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01/2012
Accumulated evidence indicates that the activating transcription factor 4 (atf4) is a developmentally relevant gene. Here, we report on the characterization of... 
Eye | Xenopus | atf4 | Neurogenesis | Apoptosis
Web Resource
Journal of Clinical Biochemistry and Nutrition, ISSN 0912-0009, 01/2019, Volume 64, Issue 1, pp. 1 - 12
Journal Article
ARTHRITIS & RHEUMATOLOGY, ISSN 2326-5191, 05/2014, Volume 66, Issue 5, pp. 1266 - 1271
Objective. Nuclear protein 1 (Nupr1) is a stress-inducible protein that is involved in gene transcription. The present study was undertaken to determine... 
P8 | RHEUMATOLOGY | ONSET | ATF4
Journal Article
Journal of Clinical Biochemistry and Nutrition, ISSN 0912-0009, 2018
Recent investigations have clarified the importance of mitochondria in various age-related degenerative diseases, including late-onset Alzheimer’s disease and... 
GCN2 | Nrf2 | mitochondria | ATF4
Journal Article
Neuroscience Letters, ISSN 0304-3940, 09/2019, Volume 709, p. 134352
This study aims to investigate the function and molecular mechanisms of Tribbles homolog 3 (TRB3) on the MPP /MPTP-induced Parkinson’s disease (PD). In this... 
TRB3 | AKT | MAPK | ATF4/CHOP | Parkinson’s disease
Journal Article
Molecules, ISSN 1420-3049, 09/2013, Volume 18, Issue 9, pp. 10146 - 10161
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 07/2015, Volume 35, Issue 30, pp. 10731 - 10749
Journal Article
CANCER SCIENCE, ISSN 1349-7006, 01/2018, Volume 109, pp. 855 - 855
Conference Proceeding
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2018, Volume 115, Issue 4, pp. 780 - 785
Golgi stress response is emerging as a major stress response pathway although molecular players in the process have not been identified. We show that Golgi... 
Golgi stress response | Huntington’s disease | CSE | Monensin | ATF4 | monensin | Biological Sciences
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 07/2018, Volume 38, Issue 27, pp. 6102 - 6113
Activating Transcription Factor 4 (ATF4) has been postulated as a key regulator of learning and memory. We previously reported that specific hippocampal ATF4... 
GABA | GIRK channels | receptors | Neuronal excitability | ATF4 | Cdc42 | GABAB receptors | neuronal excitability
Journal Article
Molecules (Basel, Switzerland), ISSN 1420-3049, 08/2019, Volume 24, Issue 17, p. 3110
In response to cellular stresses, activating transcriptional factor 4 (ATF4) regulates the expression of both stress-relieving genes and apoptosis-inducing... 
Sophora flavescens | kurarinone | TRB3 | ISR | cancer | PERK | ATF4
Journal Article
Molecular Cell, ISSN 1097-2765, 02/2018, Volume 69, Issue 4, pp. 636 - 647.e7
The integrated stress response (ISR) facilitates cellular adaptation to stress conditions via the common target eIF2α. During ISR, the selective translation of... 
FTO | alternative translation | QTI-seq | m6A | epitranscriptome | reinitiation | ribosome scanning | ATF4 | integrated stress response | start codon selection
Journal Article
Journal Article
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 02/2011, Volume 116, Issue 4, pp. 588 - 605
P>Accumulation of misfolded proteins in the endoplasmic reticulum (ER) is the main event leading to the induction of the ER stress-related unfolded protein... 
unfolded protein response | GRP78/BiP | Parkinson's disease | ATF4/CREB-2 | cytochrome c | α-synuclein | ACTIVATION | ER STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GRP78 | BiP | CREB-2 | ENDOPLASMIC-RETICULUM STRESS | AUTOPHAGY | alpha-synuclein | NEUROSCIENCES | CELL-DEATH | PROTEASOME | CALCIUM | NEURONAL CELLS | MICE | AGGREGATION |