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Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2014, Volume 289, Issue 44, pp. 30538 - 30555
Previous data demonstrate that bexarotene (Bex), retinoid X receptor (RXR) agonist, reduces soluble and insoluble amyloid-beta (A beta) in Alzheimer disease... 
BEXAROTENE THERAPY | ABCA1 | ALZHEIMERS-DISEASE | DEPOSITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIVER | A-BETA | TRANSGENIC MOUSE MODEL | MILD COGNITIVE IMPAIRMENT | BRAIN | APOLIPOPROTEIN-E | Disks Large Homolog 4 Protein | Liver - pathology | Nicotinic Acids - pharmacokinetics | Humans | Male | Tetrahydronaphthalenes - adverse effects | ATP Binding Cassette Transporter 1 - metabolism | Liver - drug effects | Tetrahydronaphthalenes - administration & dosage | Amyloid beta-Peptides - metabolism | Lipoproteins - metabolism | ATP-Binding Cassette Transporters - metabolism | Membrane Proteins - metabolism | Nicotinic Acids - administration & dosage | Drug Evaluation, Preclinical | Nicotinic Acids - adverse effects | Retinoid X Receptors - metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 1 | Bexarotene | Peptide Fragments - metabolism | Administration, Oral | Mice, Inbred C57BL | Solubility | Alzheimer Disease - drug therapy | Tetrahydronaphthalenes - pharmacokinetics | Genotype | Mice, Transgenic | Organ Size - drug effects | Animals | Retinoid X Receptors - agonists | Apolipoproteins E - genetics | Guanylate Kinases - metabolism | Index Medicus | Molecular Bases of Disease | Oligomeric Aβ | Alzheimer Disease | Drug Delivery | Aβ Complex | Apolipoprotein E (ApoE) | Amyloid-β (AB) | RXR Agonists | Hepatomegaly | ABCG1 Lipid Transporters | Drug Action | ApoE
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2010, Volume 107, Issue 22, pp. 10256 - 10261
Journal Article
Journal Article
Journal Article
Journal Article