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1. Controversies in science and technology
: from maize to menopause
by Kinchy, Abby J and Kleinman, Daniel Lee and Handelsman, Jo
2005, ISBN 9780299203948, xii, 341
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2. Full Text Two-Year Combination Antibiotic Therapy With Clarithromycin, Rifabutin, and Clofazimine for Crohn's Disease
by Selby, Warwick and Pavli, Paul and Crotty, Brendan and Florin, Tim and Radford-Smith, Graham and Gibson, Peter and Mitchell, Brent and Connell, William and Read, Robert and Merrett, Michael and Ee, Hooi and Hetzel, David and Crohn's Disease Study Grp and Antibiotics in Crohn's Disease Study Group
Gastroenterology, ISSN 0016-5085, 2007, Volume 132, Issue 7, pp. 2313 - 2319
Background & Aims: Mycobacterium avium subspecies paratuberculosis has been proposed as a cause of Crohn's disease. We report a prospective, parallel,... 
AVIUM SUBSP PARATUBERCULOSIS | RANDOMIZED CONTROLLED TRIAL | ETHAMBUTOL | ANTIMYCOBACTERIAL THERAPY | MYCOBACTERIA | PLACEBO | CLINICAL-TRIAL | DOUBLE-BLIND | RECURRENCE | GASTROENTEROLOGY & HEPATOLOGY | CIPROFLOXACIN | Glucocorticoids - administration & dosage | Glucocorticoids - therapeutic use | Prednisolone - administration & dosage | Humans | Middle Aged | Male | Rifabutin - administration & dosage | Anti-Bacterial Agents - therapeutic use | Treatment Failure | Clarithromycin - administration & dosage | Adult | Crohn Disease - microbiology | Female | Anti-Bacterial Agents - adverse effects | Prednisolone - therapeutic use | Drug Therapy, Combination | Clofazimine - therapeutic use | Double-Blind Method | Drug Administration Schedule | Rifabutin - adverse effects | Clarithromycin - adverse effects | Clofazimine - administration & dosage | Clarithromycin - therapeutic use | Mycobacterium Infections - complications | Clofazimine - adverse effects | Mycobacterium avium - classification | Crohn Disease - drug therapy | Rifabutin - therapeutic use | Patient Compliance | Anti-Bacterial Agents - administration & dosage | Clarithromycin | Crohn's disease | Clofazimine | Drug therapy, Combination | Index Medicus | Abridged Index Medicus
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3. Full Text Endoscopic and clinical responses to anti‐tubercular therapy can differentiate intestinal tuberculosis from Crohn's disease
by Pratap Mouli, V and Munot, K and Ananthakrishnan, A and Kedia, S and Addagalla, S and Garg, S. K and Benjamin, J and Singla, V and Dhingra, R and Tiwari, V and Bopanna, S and Hutfless, S and Makharia, G and Ahuja, V
Alimentary Pharmacology & Therapeutics, ISSN 0269-2813, 01/2017, Volume 45, Issue 1, pp. 27 - 36
Background Differentiation between intestinal tuberculosis and Crohn's disease is difficult and may require therapeutic trial with anti-tubercular therapy in... 
DIAGNOSIS | ANTIMYCOBACTERIAL THERAPY | INFLAMMATORY-BOWEL-DISEASE | ASIA | BIOPSY | CLOFAZIMINE | PHARMACOLOGY & PHARMACY | GASTROENTEROLOGY & HEPATOLOGY | PARATUBERCULOSIS | SACCHAROMYCES-CEREVISIAE ANTIBODY | INDIA | EPIDEMIOLOGY | Prospective Studies | Humans | Middle Aged | Tuberculosis, Gastrointestinal - drug therapy | Male | Treatment Outcome | Tuberculosis, Gastrointestinal - diagnosis | Colonoscopy - methods | Young Adult | Crohn Disease - drug therapy | Adolescent | Crohn Disease - diagnosis | Adult | Female | Retrospective Studies | Antitubercular Agents - therapeutic use | Cohort Studies | Tuberculosis | Therapy | Mucosa | Insurance agents & brokers | Crohn's disease | Confusion | Patients | Crohns disease | Endoscopes | Intestine | Healing | Diagnostic systems | Diagnosis | Colon | Endoscopy | Differentiation | Index Medicus
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4. Full Text Therapy for Mycobacterium kansasii infection: Beyond 2018
by DeStefano, Michelle S and Shoen, Carolyn M and Cynamon, Michael H
Frontiers in Microbiology, ISSN 1664-302X, 09/2018, Volume 9, pp. 2271 - 2271
The current standard of care therapy for pulmonary Mycobacterium kansasii infection is isoniazid (300 mg/day), rifampin (600 mg/day), and ethambutol (15... 
Non-tuberculous mycobacteria | Antimycobacterials | Mouse models | Pulmonary infection | M. kansasii | mouse models | CLARITHROMYCIN | NONTUBERCULOUS MYCOBACTERIA | TUBERCULOSIS | SUSCEPTIBILITY | MICROBIOLOGY | antimycobacterials | pulmonary infection | MOUSE MODEL | DRUGS | non-tuberculous mycobacteria | LUNG-DISEASE | MOXIFLOXACIN | PULMONARY-DISEASE | IN-VITRO ACTIVITY | Drug resistance in microorganisms | Mycobacterial infections | Dosage and administration | Research | Drug therapy | Rifampin | Isoniazid
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5. Full Text Spray Dried Aerosol Particles of Salts for Tuberculosis Therapy
by Durham, P.G and Zhang, Y and German, N and Mortensen, N and Dhillon, J and Mitchison, D.A and Fourie, P.B and Hickey, A.J
Molecular Pharmaceutics, ISSN 1543-8384, 08/2015, Volume 12, Issue 8, pp. 2574 - 2581
Tuberculosis is the most serious infectious disease caused by a single organism, Mycobacterium tuberculosis (Mtb). The standard of care is a protracted and... 
pyrazinoic acid salts | antimycobacterial activity | spray drying | therapeutic aerosols | pulmonary drug delivery | tuberculosis | MYCOBACTERIUM-TUBERCULOSIS | DRUG | MEDICINE, RESEARCH & EXPERIMENTAL | TUBERCLE BACILLI | DRY POWDER | CHEMOTHERAPY | DELIVERY | PYRAZINOIC ACID | CAPREOMYCIN | PYRAZINAMIDE | PHARMACOLOGY & PHARMACY
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6. Full Text Iron-Based Metal-Organic Frameworks as a Theranostic Carrier for Local Tuberculosis Therapy
by Wyszogrodzka, Gabriela and Dorożyński, Przemysław and Gil, Barbara and Roth, Wieslaw J and Strzempek, Maciej and Marszałek, Bartosz and Węglarz, Władysław P and Menaszek, Elżbieta and Strzempek, Weronika and Kulinowski, Piotr
Pharmaceutical Research, ISSN 0724-8741, 7/2018, Volume 35, Issue 7, pp. 1 - 11
The purpose of the study was initial evaluation of applicability of metal organic framework (MOF) Fe-MIL-101-NH2 as a theranostic carrier of antituberculous... 
Biochemistry, general | Biomedical Engineering | inhaled dosage forms | Biomedicine | tuberculosis treatment | Pharmacy | Medical Law | iron metal-organic framework (MOF) | MRI contrast agent | theranostic system | Pharmacology/Toxicology | ANTITUBERCULOSIS DRUGS | LUNG | AEROSOL DEPOSITION | DRUG-DELIVERY | CONTRAST AGENTS | MRI | NANOMEDICINE | RELEASE | CHEMISTRY, MULTIDISCIPLINARY | NANOPARTICLES | PHARMACOLOGY & PHARMACY | EFFICIENT | Cell Line | Iron - administration & dosage | Drug Carriers - metabolism | Antitubercular Agents - chemistry | Magnetic Resonance Spectroscopy - methods | Iron - chemistry | Drug Carriers - administration & dosage | Iron - metabolism | Drug Carriers - chemistry | Dose-Response Relationship, Drug | Animals | Theranostic Nanomedicine - methods | Fibroblasts - drug effects | Tuberculosis - drug therapy | Antitubercular Agents - administration & dosage | Antitubercular Agents - metabolism | Tuberculosis - metabolism | Fibroblasts - metabolism | Drugs | Drug delivery systems | Tuberculosis | Antitubercular agents | Respiratory agents | Contrast media | Vehicles | Scanning electron microscopy | Particle size | Nuclear magnetic resonance--NMR | Toxicity | X ray powder diffraction | Lung | Metals | Cytotoxicity | Iron | Drug delivery | Dissolution | Powder | Contrast agents | Spectrometry | Diffraction | Magnetic resonance imaging | Fibroblasts | Resonance | Safety | Antimycobacterial agents | Metal-organic frameworks | Isoniazid | Index Medicus | Research Paper
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7. Full Text Efficacy of pyrazinoic acid dry powder aerosols in resolving necrotic and non necrotic granulomas in a guinea pig model of tuberculosis
by Montgomery, SA and Young, EF and Durham, PG and Zulauf, KE and Rank, L and Miller, BK and Hayden, JD and Lin, FC and Welch, JT and Hickey, AJ and Braunstein, M
PLOS ONE, ISSN 1932-6203, 09/2018, Volume 13, Issue 9, pp. e0204495 - e0204495
New therapeutic strategies are needed to treat drug resistant tuberculosis (TB) and to improve treatment for drug sensitive TB. Pyrazinamide (PZA) is a... 
EXPERIMENTAL AIRBORNE TUBERCULOSIS | ANTIMYCOBACTERIAL ACTIVITY | PYRAZINAMIDE RESISTANCE | MURINE MODEL | IN-VITRO | STERILIZING ACTIVITY | ANTITUBERCULOSIS AGENTS | MULTIDISCIPLINARY SCIENCES | DRUG DISCOVERY | ESTERS | RESISTANT MYCOBACTERIUM-TUBERCULOSIS | Granuloma, Respiratory Tract - pathology | Tuberculosis, Pulmonary - microbiology | Granuloma, Respiratory Tract - drug therapy | Male | Tuberculosis, Pulmonary - drug therapy | Mycobacterium tuberculosis - drug effects | Necrosis | Granuloma, Respiratory Tract - microbiology | Rifampin - administration & dosage | Drug Therapy, Combination | Tuberculosis, Multidrug-Resistant - pathology | Disease Models, Animal | Pyrazinamide - administration & dosage | Dry Powder Inhalers | Guinea Pigs | Pyrazinamide - analogs & derivatives | Pyrazinamide - pharmacokinetics | Bacterial Load | Respiratory Tract Absorption | Tuberculosis, Pulmonary - pathology | Animals | Antitubercular Agents - pharmacokinetics | Aerosols | Antitubercular Agents - administration & dosage | Tuberculosis, Multidrug-Resistant - drug therapy | Drugs | Usage | Drug delivery systems | Tuberculosis | Development and progression | Dosage and administration | Drug therapy | Pyrazinamide | Health aspects | Testing | Vehicles | Spleen | Therapy | Bacilli | Liver | Infections | Drug resistance | Powder | Critical components | Medicine | Chemotherapy | Immunology | Acids | Lungs | Guinea pigs | Sterilization | Drug dosages | Rifampin | Index Medicus
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8. Full Text Effect of Antiretroviral Therapy on Treatment Outcomes in a Prospective Study of Extensively Drug-Resistant Tuberculosis (XDR-TB) HIV Coinfection Treatment in KwaZulu-Natal, South Africa
by Yuengling, Katharine A and Padayatchi, Nesri and Wolf, Allison and Mathema, Barun and Brown, Tyler and Horsburgh, C Robert and OʼDonnell, Max R
JAIDS Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 12/2018, Volume 79, Issue 4, pp. 474 - 480
BACKGROUND:Extensively drug-resistant tuberculosis (XDR-TB)/HIV coinfection has been associated with high mortality and poor TB outcomes. We performed a... 
HIV/AIDS | epidemiology | INFECTIOUS DISEASES | MULTIDRUG-RESISTANT | TRANSMISSION | treatment outcomes | tuberculosis | drug-resistance | South Africa | IMMUNOLOGY | EPIDEMIC | Antiretroviral drugs | Medical research | Therapy | Medical treatment | Mortality | Clinical trials | Genomes | Single-nucleotide polymorphism | Drug resistance | Patients | Antiretroviral therapy | Gene sequencing | Tuberculosis | Antiretroviral agents | Human immunodeficiency virus--HIV | Sputum | Antimycobacterial agents | Polymorphism
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9. Crohn's disease therapy with Dietzia: The end of anti-inflammatory drugs
by Click, Robert E
Future Microbiology, ISSN 1746-0913, 02/2015, Volume 10, Issue 2, pp. 147 - 150
microbiota | Crohn's disease | steroids | Mycobacterium paratuberculosis | Dietzia | Johne's disease | MYCOBACTERIUM-PARATUBERCULOSIS | CATTLE | MICROBIOLOGY | AVIUM SUBSPECIES PARATUBERCULOSIS | CULTURE | ANTIMYCOBACTERIAL THERAPY | MAP
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10. Full Text Microbial manipulation as primary therapy for Crohn's disease
by Longman, Randy S and Swaminath, Arun
World Journal of Gastroenterology, ISSN 1007-9327, 03/2013, Volume 19, Issue 10, pp. 1513 - 1516
While antimicrobials are clinically effective in preventing post-operative recurrence, the role for antibiotics in primary therapy for Crohn's disease (CD)... 
Inflammatory bowel disease | Rifaximin | Microbiome | CLARITHROMYCIN | ANTIMYCOBACTERIAL THERAPY | DOUBLE-BLIND | CLOFAZIMINE | PLACEBO-CONTROLLED TRIAL | GASTROENTEROLOGY & HEPATOLOGY | INFLAMMATORY BOWEL DISEASES | ANTIBIOTIC-THERAPY | Severity of Illness Index | Humans | Colon - drug effects | Anti-Infective Agents - therapeutic use | Colon - immunology | Treatment Outcome | Crohn Disease - immunology | Remission Induction | Multicenter Studies as Topic | Rifamycins - therapeutic use | Crohn Disease - drug therapy | Crohn Disease - diagnosis | Crohn Disease - microbiology | Colon - microbiology | Clinical Trials, Phase II as Topic | Index Medicus | Field Of Vision
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11. Full Text Resolution of crohn's disease and complex regional pain syndrome following treatment of paratuberculosis
by Kuenstner, J. Todd and Chamberlin, William and Naser, Saleh A and Collins, Michael T and Dow, Coad Thomas and Aitken, John M and Weg, Stuart and Telega, Grzegorz and John, Kuruvilla and Haas, David and Eckstein, Torsten M and Kali, Maher and Welch, Christine and Petrie, Thomas
World Journal of Gastroenterology, ISSN 1007-9327, 04/2015, Volume 21, Issue 13, pp. 4048 - 4062
A cohort of family members with various chronic diseases including Crohn's disease, asthma, complex regional pain syndrome, hypothyroidism, type 1 diabetes... 
Lymphangiomatosis | Crohn's disease | Cure | Complex regional pain syndrome | Mycobacterium avium paratuberculosis | VITAMIN-D | TYPE-1 DIABETES-MELLITUS | JOHNES-DISEASE | AVIUM SUBSPECIES PARATUBERCULOSIS | ULTRAVIOLET-LIGHT | ANTIMYCOBACTERIAL THERAPY | INFLAMMATORY-BOWEL-DISEASE | MYCOBACTERIUM-AVIUM | PULMONARY TUBERCULOSIS | ANTIGEN-PRESENTING CELLS | GASTROENTEROLOGY & HEPATOLOGY | Paratuberculosis - microbiology | Humans | Male | Paratuberculosis - transmission | Complex Regional Pain Syndromes - diagnosis | Young Adult | Complex Regional Pain Syndromes - microbiology | Colonoscopy | Crohn Disease - diagnosis | Adult | Bacteriological Techniques | Crohn Disease - microbiology | Female | Child | Mycobacterium avium subsp. paratuberculosis - radiation effects | Paratuberculosis - diagnosis | Antitubercular Agents - therapeutic use | Mycobacterium avium subsp. paratuberculosis - isolation & purification | Treatment Outcome | Combined Modality Therapy | Mycobacterium avium subsp. paratuberculosis - drug effects | Remission Induction | Ultraviolet Therapy - methods | Crohn Disease - therapy | Complex Regional Pain Syndromes - therapy | Biopsy | Paratuberculosis - therapy | Index Medicus | Case Report | Crohn’s disease
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12. Full Text Potential applications of lactic acid bacteria and bacteriocins in anti-mycobacterial therapy
by Sivaraj, Anbarasu and Sundar, Revathy and Manikkam, Radhakrishnan and Parthasarathy, Krupakar and Rani, Uma and Kumar, Vanaja
Asian Pacific Journal of Tropical Medicine, ISSN 1995-7645, 08/2018, Volume 11, Issue 8, pp. 453 - 459
Tuberculosis (TB) is a communicable disease caused by Mycobacterium tuberculosis (M. tuberculosis). WHO estimated that 10.4 million new (incident) TB cases... 
Hybrid bacteriocin | Antimycobacterial peptides | Lactic acid bacteria | Tuberculosis | Immunomodulation | Bacteriocin | PEDIOCIN-LIKE BACTERIOCINS | IFN-GAMMA | PROBIOTICS | ANTIMICROBIAL PEPTIDES | TROPICAL MEDICINE | NISIN | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | PRECURSOR LIPID II | CHEMICAL-SYNTHESIS | MYCOBACTERIUM-BOVIS | LACTOCOCCUS-LACTIS
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13. Full Text Inhaled Pyrazinoic Acid Esters for the Treatment of Tuberculosis
by Young, E F and Perkowski, E and Malik, S and Hayden, J D and Durham, P G and Zhong, L and Welch, J T and Braunstein, Miriam S and Hickey, Anthony J
Pharmaceutical Research, ISSN 0724-8741, 10/2016, Volume 33, Issue 10, pp. 2495 - 2505
Analog development of existing drugs and direct drug delivery to the lungs by inhalation as treatments for multiple and extensively drug resistant (MDR and... 
Biochemistry, general | Biomedical Engineering | Biomedicine | Pharmacy | tuberculosis | Medical Law | pyrazinoic acid | Pharmacology/Toxicology | inhaled therapy | pyrazinoic acid esters | TB drugs | PYRAZINAMIDE RESISTANCE | ANTITUBERCULOSIS DRUGS | SUSCEPTIBILITY | CHEMISTRY, MULTIDISCIPLINARY | IN-VITRO | THERAPY | STERILIZING ACTIVITY | RESISTANT MYCOBACTERIUM-TUBERCULOSIS | VITRO ANTIMYCOBACTERIAL ACTIVITY | PHARMACOLOGY & PHARMACY | INFECTION | GUINEA-PIG MODEL | Guinea Pigs | Pyrazinamide - analogs & derivatives | Administration, Inhalation | Esters | Male | Treatment Outcome | Mycobacterium tuberculosis - drug effects | Tuberculosis, Multidrug-Resistant - metabolism | Microbial Sensitivity Tests | Animals | Tuberculosis - drug therapy | Mycobacterium tuberculosis - physiology | Aerosols | Antitubercular Agents - administration & dosage | Tuberculosis - metabolism | Pyrazinamide - administration & dosage | Tuberculosis, Multidrug-Resistant - drug therapy | Drugs | Drug delivery systems | Tuberculosis | Analysis | Drug resistance | Drug therapy | Vehicles | Lungs | Index Medicus
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14. Full Text Pharmacokinetics of the first-line antituberculosis drugs in Ghanaian children with tuberculosis with or without HIV coinfection
by Antwi, Sampson and Yang, Hongmei and Enimil, Anthony and Sarfo, Anima M and Gillani, Fizza S and Ansong, Daniel and Dompreh, Albert and Orstin, Antoinette and Opoku, Theresa and Bosomtwe, Dennis and Wiesner, Lubbe and Norman, Jennifer and Peloquin, Charles A and Kwara, Awewura
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 02/2017, Volume 61, Issue 2, p. AAC.01701-16
Although human immunodeficiency virus (HIV) coinfection is the most important risk factor for a poor antituberculosis (anti-TB) treatment response, its effect... 
Tuberculosis | Children | Human immunodeficiency virus | First-line anti-TB drugs | Pharmacokinetics | SOUTH-AFRICA | CHILDHOOD TUBERCULOSIS | IMMUNODEFICIENCY-VIRUS-INFECTION | COTE-DIVOIRE | TREATMENT OUTCOMES | tuberculosis | MICROBIOLOGY | CULTURE-CONFIRMED TUBERCULOSIS | SERUM CONCENTRATIONS | children | CLINICAL PRESENTATION | ANTIMYCOBACTERIAL DRUGS | human immunodeficiency virus | pharmacokinetics | PULMONARY TUBERCULOSIS | PHARMACOLOGY & PHARMACY | first-line anti-TB drugs | Ethambutol - blood | Antitubercular Agents - adverse effects | Rifampin - pharmacokinetics | Rifampin - blood | Coinfection - drug therapy | Isoniazid - pharmacokinetics | Humans | Pyrazinamide - pharmacokinetics | AIDS-Related Opportunistic Infections - drug therapy | Isoniazid - blood | Child, Preschool | Ethambutol - pharmacokinetics | Male | Pyrazinamide - blood | Antitubercular Agents - blood | Tuberculosis - virology | Antitubercular Agents - pharmacokinetics | Tuberculosis - drug therapy | Female | HIV Infections - drug therapy | Child | Antitubercular Agents - therapeutic use | Index Medicus
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15. Full Text Synthesis and in vitro biological evaluation of 2-(phenylcarbamoyl)phenyl 4-substituted benzoates
by Krátký, Martin and Bősze, Szilvia and Baranyai, Zsuzsa and Szabó, Ildikó and Stolaříková, Jiřina and Paraskevopoulos, Georgios and Vinšová, Jarmila
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 02/2015, Volume 23, Issue 4, pp. 868 - 875
Based on the previously described antimicrobial activity of salicylanilide derivatives, we designed and synthesized novel 2-(phenylcarbamoyl)phenyl... 
Benzoate | Ester | Antimicrobial activity | Multidrug-resistant tuberculosis | Cytostasis | Mycobacterium tuberculosis | In vitro activity | Nontuberculous mycobacteria | Cytotoxicity | Salicylanilide | MYCOBACTERIUM-TUBERCULOSIS | ANTIMYCOBACTERIAL ACTIVITY | CHEMISTRY, MEDICINAL | TYROSINE KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | IDENTIFICATION | DISCOVERY | SALICYLANILIDES | GROWTH-FACTOR RECEPTOR | INHIBITORS | DERIVATIVES | Antifungal Agents - pharmacology | Fungi - drug effects | Bacterial Infections - drug therapy | Benzoates - chemistry | Humans | Bacteria - drug effects | Antifungal Agents - chemical synthesis | Antifungal Agents - chemistry | Benzoates - chemical synthesis | Mycobacterium tuberculosis - drug effects | Anti-Bacterial Agents - chemical synthesis | Mycobacterium - drug effects | Mycobacterium Infections - drug therapy | Anti-Bacterial Agents - chemistry | Tuberculosis - drug therapy | Mycoses - drug therapy | Benzoates - pharmacology | Anti-Bacterial Agents - pharmacology | Tuberculosis, Multidrug-Resistant - drug therapy | Index Medicus
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