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ampkα (67) 67
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Journal of Functional Foods, ISSN 1756-4646, 08/2019, Volume 59, pp. 8 - 15
Chicoric acid is a naturally-occurring dicaffeoyl ester often found in chicory. Based on previous studies chicoric acid ameliorated insulin resistance in human... 
Glucose uptake | AMPKα | Chicoric acid | Akt | C2C12 myotubes | 3T3-L1 ADIPOCYTES | FOOD SCIENCE & TECHNOLOGY | RELEASE | ADIPOGENESIS | SIRT1 | SKELETAL-MUSCLE | IN-VITRO | NUTRITION & DIETETICS | AMPK alpha | INSULIN-RESISTANCE | EXTRACT
Journal Article
Journal of Basic and Clinical Physiology and Pharmacology, ISSN 0792-6855, 02/2014, Volume 25, Issue 1, pp. 109 - 115
Methylglyoxal is a major precursor in the formation of advanced glycation end products and is associated with the pathogenesis of diabetes-related vascular... 
methylglyoxal | eNOS | AMP-activated protein kinase α (AMPKα) | endothelium-dependent relaxation
Journal Article
Biochemical Journal, ISSN 0264-6021, 03/2013, Volume 450, Issue 2, pp. 351 - 363
ERK1/2 (extracellular-signal-regulated kinase 1/2) and their substrates RSKs (p90 ribosomal S6 kinases) phosphorylate different transcription factors,... 
Endothelin | α1-adrenergic receptor | P90 ribosomal S6 kinase (p90 RSK) | Transcriptomics | Cardiomyocyte | Mitogen-activated protein kinase (MAPK) | SNK, Student–Newman–Keuls | Lif, leukaemia inhibitory factor | Olr1, oxidized low-density lipoprotein (lectin-like) receptor 1 | Dusp, dual-specificity phosphatase | MNK, MAPK-interacting protein kinase | CREB, cAMP-response-element-binding protein | PKB, protein kinase B | ERK1 | RSK, ribosomal S6 kinase | transcriptomics | PE, phenylephrine | p90 ribosomal S6 kinase (p90 RSK) | AR, adrenergic receptor | Egr, early growth response | BH-MTC, Benjamini and Hochberg multiple testing correction | mitogen-activated protein kinase (MAPK) | ET-1, endothelin-1 | β, glycogen synthase kinase 3α | AMPKα, AMP-activated protein kinase α | Areg, amphiregulin | MKK, MAPK kinase | Rgs2, regulator of G-protein signalling 2, 24 kDa | 2, extracellular-signal-regulated kinase 1 | Atf3, activating transcription factor 3 | Klf, Krüppel-like factor | endothelin | GSK3α | Gapdh, glyceraldehyde 3-phosphate dehydrogenase | Plk2, polo-like kinase 2 | Nr4a, nuclear receptor subfamily 4, group A | Sik1, salt-inducible kinase 1 | cardiomyocyte | FDR, false discovery rate | Fosb, FBJ murine osteosarcoma viral oncogene homologue B | MSK, mitogen- and stress-activated protein kinase | IL11, interleukin 11 | NPE, nuclear protein-enriched | MAPK, mitogen-activated protein kinase | Ptgs2, prostaglandin-endoperoxide synthase 2, qPCR, quantitative PCR | Has, hyaluronan synthase
Journal Article
Molecular Metabolism, ISSN 2212-8778, 2014, Volume 3, Issue 2, pp. 177 - 190
Abstract Pairing the selective estrogen receptor modulator bazedoxifene (BZA) with estrogen as a tissue-selective estrogen complex (TSEC) is a novel menopausal... 
Endocrinology & Metabolism | Type 2 diabetes | Insulin resistance | Tissue-selective estrogen complexes | Metabolic syndrome | Bazedoxifene | Menopause | Bazedoxiiene | ENDOCRINOLOGY & METABOLISM | Tissue selective estrogen complexes | Life Sciences | Food and Nutrition | Neurons and Cognition
Journal Article
Journal Article
Acta Pharmaceutica Sinica B, ISSN 2211-3835, 2015, Volume 5, Issue 2, pp. 145 - 150
microRNAs (miRNAs or miRs) are small non-coding RNAs that are involved in post-transcriptional regulation of their target genes in a sequence-specific manner.... 
Nuclear receptors | MicroRNAs | Lipid metabolism | microRNAS | CANCER-CELLS | Lipid merabolism | DOWN-REGULATION | LIVER-DISEASE | FARNESOID X RECEPTOR | IN-VIVO | GENE-EXPRESSION | PPAR-GAMMA | PHARMACOLOGY & PHARMACY | CHOLESTEROL HOMEOSTASIS | HEPATIC STEATOSIS | microRNAs | HMGCR, 3-hydroxy-3-methylglutaryl-coenzyme A reductase | CRAT, carnitine O-acetyltransferase | SIRT6, sirtuin 6 | Ago2, argonaute 2 | ERRγ, estrogen-related receptor gamma | LNPs, lipid-based nanoparticles | LIPE, lipase hormone-sensitive | MHV68, murine γ-herpesvirus 68 | CYP26, cytochrome P450 family 26 | LNA, locked nucleic acids | CPT1A, carnitine palmitoyltransferase 1A | pri-miRNAs, primary-miRNAs | PDCD4, programmed cell death 4 | BDL, bile-duct ligation | AMPKα, AMP-activated protein kinase α | FASN, fatty acid synthase | GABPA, GA binding protein transcription factor alpha subunit | SIRT1, sirtuin 1 | FGF21, fibroblast growth factor 21 | LPS, lipopolysaccharide | enoyl-CoA hydratase trifunctional protein, beta subunit | IGFBP3, insulin-like growth factor binding protein 3 | ATP8B1, aminophospholipid transporter, class I, type 8B, member 1 | ABCA1, adenosine triphosphate-binding cassette transporter A1 | HCV, hepatitis C virus | HNE, 4-hydroxynonenal | Review | HMGCS1, 3-hydroxy-3-methylglutaryl-coenzyme A synthase 1 | RTL1, retrotransposon-like 1 | TG, triglyceride | PNA, peptide nucleic acid | PLIN1, perilipin 1 | SHP, small heterodimer partner | CYP3A4, cytochrome P450 family 3 subfamily A polypeptide 4 | HADHB, hydroxyacyl-CoA dehydrogenase | IGF1R, insulin-like growth factor 1 receptor | NRs, nuclear receptors | PNPLA2, patatin-like phospholipase domain containing 2 | REV-ERBα, transcriptional repressor nuclear receptor subfamily 1 group D member 1 | TLR4, toll-like receptor 4 | FABP7, fatty acid-binding protein 7 | MTTP, microsomal TG transfer protein | PGC-1, peroxisone proliferator-activated receptor gamma coactivator | MED13, mediator complex subunit 13 | FGFR1, fibroblast growth factor receptor 1 | FXR, farnesoid X receptor | 3-ketoacyl-CoA thiolase | ApoA1, apolipoprotein A1 | INSIG1, insulin induced gene 1 | RXRα, retinoid X receptor alpha | NR1D1 | PPARγ, peroxisone proliferator-activated receptor gamma | ABCG1, adenosine triphosphate-binding cassette transporter G1 | PCK1, phosphoenolpyruvate carboxykinase 1 | HCC, hepatocellular carcinoma | miRNAs or miRs, microRNAs | GPC6, glypican 6 | pre-miRNAs, precursor-miRNAs
Journal Article
Journal Article
Experimental Neurology, ISSN 0014-4886, 02/2017, Volume 288, pp. 85 - 93
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 11/2016, Volume 17, Issue 11, p. 1865
The aim of this study was to investigate the mechanisms underlying the inhibitory effects of berberine (BBR) on olanzapine (OLZ)-induced adipogenesis in a... 
3T3-L1 cells | Berberine | SREBPs | AMPKα | Olanzapine | Adipogenesis | ACTIVATED PROTEIN-KINASE | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | RATS | LIPOGENIC GENE-EXPRESSION | CHEMISTRY, MULTIDISCIPLINARY | berberine | ATYPICAL ANTIPSYCHOTIC-DRUGS | CHOLESTEROL-METABOLISM | olanzapine | adipogenesis | AMPK alpha | FATTY-ACID | LIVER | WEIGHT-GAIN | MODULATION | Fatty Acid Synthase, Type I - genetics | AMP-Activated Protein Kinases - metabolism | Triglycerides - biosynthesis | Adipogenesis - drug effects | Adipocytes - cytology | Adipocytes - drug effects | PPAR gamma - metabolism | Triglycerides - antagonists & inhibitors | Lipid Metabolism - genetics | Cell Differentiation | Sterol Regulatory Element Binding Protein 2 - genetics | Benzodiazepines - antagonists & inhibitors | Phosphorylation - drug effects | Sterol Regulatory Element Binding Protein 2 - metabolism | Adipogenesis - genetics | Sterol Regulatory Element Binding Protein 1 - metabolism | PPAR gamma - genetics | Receptors, LDL - genetics | Benzodiazepines - pharmacology | Signal Transduction | Gene Expression Regulation | Receptors, LDL - metabolism | 3T3-L1 Cells | Hypolipidemic Agents - pharmacology | Fatty Acid Synthase, Type I - metabolism | Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent - genetics | Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent - metabolism | Berberine - pharmacology | Animals | Antipsychotic Agents - antagonists & inhibitors | Sterol Regulatory Element Binding Protein 1 - genetics | Adipocytes - metabolism | Lipid Metabolism - drug effects | Mice | Antipsychotic Agents - pharmacology | Cholesterol - biosynthesis | AMP-Activated Protein Kinases - genetics
Journal Article
Cellular Signalling, ISSN 0898-6568, 04/2014, Volume 26, Issue 4, pp. 825 - 832
Journal Article
Journal of Medicinal Food, ISSN 1096-620X, 07/2017, Volume 20, Issue 7, pp. 646 - 652
Journal Article
Journal Article