X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (99211) 99211
Publication (9295) 9295
Book Review (658) 658
Book Chapter (448) 448
Conference Proceeding (138) 138
Dissertation (102) 102
Book / eBook (74) 74
Paper (28) 28
Data Set (21) 21
Web Resource (12) 12
Newspaper Article (10) 10
Government Document (8) 8
Magazine Article (8) 8
Journal / eJournal (2) 2
Reference (1) 1
Trade Publication Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (61579) 61579
index medicus (52255) 52255
animals (43949) 43949
mice (32611) 32611
cell line, tumor (30412) 30412
cancer (27633) 27633
oncology (26778) 26778
antineoplastic agents - pharmacology (23122) 23122
antitumor-activity (21417) 21417
xenograft model antitumor assays (20556) 20556
female (20474) 20474
drug screening assays, antitumor (20238) 20238
apoptosis (18929) 18929
chemistry, medicinal (16097) 16097
pharmacology & pharmacy (15124) 15124
cell proliferation - drug effects (14953) 14953
male (13479) 13479
biochemistry & molecular biology (12912) 12912
antineoplastic agents - chemistry (12621) 12621
antitumor activity (12284) 12284
mice, nude (12281) 12281
tumors (11985) 11985
apoptosis - drug effects (11221) 11221
structure-activity relationship (10825) 10825
cytotoxicity (10647) 10647
analysis (9983) 9983
expression (9623) 9623
molecular structure (9046) 9046
chemotherapy (9039) 9039
in-vitro (9014) 9014
antineoplastic agents - chemical synthesis (8894) 8894
dose-response relationship, drug (8727) 8727
chemistry, organic (8555) 8555
tumor cells, cultured (8448) 8448
care and treatment (7985) 7985
cell survival - drug effects (7722) 7722
mice, inbred balb c (7546) 7546
cells (7424) 7424
research (7361) 7361
antitumor agents (7322) 7322
article (7076) 7076
chemistry, multidisciplinary (7019) 7019
antitumor (6952) 6952
proteins (6936) 6936
derivatives (6641) 6641
cell biology (6377) 6377
inhibition (6292) 6292
anticancer properties (6139) 6139
growth (6117) 6117
antineoplastic agents - therapeutic use (6050) 6050
in-vivo (5934) 5934
health aspects (5923) 5923
metastasis (5865) 5865
activation (5624) 5624
therapy (5587) 5587
breast cancer (5518) 5518
cell proliferation (5404) 5404
immunotherapy (5334) 5334
neoplasms - drug therapy (5193) 5193
cancer therapies (5159) 5159
medicine, research & experimental (5136) 5136
gene expression (4833) 4833
drugs (4618) 4618
toxicity (4582) 4582
cell cycle (4511) 4511
immunology (4498) 4498
kinases (4433) 4433
inhibitors (4420) 4420
antineoplastic agents (4368) 4368
antineoplastic agents, phytogenic - pharmacology (4347) 4347
signal transduction - drug effects (4200) 4200
signal transduction (4193) 4193
breast-cancer (4116) 4116
angiogenesis (4100) 4100
medicine (3977) 3977
middle aged (3880) 3880
rats (3802) 3802
multidisciplinary sciences (3779) 3779
research article (3744) 3744
flow cytometry (3715) 3715
phosphorylation (3617) 3617
disease models, animal (3591) 3591
antimitotic agents (3589) 3589
dna (3546) 3546
nanoparticles (3506) 3506
carcinoma (3488) 3488
models, molecular (3402) 3402
mice, scid (3397) 3397
chemistry (3366) 3366
biotechnology & applied microbiology (3360) 3360
ligands (3356) 3356
drug synergism (3330) 3330
inhibitory concentration 50 (3294) 3294
resistance (3278) 3278
genetic aspects (3264) 3264
drug delivery systems (3256) 3256
melanoma (3251) 3251
chemistry, inorganic & nuclear (3236) 3236
xenografts (3221) 3221
drug design (3204) 3204
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (39) 39
Collection Dvlpm't (Acquisitions) - Vendor file (9) 9
Collection Dvlpm't (Acquisitions) - Closed Orders (4) 4
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (4) 4
Online Resources - Online (2) 2
UofT at Mississauga - Stacks (2) 2
Scarborough Hospital - Birchmount (1) 1
St. Michael's Hospital - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (98692) 98692
Japanese (1479) 1479
Chinese (665) 665
German (190) 190
Russian (135) 135
French (119) 119
Spanish (96) 96
Korean (78) 78
Polish (41) 41
Portuguese (35) 35
Croatian (11) 11
Hungarian (8) 8
Czech (5) 5
Italian (4) 4
Slovak (4) 4
Slovenian (3) 3
Dutch (2) 2
Turkish (2) 2
Bosnian (1) 1
Bulgarian (1) 1
Catalan (1) 1
Indonesian (1) 1
Malay (1) 1
Serbian (1) 1
Ukrainian (1) 1
Welsh (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 10/2016, Volume 163, pp. 88 - 97
Journal Article
Journal Article
Journal Article
Biomaterials, ISSN 0142-9612, 2009, Volume 31, Issue 10, pp. 2882 - 2892
Journal Article
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2007, Volume 50, Issue 9, pp. 2185 - 2193
Journal Article
Drug Design, Development and Therapy, ISSN 1177-8881, 06/2017, Volume 11, pp. 1891 - 1904
This study deals with the design and synthesis of a series of novel 4-methoxy-substituted and 5-methyl-substituted (3' ,4' )-(-)- -khellactones. The newly... 
4-methoxy-substituted and 5-methyl-substituted (3′S,4′S)-(-)-cis-khellactones | Synthesis | Apoptosis | Cytotoxic activity | Antineoplastic Agents, Phytogenic - chemical synthesis | Magnetic Resonance Spectroscopy | Apoptosis - drug effects | Humans | Structure-Activity Relationship | Membrane Potential, Mitochondrial - drug effects | Coumarins - pharmacology | Tetrazolium Salts | Tandem Mass Spectrometry | Signal Transduction - drug effects | Coumarins - chemical synthesis | Thiazoles | Cell Line, Tumor | Caspases - drug effects | Enzyme Activation | Antineoplastic Agents, Phytogenic - pharmacology | Drug Screening Assays, Antitumor | Drugs | Care and treatment | Usage | Structure-activity relationship (Pharmacology) | Development and progression | Hepatoma | Structure-activity relationships | Health aspects | Testing | Lactones | Nuclear magnetic resonance--NMR | Toxicity | Liver | Staining | Cytotoxicity | Propidium iodide | Caspase-3 | Anticancer properties | Substitutes | Mitochondria | Membrane potential | Colon | Gastric cancer | Magnetic induction | Iodides | Caspase | Data processing | Mass spectroscopy | Derivatives | Caspase-9 | Annexin V | Mass spectrometry | Cancer | Values | Cancer therapies | Chinese medicine | Acquired immune deficiency syndrome--AIDS | Energy dissipation | Human immunodeficiency virus--HIV | Pharmaceutical sciences | Glycoproteins | Chromatography | Chemistry | Chemotherapy | Potassium | synthesis | 4-methoxy-substituted and 5-methyl-substituted (3'S | apoptosis | cytotoxic activity | 4'S)-(-)-cis-khellactones
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 06/2013, Volume 64, pp. 81 - 89
A novel copper(I) Schiff base complex has been synthesized and fully characterized by spectral, analytical and structural modes. Single crystal X-ray... 
Cytotoxicity | Antioxidant | DNA interaction | Copper(I) complex | Crystal structure | ANTIOXIDANT ACTIVITY | CHEMISTRY, MEDICINAL | TRANSITION-METAL-COMPLEXES | MEDICINAL INORGANIC-CHEMISTRY | CRYSTAL-STRUCTURE | CU(II) COMPLEXES | CO(II) | NI(II) | PLATINUM COMPLEXES | IN-VITRO | RUTHENIUM COMPLEXES | Free Radical Scavengers - pharmacology | Free Radical Scavengers - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Crystallography, X-Ray | Structure-Activity Relationship | Schiff Bases - pharmacology | Dose-Response Relationship, Drug | Copper - chemistry | MCF-7 Cells | Cattle | Drug Design | Free Radical Scavengers - chemical synthesis | Schiff Bases - chemical synthesis | Antineoplastic Agents - pharmacology | Molecular Structure | Binding Sites - drug effects | DNA - drug effects | Cell Survival - drug effects | Models, Molecular | Antineoplastic Agents - chemistry | Coordination Complexes - chemistry | DNA Cleavage - drug effects | DNA - chemistry | Animals | Organometallic Compounds - chemical synthesis | Schiff Bases - chemistry | Cell Line, Tumor | Ligands | Organometallic Compounds - chemistry | Cell Proliferation - drug effects | HeLa Cells | Organometallic Compounds - pharmacology | Drug Screening Assays, Antitumor | Schiff bases | Care and treatment | DNA | Genetic research | Chemical properties | Comparative analysis | DNA-ligand interactions | Cancer
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2016, Volume 121, pp. 410 - 421
Journal Article
02/2015, Volume 5, Issue 26, pp. 239 - 2338
The non-communicable disease, cancer, is one of the major causes of death across the world and is forecast to increase by 75% to reach close to 25 million... 
Journal Article
International Journal of Cancer, ISSN 0020-7136, 07/2018, Volume 143, Issue 2, pp. 419 - 429
Aneustat (OMN54) is a multivalent, botanical anticancer candidate therapeutic. A recent Phase‐I clinical trial has indicated that it is well tolerated by... 
immunomodulation | first‐generation PDX model | Aneustat | aerobic glycolysis | lactic acid secretion | first-generation PDX model | LACTIC-ACID | TARGET | PROGNOSIS | BALANCE | NK CELLS | GENE | ONCOLOGY | IMMUNE SURVEILLANCE | MICE | SUPPRESSOR-CELLS | T-CELLS | Small Molecule Libraries - pharmacology | Aerobiosis | Small Molecule Libraries - administration & dosage | Humans | Lactic Acid - metabolism | Immunologic Factors - administration & dosage | Male | Macrophages - cytology | Glycolysis - drug effects | Prostatic Neoplasms - immunology | Xenograft Model Antitumor Assays | Animals | Prostatic Neoplasms - genetics | Cell Differentiation - drug effects | Cell Line, Tumor | Macrophages - drug effects | RAW 264.7 Cells | Cell Proliferation - drug effects | Mice | Gene Expression Regulation, Neoplastic - drug effects | Immunologic Factors - pharmacology | Prostatic Neoplasms - drug therapy | Glucose metabolism | Killer cells | Immune response | Analysis | Immunotherapy | Lactic acid | Diagnosis | Macrophages | Gene expression | Prostate cancer | Cancer | Cell proliferation | Animal models | Phenotypes | Immunomodulation | Secretion | CD8 antigen | Xenotransplantation | Acidification | Cytotoxicity | Lymphocytes T | Patients | Immunosuppression | Rodents | Xenografts | Glycolysis | In vivo methods and tests | Differentiation | Prostate | Immune system | Cancer Therapy and Prevention
Journal Article
Journal Article