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anticardiolipin antibodies (302) 302
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ARTHRITIS & RHEUMATOLOGY, ISSN 2326-5191, 08/2015, Volume 67, Issue 8, pp. 2196 - 2204
Objective. It has been suggested that only antibodies against domain 1 (D1) of beta(2)-glycoprotein I (beta(2)GPI) are pathogenic and diagnostic. The role of... 
AUTOANTIBODIES | DIAGNOSIS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | SYNDROME APS | RECOGNIZE | THROMBOSIS | BETA-2-GLYCOPROTEIN-I | ASSAYS | RHEUMATOLOGY | ANTI-BETA-GLYCOPROTEIN-I ANTIBODIES | CLASSIFICATION CRITERIA
Journal Article
BLOOD, ISSN 0006-4971, 10/2011, Volume 118, Issue 15, pp. 4231 - 4238
In vitro studies have documented beta 2 glycoprotein I (beta 2GPI) binding to endothelial cells (ECs) and trophoblast using antiphospholipid antibodies. The in... 
INTERNATIONAL CONSENSUS STATEMENT | DEFINITE ANTIPHOSPHOLIPID SYNDROME | BETA-GLYCOPROTEIN I | COMPLEMENT ACTIVATION | MEDIATED THROMBOSIS | ENDOTHELIAL ACTIVATION | INDUCED FETAL LOSS | ANTI-BETA-GLYCOPROTEIN-I ANTIBODIES | HEMATOLOGY | CLASSIFICATION CRITERIA | TISSUE FACTOR
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 02/2006, Volume 4, Issue 2, pp. 295 - 306
Journal Article
HAEMATOLOGICA, ISSN 0390-6078, 08/2017, Volume 102, Issue 8, pp. 1324 - 1332
ntiphospholipid antibody syndrome is an autoimmune disease characterized by the presence of so-called antiphospholipid antibodies and clinical manifestations... 
AUTOANTIBODIES | HUMAN ANTIPHOSPHOLIPID ANTIBODIES | BETA-GLYCOPROTEIN I | AUTOIMMUNITY | TOLL-LIKE RECEPTOR | DOMAIN-I | BETA-2-GLYCOPROTEIN-I | INFECTION | ANTI-BETA-GLYCOPROTEIN-I ANTIBODIES | HEMATOLOGY | BINDING
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2014, Volume 371, Issue 4, pp. 303 - 312
This study shows that the mTORC pathway is central to the antiphospholipid syndrome. Among patients with kidney transplants and antiphospholipid syndrome, 70%... 
RAPAMYCIN | BETA-GLYCOPROTEIN-I | MEDICINE, GENERAL & INTERNAL | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ANGIOPLASTY | ANTIBODY-MEDIATED REJECTION | POLYCYSTIC KIDNEY-DISEASE | SMOOTH-MUSCLE-CELLS | ANTI-BETA-GLYCOPROTEIN-I ANTIBODIES | SYNDROME NEPHROPATHY | VASCULOPATHY | Endothelium, Vascular - cytology | Cell Proliferation | Kidney - blood supply | Kidney - pathology | TOR Serine-Threonine Kinases - metabolism | Humans | Immunoglobulin G | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Antiphospholipid Syndrome - complications | TOR Serine-Threonine Kinases - antagonists & inhibitors | Autopsy | Adult | Female | Antiphospholipid Syndrome - metabolism | Immunosuppressive Agents - pharmacology | Kidney Diseases - metabolism | Sirolimus - therapeutic use | Antiphospholipid Syndrome - drug therapy | Kidney Transplantation | Sirolimus - pharmacology | Antibodies, Antiphospholipid - metabolism | Analysis of Variance | Endothelium, Vascular - metabolism | Endothelium, Vascular - pathology | Kidney Diseases - etiology | Metabolic Networks and Pathways - drug effects | Care and treatment | Rapamycin | Health aspects | Antiphospholipid syndrome | TOR protein | Cell proliferation | Lupus | Heart attacks | Kidneys | Transplants & implants | Sirolimus | AKT protein | Antiphospholipid antibodies | Kinases | Thrombosis | Endothelial cells | Endothelium | 1-Phosphatidylinositol 3-kinase | Vascular diseases | Nephropathy | Biopsy | Autoimmune diseases | Kidney transplantation
Journal Article
JOURNAL OF RHEUMATOLOGY, ISSN 0315-162X, 01/2011, Volume 38, Issue 1, pp. 64 - 68
Objective. IgA isotypes of anticardiolipin and anti-beta(2) glycoprotein I (anti-beta(2)-GPI) are omitted from the revised antiphospholipid syndrome (APS)... 
ANTICARDIOLIPIN | SYSTEMIC LUPUS ERYTHEMATOSUS | PRIMARY SJOGRENS-SYNDROME | REVISED CRITERIA | THROMBOSIS | FREQUENCY | ANTIPHOSPHOLIPID ANTIBODIES | CLASSIFICATION | COHORT | PREVALENCE | RHEUMATOLOGY | ANTI-beta-GLYCOPROTEIN I
Journal Article
Autoimmunity Reviews, ISSN 1568-9972, 2009, Volume 9, Issue 5, pp. A299 - A304
Abstract Antiphospholipid antibodies (aPL) can be detected by functional (lupus anticoagulant) and/or by solid phase assays (anti-cardiolipin and anti-beta2... 
Allergy and Immunology | Epidemiology | Antiphospholipid antibody | Antiphospholipid syndrome | BETA-GLYCOPROTEIN-I | SYSTEMIC-LUPUS-ERYTHEMATOSUS | RISK-FACTORS | ANTICARDIOLIPIN ANTIBODIES | VENOUS THROMBOSIS | IMMUNOLOGY | AUTOIMMUNE-DISEASES | GLYCOPROTEIN-I ANTIBODIES | ANTI-BETA-GLYCOPROTEIN-I ANTIBODIES | TISSUE FACTOR | RECURRENT FETAL LOSS
Journal Article
PLOS ONE, ISSN 1932-6203, 08/2010, Volume 5, Issue 8
Background: The clinical utility of testing for antiphospholipid antibodies (aPL) of IgA isotype remains controversial. Methodology/Principal Findings: To... 
REVISED CRITERIA | THROMBOSIS | ANTICARDIOLIPIN ANTIBODIES | BIOLOGY | CLASSIFICATION | ANTIPHOSPHOLIPID SYNDROME | ANTI-BETA-GLYCOPROTEIN I | CLINICAL-SIGNIFICANCE | MANIFESTATIONS
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 08/2019, Volume 102, pp. 159 - 166
Antiphospholipid syndrome (APS) is an autoimmune thrombophilia characterized by recurrent thromboembolism and/or pregnancy morbidity in the presence of... 
CELL-ADHESION MOLECULE-1 | ACTIVATION | DNA METHYLATION | ENDOTHELIAL-CELLS | GENE-EXPRESSION | FACTOR EXPRESSION | IMMUNOLOGY | ANTI-BETA-GLYCOPROTEIN-I ANTIBODIES | TET PROTEINS | BINDING | HISTONE DEACETYLASE 9 | Hydrogen sulfide | Autoimmunity | Epigenetic inheritance | Autoantibodies | Interleukins | Analysis | Genes | Thromboembolism | Methylation | Gene expression
Journal Article
AUTOIMMUNITY REVIEWS, ISSN 1568-9972, 12/2018, Volume 17, Issue 12, pp. 1186 - 1201
Journal Article
CLINICA CHIMICA ACTA, ISSN 0009-8981, 09/2016, Volume 460, pp. 107 - 113
Background: The objective of this investigation was to examine the clinical significance of IgA anti-beta(2) glycoprotein I (anti-beta(2)GPI) antibodies and... 
ANTIBODIES | CRITERIA | ANTI-BETA-GLYCOPROTEIN-I | ANTICOAGULANT | 13TH INTERNATIONAL-CONGRESS | ANTICARDIOLIPIN | TASK-FORCE | Anti-beta glycoprotein I antibodies | Performance characteristics | UPDATE | Diagnosis | MEDICAL LABORATORY TECHNOLOGY | ASSOCIATION | Antiphospholipid syndrome
Journal Article
Blood, ISSN 0006-4971, 01/2007, Volume 109, Issue 2, pp. 422 - 430
Journal Article
AUTOIMMUNITY REVIEWS, ISSN 1568-9972, 12/2018, Volume 17, Issue 12, pp. 1210 - 1218
Journal Article
BLOOD, ISSN 0006-4971, 10/2012, Volume 120, Issue 16, pp. 3360 - 3370
beta(2)-glycoprotein I (beta(2)GPI) is the major antigenic target for antiphospholipid Abs. Anti-beta(2)GPI Abs are a heterogeneous population of Igs targeting... 
IMMUNE-RESPONSE | SYSTEMIC-LUPUS-ERYTHEMATOSUS | TUMOR-NECROSIS-FACTOR | ANTI-BETA-2-GLYCOPROTEIN-I ANTIBODIES | INTERNATIONAL CONSENSUS STATEMENT | DEFINITE ANTIPHOSPHOLIPID SYNDROME | TOLL-LIKE RECEPTOR | ANTI-BETA-GLYCOPROTEIN-I ANTIBODIES | HEMATOLOGY | CLASSIFICATION CRITERIA | TISSUE FACTOR EXPRESSION
Journal Article