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1. Full Text Efficacy and safety of omalizumab in patients with chronic idiopathic/spontaneous urticaria who remain symptomatic on h 1 antihistamines: A randomized, placebo-controlled study
by Saini, Sarbjit S and Bindslev-Jensen, Carsten and Maurer, Marcus and Grob, Jean-Jacques and Bülbül Baskan, Emel and Bradley, Mary S and Canvin, Janice and Rahmaoui, Abdelkader and Georgiou, Panayiotis and Alpan, Oral and Spector, Sheldon and Rosén, Karin
Journal of Investigative Dermatology, ISSN 0022-202X, 01/2015, Volume 135, Issue 1, pp. 67 - 75
ASTERIA I was a 40-week, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of subcutaneous omalizumab as add-on therapy... 
DIAGNOSIS | THERAPY | ANTI-IGE OMALIZUMAB | CHRONIC IDIOPATHIC URTICARIA | DERMATOLOGY
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2. Full Text Efficacy of omalizumab in patients with atopic dermatitis: A systematic review andmeta-analysis
by Wang, HH and Md, YCL and Huang, YC
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, ISSN 0091-6749, 12/2016, Volume 138, Issue 6, pp. 1719 - 1719
ALLERGY | ECZEMA | IMMUNOLOGY | ANTI-IGE THERAPY
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3. IgG Anti-IgE Autoantibodies in Visceral Leishmaniasis
by Atta, A. M and Sousa-Atta, M. L. B and D'Oliveira, A and Almeida, R. P and Araújo, M. I and Carvalho, E. M
IgG Anti-IgE Autoantibodies in Visceral Leishmaniasis, 12/2002
Procedures for IgG depletion in visceral leishmaniasis (VL) and schistosomiasis sera using Sepharose-protein G beads also deplete IgE. In this study, the... 
IgE, IgG anti-IgE, protein G, visceral leishmaniasis, schistosomiasis mansoni
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4. Anti-IgE for treatment of Polyposis nasi
by Arnold, A and Biedermann, T and Darsow, U
Allergologie, ISSN 0344-5062, 12/2018, Volume 41, Issue 12, pp. 568 - 570
Polyposis nasi | Anti-IgE Treatment
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5. Full Text Experiência clínica com omalizumab na consulta de asma grave
by Alfarrobaa, S and Videiraa, W and Galvão-Lucasa, C and Carvalhob, F and Bárbaraa, C
Revista Portuguesa de Pneumologia, ISSN 0873-2159, 2014, Volume 20, Issue 2, pp. 78 - 83
Background: It is widely recognized that asthma control is not always possible in patients with very severe asthma despite available treatment. The aim of this... 
Omalizumab | Anti IgE | Asthma
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6. Full Text Type 2 inflammation in asthma--present in most, absent in many
by Fahy, John V and Fahy, John V
Nature Reviews Immunology, ISSN 1474-1733, 01/2015, Volume 15, Issue 1, pp. 57 - 65
Asthma is one of the most common chronic immunological diseases in humans, affecting people from childhood to old age. Progress in treating asthma has been... 
TO-MODERATE ASTHMA | SEVERE EOSINOPHILIC ASTHMA | SPUTUM EOSINOPHILIA | ALLERGIC-ASTHMA | AIRWAY INFLAMMATION | HUMANIZED MONOCLONAL-ANTIBODY | PERSISTENT ASTHMA | IMMUNOLOGY | ANTI-IGE ANTIBODY | DEPENDENT ASTHMA | BRONCHIAL-ASTHMA | Asthma - metabolism | Cytokines - metabolism | Immunomodulation | Humans | Inflammation - immunology | Th2 Cells - immunology | Asthma - drug therapy | Th2 Cells - metabolism | Inflammation - metabolism | Phenotype | Animals | Inflammation - drug therapy | Asthma - immunology | Inflammation Mediators - metabolism | Asthma - pathology | Care and treatment | Physiological aspects | Inflammation | Genetic aspects | Research | B cells | Risk factors | Asthma
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7. Drugs targeting type 2 inflammation/lipid mediators-Anti-IgE antibody and CRTH 2 antagonists
by Asano, Koichiro
Japanese Journal of Allergology, ISSN 0021-4884, 2019, Volume 68, Issue 1, pp. 8 - 14
Prostaglndin D2 | CRTh2 antagonists | Anti-IgE antibody
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8. Full Text Omalizumab-Therapie atopischer Dermatitis: IgE-Depletion führt nicht zur klinischen Besserung - Eine randomisierte, placebo-kontrollierte, doppelblinde Pilotstudie
by Heil, Peter Maximilian and Maurer, Dieter and Klein, Brigitte and Hultsch, Thomas and Stingl, Georg
JDDG - Journal of the German Society of Dermatology, ISSN 1610-0379, 12/2010, Volume 8, Issue 12, pp. 990 - 999
IgE receptor | anti-IgE | IgE depletion | Omalizumab | atopic dermatitis | surface-bound IgE
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9. Full Text Consensus-based European guidelines for treatment of atopic eczema (atopic dermatitis) in adults and children: partII
by Wollenberg, A and Barbarot, S and Bieber, T and Christen-Zaech, S and Deleuran, M and Fink-Wagner, A and Gieler, U and Girolomoni, G and Lau, S and Muraro, A and Czarnecka-Operacz, M and Schafer, T and Schmid-Grendelmeier, P and Simon, D and Szalai, Z and Szepietowski, JC and Taieb, A and Torrelo, A and Werfel, T and Ring, J and EAACI and European Union Med Specialists and Global Allergy Asthma European and EDF and European Federation Allergy and ESPD and ESDaP and EADV and ETFAD
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, ISSN 0926-9959, 06/2018, Volume 32, Issue 6, pp. 850 - 878
This guideline was developed as a joint interdisciplinary European project, including physicians from all relevant disciplines as well as patients. It is a... 
VITAMIN-D SUPPLEMENTATION | EVENING PRIMROSE OIL | CHINESE HERBAL MEDICINE | RANDOMIZED CONTROLLED-TRIAL | PLACEBO-CONTROLLED TRIAL | ALLERGEN-SPECIFIC IMMUNOTHERAPY | STAPHYLOCOCCUS-AUREUS COLONIZATION | LONG-TERM TREATMENT | ANTI-IGE THERAPY | CLASSICAL HOMEOPATHIC TREATMENT | DERMATOLOGY
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10. Full Text Omalizumab treatment downregulates dendritic cell FcεRI expression
by Prussin, Calman and Griffith, Daniel T and Boesel, Kevin M and Lin, Henry and Foster, Barbara and Casale, Thomas B
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 2003, Volume 112, Issue 6, pp. 1147 - 1154
Background: Dendritic cells (DCs) are potent antigen-presenting cells that express FcεRI, the high-affinity IgE receptor. Although the downregulation of... 
anti-IgE | FcεRI | omalizumab | antigen-presenting cells | Dendritic cells | IgE | Omalizumab | Anti-IgE | Antigen-presenting cells
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11. Full Text Omalizumab for the Treatment of Chronic Idiopathic or Spontaneous Urticaria
by Maurer, Marcus and Rosén, Karin and Hsieh, Hsin-Ju and Saini, Sarbjit and Grattan, Clive and Gimenéz-Arnau, Ana and Agarwal, Sunil and Doyle, Ramona and Canvin, Janice and Kaplan, Allen and Casale, Thomas
The New England Journal of Medicine, ISSN 0028-4793, 03/2013, Volume 368, Issue 10, pp. 924 - 935
This large, randomized, placebo-controlled trial showed the efficacy of omalizumab, an injectable anti–IgE humanized monoclonal antibody, in the treatment of... 
MEDICINE, GENERAL & INTERNAL | IMPACT | ANTI-IGE OMALIZUMAB | DAILY DIARY | EPSILON-RI EXPRESSION | LIFE | Antibodies, Anti-Idiotypic - adverse effects | Severity of Illness Index | Antibodies, Monoclonal, Humanized - adverse effects | Antibodies, Monoclonal, Humanized - therapeutic use | Double-Blind Method | Humans | Middle Aged | Omalizumab | Male | Urticaria - complications | Anti-Allergic Agents - therapeutic use | Young Adult | Urticaria - drug therapy | Pruritus - drug therapy | Adolescent | Anti-Allergic Agents - adverse effects | Intention to Treat Analysis | Adult | Female | Pruritus - etiology | Aged | Antibodies, Anti-Idiotypic - therapeutic use | Child | Chronic Disease | Treatment outcome | Dosage and administration | Diagnosis | Drug therapy | Urticaria | Antihistamines | Clinical trials | Licenses | Immunoglobulin E | Cardiovascular disease | Patients | Dermatitis | Regulatory approval | Quality of life | Monoclonal antibodies | Drug dosages
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12. Full Text Omalizumab-induced reductions in mast cell FcεRI expression and function
by Beck, Lisa A and Marcotte, Gregory V and MacGlashan, Donald and Togias, Alkis and Saini, Sarbjit
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 2004, Volume 114, Issue 3, pp. 527 - 530
By design, omalizumab binds free IgE in the circulation and prevents its attachment to the surface of mast cells and basophils, thereby preventing them from... 
Mast cells | FcεRI | omalizumab | basophils | ALLERGY | Fc epsilon RI | IN-VIVO | DOWN-REGULATION | IMMUNOLOGY | mast cells | ANTI-IGE ANTIBODY
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13. Full Text Exploring the effects of omalizumab in allergic asthma: An analysis of biomarkers in the EXTRA study
by Hanania, Nicola A and Wenzel, Sally and Roseń, Karin and Hsieh, Hsin-Ju and Mosesova, Sofia and Choy, David F and Lal, Preeti and Arron, Joseph R and Harris, Jeffrey M and Busse, William
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 04/2013, Volume 187, Issue 8, pp. 804 - 811
Rationale: For many patients with asthma, allergic airway inflammation is primarily a Th2-weighted process; however, heterogeneity in patterns of inflammation... 
Immunoglobulin E | Fractional exhaled nitric oxide | Severe asthma | Eosinophil | Periostin | periostin | SAFETY | MONOCLONAL-ANTIBODY | IL-13 | immunoglobulin E | THERAPY | fractional exhaled nitric oxide | RESPIRATORY SYSTEM | INFLAMMATION | severe asthma | EXACERBATIONS | eosinophil | ANTI-IGE ANTIBODY | CRITICAL CARE MEDICINE | Anti-Asthmatic Agents - adverse effects | Antibodies, Anti-Idiotypic - adverse effects | Anti-Asthmatic Agents - therapeutic use | Humans | Middle Aged | Omalizumab | Male | Nitric Oxide - analysis | Young Adult | Antibodies, Anti-Idiotypic - administration & dosage | Antibodies, Monoclonal, Humanized - administration & dosage | Adult | Female | Antibodies, Anti-Idiotypic - therapeutic use | Child | Cell Adhesion Molecules - blood | Antibodies, Monoclonal, Humanized - adverse effects | Antibodies, Monoclonal, Humanized - therapeutic use | Biomarkers - analysis | Breath Tests | Asthma - drug therapy | Asthma - genetics | Disease Progression | Adolescent | Aged | Anti-Asthmatic Agents - administration & dosage | Eosinophils
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14. Full Text Omalizumab rescue therapy for refractory status asthmaticus
by Milger, Katrin and Schroeder, Ines and Behr, Jürgen and Meis, Tobias and Wulffen, Werner V and Kneidinger, Nikolaus
Annals of Internal Medicine, ISSN 0003-4819, 2019, Volume 170, Issue 5, pp. 351 - 352
MEDICINE, GENERAL & INTERNAL | ANTI-IGE
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15. Anti-IgE and biologic approaches for the treatment of asthma
by Mitchell, Patrick D and El-Gammal, Amani I and O’Byrne, Paul M
Handbook of Experimental Pharmacology, ISSN 0171-2004, 2016, Volume 237, pp. 131 - 152
Monoclonal antibodies | Severe refractory asthma | Anti-IgE | Biologics
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16. Full Text Anti-IgE treatment in allergic rhinitis
by Bayar Muluk, Nuray and Bafaqeeh, Sameer Ali and Cingi, Cemal
International Journal of Pediatric Otorhinolaryngology, ISSN 0165-5876, 12/2019, Volume 127, p. 109674
To review the efficacy of anti-IgE therapy in allergic rhinitis (AR). Literature search was performed using the PubMed and Proquest Central databases at... 
Omalizumab | Anti-IgE treatment | Seasonal allergic rhinitis | Perennial allergic rhinitis | Allergic rhinitis
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17. Full Text Omalizumab is effective in allergic and nonallergic patients with nasal polyps and asthma
by Gevaert, Philippe, MD, PhD and Calus, Lien, MD and Van Zele, Thibaut, MD, PhD and Blomme, Katrien, MSc and De Ruyck, Natalie, MSc and Bauters, Wouter, MD, PhD and Hellings, Peter, MD, PhD and Brusselle, Guy, MD, PhD and De Bacquer, Dirk, MD, PhD and van Cauwenberge, Paul, MD, PhD and Bachert, Claus, MD, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 131, Issue 1, pp. 110 - 116.e1
Background Adult patients with nasal polyps often have comorbid asthma, adding to the serious effect on the quality of life of these patients. Nasal polyps and... 
Allergy and Immunology | Omalizumab | anti-IgE | asthma | local IgE | quality of life | nasal polyposis | ANTIBODIES | PROTEIN | RHINOSINUSITIS | STAPHYLOCOCCUS-AUREUS ENTEROTOXINS | IMMUNOLOGY | CHRONIC SINUSITIS | CHILDREN | THERAPY | ALLERGY | INFLAMMATION | EXPRESSION | Antibodies, Anti-Idiotypic - adverse effects | Antibodies, Monoclonal, Humanized - adverse effects | Nasal Polyps - immunology | Antibodies, Monoclonal, Humanized - therapeutic use | Humans | Middle Aged | Male | Treatment Outcome | Nasal Polyps - drug therapy | Asthma - drug therapy | Anti-Allergic Agents - therapeutic use | Nasal Polyps - complications | Asthma - complications | Anti-Allergic Agents - adverse effects | Asthma - immunology | Adult | Female | Antibodies, Anti-Idiotypic - therapeutic use | Comorbidity | Immunoglobulin E | Respiratory agents | Universities and colleges | Nasal polyps | Health aspects | Asthma | Hospitals | Mental health | Ear diseases | Otolaryngology | Drug therapy | Allergies
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18. Screening of Shuanghuanglian Injection allergenic ingredients based on immune fingerprint
by Wen, Wen and He, Fu-Yuan and Liu, Wen-Long and Zhou, Yi-Qun and Liu, Hong-Yu
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, ISSN 1001-5302, 04/2019, Volume 44, Issue 8, pp. 1588 - 1595
supramolecular | anaphylactoid | Shuanghuanglian Injection | anti-IgE antibody | immune fingerprint
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19. Full Text Omalizumab for asthma in adults and children
by Normansell, Rebecca and Normansell, Rebecca and Walker, Samantha and Walker, Samantha and Milan, Stephen J and Milan, Stephen J and Walters, E Haydn and Walters, E. Haydn and Nair, Parameswaran and Nair, Parameswaran
The Cochrane database of systematic reviews, ISSN 1469-493X, 2014, Volume 1, Issue 1, p. CD003559
Background Asthma is a respiratory (airway) condition that affects an estimated 300 million people worldwide and is associated with significant morbidity and... 
Adrenal Cortex Hormones [therapeutic use] | Humans | SEVERE ALLERGIC-ASTHMA | PULMONARY-FUNCTION | SPUTUM HYALURONAN | ANTIIMMUNOGLOBULIN-E ANTIBODY | Randomized Controlled Trials as Topic | Antibodies, Monoclonal, Humanized | ADD-ON THERAPY | MEDICINE, GENERAL & INTERNAL | Antibodies, Anti-Idiotypic [therapeutic use] | Antibodies, Monoclonal [therapeutic use] | SEVERE PERSISTENT ASTHMA | DOUBLE-BLIND | Adult | HUMANIZED MONOCLONAL-ANTIBODY | QUALITY-OF-LIFE | Immunoglobulin E [blood; immunology] | ANTI-IGE ANTIBODY | Asthma [drug therapy immunology] | Chronic Disease | Child | Anti-Asthmatic Agents [therapeutic use] | Antibodies, Monoclonal, Humanized - therapeutic use | Anti-Asthmatic Agents - therapeutic use | Omalizumab | Adrenal Cortex Hormones - therapeutic use | Asthma - drug therapy | Immunoglobulin E - blood | Antibodies, Anti-Idiotypic - administration & dosage | Antibodies, Monoclonal, Humanized - administration & dosage | Immunoglobulin E - immunology | Injections, Subcutaneous | Asthma - immunology | Anti-Asthmatic Agents - administration & dosage | Antibodies, Anti-Idiotypic - therapeutic use
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