X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (6358) 6358
Book Chapter (16) 16
Dissertation (9) 9
Magazine Article (2) 2
Book Review (1) 1
Conference Proceeding (1) 1
Publication (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (4388) 4388
amp-activated protein kinases - metabolism (3984) 3984
humans (3184) 3184
mice (2586) 2586
phosphorylation (2103) 2103
male (1960) 1960
amp-activated protein kinases - genetics (1949) 1949
ampk (1647) 1647
activated protein-kinase (1598) 1598
amp-activated protein kinase (1598) 1598
kinases (1520) 1520
signal transduction (1422) 1422
cell biology (1366) 1366
biochemistry & molecular biology (1345) 1345
metabolism (1318) 1318
proteins (1223) 1223
rats (1119) 1119
amp (1042) 1042
protein kinases (1022) 1022
protein-serine-threonine kinases - metabolism (1005) 1005
apoptosis (925) 925
mice, inbred c57bl (901) 901
female (895) 895
signal transduction - drug effects (880) 880
amp-activated protein kinases (853) 853
expression (835) 835
glucose (831) 831
gene expression (754) 754
cells, cultured (745) 745
physiological aspects (732) 732
cell line, tumor (720) 720
autophagy (710) 710
mice, knockout (701) 701
oxidative stress (690) 690
physiology (682) 682
endocrinology & metabolism (680) 680
cell line (677) 677
glucose - metabolism (672) 672
research (666) 666
skeletal-muscle (649) 649
activation (638) 638
obesity (633) 633
inhibition (632) 632
insulin (612) 612
rodents (610) 610
protein-serine-threonine kinases - genetics (607) 607
multidisciplinary sciences (598) 598
cancer (597) 597
metformin (594) 594
research article (590) 590
multienzyme complexes - metabolism (553) 553
diabetes (544) 544
insulin resistance (526) 526
enzyme activation (521) 521
insulin-resistance (521) 521
medicine (513) 513
phosphorylation - drug effects (513) 513
liver (511) 511
aminoimidazole carboxamide - analogs & derivatives (497) 497
muscle, skeletal - metabolism (495) 495
oncology (495) 495
tor serine-threonine kinases - metabolism (495) 495
homeostasis (485) 485
enzyme activation - drug effects (473) 473
fatty acids (471) 471
protein-kinase (471) 471
gene-expression (463) 463
inflammation (454) 454
analysis (453) 453
mitochondria (452) 452
science (439) 439
biology (438) 438
cells (437) 437
amp-activated protein kinases - antagonists & inhibitors (431) 431
health aspects (430) 430
apoptosis - drug effects (428) 428
aminoimidazole carboxamide - pharmacology (427) 427
energy metabolism (425) 425
disease models, animal (419) 419
liver - metabolism (419) 419
growth (413) 413
genetic aspects (406) 406
mutation (404) 404
gene expression regulation (394) 394
metformin - pharmacology (385) 385
ribonucleotides - pharmacology (385) 385
rats, sprague-dawley (384) 384
blotting, western (382) 382
rna, messenger - metabolism (374) 374
glucose metabolism (360) 360
rna interference (357) 357
biochemistry (352) 352
pathway (350) 350
mitochondria - metabolism (349) 349
proto-oncogene proteins c-akt - metabolism (348) 348
pharmacology & pharmacy (342) 342
reactive oxygen species - metabolism (342) 342
fatty-acid oxidation (341) 341
hypoglycemic agents - pharmacology (341) 341
lipids (334) 334
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (6350) 6350
Japanese (42) 42
Chinese (16) 16
French (9) 9
Russian (4) 4
German (2) 2
Polish (2) 2
Danish (1) 1
Hebrew (1) 1
Hungarian (1) 1
Korean (1) 1
Portuguese (1) 1
Spanish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Biochemical journal, ISSN 1470-8728, 2007, Volume 408, Issue 3, pp. 297 - 315
The specificities of 65 compounds reported to be relatively specific inhibitors of protein kinases have been profiled against a panel of 70-80 protein kinases... 
Drug discovery | Kinase profiling | Protein kinase | Anti-cancer drugs | Inhibitor specificity | RHO-ASSOCIATED KINASE | TUMOR PROGRESSION | FAMILY-MEMBERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-PROLIFERATION | protein kinase | P38 MAP KINASE | CYCLIN-DEPENDENT KINASES | RECEPTOR TYROSINE KINASES | drug discovery | kinase profiling | SB 203580 | anti-cancer drugs | ISOFORMS IN-VITRO | P90 RSK | inhibitor specificity | Amino Acid Sequence | Cell Line | Phosphorylation | Recombinant Proteins - antagonists & inhibitors | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Humans | Drug Design | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Mitogen-Activated Protein Kinases - metabolism | Spodoptera | Yes1, Yamaguchi sarcoma viral oncogene homologue 1 | CSK, C-terminal Src kinase | Lck, lymphocyte cell-specific protein-tyrosine kinase | EGF, epidermal growth factor | FGF-R, fibroblast-growth-factor receptor | PAK, p21-activated protein kinase | PDK, 3-phosphoinositide-dependent protein kinase | PI3K, phosphatidylinositol (phosphoinositide) 3-kinase | NEK, NIMA (never in mitosis in Aspergillus nidulans)-related kinase | RSK, p90 ribosomal S6 kinase | HEK-293 cells, human embryonic kidney-293 cells | VEGF, vascular endothelial growth factor (vasoendothelial growth factor) | EF2K, elongation-factor-2 kinase | CK, casein kinase | PTEN, phosphatase and tensin homologue deleted on chromosome 10 | ERK, extracellular-signal-regulated kinase | ATM, ataxia telangiectasia mutated | SRPK, serine-arginine protein kinase | IL-1, interleukin 1 | MNK, MAPK-integrating protein kinase | ROCK, Rho-dependent protein kinase | CaMKK, CaMK kinase | GST, glutathione transferase | MKK1, MAPK kinase-1 (also called MEK1, MAPK or ERK kinase 1) | GAK, cyclin G-associated kinase | FMK, fluoromethylketone | MST, mammalian homologue Ste20-like kinase | PKA, cAMP-dependent protein kinase | FKBP, FK506-binding protein | PPAR, peroxisome-proliferator-activated receptor | IKK, inhibitory κB kinase | PH, pleckstrin homology | MBP, myelin basic protein | AICAR, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside | MAPKAP-K, MAPK-activated protein kinase | Sf21, Spodoptera frugiperda (fall armyworm) 21 | MARK, microtubule-affinity-regulating kinase | PIM, provirus integration site for Moloney murine leukaemia virus | LPS, lipopolysaccharide | MSK, mitogen- and stress-activated protein kinase | MAPK, mitogen-activated protein kinase | MELK, maternal embryonic leucine-zipper kinase | His6, hexahistidine | CAK, cyclin-dependent kinase-activating kinase | Eph-A2, Ephrin A2 receptor | PLK, polo-like kinase | ATF2, activating transcription factor 2 | PKD, protein kinase D | Src, sarcoma kinase | AMPK, AMP-activated protein kinase | MMS, methyl methanesulfonate | CHK, checkpoint kinase | JNK, c-Jun N-terminal kinase | TORC1, mTOR (mammalian target of rapamycin)–raptor (regulatory associated protein of mTOR) complex | BRSK, brain-specific kinase | RIP2, receptor-interacting protein 2 | IGF-1, insulin-like growth factor-1 | S6K1, S6 kinase 1 | DYRK, dual-specificity tyrosine-phosphorylated and -regulated kinase | HIPK, homeodomain-interacting protein kinase | ZMP, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside monophosphate | PRAK, p38-regulated activated kinase | PKC, protein kinase C | Src-I1, Src inhibitor 1 | TANK, TRAF (tumour-necrosis-factor-receptor-associated factor)-family-member-associated nuclear factor κB activator | NFAT, nuclear factor for activated T-cells | PHK, phosphorylase kinase | GSK3, glycogen synthase kinase 3 | PKB, protein kinase B (also called Akt) | CaMK, calmodulin-dependent kinase | CDK, cyclin-dependent protein kinase | NDRG, N-myc downstream-regulated gene | SmMLCK, smooth-muscle myosin light-chain kinase | TBK1, TANK-binding kinase 1 | PRK, protein kinase C-related kinase | SGK, serum- and glucocorticoid-induced kinase
Journal Article
Biochemical journal, ISSN 1470-8728, 2010, Volume 427, Issue 1, pp. 69 - 78
More than 200 phosphorylated 14-3-3-binding sites in the literature were analysed to define 14-3-3 specificities, identify relevant protein kinases, and give insights into how cellular 14-3-3... 
Evolution | 14-3-3 protein | Disrupted-in-schizophrenia 1 (DISC1) | calmodulin-dependent protein kinase | AGC protein kinase | Ca | NEURONAL MIGRATION | SIGNALING PATHWAYS | MEMBRANE H+-ATPASE | REGULATING 14-3-3 BINDING | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | EUKARYOTIC PROTEIN-KINASES | evolution | NUCLEAR-LOCALIZATION | EXOENZYME-S | STRUCTURAL BASIS | Ca2+/calmodulin-dependent protein kinase | disrupted-in-schizophrenia 1 (DISC1) | ENDOPLASMIC-RETICULUM | Protein Kinases - metabolism | Phosphorylation | Immunoprecipitation | Humans | RNA, Messenger - genetics | Cells, Cultured | Computational Biology | Kidney - cytology | RNA, Messenger - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | 14-3-3 Proteins - metabolism | Nerve Tissue Proteins - metabolism | Kidney - metabolism | Carrier Proteins - metabolism | Protein Binding | Binding Sites | Dimerization | Calcium-Calmodulin-Dependent Protein Kinases - metabolism | 14-3-3 Proteins - genetics | Bcl-2-associated death promoter | AANAT, serotonin acetyltransferase | FOXO, Forkhead box O | KLC, kinesin light chain | CDK5, cyclin-dependent kinase 5 | HEK, human embryonic kidney | MARK, microtubule affinity-regulating kinase | AMPK, AMP-activated protein kinase | EST, expressed sequence tag | PKB, protein kinase B | RSK, ribosomal S6 kinase | CaMK, Ca2 | GLUT4, glucose transporter 4 | protein kinase G | GST, glutathione transferase | HDAC, histone deacetylase | HAP1A, Huntingtin-associated protein 1A | DIG, digoxigenin | PKC, protein kinase C | BAD, Bcl-XL | PP2A, protein phosphatase 2A | DSTT, Division of Signal Transduction Therapy | HA, haemagglutinin | AGC, protein kinase A | Ca2 | PI4K, phosphoinositide 4-kinase | DISC1, disrupted-in-schizophrenia 1 | protein kinase C family kinase | YAP1, yes-associated protein 1
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2011, Volume 286, Issue 21, pp. 18465 - 18473
.... Overexpression of resistin using adenoviral vector in neonatal rat ventricular myocytes was associated with inhibition of AMP-activated protein kinase (AMPK... 
MAMMALIAN TARGET | INSULIN-RECEPTOR | OBESITY | PHOSPHORYLATION | GLUCOSE | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEART-FAILURE | THERAPEUTIC TARGET | DIABETIC CARDIOMYOPATHY | P70 S6 KINASE | MTOR | AMP-Activated Protein Kinases - metabolism | Resistin - genetics | TOR Serine-Threonine Kinases - metabolism | Ventricular Myosins - biosynthesis | Apoptosis - drug effects | Apoptosis - genetics | Cardiomegaly - pathology | JNK Mitogen-Activated Protein Kinases - metabolism | Insulin Receptor Substrate Proteins - metabolism | TOR Serine-Threonine Kinases - antagonists & inhibitors | Phosphorylation - genetics | TOR Serine-Threonine Kinases - genetics | JNK Mitogen-Activated Protein Kinases - genetics | Phosphorylation - drug effects | Insulin Receptor Substrate Proteins - genetics | Biomarkers - metabolism | Natriuretic Peptide, Brain - genetics | Resistin - metabolism | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Signal Transduction | Gene Expression Regulation - genetics | Ribosomal Protein S6 Kinases, 70-kDa - antagonists & inhibitors | AMP-Activated Protein Kinases - antagonists & inhibitors | Cells, Cultured | Enzyme Inhibitors - pharmacology | Natriuretic Peptide, Brain - biosynthesis | Rats | Ribosomal Protein S6 Kinases, 70-kDa - genetics | Rats, Sprague-Dawley | Gene Expression Regulation - drug effects | Myocytes, Cardiac - pathology | Animals | Insulin Receptor Substrate Proteins - antagonists & inhibitors | Insulin Resistance - genetics | Myocytes, Cardiac - metabolism | Cardiomegaly - genetics | AMP-Activated Protein Kinases - genetics | Cardiomegaly - metabolism | Ventricular Myosins - genetics | Molecular Bases of Disease | Cardiomyocyte | Insulin Resistance | AMP-activated Kinase (AMPK) | Gene Transfer | Diabetes | mTOR, JNK Signaling | Cardiac Hypertrophy | Diabetic Cardiomyopathy | Resistin
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 2010, Volume 120, Issue 7, pp. 2355 - 2369
.... Recently the LKB1/AMP-activated protein kinase (LKB1/AMPK) pathway was proposed to mediate the action of metformin on hepatic gluconeogenesis... 
MEDICINE, RESEARCH & EXPERIMENTAL | RESPIRATORY-CHAIN | SKELETAL-MUSCLE | PHOSPHOENOLPYRUVATE CARBOXYKINASE | CYCLIC-AMP | ACTIVATED PROTEIN-KINASE | PHOSPHORYLATION | AICA RIBOSIDE | UPSTREAM KINASE | LKB1 | GLUCOSE-PRODUCTION | Glucose-6-Phosphatase - genetics | Hypoglycemic Agents - metabolism | Diabetes Mellitus, Type 2 - genetics | Gluconeogenesis - drug effects | Diabetes Mellitus, Type 2 - metabolism | Hepatocytes - metabolism | Metformin - metabolism | AMP-Activated Protein Kinases | Hyperglycemia - genetics | Liver - drug effects | Protein-Serine-Threonine Kinases - metabolism | Liver - metabolism | Metformin - pharmacology | Mice, Inbred C57BL | Protein-Serine-Threonine Kinases - genetics | Glucose - genetics | Glucose - pharmacology | Glucose-6-Phosphatase - metabolism | Hypoglycemic Agents - pharmacology | Mice, Knockout | Hyperglycemia - metabolism | Phosphoenolpyruvate Carboxykinase (ATP) - genetics | Up-Regulation - drug effects | Animals | Gluconeogenesis - genetics | Glucose-6-Phosphatase - biosynthesis | Phosphoenolpyruvate Carboxykinase (ATP) - metabolism | Glucose - metabolism | Mice | Protein-Serine-Threonine Kinases - pharmacology | Type 2 diabetes | Control | Usage | Genetic aspects | Research | Metformin | Gene expression | Drug therapy | Health aspects | Gluconeogenesis | Up-Regulation | Glucose-6-Phosphatase | gluconeogenesis, animal models | Liver | Protein-Serine-Threonine Kinases | Glucose | Life Sciences | Hypoglycemic Agents | Phosphoenolpyruvate Carboxykinase (ATP) | Human health and pathology | Hyperglycemia | Hepatocytes | AMPK | Endocrinology and metabolism | Diabetes Mellitus, Type 2
Journal Article
Redox biology, ISSN 2213-2317, 2015, Volume 4, Issue C, pp. 184 - 192
Cancer formation is a complex and highly regulated multi-step process which is highly dependent of its environment, from the tissue to the patient. This... 
Mitochondria | Antioxidant | Mitophagy | Autophagy | ROS | Cancer | KAPPA-B ACTIVATION | OXIDATIVE STRESS | ACTIVATED PROTEIN-KINASE | METASTASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIAL AUTOPHAGY | HYPOXIA | FIBROBLASTS | METABOLISM | STROMA COEVOLUTION | GROWTH | Neoplasms - metabolism | AMP-Activated Protein Kinases - metabolism | Autophagy-Related Proteins | Reactive Oxygen Species - metabolism | Humans | Gene Expression Regulation, Neoplastic | Tumor Microenvironment | Antineoplastic Agents - therapeutic use | Intracellular Signaling Peptides and Proteins - metabolism | Autophagy-Related Protein-1 Homolog | Mitochondrial Degradation - genetics | Cysteine Endopeptidases - metabolism | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | Autophagy - genetics | Intracellular Signaling Peptides and Proteins - genetics | Kelch-Like ECH-Associated Protein 1 | Protein-Serine-Threonine Kinases - metabolism | Beclin-1 | Signal Transduction | Membrane Proteins - genetics | Protein-Serine-Threonine Kinases - genetics | Lymphatic Metastasis | Mitochondria - metabolism | Mitochondria - pathology | Cell Transformation, Neoplastic - metabolism | Apoptosis Regulatory Proteins - metabolism | Neoplasms - drug therapy | Cysteine Endopeptidases - genetics | Cell Transformation, Neoplastic - pathology | Neoplasms - pathology | AMP-Activated Protein Kinases - genetics
Journal Article
PloS one, ISSN 1932-6203, 2010, Volume 5, Issue 11, p. e15394
.... The serine/threonine kinase ULK1, like its yeast homologue Atg1, is a key initiator of autophagy that is negatively regulated by the mTOR kinase... 
COMPLEX | ACTIVATED PROTEIN-KINASE | METABOLISM | PHOSPHORYLATION | MACHINERY | BIOLOGY | INHIBITS CELL-GROWTH | INDUCTION | SACCHAROMYCES-CEREVISIAE | ATG13 | DEGENERATION | AMP-Activated Protein Kinases - metabolism | Phosphorylation | Immunoprecipitation | Humans | Multiprotein Complexes | Immunoblotting | Intracellular Signaling Peptides and Proteins - metabolism | Autophagy | Protein Subunits - metabolism | Autophagy-Related Protein-1 Homolog | Mechanistic Target of Rapamycin Complex 1 | Transfection | RNA Interference | HEK293 Cells | Regulatory-Associated Protein of mTOR | Binding Sites | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | 14-3-3 Proteins - genetics | Protein Subunits - genetics | Cell Line | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Mice, Knockout | 14-3-3 Proteins - metabolism | Proteins - genetics | Animals | Proteins - metabolism | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Protein Binding | Mice | TOR Serine-Threonine Kinases | Mutation | Adaptor Proteins, Signal Transducing - metabolism | AMP-Activated Protein Kinases - genetics | Microscopy, Fluorescence | TOR protein | Tuberous Sclerosis Complex 2 | Yeast | Homology | Kinases | Inactivation | Proteins | Cell growth | Cell cycle | Binding | Biodegradation | Deactivation | Threonine | Pharmacology | Metabolism | Mammals | Environmental stress | Medicine | 14-3-3 protein | Insects | Environmental degradation | Protein-serine/threonine kinase | Regulation | Phagocytosis | Cancer | Apoptosis
Journal Article
The EMBO Journal, ISSN 1460-2075, 2004, Volume 23, Issue 4, pp. 833 - 843
We recently demonstrated that the LKB1 tumour suppressor kinase, in complex with the pseudokinase STRAD and the scaffolding protein MO25, phosphorylates and activates AMP... 
cancer | cell polarity | PAR1/MARK kinase | Peutz–Jeghers syndrome | TOF–TOF mass spectrometry | diabetes | TOF-TOF mass spectrometry | Cell polarity | Diabetes | Peutz-Jeghers syndrome | Cancer | SERINE-THREONINE KINASE | PEUTZ-JEGHERS-SYNDROME | CYTOPLASMIC LOCALIZATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEPENDENT PROTEIN-KINASE | UPSTREAM KINASES | CELL BIOLOGY | GENE | SALT-INDUCIBLE KINASE | C-ELEGANS EMBRYOS | TUMOR-SUPPRESSOR | YEAST SNF1 | Amino Acid Sequence | Cell Line | Phosphorylation | Humans | Adaptor Proteins, Vesicular Transport - genetics | Protein-Serine-Threonine Kinases - genetics | Molecular Sequence Data | Multienzyme Complexes - metabolism | Substrate Specificity | Multienzyme Complexes - genetics | Adaptor Proteins, Vesicular Transport - metabolism | AMP-Activated Protein Kinases | Protein Subunits - metabolism | Peptides - metabolism | Protein Binding | Enzyme Activation | Mutation | Protein-Serine-Threonine Kinases - metabolism | Fibroblasts - metabolism | Protein Subunits - genetics | BRSK1 protein | MARK4 protein | QIK protein | SIK protein | MARK2 protein | MARK3 protein | LKB1 protein | NUAK2 protein | NUAK1 protein | phenformin | MARK1 protein | BRSK2 protein | MELK protein | QSK protein | PAR1 | MARK kinase | Biological Sciences | Naturvetenskap | Biokemi och molekylärbiologi | Biochemistry and Molecular Biology | Biologi | Natural Sciences
Journal Article
FEBS Letters, ISSN 0014-5793, 2001, Volume 496, Issue 1, pp. 44 - 48
The specificity of 4,5,6,7-tetrabromo-2-azabenzimidazole (TBB), an ATP/GTP competitive inhibitor of protein kinase casein kinase-2 (CK2... 
Casein kinase | Inhibitor | Casein kinase-2 | Protein phosphorylation | Protein kinase | nCK, native casein kinase | OA, okadaic acid | PRAK, p38-regulated/activated kinase | CSK, C-terminal Src kinase | AMPK, AMP-activated protein kinase | CHK, checkpoint kinase | JNK, c-Jun N-terminal kinase | MAPKAP, MAPK-activated protein kinase | p70S6K, p70 ribosomal protein S6 kinase | CK, casein kinase | SAPK, stress-activated protein kinase | PDK, 3-phosphoinositide-dependent kinase | ROCK, Rho-dependent protein kinase | CDK, cyclin-dependent kinase | G-CK, Golgi casein kinase | PKC, protein kinase C | MKK, MAPK kinase (also called MEK) | PKA, cAMP-dependent protein kinase | DRB, 1-(β-D-ribofuranosyl)-5,6-dichlorobenzimidazole | PHK, phosphorylase kinase | GSK3, glycogen synthase kinase 3 | PKB, protein kinase B (also called Akt) | rCK, recombinant casein kinase | ERK, extracellular signal-regulated kinase | HS1, hematopoietic lineage cell-specific protein 1 | MSK, mitogen- and stress-activated protein kinase | TBB, 4,5,6,7-tetrabromo-2-azabenzimidazole or 4,5,6,7-tetrabromobenzotriazole | MAPK, mitogen-activated protein kinase | SGK, serum- and glucocorticoid-induced kinase | CATALYTIC SUBUNIT | ZEA-MAYS | TYROSINE KINASE | CRYSTAL-STRUCTURE | COMPETITIVE INHIBITOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | protein phosphorylation | IMMUNOPHILIN FPR3 | SACCHAROMYCES-CEREVISIAE | protein kinase | CELL BIOLOGY | casein kinase | BIOPHYSICS | inhibitor | CELL-CYCLE | BETA-SUBUNIT | casein kinase-2 | MAMMARY-GLAND | Protein Kinases - metabolism | Jurkat Cells - cytology | Protein Kinases - drug effects | Casein Kinase II | Emodin - pharmacology | Jurkat Cells - metabolism | Humans | Enzyme Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - genetics | Substrate Specificity | Adenosine Triphosphate | Binding Sites - genetics | Binding, Competitive - drug effects | Triazoles - pharmacology | Triazoles - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Binding Sites - drug effects | Protein-Serine-Threonine Kinases - metabolism | Staurosporine - pharmacology | Amino Acid Substitution | Jurkat Cells - drug effects
Journal Article
Nature (London), ISSN 1476-4687, 2007, Volume 447, Issue 7147, pp. 1017 - 1020
AMP-activated protein kinase (AMPK, also known as SNF1A) has been primarily studied as a metabolic regulator that is activated in response to energy deprivation... 
CYTOKINESIS | MUTANTS | ROLES | DISC | MULTIDISCIPLINARY SCIENCES | LIGHT-CHAIN | MYOSIN-II | NONMUSCLE MYOSIN | Protein Kinases - metabolism | Cell Polarity | Protein-Serine-Threonine Kinases - deficiency | Phosphorylation | Protein Kinases - genetics | Mitosis | Humans | Multienzyme Complexes - metabolism | Male | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | AMP-Activated Protein Kinases | Multienzyme Complexes - deficiency | Female | Protein Kinases - deficiency | Protein-Serine-Threonine Kinases - metabolism | Cell Line | Drosophila melanogaster - cytology | Protein-Serine-Threonine Kinases - genetics | Multienzyme Complexes - genetics | Phenotype | Animals | Energy Metabolism | Drosophila Proteins - deficiency | Drosophila melanogaster - enzymology | Drosophila melanogaster - growth & development | Myosin Light Chains - metabolism | Drosophila Proteins - genetics | Physiological aspects | Usage | Cell physiology | Research | Protein kinases | Drosophila | Chemistry | Biochemistry | Cellular biology | Kinases | Proteins | Control | Deprivation | Polarity | Mathematical models | Activation energy | Drosophila Proteins | Multienzyme Complexes | Protein-Serine-Threonine Kinases | Biochemistry, Molecular Biology | Cellular Biology | Life Sciences | Protein Kinases | Myosin Light Chains | Drosophila melanogaster
Journal Article