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2009, ISBN 1402095635, ix, 125
In 1971, J. Folkman published in the "New England Journal of Medicine" a hypothesis that tumor growth is angiogenesis-dependent. Folkman introduced the concept... 
Neovascularization | Blood-vessels | Growth | Neovascularization inhibitors | Tumors | Clinical & internal medicine | Treatment | Pathology | History of Science | Biomedicine | Cancer Research | Oncology | Biomedicine general | Cell Biology
Book
CA: A Cancer Journal for Clinicians, ISSN 0007-9235, 07/2010, Volume 60, Issue 4, pp. 222 - 243
Angiogenesis has become an attractive target for drug therapy because of its key role in tumor growth. An extensive array of compounds is currently in... 
CELL LUNG-CANCER | TYROSINE KINASE INHIBITORS | PHASE-III TRIAL | FARNESYL-PROTEIN TRANSFERASE | HYPOXIA-INDUCIBLE FACTOR | SUPPRESSES TUMOR-GROWTH | ONCOLOGY | ENDOTHELIAL-GROWTH-FACTOR | FACTOR EXPRESSION | VASCULAR-PERMEABILITY FACTOR | METASTATIC COLORECTAL-CANCER | Neoplasms - metabolism | Nucleic Acid Synthesis Inhibitors - pharmacology | Humans | Receptor Protein-Tyrosine Kinases - physiology | Antibodies, Monoclonal - therapeutic use | Receptors, Notch - antagonists & inhibitors | Protein Binding - drug effects | Angiogenesis Inhibitors - therapeutic use | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Neovascularization, Pathologic - prevention & control | Farnesyltranstransferase - antagonists & inhibitors | Thioredoxins - antagonists & inhibitors | Nucleic Acid Synthesis Inhibitors - therapeutic use | Basic Helix-Loop-Helix Transcription Factors - physiology | Antibodies, Monoclonal - pharmacology | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Angiogenesis Inhibitors - pharmacology | Receptors, Notch - physiology | Neoplasms - blood supply | Basic Helix-Loop-Helix Transcription Factors - antagonists & inhibitors | Neoplasms - drug therapy | Signal Transduction - drug effects | Cell Transformation, Neoplastic | HSP90 Heat-Shock Proteins - antagonists & inhibitors | Intracellular Signaling Peptides and Proteins - physiology | Complications and side effects | Care and treatment | Ligands (Biochemistry) | Physiological aspects | Development and progression | Dosage and administration | Angiogenesis inhibitors | Neovascularization | Identification and classification | Growth factors | Cancer | Angiogenesis | Pharmacology | FDA approval | Drug therapy | Kinases | Tumors | hypoxia inducible factor (HIF) | kinase inhibitors | growth factors | angiogenesis inhibitors | VEGF | anti-angiogenesis
Journal Article
British Journal of Haematology, ISSN 0007-1048, 12/2015, Volume 171, Issue 5, pp. 798 - 812
Journal Article
2010, Recent results in cancer research, ISBN 9783540782803, Volume 180., xiv, 231
All aspects from the bench to the bedside are considered in this examination of the latest developments in angiogenesis inhibition in cancer. The authors pay... 
Neovascularization inhibitors | Clinical & internal medicine | Chemotherapy | Therapeutic use | Cancer | Oncology | Cancer Research | Medicine & Public Health | Hematology
Book
Clinical Cancer Research, ISSN 1078-0432, 03/2009, Volume 15, Issue 5, pp. 1612 - 1622
Purpose: Comparison of the antiangiogenic/vascular properties of the oral mammalian target of rapamycin (mTOR) inhibitor RAD001 (everolimus) and the vascular... 
pharmacokinetics | DCE-MRI | RAD001 | angiogenesis | PTK/ZK | MAMMALIAN TARGET | FACTOR-RECEPTOR | RAPAMYCIN | ANGIOGENESIS | ONCOLOGY | IN-VIVO | MAGNETIC-RESONANCE | CELL-PROLIFERATION | OVARIAN-CANCER | TUMOR VASCULATURE | ENDOTHELIAL GROWTH-FACTOR | Protein Kinases - metabolism | Phthalazines - pharmacokinetics | Humans | Protein Kinases - chemistry | Pyridines - pharmacokinetics | Transplantation, Heterologous | Vascular Endothelial Growth Factor A - metabolism | Immunoenzyme Techniques | Tissue Distribution | Rats, Inbred BN | Receptors, Vascular Endothelial Growth Factor - metabolism | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Female | Receptor, TIE-2 - metabolism | Everolimus | Rats, Inbred WF | Protein Kinase Inhibitors - pharmacokinetics | Sirolimus - analogs & derivatives | Mice, Inbred C57BL | Angiogenesis Inhibitors - pharmacology | Rats | Angiogenesis Inhibitors - pharmacokinetics | Sirolimus - pharmacokinetics | Sirolimus - pharmacology | Cell Movement - drug effects | Magnetic Resonance Imaging | Phthalazines - pharmacology | Animals | Neovascularization, Pathologic - drug therapy | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | TOR Serine-Threonine Kinases | Neoplasms, Experimental - metabolism | Neoplasms, Experimental - drug therapy | Neoplasms, Experimental - blood supply
Journal Article