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Toxicology and Applied Pharmacology, ISSN 0041-008X, 09/2019, Volume 379, p. 114687
Arsenic-induced side effects limit its application in the treatment of acute promyelocytic leukemia (APL). We recently demonstrated that AS3MT 14215... 
AS3MT polymorphism | Arsenic trioxide | Arsenic metabolism | Acute promyelocytic leukemia | Liver injury | POPULATION | METHYLTRANSFERASE AS3MT | RISK | MECHANISMS | SKIN-LESIONS | PHARMACOLOGY & PHARMACY | TOXICOLOGY | EXPOSURE
Journal Article
Toxicological Sciences, ISSN 1096-6080, 11/2018, Volume 166, Issue 1, pp. 219 - 227
Abstract Although arsenic has shown remarkable therapeutic efficacy in patients with acute promyelocytic leukemia (APL), its side effects are rarely reported.... 
Arsenic trioxide | Arsenic metabolism | Acute promyelocytic leukemia | AS3MT polymorphisms | Hematological and biochemical values | METHYLTRANSFERASE AS3MT | METHYLATION | arsenic trioxide | hematological and biochemical values | GSTO | RISK | arsenic metabolism | CHILDREN | acute promyelocytic leukemia | GENES | TOXICOLOGY | DRINKING-WATER | ASSOCIATION
Journal Article
Journal Article
by Guan, FL and Zhang, TX and Li, L and Fu, DK and Lin, HL and Chen, G and Chen, T
SCHIZOPHRENIA RESEARCH, ISSN 0920-9964, 10/2016, Volume 176, Issue 2-3, pp. 125 - 130
Schizophrenia is a devastating psychiatric condition with high heritability. Replicating the specific genetic variants that increase susceptibility to... 
METAANALYSIS | VARIANTS | PSYCHIATRY | Schizophrenia | DTNBP1 | RISK | POLYMORPHISM | Common variants | NT5C2 | TRANSCRIPTION FACTOR PAX5 | AS3MT | SUSCEPTIBILITY LOCUS | CNNM2 | LINKAGE
Journal Article
International Journal of Hematology-Oncology and Stem Cell Research, ISSN 1735-1243, 2017, Volume 11, Issue 1, pp. 19 - 23
Journal Article
日本衛生学雑誌, ISSN 0021-5082, 2015, Volume 70, Issue 3, pp. 186 - 196
「1. 背景」無機ヒ素(inorganic arsenic;IA)は, 発がん物質としてよく知られている. 1980年代以降, 天然由来のIAによる地下水の汚染が世界各地, とくにバングラデシュやインドといった途上国で顕在化している. これらのヒ素汚染地域では, 地下水から世界保健機構(World Health... 
Journal Article
Archives of Toxicology, ISSN 0340-5761, 07/2017, Volume 91, Issue 7, pp. 2617 - 2627
Susceptibility to toxic effects of inorganic arsenic (iAs) depends, in part, on efficiency of iAs methylation by arsenic (+3 oxidation state) methyltransferase... 
Obesity | Insulin resistance | As3mt-knockout mice | Metabolic phenotype | Arsenic | URINARY-BLADDER EPITHELIUM | METHYLATED ARSENICALS | GLUCOSE-HOMEOSTASIS | STIMULATED INSULIN-SECRETION | SOUTHWESTERN TAIWAN | PANCREATIC BETA-CELLS | TRIVALENT ARSENICALS | TOXICOLOGY | SPECIATION ANALYSIS | DRINKING-WATER | ATOMIC ABSORPTION SPECTROMETRY | Liver - metabolism | Methyltransferases - metabolism | Mice, Inbred C57BL | Methyltransferases - genetics | Body Weight - drug effects | Male | Arsenic - toxicity | Body Weight - genetics | Obesity - genetics | Mice, Knockout | Obesity - metabolism | Animals | Arsenic - urine | Arsenic - pharmacokinetics | Liver - drug effects | Body Composition - drug effects | Body Composition - genetics | Insulin Resistance - genetics | Glucose - metabolism | Female | Glucose metabolism | Medical colleges | Blood sugar | Analysis | Transferases | Physiological aspects | Oxidation-reduction reaction | Genetic aspects | Methylation | Insulin | Drinking water | Body fat | Toxicity | Methyltransferase | Sex | Glucose | Composition effects | Body composition | Genotype & phenotype | Body composition (biology) | Rodents | Oxidation | Deionization | Fasting | Exposure | Metabolism | Glucose tolerance | Side effects | Valence | Body mass | Mice | Index Medicus | arsenic | insulin resistance | As3mt knockout mice | obesity | metabolic phenotype
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 10/2012, Volume 264, Issue 1, pp. 121 - 130
Journal Article
ENVIRONMENTAL SCIENCE & TECHNOLOGY, ISSN 0013-936X, 10/2017, Volume 51, Issue 19, pp. 11115 - 11125
Organoarsenicals such as the methylarsenical methylarsenate (MAs(V)) and aromatic arsenicals including roxarsone (4-hydroxy-3-nitro-benzenearsenate or Rox(V))... 
ENVIRONMENTAL SCIENCES | SUBSTRATE-BINDING | PROTOCATECHUATE 3,4-DIOXYGENASE | ENGINEERING, ENVIRONMENTAL | POULTRY LITTER | S-ADENOSYLMETHIONINE METHYLTRANSFERASE | MARKET BASKET SAMPLE | TOXICITY | AS3MT ARSENIC METHYLATION | GROWTH PROMOTERS | ROXARSONE | EXPOSURE
Journal Article
Journal Article
International journal of hematology-oncology and stem cell research, ISSN 2008-3009, 01/2017, Volume 11, Issue 1, pp. 19 - 23
To determine the frequency of the single nucleotide polymorphism M287T in exon 9 of the AS3MT gene in Iranian population and to assess the difference in allele... 
Arsenic | Original | AS3MT gene | Polymorphism
Journal Article