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Journal Article
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 04/2007, Volume 150, Issue 7, pp. 951 - 960
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 01/2007, Volume 150, Issue 2, pp. 186 - 191
Background and purpose: Two compounds, URB602 and URB754, have been reported in the literature to be selective inhibitors of monoacylglycerol lipase, although... 
monoacylglycerol lipase | URB597 | 2‐acylglycerol | fatty acid amide hydrolase | anandamide | URB602 | URB754 | Monoacylglycerol lipase | Fatty acid amide hydrolase | 2-acylglycerol | Anandamide | 2-ARACHIDONOYLGLYCEROL | ASSAY | ANALOGS | TISSUE | INACTIVATION | INHIBITION | ACID AMIDE HYDROLASE | PHARMACOLOGY & PHARMACY | RECEPTORS | BRAIN | Recombinant Proteins - antagonists & inhibitors | Aniline Compounds - pharmacology | Rats, Wistar | Monoacylglycerol Lipases - antagonists & inhibitors | Cerebellum - metabolism | Humans | Cells, Cultured | Rats | Amidohydrolases - antagonists & inhibitors | Male | Glycerides - metabolism | Polyunsaturated Alkamides - metabolism | Hydrolysis | Membranes - metabolism | Arachidonic Acids - metabolism | Animals | Biphenyl Compounds - pharmacology | Benzoxazines - pharmacology | Cell Line, Tumor | Cytosol - metabolism | Mice | In Vitro Techniques | Endocannabinoids | Research Papers | Aniline Compounds/pharmacology | Monoacylglycerol Lipases/antagonists & inhibitors | Recombinant Proteins/antagonists & inhibitors | Rats; Wistar | Cells; Cultured | Membranes/metabolism | Amidohydrolases/antagonists & inhibitors | Polyunsaturated Alkamides/metabolism | Benzoxazines/pharmacology | Arachidonic Acids/metabolism | Biphenyl Compounds/pharmacology | Cerebellum/metabolism | Cell Line; Tumor | Glycerides/metabolism | Cytosol/metabolism
Journal Article
Pain, ISSN 0304-3959, 09/2017, Volume 158, Issue 9, pp. 1711 - 1722
Chronic pain and hyperalgesia, as well as pain resulting from episodes of vaso-occlusion, are characteristic features of sickle cell disease (SCD) and are... 
URB597 | Cannabinoid | Murine | FAAH inhibitor | Hyperalgesia | IN-SITU HYBRIDIZATION | ENDOGENOUS CANNABINOID ANANDAMIDE | BONE CANCER PAIN | NEUROBLASTOMA-CELLS | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | CLINICAL NEUROLOGY | MURINE MODEL | CALCIUM-CHANNELS | PERIPHERAL MECHANISMS | MECHANICAL HYPERALGESIA | ANESTHESIOLOGY | PRIMARY SENSORY NEURONS | Anemia, Sickle Cell - pathology | Endocannabinoids - metabolism | Pain Threshold - physiology | Pyrazoles - therapeutic use | Hydrolysis - drug effects | Humans | Male | Receptor, Cannabinoid, CB2 - antagonists & inhibitors | Receptor, Cannabinoid, CB2 - genetics | Arachidonic Acids - metabolism | Benzamides - therapeutic use | Nerve Fibers, Unmyelinated - drug effects | Pain Threshold - drug effects | Morpholines - therapeutic use | Disease Models, Animal | Hemoglobins - metabolism | Hemoglobins - genetics | Mice, Transgenic | Polyunsaturated Alkamides - metabolism | Enzyme Inhibitors - therapeutic use | Hyperalgesia - physiopathology | Evoked Potentials - drug effects | Nerve Fibers, Unmyelinated - pathology | Receptor, Cannabinoid, CB2 - metabolism | Animals | Evoked Potentials - genetics | Hyperalgesia - drug therapy | Nerve Fibers, Unmyelinated - metabolism | Anemia, Sickle Cell - metabolism | Indoles - therapeutic use | Mice | Nociceptors - metabolism | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Carbamates - therapeutic use | Nociceptors - drug effects | Anemia, Sickle Cell - genetics
Journal Article
Neuropharmacology, ISSN 0028-3908, 03/2017, Volume 114, pp. 156 - 167
Although opioids are highly efficacious analgesics, their abuse potential and other untoward side effects diminish their therapeutic utility. The addition of... 
Self-administration | 2-arachidonyl glycerol (2-AG) | Pain | Fatty acid amide hydrolase (FAAH) | Monoacylglycerol lipase (MAGL) | Morphine | Anandamide (AEA) | Cannabinoid | Heroin | RAT | MONOACYLGLYCEROL LIPASE | CB2 RECEPTOR | NEUROPATHIC PAIN MODEL | NEUROSCIENCES | PERIPHERAL CANNABINOID RECEPTORS | NUCLEUS-ACCUMBENS | ACID AMIDE HYDROLASE | OPIOID WITHDRAWAL SYMPTOMS | PHARMACOLOGY & PHARMACY | MODULATION | CHRONIC NONCANCER PAIN | Endocannabinoids - metabolism | Inflammation - chemically induced | Arachidonic Acid - metabolism | Sciatic Nerve - injuries | Receptor, Cannabinoid, CB2 - physiology | Male | Carbamates - administration & dosage | Receptor, Cannabinoid, CB2 - genetics | Receptor, Cannabinoid, CB1 - physiology | Dose-Response Relationship, Drug | Inflammation - complications | Arachidonic Acids - metabolism | Self Administration | Neuralgia - prevention & control | Neuralgia - etiology | Heroin - administration & dosage | Mice, Inbred C57BL | Analgesics - administration & dosage | Hyperalgesia - prevention & control | Glycerides - metabolism | Polyunsaturated Alkamides - metabolism | Drug-Seeking Behavior - drug effects | Mice, Knockout | Hydrolysis | Animals | Receptor, Cannabinoid, CB1 - genetics | Analgesics, Opioid - administration & dosage | Mice | Carrageenan | Morphine - administration & dosage | Acetamides - administration & dosage | Drug abuse | Care and treatment | Carrageenin | Glycerol | Lipase | Fatty acids | Glycerin | Liability (Law) | Analysis | Physiological aspects | Index Medicus | pain | heroin | fatty acid amide hydrolase (FAAH) | self-administration | anandamide (AEA) | cannabinoid | monoacylglycerol lipase (MAGL) | morphine
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2004, Volume 492, Issue 1, pp. 1 - 11
Journal Article
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 05/2019, Volume 9, Issue 1, pp. 7622 - 12
The large pore ion channel pannexin-1 (Panx1) has been reported to play a role in the cellular uptake and release of anandamide (AEA) in the hippocampus. It is... 
LOCALIZATION | PALMITOYLETHANOLAMIDE | ACID | INHIBITION | PROTEIN | EXPERIMENTAL COLITIS | MEMBRANE | ENDOCANNABINOIDS | MULTIDISCIPLINARY SCIENCES | GASTROINTESTINAL MOTILITY | MICE | Hydrolysis | Mefloquine | Colon cancer | 2-Arachidonylglycerol | Palmitoylethanolamide | Colorectal cancer | Tritium | mRNA | Prostate cancer | Hippocampus | Neuroblastoma cells | Anandamide
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 10/2001, Volume 134, Issue 4, pp. 845 - 852
Journal Article