X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (4342) 4342
Publication (551) 551
Book Review (417) 417
Book Chapter (24) 24
Conference Proceeding (20) 20
Dissertation (11) 11
Magazine Article (2) 2
Data Set (1) 1
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (3022) 3022
humans (2654) 2654
apoe (2074) 2074
male (1956) 1956
female (1919) 1919
alzheimer's disease (1531) 1531
aged (1522) 1522
apolipoproteins e - genetics (1444) 1444
neurosciences (1443) 1443
genotype (1323) 1323
middle aged (1196) 1196
apolipoproteins (1167) 1167
alzheimers-disease (1096) 1096
apoe genotype (1046) 1046
apolipoprotein e (951) 951
dementia (947) 947
risk factors (928) 928
clinical neurology (869) 869
alzheimer disease - genetics (857) 857
aged, 80 and over (856) 856
risk (731) 731
association (641) 641
adult (629) 629
alleles (602) 602
apolipoprotein e4 - genetics (580) 580
geriatrics & gerontology (570) 570
genetic aspects (569) 569
apolipoprotein-e (559) 559
animals (555) 555
neurology (505) 505
brain (475) 475
mild cognitive impairment (464) 464
psychiatry (462) 462
genetic predisposition to disease (437) 437
article (432) 432
mice (409) 409
age (402) 402
analysis (389) 389
polymorphism, genetic (382) 382
polymorphism (376) 376
genetics (374) 374
cholesterol (366) 366
aging (365) 365
apolipoprotein-e genotype (361) 361
gene frequency (361) 361
research (351) 351
neuropsychological tests (345) 345
allele (340) 340
lipids (330) 330
atherosclerosis (325) 325
cognition (318) 318
e genotype (311) 311
apolipoprotein e4 (310) 310
biochemistry & molecular biology (308) 308
population (307) 307
genetics & heredity (301) 301
memory (299) 299
case-control studies (286) 286
alzheimer’s disease (283) 283
alzheimers disease (281) 281
internal medicine (252) 252
apolipoproteins e - metabolism (246) 246
disease (246) 246
e polymorphism (246) 246
magnetic resonance imaging (244) 244
gene (243) 243
alzheimer disease - pathology (240) 240
cohort studies (231) 231
genes (224) 224
alzheimer disease (217) 217
physiological aspects (213) 213
cognitive decline (211) 211
genetic research (208) 208
pathology (204) 204
alzheimer disease - metabolism (200) 200
phenotype (200) 200
genome-wide association (199) 199
polymorphism, single nucleotide (198) 198
brain - pathology (197) 197
cell biology (193) 193
mice, inbred c57bl (191) 191
diagnosis (190) 190
health aspects (184) 184
neurodegenerative diseases (183) 183
onset (183) 183
medical research (177) 177
proteins (177) 177
abridged index medicus (174) 174
cognition disorders - genetics (174) 174
biomarkers (173) 173
risk-factors (173) 173
apolipoprotein-e polymorphism (171) 171
expression (171) 171
genetic predisposition to disease - genetics (170) 170
alzheimer disease - epidemiology (169) 169
studies (169) 169
adolescent (166) 166
age of onset (166) 166
longitudinal studies (166) 166
disease progression (163) 163
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (4330) 4330
Spanish (23) 23
French (8) 8
German (5) 5
Korean (4) 4
Portuguese (4) 4
Russian (3) 3
Chinese (2) 2
Czech (2) 2
Japanese (2) 2
Polish (2) 2
Italian (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2014, Volume 289, Issue 44, pp. 30538 - 30555
Previous data demonstrate that bexarotene (Bex), retinoid X receptor (RXR) agonist, reduces soluble and insoluble amyloid-beta (A beta) in Alzheimer disease... 
BEXAROTENE THERAPY | ABCA1 | ALZHEIMERS-DISEASE | DEPOSITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIVER | A-BETA | TRANSGENIC MOUSE MODEL | MILD COGNITIVE IMPAIRMENT | BRAIN | APOLIPOPROTEIN-E | Disks Large Homolog 4 Protein | Liver - pathology | Nicotinic Acids - pharmacokinetics | Humans | Male | Tetrahydronaphthalenes - adverse effects | ATP Binding Cassette Transporter 1 - metabolism | Liver - drug effects | Tetrahydronaphthalenes - administration & dosage | Amyloid beta-Peptides - metabolism | Lipoproteins - metabolism | ATP-Binding Cassette Transporters - metabolism | Membrane Proteins - metabolism | Nicotinic Acids - administration & dosage | Drug Evaluation, Preclinical | Nicotinic Acids - adverse effects | Retinoid X Receptors - metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 1 | Bexarotene | Peptide Fragments - metabolism | Administration, Oral | Mice, Inbred C57BL | Solubility | Alzheimer Disease - drug therapy | Tetrahydronaphthalenes - pharmacokinetics | Genotype | Mice, Transgenic | Organ Size - drug effects | Animals | Retinoid X Receptors - agonists | Apolipoproteins E - genetics | Guanylate Kinases - metabolism | Index Medicus | Molecular Bases of Disease | Oligomeric Aβ | Alzheimer Disease | Drug Delivery | Aβ Complex | Apolipoprotein E (ApoE) | Amyloid-β (AB) | RXR Agonists | Hepatomegaly | ABCG1 Lipid Transporters | Drug Action | ApoE
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2016, Volume 51, pp. 104 - 112
Abstract Blood-brain barrier (BBB) dysfunction might be an important component of many neurodegenerative disorders. In this study, we investigated its role in... 
Neurology | Internal Medicine | APOE ε4 | Amyloid | Diabetes | Blood-brain barrier | Vascular pathology | Dementia | ALZHEIMERS-DISEASE | COGNITIVE IMPAIRMENT | APOE epsilon 4 | FRONTOTEMPORAL LOBAR DEGENERATION | CEREBROSPINAL-FLUID | DEPENDENT MANNER | NEUROSCIENCES | GERIATRICS & GERONTOLOGY | TIGHT JUNCTIONS | VASCULAR DEMENTIA | DYSFUNCTION | DIAGNOSTIC-CRITERIA | LEWY BODIES | Diabetes Mellitus - blood | Capillary Permeability | Humans | Middle Aged | Blood-Brain Barrier - physiopathology | Immunoglobulins - cerebrospinal fluid | Vascular Endothelial Growth Factor A - cerebrospinal fluid | Cell Adhesion Molecules - cerebrospinal fluid | Genotype | Male | Diabetes Mellitus - cerebrospinal fluid | Dementia - etiology | Serum Albumin | Cell Adhesion Molecule-1 | Apolipoproteins E - genetics | Amyloid beta-Peptides - metabolism | Aged, 80 and over | Albumins - cerebrospinal fluid | Diabetes Mellitus - etiology | Female | Aged | Cohort Studies | Nervous system diseases | Neurosciences | PET imaging | Endothelial growth factors | Physiological aspects | Brain damage | Genetic aspects | Permeability | Apolipoproteins | Alzheimer's disease | Endothelium | Medical research | Medicine, Experimental | Index Medicus | lewy bodies | vascular dementia | Geriatrics & Gerontology | Neurosciences & Neurology | dependent manner | dysfunction | cerebrospinal-fluid | Endokrinologi och diabetes | diagnostic-criteria | cognitive impairment | tight junctions | Geriatrik | frontotemporal lobar degeneration | Neurovetenskaper | Endocrinology and Diabetes | Geriatrics | alzheimers-disease
Journal Article
Journal of the American Geriatrics Society, ISSN 0002-8614, 12/2016, Volume 64, Issue 12, pp. 2479 - 2486
To investigate the timing (mid- vs late life) of physical activity, apolipoprotein (APO)E ε4, and risk of incident mild cognitive impairment (MCI). Prospective... 
mild cognitive impairment | APOE | physical activity | APOE e4 | Apolipoprotein E4 - genetics | Prospective Studies | Humans | Genotype | Male | Risk | Motor Activity | Cognitive Dysfunction - prevention & control | Incidence | Aged, 80 and over | Cognitive Dysfunction - genetics | Female | Surveys and Questionnaires | Aged | Index Medicus | Mild Cognitive Impairment | Physical Activity
Journal Article
Journal Article
Journal Article