genetics | Cyclic AMP-Dependent Protein Kinase Catalytic Subunits - metabolism | Cyclic AMP-Dependent Protein Kinases - genetics | Cushing Syndrome - enzymology | Cushing Syndrome - pathology | Adrenocortical Adenoma - genetics | Protein Stability | Cyclic AMP-Dependent Protein Kinase RIalpha Subunit - metabolism | Cyclic AMP - metabolism | Cyclic AMP-Dependent Protein Kinase RIalpha Subunit - chemistry | Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | Adrenal Cortex Neoplasms - enzymology | Catalytic Domain | Cushing Syndrome - genetics | Adrenal Cortex Neoplasms - pathology | Adrenocortical Adenoma - pathology | Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit - genetics | Adrenal Cortex Neoplasms - genetics | Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit - chemistry | Cyclic AMP-Dependent Protein Kinase RIalpha Subunit - genetics | Cell Line, Tumor | Protein Binding | Mutation | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 08/2007, Volume 27, Issue 35, pp. 9513 - 9524
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2014, Volume 370, Issue 11, pp. 1019 - 1028
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2017, Volume 356, Issue 6344, pp. 1288 - 1293
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2016, Volume 291, Issue 7, pp. 3668 - 3681
The intracellular infections of Mycobacterium tuberculosis, which is the causative agent of tuberculosis, are regulated by many cyclic dinucleotide signaling.... 
enzyme degradation | PROTEIN | LONG-TERM SURVIVAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | RESOLUTION | structure-function | GMP | SPORULATION | IDENTIFICATION | Mycobacterium tuberculosis | AFFECT BACTERIAL-GROWTH | phosphodiesterases | LEADS | cyclic diadenosine monophosphate (c-di-AMP) | AMP PHOSPHODIESTERASE | REVEALS | Exoribonucleases - genetics | Bacterial Proteins - chemistry | Exoribonucleases - chemistry | Molecular Sequence Data | Substrate Specificity | Dinucleoside Phosphates - chemistry | Recombinant Fusion Proteins - metabolism | Cyclic AMP - chemistry | Cyclic AMP - analogs & derivatives | Cyclic GMP - analogs & derivatives | Cyclic GMP - chemistry | Conserved Sequence | Cyclic AMP - metabolism | Peptide Fragments - genetics | Recombinant Proteins - metabolism | 3',5'-Cyclic-AMP Phosphodiesterases - metabolism | Amino Acid Sequence | Catalytic Domain | Peptide Fragments - metabolism | Biocatalysis | 3',5'-Cyclic-GMP Phosphodiesterases - genetics | Bacterial Proteins - genetics | Models, Molecular | Recombinant Proteins - chemistry | 3',5'-Cyclic-GMP Phosphodiesterases - chemistry | 3',5'-Cyclic-AMP Phosphodiesterases - genetics | Recombinant Fusion Proteins - chemistry | Dinucleoside Phosphates - metabolism | Peptide Fragments - chemistry | Sequence Alignment | 3',5'-Cyclic-AMP Phosphodiesterases - chemistry | 3',5'-Cyclic-GMP Phosphodiesterases - metabolism | Cyclic GMP - metabolism | Mycobacterium tuberculosis - enzymology | Bacterial Proteins - metabolism | Protein Conformation | Mutation | Exoribonucleases - metabolism | Enzymology
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2009, Volume 106, Issue 17, pp. 6927 - 6932
Journal Article
Acta Physiologica, ISSN 1748-1716, 05/2009, Volume 196, Issue 1, pp. 81 - 98
As the liver is central in the maintenance of glucose homeostasis and energy storage, knowledge of the physiology as well as physiopathology of hepatic energy... 
hepatic glucose production | fatty liver | type 2 diabetes | AMP-activated protein kinase | liver | energy metabolism | AMP‐activated protein kinase | Type 2 diabetes | Energy metabolism | Fatty liver | Hepatic glucose production | Liver | PHYSIOLOGY | LIPID-METABOLISM | CREB COACTIVATOR TORC2 | ACETYL-COA CARBOXYLASE | MICE LACKING ADIPONECTIN | LIVER-DISEASE | ISOLATED RAT HEPATOCYTES | SKELETAL-MUSCLE | FATTY-ACID OXIDATION | INSULIN-RESISTANCE | ADIPOSE-TISSUE | AMP-Activated Protein Kinases - metabolism | Liver - enzymology | Hypoglycemic Agents - metabolism | Humans | Homeostasis | Protein Subunits - metabolism | Liver Cirrhosis - metabolism | Aminoimidazole Carboxamide - metabolism | Energy Metabolism - physiology | Protein Subunits - genetics | Liver Cirrhosis - drug therapy | Dyslipidemias - drug therapy | Ribonucleotides - metabolism | Fatty Liver - metabolism | Fatty Liver - physiopathology | Lipid Metabolism | Mitochondria - metabolism | AMP-Activated Protein Kinases - chemistry | Fatty Liver - drug therapy | Gluconeogenesis - physiology | Animals | Aminoimidazole Carboxamide - analogs & derivatives | Dyslipidemias - metabolism | Glucose - metabolism | Protein Conformation | Liver - cytology | Protein Subunits - chemistry | Liver Cirrhosis - physiopathology | AMP-Activated Protein Kinases - genetics | Dyslipidemias - physiopathology | Glucose metabolism | Enzymes | Liver diseases | Physiological aspects | Protein biosynthesis | Insulin resistance | Glucose | Protein kinases | Health aspects | Fatty acids | Dextrose | cytology | Protein Subunits | Dyslipidemias | AMP-Activated Protein Kinases | therapeutic | Hypoglycemic Agents | Aminoimidazole Carboxamide | Mitochondria | genetics | Gluconeogenesis | chemistry | drug therapy | physiology | Liver Cirrhosis | enzymology | Fatty Liver | physiopathology | Ribonucleotides | Energy Metabolism | analogs & derivatives | MP-activated protein kinase | metabolism
Journal Article