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Journal of Neurochemistry, ISSN 0022-3042, 02/2005, Volume 92, Issue 3, pp. 628 - 636
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2015, Volume 10, Issue 9, pp. e0131199 - e0131199
Obesity and type 2 diabetes are risk factors of Alzheimer's disease (AD). We reported that a high fat diet (HFD) promotes amyloid precursor protein (APP)... 
DEMENTIA | ALZHEIMERS-DISEASE | MEMORY DEFICITS | MULTIDISCIPLINARY SCIENCES | MUTATION | SECRETASE PROTEIN | CELL-SURFACE | RISK | GENERATION | ENDOCYTOSIS | TRANSGENIC MICE | Amyloid Precursor Protein Secretases - genetics | Cricetulus | Humans | Protein Transport - drug effects | Aspartic Acid Endopeptidases - genetics | Mutation, Missense | Obesity - genetics | Alzheimer Disease - pathology | Proteolysis - drug effects | Adaptor Protein Complex 2 - metabolism | Dietary Fats - pharmacology | Amyloid beta-Protein Precursor - metabolism | CHO Cells | Cricetinae | Dietary Fats - adverse effects | Mice, Transgenic | Adaptor Protein Complex 2 - genetics | Protein Transport - genetics | Obesity - metabolism | Obesity - pathology | Amyloid Precursor Protein Secretases - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Aspartic Acid Endopeptidases - metabolism | Alzheimer Disease - metabolism | Mice | Alzheimer Disease - genetics | Amino Acid Substitution | Health sciences | Clathrin | Complex formation | Trafficking | Cell surface | Risk factors | High fat diet | Proteins | Precursors | Transgenic animals | Rodents | Cleavage | Diabetes mellitus (non-insulin dependent) | Alzheimer's disease | University graduates | Obesity | Medical research | Enzymes | b-Site APP cleaving enzyme 1 | Diabetes mellitus | Transgenic mice | Health risks | Risk analysis | Amyloid precursor protein | Medicine | Neurology | Brain research | Diet | Internalization | Mutation | Alzheimers disease | High protein diet | Dementia | Index Medicus
Journal Article
Journal Article
FEBS Journal, ISSN 1742-464X, 01/2015, Volume 282, Issue 1, pp. 65 - 73
Journal Article
Experimental and Molecular Medicine, ISSN 1226-3613, 02/2019, Volume 51, Issue 2, pp. 12 - 18
Journal Article
Clinical and Translational Science, ISSN 1752-8054, 09/2019, Volume 12, Issue 5, pp. 545 - 555
β‐site amyloid precursor protein‐cleaving enzyme 1 ( BACE 1) is required for the production of β‐amyloid peptides, which are implicated in the etiology of... 
Elderly people | Peptides | Males | Proteins | Metabolites | Etiology | Precursors | Safety | Alzheimer's disease | Drug dosages | Enzymes | b-Site APP cleaving enzyme 1 | Young adults | Stock options | Neurodegenerative diseases | Pharmacology | Metabolism | Amyloid precursor protein | Studies | Inhibitors | Mutation | Alzheimers disease | Pharmacokinetics | Females | Geriatrics
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 04/2016, Volume 59, Issue 7, pp. 3231 - 3248
Journal Article
EUROPEAN JOURNAL OF NEUROSCIENCE, ISSN 0953-816X, 06/2013, Volume 37, Issue 12, pp. 1962 - 1969
Cleavage of amyloid- precursor protein (APP) at the Asp1 -secretase site of the amyloid- protein (A) domain by -site A precursor protein-cleaving enzyme 1... 
BETA-SECRETASE | APP | secretase | CDNA | NEUROSCIENCES | MISSENSE MUTATIONS | MOUSE MODELS | BACE1 | A beta | CLONING | BACE1 GENE-EXPRESSION | DOWN-SYNDROME | DISEASE | PURIFICATION | TRANSCRIPTIONAL REGULATION | Enzymes | Genetic engineering | Alzheimer's disease | Analysis | Amyloid beta-protein
Journal Article