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1. Full Text Loss of WD2 subdomain of Apaf-1 forms an apoptosome structure which blocks activation of caspase-3 and caspase-9
by Noori, Ali-Reza and Tashakor, Amin and Nikkhah, Maryam and Eriksson, Leif A and Hosseinkhani, Saman and Fearnhead, Howard O
Biochimie, ISSN 0300-9084, 01/2021, Volume 180, pp. 23 - 29
Split-luciferase | Cell-free | Apoptosome | Apaf-1 | Apoptosis | Index Medicus
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2. Full Text Apoptosome formation upon overexpression of native and truncated Apaf-1 in cell-free and cell-based systems
by Noori, Ali Reza and Hosseini, Elaheh Sadat and Nikkhah, Maryam and Hosseinkhani, Saman
Archives of biochemistry and biophysics, ISSN 0003-9861, 03/2018, Volume 642, pp. 46 - 51
Split-luciferase | Cell death | Cell-free system | Truncated Apaf-1 | Apoptosome | Apaf-1 | Apoptosis | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Index Medicus
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3. Full Text Melittin suppresses growth and induces apoptosis of non-small-cell lung cancer cells via down-regulation of TGF-β-mediated ERK signal pathway
by Yu, Renzhi and Wang, Miao and Wang, Minghuan and Han, Lei
Brazilian journal of medical and biological research, ISSN 0100-879X, 2020, Volume 54, Issue 2, pp. e9017 - e9017
Signal transduction | Small cell lung carcinoma | Apaf-1 protein | Lung cancer | Non-small cell lung carcinoma | Extracellular signal-regulated kinase | Gene expression | Caspase-3 | APAF-1 gene | Cell migration | Apoptosis | Index Medicus
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4. Full Text Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition
by Xu, Wanfeng and Che, Yuan and Zhang, Quan and Huang, Hai and Ding, Chujie and Wang, Yun and Wang, Guangji and Cao, Lijuan and Hao, Haiping
Cell metabolism, 12/2020
Index Medicus
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5. Full Text Cdc6: A trifunctional AAA+ ATPase that plays a central role in controlling the G1-S transition and cell survival
by Okayama, Hiroto
Journal of biochemistry (Tokyo), ISSN 0021-924X, 10/2012, Volume 152, Issue 4, pp. 297 - 303
Apaf-1 | ROCK | Cdc6 | p27 | Cdk2
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6. Full Text 凋亡调节蛋白Bcl-2和Apaf-1在乳腺癌中的表达及临床意义
by 刘卓 and 李晓凤 and 张美云
包头医学院学报, ISSN 1006-740X, 2017, Volume 33, Issue 11, pp. 78 - 80
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7. Full Text Epigenetic Regulation of APAF-1 Through DNA Methylation in Pancreatic Cancer
by Lukosiute-Urboniene, Ausra and Mazeike, Augustina and Kazokaite, Mintaute and Silkuniene, Giedre and Silkunas, Mantas and Barauskas, Vidmantas and Barauskas, Giedrius and Gulbinas, Antanas and Dauksa, Albertas and Dambrauskas, Zilvinas
Anticancer research, ISSN 0250-7005, 07/2020, Volume 40, Issue 7, pp. 3765 - 3779
Life Sciences & Biomedicine | Oncology | Science & Technology | Adenocarcinoma | Peptidase | Deactivation | Growth rate | Immunoblotting | Cell viability | mRNA | Tumor cell lines | Inactivation | Polymerase chain reaction | Proteins | Demethylation | Apaf-1 protein | Pancreatic cancer | DNA methylation | Methylation | APAF-1 gene | Deoxyribonucleic acid--DNA | Apoptosis | Cancer | 5-aza-2'-deoxycytidine | Index Medicus
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8. Full Text BIOCHEMICAL PATHWAYS OF CASPASE ACTIVATION DURING APOPTOSIS
by Budihardjo, Imawati and Oliver, Holt and Lutter, Michael and Luo, Xu and Wang, Xiaodong
Annual review of cell and developmental biology, ISSN 1081-0706, 11/1999, Volume 15, Issue 1, pp. 269 - 290
Bcl-2 | cytochrome | cell surface death receptor | Apaf-1 | c | mitochondria | Cell surface death receptor | Cytochrome c | Mitochondria | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Animals | Caspases - metabolism | Humans | Receptors, Cell Surface - metabolism | Mitochondria - metabolism | Enzyme Activation | Apoptosis | inhibitor of apoptosis protein | caspase-8 | cytochrome c | Apaf-1 protein | caspase-9 | Index Medicus
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9. Full Text MiR-155 inhibits the sensitivity of lung cancer cells to cisplatin via negative regulation of Apaf-1 expression
by Zang, Y.-S and Zhong, Y.-F and Fang, Z and Li, B and An, J
Cancer gene therapy, ISSN 0929-1903, 11/2012, Volume 19, Issue 11, pp. 773 - 778
lung cancer | apoptosis | Apaf-1 | cisplatin | DNA damage | miR-155 | Life Sciences & Biomedicine | Oncology | Genetics & Heredity | Biotechnology & Applied Microbiology | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | RNA, Small Interfering - genetics | Caspase 9 - genetics | Caspase 9 - metabolism | Humans | Lung Neoplasms - metabolism | RNA, Messenger - genetics | Gene Expression Regulation, Neoplastic | Gene Silencing | Lung Neoplasms - pathology | MicroRNAs - metabolism | Cisplatin - pharmacology | Apoptotic Protease-Activating Factor 1 - genetics | RNA, Messenger - metabolism | Comet Assay | Apoptotic Protease-Activating Factor 1 - metabolism | Transfection | Cell Line, Tumor | Antineoplastic Agents - pharmacology | MicroRNAs - genetics | DNA Damage | Apoptosis | Drug Resistance, Neoplasm - drug effects | RNA, Small Interfering - metabolism | Usage | Control | Care and treatment | Lung cancer | Physiological aspects | Cellular signal transduction | Research | Gene expression | Health aspects | Cisplatin | Index Medicus | Apaf-1 protein
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10. Full Text New insights into apoptosome structure and function
by Dorstyn, Loretta and Akey, Christopher W and Kumar, Sharad
Cell death and differentiation, ISSN 1350-9047, 07/2018, Volume 25, Issue 7, pp. 1194 - 1208
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cytochrome c | Interfaces | Caspase | Cell death | Apaf-1 protein | Structure-function relationships | Review
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11. Up-regulated miR-221 expression as a molecular diagnostic marker in laryngeal squamous cell carcinoma and its correlation with Apaf-1 expression
by Hussein, Samia and Mosaad, Hala and Rashed, Hayam E and El-Anwar, Mohammad W
Cancer biomarkers : section A of Disease markers, ISSN 1574-0153, 2017, Volume 19, Issue 3, pp. 279 - 287
Laryngeal squamous cell carcinoma | miR-221 | Apaf-1 | Life Sciences & Biomedicine | Oncology | Science & Technology | Up-Regulation | Prognosis | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Male | MicroRNAs - metabolism | Apoptotic Protease-Activating Factor 1 - genetics | Biomarkers, Tumor | Apoptotic Protease-Activating Factor 1 - metabolism | Laryngeal Neoplasms - pathology | Carcinoma, Squamous Cell - diagnosis | Adult | Apoptotic Protease-Activating Factor 1 - biosynthesis | Female | Aged | Laryngeal Neoplasms - diagnosis | Immunohistochemistry | Squamous cell carcinoma | Correlation | Apaf-1 protein | Diagnostic systems | Metastasis | Gene expression | Tissues | APAF-1 gene | Lymph nodes | Metastases | Apoptosis
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