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Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2008, Volume 358, Issue 12, pp. 1215 - 1228
Journal Article
Current Opinion in Allergy and Clinical Immunology, ISSN 1528-4050, 08/2015, Volume 15, Issue 4, pp. 392 - 396
Journal Article
Journal Article
Journal Article
Expert Opinion on Biological Therapy, ISSN 1471-2598, 02/2013, Volume 13, Issue 2, pp. 295 - 302
Journal Article
Journal Article
Journal Article
Clinical Pharmacokinetics, ISSN 0312-5963, 4/2011, Volume 50, Issue 4, pp. 215 - 227
Mepolizumab is a fully humanized monoclonal antibody (IgG1/κ) targeting human interleukin-5 (IL-5), a key haematopoietin needed for eosinophil development and... 
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Research-and-development | Atopic-dermatitis | Renal-impairment | Interleukin-5-receptor-antagonists, pharmacodynamics | eosinophilic oesophagitis | Asthma | Monoclonal- antibodies, pharmacodynamics | Hypereosinophilic- syndrome | Interleukin-5-receptor-antagonists, pharmacokinetics | Mepolizumab, pharmacokinetics | Monoclonal-antibodies, pharmacokinetics | Liver-dysfunction | Mepolizumab, pharmacodynamics | HUMAN INTERLEUKIN-5 | ATOPIC-DERMATITIS | THERAPY | MESSENGER-RNA EXPRESSION | DISEASE | ANTI-IL-5 MAB | PERSISTENT ASTHMA | PHARMACOLOGY & PHARMACY | HISTAMINE-RELEASE | HYPEREOSINOPHILIC-SYNDROMES | EOSINOPHILIC ESOPHAGITIS | Eosinophilia - metabolism | Asthma - metabolism | Eosinophils - drug effects | Antibodies, Monoclonal - pharmacology | Humans | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - pharmacokinetics | Antibodies, Monoclonal - therapeutic use | Renal Insufficiency - metabolism | Asthma - drug therapy | Eosinophils - immunology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Antibodies, Monoclonal, Humanized | Animals | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Dermatitis, Atopic - drug therapy | Interleukin-5 - antagonists & inhibitors | Eosinophilia - immunology | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Asthma - immunology | Dermatitis, Atopic - immunology | Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics | Eosinophilia - drug therapy | Dermatitis, Atopic - metabolism | Monoclonal antibodies | Complications and side effects | Dosage and administration | Research | Pharmacokinetics
Journal Article