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Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, ISSN 1735-5338, 02/2019, Volume 21, Issue 7, pp. 112 - 122
Background and Aim: The eNOS gene that is responsible for the production of nitric oxide and angiostatin is an inhibitor of angiogenesis. The aim of present... 
eNOS | Endurance training | Angiostatin
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 09/2018, Volume 72, Issue 13, pp. B230 - B230
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, pp. e32388 - e32388
Background: We have previously reported the role of anti-angiogenic factors in inducing the transition from compensatory cardiac hypertrophy to heart failure... 
APOPTOSIS | OXIDATIVE STRESS | ISCHEMIC CARDIOMYOPATHY | ANGIOGENESIS | MATRIX-METALLOPROTEINASE | MULTIDISCIPLINARY SCIENCES | CARDIOVASCULAR-DISEASE | DEATH | AUTOPHAGY | FISSION | MAMMALIAN-CELLS | Immunohistochemistry | Mitochondria, Heart - metabolism | Gene Expression - drug effects | Apoptosis - drug effects | Vascular Endothelial Growth Factor A - metabolism | Mitochondria, Heart - drug effects | Vascular Endothelial Growth Factor A - genetics | Electron Transport Complex IV - metabolism | Heart Failure - prevention & control | Matrix Metalloproteinase 9 - metabolism | Matrix Metalloproteinase 9 - genetics | Myocardium - metabolism | Tissue Inhibitor of Metalloproteinase-3 - metabolism | Angiostatins - metabolism | Heart Failure - diagnostic imaging | Heart Failure - etiology | Quinazolinones - pharmacology | Tissue Inhibitor of Metalloproteinase-3 - genetics | Heart - physiopathology | Echocardiography | Endostatins - metabolism | Matrix Metalloproteinase 2 - metabolism | Hypertrophy, Left Ventricular - prevention & control | Mice, Inbred C57BL | Angiostatins - genetics | Myocardium - pathology | Reverse Transcriptase Polymerase Chain Reaction | Constriction, Pathologic - complications | Pressure | Aorta - pathology | Endostatins - genetics | Matrix Metalloproteinase 2 - genetics | Animals | Heart - drug effects | Mice | Hypertrophy, Left Ventricular - physiopathology | Hypertrophy, Left Ventricular - diagnostic imaging | Heart failure | Heart | Heart enlargement | Health aspects | Vascular endothelial growth factor | Oxidative stress | Pathogenesis | Cardiomyopathy | Endostatin | Smooth muscle | Cardiovascular disease | Tissue inhibitor of metalloproteinase 3 | Polyamines | Autophagy | Angiogenesis | Mitochondria | Ischemia | Rodents | Extracellular matrix | Aorta | Growth factors | Heart diseases | Failure | Medical research | Immunoglobulins | Mortality | Organelles | Gelatinase B | Gelatinase A | Studies | Peroxisomes | Ostomy | Banding | Inhibitors | Coronary vessels | Fibrosis | Diabetes | Angiostatin | Phagocytosis | Hypertrophy | Apoptosis | Index Medicus
Journal Article
SEMINARS IN ONCOLOGY, ISSN 0093-7754, 12/2002, Volume 29, Issue 6, pp. 15 - 18
Journal Article
British Journal of Cancer, ISSN 0007-0920, 11/2011, Volume 105, Issue 11, pp. 1750 - 1758
BACKGROUND: The intake of dietary fatty acids is highly correlated with the risk of various cancers. Linoleic acid (LA) is the most abundant polyunsaturated... 
linoleic acid | angiostatin | invasion | gastric carcinoma | plasminogen activator inhibitor 1 | CANCER-CELLS | TGF-BETA | METASTASIS | PROTEIN | ENDOTHELIAL-CELL MIGRATION | IN-VITRO | ONCOLOGY | GASTRIC-CARCINOMA | GROWTH | EXPRESSION | RNA-Binding Proteins - genetics | Angiostatins - antagonists & inhibitors | Human Umbilical Vein Endothelial Cells - metabolism | Apoptosis - drug effects | Humans | Stomach Neoplasms - metabolism | Stomach Neoplasms - blood supply | Plasminogen Activator Inhibitor 1 - metabolism | RNA Interference | Neoplasm Invasiveness - pathology | Female | Angiostatins - metabolism | Linoleic Acid - pharmacology | Plasminogen Activator Inhibitor 1 - genetics | RNA-Binding Proteins - blood | Tumor Cells, Cultured | Microarray Analysis - methods | Stomach Neoplasms - genetics | Cell Survival - drug effects | Human Umbilical Vein Endothelial Cells - drug effects | RNA, Messenger - genetics | Angiostatins - genetics | Angiostatins - blood | Gene Expression Profiling - methods | Neovascularization, Pathologic - chemically induced | Disease Progression | Plasminogen Activator Inhibitor 1 - blood | Animals | Mice, Nude | Neovascularization, Pathologic - genetics | Mice | Neovascularization, Pathologic - metabolism | Neoplasm Invasiveness - genetics | RNA-Binding Proteins - metabolism | Index Medicus | Molecular Diagnostics
Journal Article
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 6/2013, Volume 33, Issue 6, pp. 1339 - 1349
Journal Article
Journal Article
Journal of Industrial Microbiology & Biotechnology, ISSN 1367-5435, 2/2007, Volume 34, Issue 2, pp. 117 - 122
A high-density cell culture method to produce human angiostatin has been successfully established by constitutive expression of the protein in Pichia pastoris.... 
Biochemistry, general | Biotechnology | Chemistry | Genetic Engineering | Microbiology | Microbial Genetics and Genomics | Bioactivity | Pichia pastoris | Angiostatin | Constitutive expression | Bioinformatics | High-density cell culture | angiostatin | high-density cell culture | ANGIOGENESIS | CANCER | STRATEGIES | HETEROLOGOUS PROTEIN-PRODUCTION | YEAST | RECOMBINANT HUMAN ANGIOSTATIN | bioactivity | GENE | PROMOTERS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GROWTH | constitutive expression | INHIBITOR | Humans | Melanoma, Experimental - drug therapy | Male | Recombinant Proteins - biosynthesis | Biotechnology - methods | Pichia - metabolism | Culture Media | Angiogenesis Inhibitors - therapeutic use | Gene Expression Regulation, Fungal | Genetic Engineering - methods | Promoter Regions, Genetic | Angiogenesis Inhibitors - genetics | Angiostatins - therapeutic use | Mice, Inbred C57BL | Angiostatins - genetics | Angiogenesis Inhibitors - pharmacology | Treatment Outcome | Glyceraldehyde-3-Phosphate Dehydrogenases - genetics | Chick Embryo | Animals | Angiogenesis Inhibitors - biosynthesis | Bioreactors | Mycology - methods | Angiostatins - biosynthesis | Angiostatins - pharmacology | Pichia - genetics | Cell Line, Tumor | Mice | Glyceraldehyde-3-Phosphate Dehydrogenases - metabolism | Pichia - growth & development | Index Medicus
Journal Article
Journal Article
Human Gene Therapy, ISSN 1043-0342, 01/2017, Volume 28, Issue 1, pp. 99 - 111
Journal Article
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 08/2017, Volume 259, pp. e181 - e182
Journal Article
Cancer Research, ISSN 0008-5472, 07/1999, Volume 59, Issue 14, pp. 3374 - 3378
The family of vascular endothelial growth factor (VEGF) proteins include potent and specific mitogens for vascular endothelial cells that function in the... 
INHIBITION | METASTASIS | THERAPY | ANGIOGENESIS | ONCOLOGY | ANGIOSTATIN | FACTOR-NEUTRALIZING ANTIBODY | TUMOR-GROWTH
Journal Article
International Journal of Cancer, ISSN 0020-7136, 08/2005, Volume 116, Issue 1, pp. 52 - 61
Inhibitors of matrix metalloproteinases (MMPs) were developed as anticancer agents based on the observation that MMPs facilitate local tumor spread and... 
angiostatin | matrix metalloproteinase inhibitor | CT26 | angiogenesis | Angiogenesis | Matrix metalloproteinase inhibitor | Angiostatin
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 05/2003, Volume 63, Issue 9, pp. 2020 - 2023
A novel disintegrin, obtustatin, was purified from the venom of the Vipera lebetina obtusa viper. Obtustatin is the shortest disintegrin yet described,... 
MIGRATION | DISINTEGRINS | COLLAGEN | ONCOLOGY | ANGIOSTATIN | TUMOR-GROWTH | DOMAINS | ENDOSTATIN
Journal Article
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 05/2006, Volume 4, Issue 5, pp. 1095 - 1106
Background:  Angiogenesis, the growth of new capillaries from pre‐existing blood vessels, is regulated by a balance between its promoters and inhibitors.... 
angiostatin | plasminogen activators | matrix metalloproteinases | angiogenesis | platelets | Angiogenesis | Plasminogen activators | Matrix metalloproteinases | Angiostatin | Platelets |