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NeuroImage: Clinical, ISSN 2213-1582, 2019, Volume 21, pp. 101621 - 101621
Although single nucleotide polymorphisms of membrane-spanning 4A ( ) (rs670139) and several other susceptibility genes have shown interaction effects on the... 
Calculation | Genetic interaction | APOE | MS4A | Executive control network | COMMON VARIANTS | BRAIN ATROPHY | NEUROIMAGING | APOLIPOPROTEIN-E | IMPAIRMENT | IMPACT | APOE EPSILON-4 STATUS | MEMORY | NEUROINFLAMMATION | CONNECTIVITY | VERSION
Journal Article
FASEB Journal, ISSN 0892-6638, 07/2018, Volume 32, Issue 7, pp. 3536 - 3546
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 02/2019, Volume 15, Issue 2, pp. 258 - 266
Journal Article
JAMA NEUROLOGY, ISSN 2168-6149, 10/2017, Volume 74, Issue 10, pp. 1167 - 1168
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 11/2012, Volume 84, Issue 3, pp. 793 - 799
In humans, apolipoprotein E (apoE) is encoded by three major alleles (ε2, ε3, and ε4) and, compared to apoE3, apoE4 increases the risk of developing Alzheimer... 
Irradiation | ApoE | ROS
Journal Article
Neurobiology of aging, ISSN 0197-4580, 04/2019
The ε4 allele of APOE is a well-established genetic risk factor for cognitive aging and dementia, but its influence on early life cognition is unknown.... 
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 09/2018, Volume 19, Issue 9, p. 2621
Angiotensin (Ang) II triggers vulnerable atherosclerotic plaque development. Bone marrow (BM)-derived cells are key players in atherogenesis but whether Ang II... 
Vulnerable plaque | 2-kidney | Atherosclerosis | Bone marrow transplantation | 1-clip apoe−/− mice | Inflammation | Angiotensin ii | atherosclerosis | REGRESSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, MULTIDISCIPLINARY | bone marrow transplantation | 1-clip ApoE(-/-) mice | PATHOGENESIS | TELMISARTAN | vulnerable plaque | inflammation | RENIN INHIBITION | CARDIOVASCULAR-DISEASE | APOE(-/-) MICE | Angiotensin II | E-DEFICIENT MICE | MACROPHAGE POLARIZATION | PROGRESSION | Plaque, Atherosclerotic - genetics | Bone Marrow Cells - cytology | Humans | Liver - metabolism | Lipid Metabolism | Plaque, Atherosclerotic - immunology | Angiotensins - adverse effects | Plaque, Atherosclerotic - chemically induced | Gene Knockdown Techniques | Gene Expression Regulation - drug effects | Receptor, Angiotensin, Type 1 - genetics | Animals | Liver - drug effects | Apolipoproteins E - genetics | Bone Marrow Transplantation | Bone Marrow Cells - drug effects | Mice | Cytokines - genetics | Disease Models, Animal | Atherogenesis | Genes | Liver | Helper cells | Smooth muscle | Activation | Lymphocytes T | Macrophages | Apolipoprotein E | Lymphocytes | Bone marrow | Aorta | Lipid metabolism | Lesions | Plaques | Spleen | Phenotypes | Stability | Kidneys | Cytokines | Markers | Muscles | Interleukin 12 | Tumor necrosis factor-α | Metabolism | Gene expression | Cholesterol | Monocytes | Arteriosclerosis | Collagen | Angiotensin | Laboratories | Lipids | Cardiovascular disease | Genotype & phenotype | Sinuses | Rodents | Apolipoproteins | IL-1β | Stem cells | Low density lipoprotein receptors | Index Medicus | 2-kidney, 1-clip ApoE−/− mice
Journal Article
Cytokine, ISSN 1043-4666, 03/2017, p. 154089
This review summarizes the current data on the interleukin (IL)-17A pathway in experimental atherosclerosis and clinical data.IL-17A is a prominent cytokine... 
Apoe | Interleukin-17 | Vascular inflammation | mice | Atherosclerosis | Macrophage
Journal Article
04/2008
Background : The present investigation is aimed at examining the Apolipoprotein E (APOE) genotypic influence on coronary heart disease (CHD) risk in northwest... 
APOE polymorphism | Apolipoprotein E | coronary heart disease | Punjab | APOE
Web Resource
Journal of the American Geriatrics Society, ISSN 0002-8614, 04/2019, Volume 67, Issue 4, pp. 734 - 740
OBJECTIVES To examine the effects of age and race on the association of apolipoprotein E (APOE) genotypes with cognitive decline in a population sample. DESIGN... 
minority aging | cognitive decline | APOE genotypes | E EPSILON-2 ALLELE | APOE GENOTYPE | ALZHEIMERS-DISEASE | RACIAL-DIFFERENCES | RISK | AMERICANS | GERIATRICS & GERONTOLOGY | COMMUNITY | MEMORY | APOE-EPSILON-4 | GERONTOLOGY | ASSOCIATION | African Americans | Genotype | Genetic aspects | Apolipoproteins | Statistics | Memory
Journal Article
British Journal of Nutrition, ISSN 0007-1145, 11/2013, Volume 110, Issue 10, pp. 1751 - 1759
Journal Article
Atherosclerosis, ISSN 0021-9150, 01/2018, Volume 268, pp. 207 - 214
We aimed to evaluate a possible atheroprotective effect of saffron aqueous extract (SFE), and its potential anti-inflammatory mechanisms, in apoE knockout ( )... 
Inflammation | Matrix metalloproteinases | Saffron | ApoE−/− mice | Crocetin | Atherosclerosis | ApoE | mice | CARDIAC & CARDIOVASCULAR SYSTEMS | CORONARY | MACROPHAGES | SERUM | ApoE(-/-) mice | DISEASE | CAROTID PLAQUES | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | Diabetes Mellitus, Experimental - drug therapy | Plant Extracts - pharmacology | Atherosclerosis - genetics | Aortic Diseases - blood | Male | Aorta - metabolism | Diabetes Mellitus, Experimental - blood | Dose-Response Relationship, Drug | Diet, High-Fat | Inflammation Mediators - metabolism | Aortic Diseases - prevention & control | Anti-Inflammatory Agents - pharmacokinetics | Anti-Inflammatory Agents - isolation & purification | Plant Lectins - chemistry | Aortic Diseases - pathology | Atherosclerosis - pathology | Hypoglycemic Agents - pharmacokinetics | Anti-Inflammatory Agents - pharmacology | Aorta - drug effects | Mice, Inbred C57BL | Plant Extracts - isolation & purification | Biomarkers - blood | Mice, Knockout, ApoE | Plaque, Atherosclerotic | Mannose-Binding Lectins - chemistry | Hypoglycemic Agents - pharmacology | Aorta - pathology | Atherosclerosis - blood | Blood Glucose - drug effects | Hypoglycemic Agents - isolation & purification | Aortic Diseases - genetics | Animals | Diabetes Mellitus, Experimental - etiology | Plant Extracts - pharmacokinetics | Triglycerides - blood | Matrix Metalloproteinases - metabolism | Blood Glucose - metabolism | Atherosclerosis - prevention & control | Rupture, Spontaneous | Medical examination | Collagen | Analysis | Development and progression | Triglycerides | Glucose | Apolipoproteins | Gene expression | Macrophages | Dextrose | Blood | Index Medicus
Journal Article
Journal Article
by Shu, H and Shi, YM and Chen, G and Wang, Z and Liu, D and Yue, CX and Ward, BD and Li, WJ and Xu, Z and Chen, GY and Guo, QH and Xu, J and Li, SJ and Zhang, ZJ
CEREBRAL CORTEX, ISSN 1047-3211, 04/2016, Volume 26, Issue 4, pp. 1421 - 1429
The apolipoprotein E (APOE) I mu 4 allele is a confirmed genetic risk factor and the APOE I mu 2 allele is a protective factor related to late-onset... 
imaging genetics | APOE GENOTYPE | PATTERNS | DEFAULT-MODE NETWORK | MECHANISMS | NEUROSCIENCES | COGNITIVE DECLINE | functional connectivity | APOE-EPSILON-4 | apolipoprotein E | aging | BRAIN ACTIVATION | DYSFUNCTION | resting-state fMRI | WORKING-MEMORY
Journal Article