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ast-120 (125) 125
indoxyl sulfate (92) 92
index medicus (71) 71
humans (67) 67
urology & nephrology (66) 66
chronic kidney disease (53) 53
male (53) 53
animals (50) 50
rats (44) 44
oxidative stress (41) 41
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progression (32) 32
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uremic toxins (26) 26
middle aged (25) 25
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oral adsorbent ast-120 (22) 22
uremic toxin (22) 22
aged (20) 20
indican - metabolism (19) 19
rats, sprague-dawley (19) 19
chronic renal failure (17) 17
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nephrology (17) 17
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hemodialysis (14) 14
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pharmacology & pharmacy (14) 14
uremia - metabolism (14) 14
expression (13) 13
kidney failure, chronic - blood (13) 13
microspheres (13) 13
p-cresyl sulfate (13) 13
indican - blood (12) 12
oxidative stress - drug effects (12) 12
renal dialysis (12) 12
treatment outcome (12) 12
development and progression (11) 11
glomerular sclerosis (11) 11
nf-kappa-b (11) 11
oral sorbent (11) 11
organic anion transporters (11) 11
serum (11) 11
sorbent (11) 11
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failure (10) 10
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renal insufficiency, chronic - metabolism (10) 10
risk factors (10) 10
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transplantation (10) 10
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care and treatment (9) 9
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disease models, animal (9) 9
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osteoblast-specific proteins (9) 9
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toxins (9) 9
uremia - blood (9) 9
uremia - drug therapy (9) 9
analysis (8) 8
cardiac & cardiovascular systems (8) 8
ckd (8) 8
experimental uremic rats (8) 8
gene-expression (8) 8
kidney - physiopathology (8) 8
kidney failure, chronic - complications (8) 8
kidney failure, chronic - physiopathology (8) 8
original paper (8) 8
spherical carbon adsorbent (8) 8
toxicology (8) 8
uremia - complications (8) 8
uremia - physiopathology (8) 8
adsorbent ast-120 (7) 7
chronic disease (7) 7
health aspects (7) 7
hematology (7) 7
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Journal Article
Renal Failure, ISSN 0886-022X, 01/2019, Volume 41, Issue 1, pp. 47 - 56
AST-120 (KREMEZIN®) consists of oral, spherical carbon particles that adsorb uremic toxins and their precursors within the gastrointestinal tract, allowing... 
clinical trial | spherical carbon adsorbent | AST-120 | uremic toxin | CKD | MODERATE | MANAGEMENT | UREMIC TOXINS | CARDIOVASCULAR OUTCOMES | FAILURE | INDOXYL SULFATE | DIETARY-PROTEIN RESTRICTION | UROLOGY & NEPHROLOGY | EPPIC TRIALS | ORAL ADSORBENT AST-120 | PROGRESSION
Journal Article
Toxin Reviews, ISSN 1556-9543, 10/2016, Volume 35, Issue 3-4, pp. 171 - 179
Chronic kidney disease (CKD) is associated with accumulation of uremic toxins, especially indoxyl sulfate (IS). IS has multi-directional, adverse influence on... 
hemodialysis | AST-120 | adsorbent | zeolite | probiotic | Indoxyl sulfate | BLOOD-CONCENTRATIONS | OXIDATIVE STRESS | GUM ACACIA | P-CRESYL SULFATE | CHARCOAL ADSORBENT AST-120 | IN-VITRO | ORAL ADSORBENT | TOXICOLOGY | CHRONIC KIDNEY-DISEASE | CARDIOVASCULAR RISK | CHRONIC-RENAL-FAILURE
Journal Article
Journal Article
Blood Purification, ISSN 0253-5068, 10/2019, Volume 48, Issue 3, pp. 215 - 222
Background/Aims: Accumulation of protein-bound uremic toxins (PBUTs) is associated with mortality due to various systemic disorders in patients with chronic... 
Research Article | KIDNEY-DISEASE | CHARCOAL | MORTALITY | REMOVAL | Protein-bound uremic toxins | Hemodialysis | Activated carbons | AST-120 | UROLOGY & NEPHROLOGY | HEMATOLOGY | Direct hemoperfusion
Journal Article
Kidney Research and Clinical Practice(구 대한신장학회지), ISSN 2211-9132, 2017, Volume 36, Issue 1, p. 68
Background: We investigated the long-term effect of AST-120, which has been proposed as a therapeutic option against renal disease progression, in patients... 
Cardiovascular outcome | Uremic toxin | AST-120 | Advanced renal dysfunction | Renal outcome
Journal Article
Journal of Internal Medicine of Taiwan, ISSN 1016-7390, 12/2016, Volume 27, Issue 6, pp. 317 - 332
Journal Article
Heart and Vessels, ISSN 0910-8327, 10/2016, Volume 31, Issue 10, pp. 1625 - 1632
Journal Article
Nephrology Dialysis Transplantation, ISSN 0931-0509, 04/2018, Volume 33, Issue 4, pp. 586 - 597
Background. Hepcidin secreted by hepatocytes is a key regulator of iron metabolism throughout the body. Hepcidin concentrations are increased in chronic kidney... 
iron | hepcidin | indoxyl sulfate | CKD | anemia | OXIDATIVE STRESS | MESSENGER-RNA EXPRESSION | PROXIMAL TUBULAR CELLS | HORMONE HEPCIDIN | TRANSPLANTATION | P-CRESYL SULFATE | SKELETAL-MUSCLE | ARYL-HYDROCARBON RECEPTOR | RENAL-FAILURE | UROLOGY & NEPHROLOGY | NF-KAPPA-B | ORAL ADSORBENT AST-120
Journal Article
Case Reports in Nephrology and Dialysis, ISSN 2296-9705, 06/2018, Volume 8, Issue 2, pp. 107 - 111
We report herein an adult case of chronic kidney disease (CKD) associated with diabetes. The patient had been treated with insulin injection for diabetes 10... 
Case Report | Chronic kidney disease Diabetic kidney disease AST-120 | Urine | Nephrology | Laxatives | Diabetes | Family medical history | Kidney diseases | Patients | Constipation | Patient compliance | Adsorbents | AST-120 | Chronic kidney disease | Diabetic kidney disease
Journal Article
Circulation Journal, ISSN 1346-9843, 2014, Volume 78, Issue 10, pp. 2477 - 2482
Background: Indoxyl sulfate (IS), a uremic toxin, has cardiovascular as well as uremic toxicity. We evaluated the prognostic value of blood IS level for... 
Cardio-renal syndrome | Chronic kidney disease | Uremic toxin | STATEMENT | CARDIAC & CARDIOVASCULAR SYSTEMS | CARDIOLOGY | AST-120 | DISORDERS | PROLIFERATION | HEART-DISEASE | RENAL-FAILURE | CHRONIC KIDNEY-DISEASE | PROGRESSION
Journal Article