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PLoS ONE, ISSN 1932-6203, 12/2017, Volume 12, Issue 12, p. e0189990
Friedreich’s ataxia (FRDA) is a genetic neurodegenerative disorder caused by transcriptional silencing of the frataxin gene (FXN) due to expansions of GAA... 
Heart | Cerebellum | Spinal cord | Cerebral cortex | Disease | Cardiomyopathy | Gallium arsenide | Biochemistry | Tissues | Proteins | Consortia | Frataxin | Lymphocytes | Fibroblasts | Ataxia | Genetics | Pancreas | Stability | Neurodegenerative diseases | Diabetes mellitus | Cortex | Mammals | Gene expression | Patients | Data interpretation | Gene silencing | Life span | Stem cells | Diabetes
Journal Article
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 05/2013, Volume 20, Issue 4, pp. 486 - 494
Journal Article
Cell Reports, ISSN 2211-1247, 08/2016, Volume 16, Issue 5, pp. 1218 - 1227
Journal Article
Stem Cell Research, ISSN 1873-5061, 10/2019, Volume 40, p. 101529
Friedreich's ataxia is caused by large homozygous, intronic expansions of GAA repeats in the frataxin (FXN) gene, resulting in severe downregulation of its... 
Friedreich's ataxia | Isogenic iPSC | Cardiomyocytes | Genome editing | Lipid metabolism | GAA repeats
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 09/2018, Volume 28, Issue 17, pp. 2850 - 2855
Friedreich's ataxia (FRDA) is an incurable neurodegenerative disorder caused by reduced expression of the mitochondrial protein frataxin (FXN). The genetic... 
Friedreich's ataxia | ss-siRNAs | Antisense oligonucleotides | Frataxin | Gene activation | RNAI | CHEMISTRY, MEDICINAL | FRIEDREICHS-ATAXIA | CHEMISTRY, ORGANIC | Friedreich’s ataxia | gene activation | antisense oligonucleotides | frataxin
Journal Article