X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
chemistry, organic (98) 98
chemistry, multidisciplinary (54) 54
index medicus (40) 40
bioactive macrolides (37) 37
stereoselective-synthesis (33) 33
macrolides - chemistry (31) 31
amphidinolides (30) 30
molecular structure (30) 30
macrolides - chemical synthesis (29) 29
macrolides (28) 28
dinoflagellate (27) 27
stereoisomerism (26) 26
macrolide (25) 25
enantioselective synthesis (21) 21
aldehydes (19) 19
animals (18) 18
metathesis (18) 18
dinoflagellida - chemistry (17) 17
ring-closing metathesis (17) 17
stereochemistry (17) 17
fragment (16) 16
natural products (16) 16
structure elucidation (16) 16
total synthesis (16) 16
absolute stereochemistry (15) 15
asymmetric-synthesis (15) 15
natural-products (15) 15
synthesis (15) 15
analysis (14) 14
cyclization (14) 14
acid (13) 13
amphidinium sp (13) 13
amphidinolide (13) 13
catalysis (13) 13
cytotoxic agents amphidinolides (13) 13
derivatives (13) 13
organic-synthesis (13) 13
amphidinolide-a (12) 12
chemistry, medicinal (12) 12
letter (12) 12
organic compounds (12) 12
19-membered macrolide (11) 11
alcohols (11) 11
amphidinolide-x (11) 11
macrolides - isolation & purification (11) 11
magnetic resonance spectroscopy (11) 11
caribenolide-i structures (10) 10
moiety (10) 10
-amphidinolide-a (9) 9
enantioselective total-synthesis (9) 9
humans (9) 9
pharmacology & pharmacy (9) 9
segment (9) 9
amphidinolide-h (8) 8
cytotoxic (8) 8
efficient (8) 8
lactones - chemistry (8) 8
marine dinoflagellate (8) 8
aldol reaction (7) 7
aldol reactions (7) 7
amphidinolide b (7) 7
antineoplastic agents - chemical synthesis (7) 7
article (7) 7
biosynthesis (7) 7
cross-coupling reactions (7) 7
cytotoxic macrolide (7) 7
cytotoxic macrolides (7) 7
ketones (7) 7
lactones - chemical synthesis (7) 7
macrolides - pharmacology (7) 7
natural-product (7) 7
research (7) 7
stereoselective synthesis (7) 7
26-membered macrolide (6) 6
alkynes (6) 6
amphidinium (6) 6
amphidinolide c (6) 6
amphidinolide o (6) 6
biochemistry & molecular biology (6) 6
biological evaluation (6) 6
bridged bicyclo compounds, heterocyclic - chemical synthesis (6) 6
cell line, tumor (6) 6
chemical properties (6) 6
chemical synthesis (6) 6
chemistry (6) 6
configuration (6) 6
construction (6) 6
esters (6) 6
furans - chemistry (6) 6
macrolide antibiotics (6) 6
metabolites (6) 6
molecular conformation (6) 6
organic chemistry (6) 6
reagents (6) 6
ruthenium (6) 6
alkenes (5) 5
amphidinolide k (5) 5
amphidinolide-e (5) 5
amphidinolide-v (5) 5
amphidinolides c (5) 5
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Tetrahedron, ISSN 0040-4020, 10/2013, Volume 69, Issue 40, pp. 8632 - 8644
An allylic -epoxide prepared by Sharpless asymmetric epoxidation was transformed in nine steps and 41% overall yield to the cyclization precursor via a key one... 
Asymmetric dihydroxylation | Amphidinolide | Hydrostannylation | Natural products | Aerobic oxidation | PALLADIUM-CATALYZED ADDITION | ELATENYNE | RESOLUTION | COBALT(II) | CHEMISTRY, ORGANIC | ABSOLUTE STEREOCHEMISTRY | ALLENES | CYCLIZATION | MOLECULAR-OXYGEN
Journal Article
Tetrahedron, ISSN 0040-4020, 03/2018, Volume 74, Issue 13, pp. 1546 - 1554
The C18–C26 fragment of amphidinolide C congeners has been synthesized starting from methyl acetoacetate in 14 steps in >17.0% overall yield. The C20... 
Tetrahydrofuran | Asymmetric dihydroxylation | Amphidinolide C | Enyne | Intramolecular SN2 reaction | Sonogashira cross-coupling | Intramolecular S | 2 reaction
Journal Article
by Su, YX and Dai, WM
TETRAHEDRON, ISSN 0040-4020, 03/2018, Volume 74, Issue 13, pp. 1546 - 1554
Journal Article
Organic Letters, ISSN 1523-7060, 01/2007, Volume 9, Issue 2, pp. 307 - 310
A synthesis of 2-epi-amphidinolide E (1) has been accomplished via an unexpected and highly diastereoselective C(2) stereochemical inversion during the... 
(+)-AMPHIDINOLIDE-A | RING-CLOSING METATHESIS | NATURAL-PRODUCTS | ALKYLATION | CHEMISTRY, ORGANIC | BIOACTIVE MACROLIDES | AMPHIDINOLIDE-E | ALKYNE | STRUCTURE ELUCIDATION | MACROCYCLIZATION
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2009, Volume 50, Issue 46, pp. 6276 - 6279
The synthesis of the C1–C9 subunit of amphidinolides C and F is described. Key steps include tandem Sharpless asymmetric dihydroxylation-S 2 cyclization... 
Wittig reaction | Amphidinolide C and F | Wacker oxidation | Cytotoxic | Tandem dihydroxylation-S N2 | Tandem dihydroxylation-S | Tandem dihydroxylation-S(N)2 | DIHYDROXYLATION | TETRAHYDROFURANS | ALLYLIC ALCOHOLS | ASYMMETRIC EPOXIDATION | CHEMISTRY, ORGANIC | BIOACTIVE MACROLIDES | DINOFLAGELLATE AMPHIDINIUM SP
Journal Article
Synlett, ISSN 0936-5214, 3/2007, Volume 2007, Issue 4, pp. 0567 - 0570
Abstract The synthesis of the C19-C34 segment of amphidinolide C is described. The key steps include the Mioskowski’s Lewis acid catalyzed epoxide opening with... 
letter | Wittig reaction | Nozaki-Hiyama-Kishi coupling | Amphidinolide C | Cytotoxic | Ring-closing metathesis | ORGANIC-SYNTHESIS | ACID | CHEMISTRY, ORGANIC | amphidinolide C | BIOACTIVE MACROLIDES | MARINE | cytotoxic | ring-closing metathesis | METATHESIS
Journal Article
Russian Journal of Organic Chemistry, ISSN 1070-4280, 07/2015, Volume 51, Issue 7, pp. 920 - 930
A new simple and efficient procedure has been developed for the asymmetric synthesis of the C-7-C-14 building block for cytotoxic macrolactones, amphidinolides... 
ASYMMETRIC-SYNTHESIS | ENANTIOSELECTIVE SYNTHESIS | FORMAL SYNTHESIS | DINOFLAGELLATE | CHEMISTRY, ORGANIC | CYTOTOXIC AGENTS AMPHIDINOLIDES | ABSOLUTE STEREOCHEMISTRY | STEREOSELECTIVE-SYNTHESIS | BIOACTIVE MACROLIDES | PROPOSED STRUCTURE | MARINE NATURAL-PRODUCTS
Journal Article
Organic Letters, ISSN 1523-7060, 03/2014, Volume 16, Issue 6, pp. 1660 - 1663
Rhodium­(II) acetate catalyzes the denitrogenative transformation of 5-substituted and 4,5-disubstituted 1-sulfonyl-1,2,3-triazoles with pendent allyl and... 
AZAVINYL CARBENES | REARRANGEMENT | SULFONYL AZIDES | CATALYZED TRANSANNULATION | NATURAL-PRODUCTS | AMPHIDINOLIDES C | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | TERMINAL ALKYNES | INTRAMOLECULAR GENERATION | OXONIUM YLIDES
Journal Article
by Yang, Z and Jing, P and She, XG
CHINESE JOURNAL OF ORGANIC CHEMISTRY, ISSN 0253-2786, 02/2012, Volume 32, Issue 2, pp. 338 - 343
A stereoselective synthesis of C(13)-C(23) subunit of iriomoteolide-1b has been achieved in 13% yield over 13 steps from the known diol, exploiting the... 
asymmetric aldol reaction | Julia-Kocienski olefination | NATURAL-PRODUCT | AMPHIDINOLIDES | ENANTIOSELECTIVE SYNTHESIS | iriomoteolide-1b | stereoselective synthesis | CHEMISTRY, ORGANIC | C-13-C23 FRAGMENT | MACROLIDES
Journal Article
by Bi, HP and Chen, WW and Liang, YM and Li, CJ
ORGANIC LETTERS, ISSN 1523-7060, 08/2009, Volume 11, Issue 15, pp. 3246 - 3249
A novel iron-catalyzed intermolecular decarboxylative Csp(3)-Csp(2) coupling reaction using proline derivatives as starting materials is developed. In this... 
ARYL GRIGNARD-REAGENTS | ORGANIC-SYNTHESIS | OXIDATIVE DECARBOXYLATION | NITROGEN ATOM | CHEMISTRY, ORGANIC | ALPHA-AMINO-ACIDS | AMPHIDINOLIDE-X | REARRANGEMENT REACTIONS | C-H BONDS | BEARING BETA-HYDROGENS | ALKYL-HALIDES
Journal Article
Tetrahedron, ISSN 0040-4020, 2004, Volume 60, Issue 52, pp. 12191 - 12199
Lytophilippines A–C, new chloro-containing macrolactones, were isolated from the Red Sea hydroid and their structures were elucidated by IR, UV, MS, H and C... 
Lytophilippines A–C | Lytocarpus philippinus | Red Sea hydroid | Macrolactones | Lytophilippines A-C | GLYCOSIDES | ANTIBIOTICS | ACID | AMPHIDINOLIDES | STEREOCHEMISTRY | CHEMISTRY, ORGANIC | lytophilippines A-C | MACROLIDES | macrolactones | MARINE NATURAL-PRODUCT | SPONGE | LICHENS | ESTERS
Journal Article
Tetrahedron, ISSN 0040-4020, 2003, Volume 59, Issue 10, pp. 1613 - 1625
Two of each diastereomers of the C-1-C-10 and C-17-C-29 segments of amphidinolide C (1) were synthesized. Comparing the H NMR chemical shifts of its MTPA... 
amphidinolide C | α-methoxy-α-trifluoromethylphenylacetyl | acetonide | Amphidinolide C | Acetonide | SECONDARY ALCOHOLS | OXIDATION | alpha-methoxy-alpha-trifluoromethylphenylacetyl | CHEMISTRY, ORGANIC | CONFIGURATIONS
Journal Article
Helvetica Chimica Acta, ISSN 0018-019X, 07/2019, Volume 102, Issue 7, p. n/a
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 1998, Volume 39, Issue 42, pp. 7775 - 7778
Stereoselective synthesis of the entire (16S, 18S, 21R, 22S, 23R, 25R)-C-15-C-26 segment 1 of amphidinolides G and H has been achieved for the first time... 
antitumor compounds | macrolides | aldol reactions | amphidinolides | ENANTIOSELECTIVE SYNTHESIS | STEREOSELECTIVE REDUCTION | DINOFLAGELLATE | CHEMISTRY, ORGANIC | AMPHIDINIUM SP
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 10/2018, Volume 57, Issue 41, pp. 13575 - 13581
Journal Article
Tetrahedron, ISSN 0040-4020, 08/2016, Volume 72, Issue 32, pp. 4962 - 4967
Base- and acid-catalyzed intramolecular oxy-Michael reactions are reported. Three ε-hydroxy α,β-unsaturated ketones , , and and one ester were cyclized in 5-... 
THF ring | Catalytic reaction | Facial selectivity | Stereochemistry | Oxy-Michael reaction | ASYMMETRIC-SYNTHESIS | FORMAL SYNTHESIS | NATURAL-PRODUCTS | NUCLEOSIDES | CHEMISTRY, ORGANIC | ABSOLUTE STEREOCHEMISTRY | AMPHIDINOLIDE-C | CONSTRUCTION | FRAGMENT | STEREOSELECTIVE-SYNTHESIS | CYCLIZATION | Ketones | Precursors | Tetrahedrons | Tetrahydrofuran | Esters | Isomers | Bearing
Journal Article
Marine Biotechnology, ISSN 1436-2228, 6/2018, Volume 20, Issue 3, pp. 343 - 352
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.