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phosphatidylinositol 4,5-bisphosphate (24) 24
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Journal of Cell Science, ISSN 0021-9533, 06/2018, Volume 131, Issue 11
Journal Article
Traffic, ISSN 1398-9219, 01/2004, Volume 5, Issue 1, pp. 20 - 36
In comparison to the internalization pathways of endocytosis, the recycling pathways are less understood. Even less defined is the process of regulated... 
cell motility | endocytic recycling | Rab11 | integrin | ARF6 | Cell motility | Integrin | Endocytic recycling
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 6/2003, Volume 161, Issue 6, pp. 1143 - 1150
Journal Article
Journal of Cerebral Blood Flow and Metabolism, ISSN 0271-678X, 2018, Volume 39, Issue 10, pp. 271678X18777916 - 2060
Blood-brain barrier (BBB) disruption in neurological disorders remains an intractable problem with limited therapeutic options. Here, we investigate whether... 
Robo4-paxillin-ARF6 signaling | trans-endothelial permeability | annexin A2 | Human brain microvascular endothelial cells | junctional proteins
Journal Article
CURRENT BIOLOGY, ISSN 0960-9822, 09/2006, Volume 16, Issue 17, pp. 1719 - 1725
Cytokinesis is the final step of cell division and leads to the physical separation of the daughter cells. After the ingression of a cleavage membrane furrow... 
CYTOSKELETAL | EXOCYST | MIDBODY | BIOCHEMISTRY & MOLECULAR BIOLOGY | MAMMALIAN SEPTIN | COMPLETION | CLEAVAGE FURROW | SPERMATOCYTES | PROTEINS | BINDING | ARF6 | CELL BIOLOGY
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 12/2003, Volume 163, Issue 5, pp. 1111 - 1121
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 08/2015, Volume 6
Anti-angiogenic drugs targeting vascular endothelial cell growth factor receptor have provided modest clinical benefit, in part, owing to the actions of... 
DOWNSTREAM EFFECTOR | ACTIVATION | INVASION | METASTASIS | SIGNALING PATHWAY | VEGF | MULTIDISCIPLINARY SCIENCES | INTEGRIN BETA-1 | MET | SMALL GTPASE ARF6 | EXOCYST COMPLEX
Journal Article
Nature, ISSN 0028-0836, 09/2004, Volume 431, Issue 7007, pp. 415 - 422
Phosphatidylinositol-4,5-bisphosphate (PtdIns(4,5) P-2) has an important function in cell regulation both as a precursor of second messenger molecules and by... 
TRANSMITTER RELEASE | TRANSMISSION | DOMAIN | MULTIDISCIPLINARY SCIENCES | POOL | I-GAMMA | ENDOCYTOSIS | PLASMA-MEMBRANE | CLATHRIN | HIPPOCAMPAL SYNAPSES | ARF6
Journal Article
AUTOPHAGY, ISSN 1554-8627, 05/2012, Volume 8, Issue 5, pp. 861 - 863
Autophagosomes may derive membrane from diverse sources, including the plasma membrane, Golgi, endoplasmic reticulum and mitochondria. The plasma membrane... 
autophagy | ATG16L1 | plasma membrane | phagophore | SNARE | ARF6 | CELL BIOLOGY
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 31, pp. 12095 - 12104
Epithelial cells form tissues with many functions, including secretion and environmental separation and protection. Glandular epithelial tissues comprise cysts... 
ARF6 ACTIVATION | cell sorting | RECEPTOR | epithelial cell | CDC42 | glandular epithelium | ENDOSOMES | endosome | morphogenesis | receptor internalization | endocytosis | cell polarity | BREAST-CANCER INVASION | membrane trafficking | extracellular signal regulated kinase | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | cadherin | ADHESION | cell biology | SIGNALING PATHWAY | epithelial cyst | RAB35 | cMet receptor | PROTEINS | GTPase | mitotic spindle | ARF6 | Cadherins - metabolism | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Extracellular Signal-Regulated MAP Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Endosomes - metabolism | Cysts - metabolism | Endocytosis | Spindle Apparatus - metabolism | Cell Division | Organoids - metabolism | Endosomes - drug effects | Endosomes - ultrastructure | Madin Darby Canine Kidney Cells | Organoids - ultrastructure | Cell Membrane - metabolism | Cell Polarity - drug effects | Flavonoids - pharmacology | ADP-Ribosylation Factors - metabolism | Cadherins - genetics | Spindle Apparatus - ultrastructure | ADP-Ribosylation Factors - genetics | Cell Membrane - drug effects | Morphogenesis - genetics | Signal Transduction | Tissue Culture Techniques | Gene Expression Regulation | Cell Membrane - ultrastructure | Cysts - ultrastructure | Cell Adhesion - drug effects | Animals | Dogs | Organoids - drug effects | Protein Kinase Inhibitors - pharmacology | Spindle Apparatus - drug effects | Cell Biology
Journal Article
JOURNAL OF CELL BIOLOGY, ISSN 0021-9525, 06/2012, Volume 197, Issue 7, pp. 983 - 996
Epidermal growth factor receptor (EGFR) signaling is one of the crucial factors in breast cancer malignancy. Breast cancer cells often overexpress Arf6 and its... 
FIBRONECTIN RECEPTOR | 3D MICROENVIRONMENTS | PROTEIN-KINASE-D | CELL-MIGRATION | TRANS-GOLGI NETWORK | EXTRACELLULAR-MATRIX DEGRADATION | INTEGRIN BETA-1 | PLASMA-MEMBRANE | ALPHA-5-BETA-1 INTEGRIN | ARF6 | CELL BIOLOGY
Journal Article
DEVELOPMENTAL CELL, ISSN 1534-5807, 11/2005, Volume 9, Issue 5, pp. 663 - 673
Components of intracellular signaling that mediate the stimulation-dependent recycling of integrins are being identified, but key transport effectors that are... 
VESICLES | PATHWAY | KINASE | GROWTH | ALPHA-5-BETA-1 | DEVELOPMENTAL BIOLOGY | PROMOTES | ARF6 | CELL BIOLOGY
Journal Article
Molecular and cellular biology, ISSN 0270-7306, 02/2019, Volume 39, Issue 3
Tumor cell invasion is one result of the bidirectional interactions occurring between tumor cells and the surrounding milieu. The ability of tumor cells to... 
fascin | cell invasion | microvesicles | INVADOPODIA | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHENOTYPE | CANCER | CELL BIOLOGY | MODES | EXTRACELLULAR VESICLES | RAB35 | PROTEINS | ARF6 | PLASTICITY
Journal Article
Philosophical Transactions of the Royal Society B: Biological Sciences, ISSN 0962-8436, 02/2019, Volume 374, Issue 1765, p. 20180148
Macropinocytosis is a form of endocytosis that brings large fluid-filled endosomes into the cell interior. Macrophages and dendritic cells are especially... 
endocytosis | macropinocytosis | cargo sorting | RAS | Arf6 | clathrin-independent endocytosis | ADP-RIBOSYLATION FACTOR | ROUTE | DOWNSTREAM EFFECTOR | PHOSPHOLIPASE-D | TRAFFICKING | MECHANISMS | CARGO | ROLES | BIOLOGY | PROTEINS
Journal Article
Development (Cambridge), ISSN 0950-1991, 02/2019, Volume 146, Issue 3, p. dev172106
A switch in the response of commissural axons to the repellent Slit is crucial for ensuring that they cross the ventral midline only once. However, the... 
Slit-Robo | Commissural neurons | Axon guidance | Endocytic recycling | Midline | Arf6 | MIDLINE SWITCH | RESPONSIVENESS | SONIC HEDGEHOG | RECEPTOR | DEVELOPMENTAL BIOLOGY | GUIDANCE | ROBO | ENDOCYTOSIS | GROWTH | PROTEINS | MEMBRANE-TRANSPORT
Journal Article
JOURNAL OF CELL SCIENCE, ISSN 0021-9533, 05/2012, Volume 125, Issue 9, pp. 2235 - 2243
Two small GTPases, Rab and Arf, are well-known molecular switches that function in diverse membrane-trafficking routes in a coordinated manner; however, very... 
DOMAIN | PHAGOCYTOSIS | Rab35 | TRAFFICKING | Centaurin-beta 2 | CELL-SHAPE | PLASMA-MEMBRANE | CELL BIOLOGY | Membrane traffic | ACAP2 | CYTOKINESIS | SLP4-A/GRANUPHILIN-A | CORE VESICLE EXOCYTOSIS | GTPASE-ACTIVATING PROTEINS | BINDING | Arf6 | Neurite outgrowth
Journal Article
Small GTPases, ISSN 2154-1248, 01/2018, pp. 1 - 7
Precise trafficking events, such as those that underlie synaptic transmission and plasticity, require complex regulation. G-protein signaling plays an... 
AMPAR trafficking | GTPase signaling | LTD | Arf6 | BRAG1/IQSEC2
Journal Article
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