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Thrombosis Research, ISSN 0049-3848, 12/2017, Volume 160, pp. 51 - 57
Extracellular histones are reported to increase thrombin generation in the plasma and induce endothelial cell death . These effects of histones were suggested... 
Histones | Protein C | Thrombin | Thrombomodulin | Cell death | SEPSIS | MODEL | HUMAN SOLUBLE THROMBOMODULIN | INACTIVATION | MAJOR MEDIATORS | DISSEMINATED INTRAVASCULAR COAGULATION | FACTOR-V | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | ART-123
Journal Article
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, ISSN 0098-7484, 05/2019, Volume 321, Issue 20, pp. 1978 - 1980
Journal Article
Journal of Clinical Medicine, ISSN 2077-0383, 09/2019, Volume 8, Issue 10, p. 1553
Disseminated intravascular coagulation (DIC) is a catastrophic systemic disorder of coagulation, resulting in uncontrollable bleeding, multiple organ failure,... 
systemic inflammatory response syndrome | recombinant thrombomodulin | disseminated intravascular coagulation | sepsis | ART-123
Journal Article
Liver Transplantation, ISSN 1527-6465, 02/2019, Volume 25, Issue 2, pp. 252 - 259
Recombinant human soluble thrombomodulin (ART‐123) is an anticoagulant and anti‐inflammatory agent clinically used for treatment of disseminated intravascular... 
SURGERY | GROUP BOX-1 PROTEIN | TRANSPLANTATION | ISCHEMIA-REPERFUSION INJURY | FIBRINOLYSIS | THROMBIN GENERATION | CIRRHOSIS | DOUBLE-BLIND | COAGULATION | INHIBITOR | GASTROENTEROLOGY & HEPATOLOGY | HEMOSTASIS | ART-123 | Original
Journal Article
by Lin, SM and Wang, YM and Lin, HC and Lee, KY and Huang, CD and Liu, CY and Wang, CH and Kuo, HP
CRITICAL CARE MEDICINE, ISSN 0090-3493, 03/2008, Volume 36, Issue 3, pp. 683 - 689
Objective. To determine serum concentrations of thrombomodulin, the marker of endothelial injury, in patients with sepsis-induced disseminated intravascular... 
ENDOTHELIAL-CELL INJURY | multiorgan dysfunction syndrome | endothelial injury | ORGAN FAILURE | PROTEIN-C | SOLUBLE HUMAN THROMBOMODULIN | PLASMA | NECROSIS | HEALTHY MALE-VOLUNTEERS | PATHWAY | thrombomodulin | IN-VIVO | mortality | disseminated intravascular coagulation | sepsis | ART-123 | CRITICAL CARE MEDICINE
Journal Article
Expert Opinion on Pharmacotherapy, ISSN 1465-6566, 12/2018, Volume 19, Issue 18, pp. 1999 - 2009
Journal Article
Journal Article
Gut and Liver, ISSN 1976-2283, 07/2018, Volume 12, Issue 4, pp. 471 - 477
Background/Aims: Recently, recombinant human soluble thrombomodulin (rTM) has been developed as a new drug for disseminated intravascular coagulation (DIC).... 
Disseminated intravascular coagulation | Thrombosis | Acute cholangitis | Recombinant soluble thrombomodulin | MORTALITY | RISK-FACTORS | MANAGEMENT | EFFICACY | SAFETY | TECHNICAL TIPS | DOUBLE-BLIND | ACUTE-PANCREATITIS | GASTROENTEROLOGY & HEPATOLOGY | SEVERE SEPSIS | ART-123 | Original
Journal Article
Clinical and Applied Thrombosis/Hemostasis, ISSN 1076-0296, 9/2018, Volume 24, Issue 6, pp. 859 - 866
Journal Article