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Journal of Biological Chemistry, ISSN 0021-9258, 03/2012, Volume 287, Issue 11, pp. 8001 - 8012
Doxorubicin, an anthracycline antibiotic, is widely used in cancer treatment. Doxorubicin produces genotoxic stress and p53 activation in both carcinoma and... 
SKELETAL-MUSCLE | OXIDATIVE-STRESS | INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | ANTHRACYCLINE-INDUCED CARDIOTOXICITY | INDUCED CARDIOMYOPATHY | GLUCOSE-UPTAKE | TUMOR-SUPPRESSOR P53 | NUCLEOTIDE EXCISION-REPAIR | TRANSGENIC MICE | Enzyme Activators - pharmacology | Sirtuin 1 - metabolism | AMP-Activated Protein Kinases - metabolism | Antibiotics, Antineoplastic - pharmacology | Antibiotics, Antineoplastic - adverse effects | Sirtuin 1 - genetics | Embryo, Mammalian - metabolism | Tumor Suppressor Protein p53 - genetics | Aminoimidazole Carboxamide - pharmacology | Dose-Response Relationship, Drug | Ribonucleosides - pharmacology | Cell Death - genetics | Gene Deletion | Cell Death - drug effects | Fibroblasts - metabolism | Embryo, Mammalian - pathology | AMP-Activated Protein Kinases - antagonists & inhibitors | Cells, Cultured | Tumor Suppressor Protein p53 - metabolism | Enzyme Activation - drug effects | Fibroblasts - pathology | Mice, Knockout | Myocytes, Cardiac - pathology | Animals | Aminoimidazole Carboxamide - analogs & derivatives | Myocytes, Cardiac - metabolism | Mice | DNA Damage | AMP-Activated Protein Kinases - genetics | Doxorubicin - adverse effects | Doxorubicin - pharmacology | Index Medicus | AMP Kinase | AMP-activated Kinase (AMPK) | Sirt1 | Oxidative Stress | Metabolism | p53
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PLoS ONE, ISSN 1932-6203, 02/2015, Volume 10, Issue 2, pp. e0117120 - e0117120
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