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1. Full Text EGFR-targeted therapy
by Vecchione, Loredana and Jacobs, Bart and Normanno, Nicola and Ciardiello, Fortunato and Tejpar, Sabine
Experimental cell research, ISSN 0014-4827, 2011, Volume 317, Issue 19, pp. 2765 - 2771
Oncogenic dependency | Anti-EGFR inhibitors | Personalized cancer therapy | EGFR signaling | Molecular subgroups | Colorectal cancer | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasms - metabolism | Receptor, Epidermal Growth Factor - genetics | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Humans | Proto-Oncogene Proteins - genetics | Antineoplastic Agents - therapeutic use | Neoplasms - drug therapy | Mutation - physiology | Drug Resistance, Neoplasm - genetics | Receptor, Epidermal Growth Factor - metabolism | Animals | Neoplasms - genetics | Protein Kinase Inhibitors - therapeutic use | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Molecular Targeted Therapy - methods | Care and treatment | Cancer | Cellular biology | Cancer therapies | Tumors | Index Medicus
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2. Full Text Response to Anti-EGFR Therapy in Patients with BRAF non-V600-Mutant Metastatic Colorectal Cancer
by Yaeger, Rona and Kotani, Daisuke and Mondaca, Sebastian and Parikh, Aparna R and Bando, Hideaki and Van Seventer, Emily E and Taniguchi, Hiroya and Zhao, HuiYong and Thant, Claire N and de Stanchina, Elisa and Rosen, Neal and Corcoran, Ryan B and Yoshino, Takayuki and Yao, Zhan and Ebi, Hiromichi
Clinical cancer research, ISSN 1078-0432, 12/2019, Volume 25, Issue 23, pp. 7089 - 7097
Life Sciences & Biomedicine | Oncology | Science & Technology | Index Medicus | BRAF non-V600 mutation | anti-EGFR therapy | colorectal cancer
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3. Full Text Targeting the EGFR signaling pathway in cancer therapy
by Seshacharyulu, Parthasarathy and Ponnusamy, Moorthy P and Haridas, Dhanya and Jain, Maneesh and Ganti, Apar K and Batra, Surinder K
Expert opinion on therapeutic targets, ISSN 1472-8222, 01/2012, Volume 16, Issue 1, pp. 15 - 31
EGFR mutations | signaling | anti-EGFR therapy | cancer | EGFR inhibitors | therapeutic targets | EGFR | Signaling | Anti-EGFR therapy | Cancer | Therapeutic targets | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Neoplasms - metabolism | Receptor, Epidermal Growth Factor - metabolism | Animals | Signal Transduction - drug effects | Humans | Antibodies, Monoclonal - therapeutic use | Antineoplastic Agents - therapeutic use | Neoplasms - drug therapy | Protein-Tyrosine Kinases - antagonists & inhibitors | Index Medicus
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4. Full Text Blood‐based detection of RAS mutations to guide anti‐EGFR therapy in colorectal cancer patients: concordance of results from circulating tumor DNA and tissue‐based RAS testing
by Schmiegel, Wolff and Scott, Rodney J and Dooley, Susan and Lewis, Wendy and Meldrum, Cliff J and Pockney, Peter and Draganic, Brian and Smith, Steve and Hewitt, Chelsee and Philimore, Hazel and Lucas, Amanda and Shi, Elva and Namdarian, Kateh and Chan, Timmy and Acosta, Danilo and Ping‐Chang, Su and Tannapfel, Andrea and Reinacher‐Schick, Anke and Uhl, Waldemar and Teschendorf, Christian and Wolters, Heiner and Stern, Josef and Viebahn, Richard and Friess, Helmut and Janssen, Klaus‐Peter and Nitsche, Ulrich and Slotta‐Huspenina, Julia and Pohl, Michael and Vangala, Deepak and Baraniskin, Alexander and Dockhorn‐Dworniczak, Barbara and Hegewisch‐Becker, Susanne and Ronga, Philippe and Edelstein, Daniel L and Jones, Frederick S and Hahn, Stephan and Fox, Stephen B
Molecular oncology, ISSN 1574-7891, 02/2017, Volume 11, Issue 2, pp. 208 - 219
plasma | CRC | anti‐EGFR therapy | ctDNA | RAS mutations | anti-EGFR therapy | Life Sciences & Biomedicine | Oncology | Science & Technology | ErbB Receptors - antagonists & inhibitors | DNA, Neoplasm - blood | Colorectal Neoplasms - blood | Colorectal Neoplasms - drug therapy | Colorectal Neoplasms - genetics | Humans | Female | Male | Aged | DNA, Neoplasm - genetics | Mutation | Genes, ras | Plasma | Epidermal growth factor receptors | Colorectal carcinoma | Colorectal cancer | Metastasis | Paraffin | Patients | Blood | Metastases | Ethics | Histopathology | Epidermal growth factor | Agreements | Clinical medicine | Deoxyribonucleic acid--DNA | DNA sequencing | Tumors | Index Medicus
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5. Full Text HER2-targeted therapy should be shifted towards an earlier line for patients with anti-EGFR-therapy naïve, HER2-amplified metastatic colorectal cancer
by Nakamura, Yoshiaki and Sawada, Kentaro and Fujii, Satoshi and Yoshino, Takayuki
ESMO open, ISSN 2059-7029, 07/2019, Volume 4, Issue 3, pp. e000530 - e000530
Life Sciences & Biomedicine | Oncology | Science & Technology
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6. Full Text Acquired resistance to EGFR-targeted therapies in colorectal cancer
by Van Emburgh, Beth O and Sartore-Bianchi, Andrea and Di Nicolantonio, Federica and Siena, Salvatore and Bardelli, Alberto
Molecular oncology, ISSN 1574-7891, 09/2014, Volume 8, Issue 6, pp. 1084 - 1094
Acquired resistance | RAS | Panitumumab | Colorectal cancer | Cetuximab | Anti-EGFR therapy | MET | Life Sciences & Biomedicine | Oncology | Science & Technology | ErbB Receptors - antagonists & inhibitors | ErbB Receptors - metabolism | Colon - pathology | Rectum - pathology | Humans | Rectum - metabolism | Colon - drug effects | ras Proteins - metabolism | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Colon - metabolism | Animals | MAP Kinase Signaling System - drug effects | Rectum - drug effects | Signal Transduction - drug effects | Colorectal Neoplasms - drug therapy | Antineoplastic Agents - pharmacology | Colorectal Neoplasms - pathology | Proto-Oncogene Proteins c-akt - metabolism | Colorectal Neoplasms - metabolism | Tyrosine | Health aspects | Phosphotransferases | Analysis | Genes | Immunoglobulins | Epidermal growth factor receptors | Tumor cells | Colorectal carcinoma | Extracellular signal-regulated kinase | Raf protein | AKT protein | Metastasis | Kinases | Cancer therapies | Metastases | Signal transduction | Epidermal growth factor | Xenografts | Monoclonal antibodies | Biomarkers | Mutation | Vascular endothelial growth factor | Index Medicus | Reviews | Review
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7. Full Text Anti‐Epidermal Growth Factor Receptor Therapy in Head and Neck Squamous Cell Carcinoma: Focus on Potential Molecular Mechanisms of Drug Resistance
by Boeckx, Carolien and Baay, Marc and Wouters, An and Specenier, Pol and Vermorken, Jan B and Peeters, Marc and Lardon, Filip
The oncologist (Dayton, Ohio), ISSN 1083-7159, 07/2013, Volume 18, Issue 7, pp. 850 - 864
Head and neck squamous cell carcinoma | Anti‐EGFR therapy | Intrinsic and acquired resistance | Cetuximab | Anti-EGFR therapy | Life Sciences & Biomedicine | Oncology | Science & Technology | Receptor, Epidermal Growth Factor - genetics | Antibodies, Monoclonal, Humanized - therapeutic use | Signal Transduction | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Carcinogenesis - genetics | Head and Neck Neoplasms - drug therapy | Neoplasm Recurrence, Local - drug therapy | Molecular Targeted Therapy | Head and Neck Neoplasms - pathology | Neoplasm Recurrence, Local - pathology | Protein Kinase Inhibitors - administration & dosage | Drug Resistance, Neoplasm - genetics | Carcinoma, Squamous Cell - drug therapy | Receptor, Epidermal Growth Factor - therapeutic use | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Head and Neck Neoplasms - genetics | Neoplasm Recurrence, Local - genetics | Index Medicus | Head and Neck Cancers
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