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Journal Article
Phytotherapy Research, ISSN 0951-418X, 09/2019, Volume 33, Issue 9, pp. 2141 - 2151
Journal Article
Chemical and Pharmaceutical Bulletin, ISSN 0009-2363, 2016, Volume 64, Issue 2, pp. 128 - 134
As angiogenesis is critical for tumor growth and metastasis, potent and selective anti-angiogenic agents with novel modes of action are highly needed for... 
Journal Article
mAbs, ISSN 1942-0862, 09/2014, Volume 6, Issue 5, pp. 1314 - 1326
Ovarian cancer has the highest mortality rate among gynecologic malignancies. The monoclonal antibody 12G4 specifically recognizes the human Müllerian... 
ovarian carcinoma | GCT | MISRII | therapeutic antibodies | immunotherapy | MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | GRANULOSA-CELL TUMORS | LINES | ENDOCYTIC REGULATION | HORMONE | PATHWAY | IN-VIVO | GROWTH | MONOCLONAL-ANTIBODIES | ANTIGEN | Immunohistochemistry | Immunotherapy - methods | Receptors, Transforming Growth Factor beta - immunology | Apoptosis - drug effects | Humans | Antibody-Dependent Cell Cytotoxicity - immunology | Neoplasms, Glandular and Epithelial - metabolism | Antibodies, Monoclonal - therapeutic use | Granulosa Cell Tumor - immunology | Neoplasms, Glandular and Epithelial - immunology | Female | Ovarian Neoplasms - metabolism | Receptors, Peptide - immunology | Antibodies, Monoclonal - immunology | Neoplasms, Glandular and Epithelial - therapy | Receptors, Peptide - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | Apoptosis - immunology | Receptors, Transforming Growth Factor beta - antagonists & inhibitors | Receptors, Transforming Growth Factor beta - metabolism | Mice, Nude | Granulosa Cell Tumor - metabolism | Carcinoma, Ovarian Epithelial | Cell Line, Tumor | Ovarian Neoplasms - therapy | Antibody-Dependent Cell Cytotoxicity - drug effects | Microscopy, Fluorescence | Granulosa Cell Tumor - therapy | Ovarian Neoplasms - immunology | Receptors, Peptide - metabolism
Journal Article
Journal Article
Pharmaceutical Chemistry Journal, ISSN 0091-150X, 04/2018, Volume 52, Issue 1, pp. 57 - 62
We present here a review of published data mostly from the last 10 years on the antitumor activity of substances from the fungus Ganoderma lucidum. Its main... 
polysaccharides | Ganoderma lucidum | antitumor activity | triterpenes | CHEMISTRY, MEDICINAL | METASTASIS | CYCLE ARREST | MEDIATED APOPTOSIS | INDUCTION | COLON-CANCER CELLS | INHIBITION | HUMAN HEPATOMA-CELLS | IN-VIVO | PHARMACOLOGY & PHARMACY | TRITERPENE-ENRICHED EXTRACTS | Fungi | Medical research | Saponins | Ionizing radiation | Medicine, Experimental | Glycoproteins | Metastasis | Terpenes
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 05/2014, Volume 306, Issue 9, pp. G759 - G768
Substance P (SP) promotes cholangiocyte growth during cholestasis by activating its receptor, NK1R. SP is a proteolytic product of tachykinin (Tac1) and is... 
Biliary cancer | Autocrine | Neuroendocrine | VEGF | Sensory innervation | ACTIVATION | PHYSIOLOGY | neuroendocrine | REDUCES CHOLANGIOCYTE PROLIFERATION | ALPHA | CD10 EXPRESSION | FACTOR RECEPTOR | CANCER | DUCT-LIGATED MICE | LIVER | CARCINOMAS | sensory innervation | GASTROENTEROLOGY & HEPATOLOGY | biliary cancer | autocrine | CELL-LINE | Up-Regulation | Humans | Gene Expression Regulation, Neoplastic | Male | Vascular Endothelial Growth Factor A - metabolism | Bile Duct Neoplasms - enzymology | Bile Ducts, Intrahepatic - drug effects | Dose-Response Relationship, Drug | Neurokinin-1 Receptor Antagonists - pharmacology | Transfection | Time Factors | Neprilysin - genetics | Receptors, Neurokinin-1 - metabolism | Bile Duct Neoplasms - genetics | Bile Duct Neoplasms - drug therapy | Cholangiocarcinoma - enzymology | Bile Ducts, Intrahepatic - pathology | Neprilysin - metabolism | Tumor Burden | Bile Ducts, Intrahepatic - enzymology | Gene Expression Regulation, Enzymologic | Xenograft Model Antitumor Assays | Cholangiocarcinoma - pathology | Animals | Cholangiocarcinoma - drug therapy | Mice, Nude | Cell Line, Tumor | Cholangiocarcinoma - genetics | Substance P - metabolism | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Bile Duct Neoplasms - pathology | Keratin-19 - metabolism | Proliferating Cell Nuclear Antigen - metabolism | Protein research | Carcinoma | Proteases | Oncology, Experimental | Development and progression | Genetic aspects | Research | Gene expression | Health aspects | Membrane proteins | Cancer | Liver and Biliary Tract
Journal Article
Frontiers in Pharmacology, ISSN 1663-9812, 2019, Volume 10, p. 266
Phellinus igniarius (P. igniarius) is a medicinal fungus that is widely used in East Asia for the adjuvant treatment of cancer. To elucidate the antitumor... 
Mitochondrial apoptosis pathway | Effective substances | Network pharmacology | Phytochemistry | Antitumor | Phellinus igniarius | APOPTOSIS | MEDICINAL MUSHROOMS | antitumor | network pharmacology | mitochondrial apoptosis pathway | GROWTH | PHARMACOLOGY & PHARMACY | effective substances | CANCER | phytochemistry
Journal Article
Bulletin of Experimental Biology and Medicine, ISSN 0007-4888, 2/2019, Volume 166, Issue 4, pp. 456 - 460
We performed an in vivo comparative study of activity of three substances of the nitrosourea group produced in Russia. All substances demonstrated high... 
Biomedicine, general | Pathology | Biomedicine | antitumor activity | tumor | Internal Medicine | nitrosourea-based substances | Laboratory Medicine | Cell Biology | MEDICINE, RESEARCH & EXPERIMENTAL | Mice | Lung cancer | Analysis | Cervical cancer | Tumors
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2015, Volume 112, Issue 32, pp. E4418 - E4427
Journal Article