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1. Full Text APOBEC3G DNA deaminase acts processively 3′ → 5′ on single-stranded DNA
by Calabrese, Peter and Chelico, Linda and Pham, Phuong and Goodman, Myron F
Nature structural & molecular biology, ISSN 1545-9993, 05/2006, Volume 13, Issue 5, pp. 392 - 399
Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Line | Cytidine Deaminase | DNA, Single-Stranded - metabolism | Repressor Proteins - genetics | Substrate Specificity | Mutation - genetics | RNA - genetics | Spodoptera | DNA, Single-Stranded - genetics | Nucleoside Deaminases - metabolism | APOBEC-3G Deaminase | Nucleoside Deaminases - genetics | Animals | Amination | Base Sequence | Protein Binding | Catalysis | Repressor Proteins - metabolism | Physiological aspects | Enzymes | Genetic aspects | Research | Gene expression | DNA-ligand interactions | Human immunodeficiency virus | HIV | Molecular biology | Deoxyribonucleic acid | DNA | Index Medicus
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2. Full Text The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA
by Yang, Bin and Arunachalam, Shyamala C and Pomerantz, Roger J and Gao, Ling and Zhang, Hui and Zhang, Chune
Nature (London), ISSN 0028-0836, 07/2003, Volume 424, Issue 6944, pp. 94 - 98
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Cell Line | Cytidine Deaminase | DNA, Viral - biosynthesis | Humans | Repressor Proteins | Mutagenesis - genetics | vif Gene Products, Human Immunodeficiency Virus | Gene Products, vif - metabolism | HIV-1 - genetics | Nucleoside Deaminases | Proteins - genetics | APOBEC-3G Deaminase | Point Mutation - genetics | HIV-1 - growth & development | HIV-1 - physiology | Proteins - metabolism | Virus Replication | Gene Products, vif - genetics | Transcription, Genetic - genetics | DNA, Viral - genetics | Gene Products, vif - deficiency | Serial Passage | Mutation | Human immunodeficiency virus | HIV | Deoxyribonucleic acid | DNA | Index Medicus
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3. Full Text Biochemical analysis of hypermutation by the deoxycytidine deaminase APOBEC3A
by Love, Robin P and Xu, Huixin and Chelico, Linda
The Journal of biological chemistry, ISSN 0021-9258, 08/2012, Volume 287, Issue 36, pp. 30812 - 30822
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Cytoplasm - enzymology | Cytidine Deaminase - genetics | Humans | DNA, Viral - metabolism | Cell Nucleus - enzymology | Proteins - genetics | APOBEC-3G Deaminase | HIV-1 - physiology | Proteins - metabolism | Cell Nucleus - genetics | Cytidine Deaminase - metabolism | Cytoplasm - genetics | Mutation | Transcription, Genetic - genetics | DNA, Viral - genetics | Virus Replication - physiology | Index Medicus | Enzyme Mechanisms | Mutagenesis Mechanisms | DNA Deaminases | DNA and Chromosomes | Protein-DNA Interaction | HIV | DNA Repair | HIV Restriction Factor | Viral Immunology | DNA Transcription | Reverse Transcription
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4. Full Text Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G
by Chen, Kuan-Ming and Harjes, Elena and Gross, Phillip J and Fahmy, Amr and Lu, Yongjian and Shindo, Keisuke and Harris, Reuben S and Matsuo, Hiroshi
Nature (London), ISSN 0028-0836, 03/2008, Volume 452, Issue 7183, pp. 116 - 119
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Structure in molecular biology | Tridimensional structure | Molecular biophysics | Catalytic Domain | Protein Structure, Secondary | Zinc - metabolism | Cytidine Deaminase - genetics | DNA, Single-Stranded - metabolism | Humans | Models, Molecular | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | DNA, Single-Stranded - chemistry | DNA-Binding Proteins - metabolism | APOBEC-3G Deaminase | HIV-1 - physiology | Cytidine Deaminase - metabolism | Hydrophobic and Hydrophilic Interactions | Nuclear Magnetic Resonance, Biomolecular | Catalysis | Binding Sites | Cytidine Deaminase - chemistry | DNA polymerases | Physiological aspects | Genetic aspects | Research | Structure | HIV (Viruses) | Apolipoproteins | Health aspects | Proteins | Genetics | Human immunodeficiency virus--HIV | Deoxyribonucleic acid--DNA | Index Medicus
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5. Full Text APOBEC3G cytidine deaminase inhibits retrotransposition of endogenous retroviruses
by Heidmann, Thierry and Heidmann, Odile and Schwartz, Olivier and Delebecque, Frédéric and Ribet, David and Hance, Allan J and Esnault, Cécile and Dewannieux, Marie
Nature, ISSN 0028-0836, 01/2005, Volume 433, Issue 7024, pp. 430 - 433
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains | Biological and medical sciences | Microbiology | Virology | Cell Line | Virus Integration - genetics | Cytidine Deaminase - genetics | Humans | Repressor Proteins | Mutagenesis - genetics | Molecular Sequence Data | Endogenous Retroviruses - genetics | Nucleoside Deaminases | Retroelements - genetics | Proteins - genetics | APOBEC-3G Deaminase | Animals | Proteins - metabolism | Base Sequence | Cytidine Deaminase - metabolism | Mice | HeLa Cells | Genome | Proteins | Enzymes | Viruses | Human immunodeficiency virus | HIV | Genomics | Index Medicus | Life Sciences
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6. Full Text A Portable Hot Spot Recognition Loop Transfers Sequence Preferences from APOBEC Family Members to Activation-induced Cytidine Deaminase
by Rahul M. Kohli and Shaun R. Abrams and Kiran S. Gajula and Robert W. Maul and Patricia J. Gearhart and James T. Stivers
The Journal of biological chemistry, ISSN 0021-9258, 08/2009, Volume 284, Issue 34, pp. 22898 - 22904
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Amino Acid Sequence | Cytidine Deaminase - genetics | Escherichia coli - drug effects | Humans | Enzyme Inhibitors - pharmacology | Molecular Sequence Data | Sequence Homology, Amino Acid | APOBEC-3G Deaminase | Amino Acid Motifs - physiology | Cytosine Deaminase - metabolism | Escherichia coli - genetics | Cytidine Deaminase - metabolism | Cytosine Deaminase - chemistry | Mutation | Rifampin - pharmacology | Amino Acid Motifs - genetics | Drug Resistance, Bacterial - genetics | Cytidine Deaminase - chemistry | Cytosine Deaminase - genetics | Index Medicus | DNA | Repair, Recombination, and Chromosome Dynamics
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7. Full Text APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection
by Pion, Marjorie and Granelli-Piperno, Angela and Mangeat, Bastien and Stalder, Romaine and Correa, Rafael and Steinman, Ralph M and Piguet, Vincent
The Journal of experimental medicine, ISSN 0022-1007, 12/2006, Volume 203, Issue 13, pp. 2887 - 2893
Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Cytidine Deaminase | RNA, Small Interfering - genetics | Monocytes - cytology | Virus Replication - genetics | Humans | Molecular Sequence Data | Green Fluorescent Proteins - genetics | Nucleoside Deaminases - metabolism | Repressor Proteins - physiology | Cell Differentiation - genetics | Flow Cytometry | HIV-1 - growth & development | Transfection | Cytosine Deaminase - metabolism | Base Sequence | Dendritic Cells - drug effects | Cytosine Deaminase - physiology | Dendritic Cells - virology | Cytosine Deaminase - genetics | Dendritic Cells - metabolism | Repressor Proteins - metabolism | Carrier Proteins - physiology | Cell Line | Green Fluorescent Proteins - metabolism | Gene Expression | Nucleoside Deaminases - physiology | Viral Envelope Proteins - genetics | Jurkat Cells | Repressor Proteins - genetics | HIV-1 - genetics | Sequence Homology, Nucleic Acid | Membrane Glycoproteins - genetics | APOBEC-3G Deaminase | Carrier Proteins - genetics | Point Mutation | Nucleoside Deaminases - genetics | Carrier Proteins - metabolism | Cell Differentiation - drug effects | Lipopolysaccharides - pharmacology | HeLa Cells | DNA, Viral - genetics | Index Medicus
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8. Full Text Heat shock proteins stimulate APOBEC-3–mediated cytidine deamination in the hepatitis B virus
by Chen, Zhigang and Eggerman, Thomas L and Bocharov, Alexander V and Baranova, Irina N and Vishnyakova, Tatyana G and Kurlander, Roger and Patterson, Amy P
The Journal of biological chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 32, pp. 13459 - 13479
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Humans | Hepatocytes - metabolism | Carcinogenesis | Recombinant Fusion Proteins - metabolism | DNA, Recombinant - chemistry | RNA Interference | DNA Mutational Analysis | Minor Histocompatibility Antigens - genetics | HSP90 Heat-Shock Proteins - genetics | Cytidine Deaminase - chemistry | Hepatitis B virus - immunology | Peptide Fragments - genetics | APOBEC-3G Deaminase - chemistry | Recombinant Proteins - metabolism | Peptide Fragments - metabolism | APOBEC-3G Deaminase - genetics | Cytidine Deaminase - genetics | DNA, Viral - metabolism | Recombinant Proteins - chemistry | Mutation Rate | Recombinant Fusion Proteins - chemistry | Hepatocytes - immunology | Immunity, Innate | Hep G2 Cells | DNA, Viral - chemistry | Point Mutation | Minor Histocompatibility Antigens - metabolism | APOBEC-3G Deaminase - metabolism | Deamination | Mutagenesis | HSP90 Heat-Shock Proteins - antagonists & inhibitors | Peptide Fragments - agonists | Cytidine Deaminase - metabolism | Hepatitis B virus - genetics | HSP90 Heat-Shock Proteins - metabolism | Hepatocytes - virology | Cytidine - metabolism | DNA, Recombinant - metabolism | Hepatitis B virus - metabolism | Minor Histocompatibility Antigens - chemistry | Index Medicus | Molecular Bases of Disease | heat shock protein 90 (Hsp90) | hepatitis B virus (HBV, Hep B) | APOBEC-3G | cofactor | cancer | cytidine deaminase | mutagenesis
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9. Full Text The Activity Spectrum of Vif from Multiple HIV-1 Subtypes against APOBEC3G, APOBEC3F, and APOBEC3H
by Mawuena Binka and Marcel Ooms and Myeika Steward and Viviana Simon
Journal of Virology, ISSN 0022-538X, 01/2012, Volume 86, Issue 1, pp. 49 - 59
Life Sciences & Biomedicine | Science & Technology | Virology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Microbiology | Aminohydrolases - chemistry | Humans | Molecular Sequence Data | HIV Infections - enzymology | Phylogeny | vif Gene Products, Human Immunodeficiency Virus - genetics | Aminohydrolases - genetics | vif Gene Products, Human Immunodeficiency Virus - metabolism | Cytosine Deaminase - metabolism | HIV-1 - chemistry | Cytosine Deaminase - chemistry | Cytidine Deaminase - chemistry | Cytosine Deaminase - genetics | Amino Acid Sequence | Cell Line | HIV-1 - metabolism | Cytidine Deaminase - genetics | HIV Infections - genetics | HIV Infections - virology | vif Gene Products, Human Immunodeficiency Virus - chemistry | HIV-1 - genetics | HIV-1 - classification | APOBEC-3G Deaminase | Sequence Alignment | Cytidine Deaminase - metabolism | Protein Binding | Aminohydrolases - metabolism | Proteasome Endopeptidase Complex - metabolism | Index Medicus | Virus-Cell Interactions
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10. Full Text Asymmetric Modification of Hepatitis B Virus (HBV) Genomes by an Endogenous Cytidine Deaminase inside HBV Cores Informs a Model of Reverse Transcription
by Nair, Smita and Zlotnick, Adam
Journal of virology, ISSN 0022-538X, 05/2018, Volume 92, Issue 10
Life Sciences & Biomedicine | Science & Technology | Virology | Hepatitis B virus - enzymology | Genome, Viral - genetics | Humans | DNA, Viral - metabolism | Mutation - genetics | DNA, Circular - metabolism | Reverse Transcription - genetics | Hep G2 Cells | Proteins - metabolism | RNA, Viral - genetics | APOBEC-3G Deaminase - metabolism | DNA Packaging - genetics | Cytidine Deaminase - metabolism | Hepatitis B virus - genetics | Cell Line, Tumor | Deamination - genetics | RNA, Viral - metabolism | Capsid - metabolism | DNA, Viral - genetics | Index Medicus
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