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Journal of Thoracic and Cardiovascular Surgery, The, ISSN 0022-5223, 2017, Volume 154, Issue 3, pp. 978 - 988.e1
Abstract Objective Thrombosis persists as a leading cause of morbidity and mortality. Given that the endothelial cell (EC) plays a central role in regulating... 
Cardiothoracic Surgery | ATG7 | autophagy | thrombosis | RAPAMYCIN | SURGERY | CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | NEURODEGENERATION | MECHANISMS | DRUG-ELUTING STENT | RESPIRATORY SYSTEM | DISEASE | BIOLOGY | STRESS | HEMOSTASIS | TISSUE FACTOR | Health aspects | Thrombosis | Mortality | Blood clot | Endothelium | Analysis
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2012, Volume 287, Issue 42, pp. 35576 - 35588
Tetrandrine, a bisbenzylisoquinoline alkaloid isolated from the broadly used Chinese medicinal herb Stephaniae tetrandrae, exhibits potent antitumor effects... 
CYTOCHROME-C | APOPTOSIS | COLON-CANCER CELLS | ACTIVATION | THERAPY | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIA | GROWTH | DEATH | PERMEABILIZATION | Transcription, Genetic - drug effects | Reactive Oxygen Species - metabolism | Microtubule-Associated Proteins - genetics | Humans | Ubiquitin-Activating Enzymes - biosynthesis | Male | Extracellular Signal-Regulated MAP Kinases - metabolism | Neoplasm Proteins - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Autophagy - drug effects | Benzylisoquinolines - chemistry | Dose-Response Relationship, Drug | Carcinoma, Hepatocellular - drug therapy | MAP Kinase Signaling System - genetics | Mitochondria - genetics | Carcinoma, Hepatocellular - genetics | Liver Neoplasms - pathology | Autophagy - genetics | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Stephania tetrandra - chemistry | Antineoplastic Agents, Phytogenic - pharmacokinetics | Benzylisoquinolines - pharmacology | Gene Expression Regulation, Neoplastic - genetics | Ubiquitin-Activating Enzymes - genetics | Liver Neoplasms - genetics | Liver Neoplasms - drug therapy | Antineoplastic Agents, Phytogenic - chemistry | Mitochondria - metabolism | Mitochondria - pathology | Microtubule-Associated Proteins - biosynthesis | Hep G2 Cells | Xenograft Model Antitumor Assays | Autophagy-Related Protein 7 | Animals | MAP Kinase Signaling System - drug effects | Mice, Nude | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Mice | Mice, Inbred BALB C | Transcription, Genetic - genetics | Carcinoma, Hepatocellular - metabolism | Index Medicus | Gene Regulation | Cancer Therapy | Autophagy-related Gene 7 (ATG7) | Tetrandrine | Reactive Oxygen Species (ROS) | Signal Transduction | Autophagy | Anticancer Drug | ERK | Hepatocellular Carcinoma
Journal Article
Frontiers in Physiology, ISSN 1664-042X, 09/2018, Volume 9, pp. 1223 - 1223
Planarians undergo continuous body size remodeling under starvation or during regeneration. This process likely involves autophagy and autophagic cell death,... 
Autophagic cell death | Regeneration | RNAi | Planarian | Autophagy | DjAtg7 | autophagic cell death | PHYSIOLOGY | autophagy | SEQUENCES | regeneration | SMALL-INTESTINE | MECHANISMS | MACROAUTOPHAGY | ALTERNATIVE AUTOPHAGY | planarian | GROWTH | STARVATION | PROTEINS | ATG7 | Autophagy (Cytology) | Genetic aspects | Platyhelminthes | Research | Cell death
Journal Article
by Zhang, P and Ren, LP and Song, GY and Zhang, L and Li, Y and Hou, GS and Chen, SC
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, ISSN 1940-5901, 2019, Volume 12, Issue 7, pp. 9116 - 9121
In the current study, we evaluated the serum levels of the autophagy indicators, autophagy-related protein 7 (Atg7) and Beclin-1, and the possible association... 
Beclin-1 | MEDICINE, RESEARCH & EXPERIMENTAL | NAFLD | OBESITY | autophagy | INSULIN-RESISTANCE | GLUCOSE | Atg7 | STRESS | DEFICIENCY
Journal Article
Journal Article
Journal Article
Autophagy, ISSN 1554-8627, 12/2014, Volume 10, Issue 12, pp. 2208 - 2222
Dysregulation of autophagy contributes to neuronal cell death in several neurodegenerative and lysosomal storage diseases. Markers of autophagy are also... 
β; AIF1/IBA1, allograft inflammatory factor 1 | SPTAN1, spectrin, α, non-erythrocytic 1 | LAMP1, lysosomal-associated membrane protein 1 | LC3, microtubule associated protein 1 light chain 3 | ACTB, actin | APC, adenomatous polyposis coli | ATG7, autophagy-related 7 | ULK1, unc-51 like autophagy activating kinase 1 | AIFM1, apoptosis-inducing factor, mitochondrion-associated, 1 | ATG5, autophagy-related 5 | autophagy flux | CASP3, caspase 3 | GFP, green fluorescent protein | autophagy | traumatic brain injury | CSPG4, chondroitin sulfate proteoglycan 4 | CAPS12, caspase 12 | neuronal cell death | ATG12, autophagy-related 12 | SQSTM1, sequestosome 1 | CD68, CD68 molecule | CCI, controlled cortical impact | RBFOX3, RNA binding protein, fox-1 homolog (C. elegans) 3 | LAMP2, lysosomal-associated membrane protein 2 | TBI, traumatic brain injury | lysosome | CTSD, cathepsin D | Traumatic brain injury | Autophagy | Neuronal cell death | Autophagy flux | Lysosome | NEURODEGENERATIVE DISEASE | UBIQUITIN | LYSOSOMAL STORAGE DISORDERS | CEREBRAL-CORTEX | RAT MODEL | CELL BIOLOGY | PATHWAY | DEGRADATION | MICE | EXPRESSION | PARKINSONS-DISEASE | Sequestosome-1 Protein | Heat-Shock Proteins - metabolism | Mice, Inbred C57BL | Phagosomes - metabolism | Neurons - cytology | Autophagy - physiology | Brain Injuries - metabolism | Apoptosis Regulatory Proteins - metabolism | Brain - metabolism | Animals | Cell Death - physiology | Neurons - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Brain Injuries - pathology | Disease Models, Animal | Index Medicus
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 06/2018, Volume 47, Issue 2, pp. 654 - 666
Background/Aims: Ubiquitin E3 ligase MARCH7 plays an important role in T cell proliferation and neuronal development. But its role in ovarian cancer remains... 
Original Paper | Smad2/3 | March7 | MALAT1 | ATG7 | Autophagy | Invasion | Ovarian cancer | MIGRATION | BLADDER-CANCER | PHYSIOLOGY | TGF-BETA | METASTASIS | CELL INVASION | RECEPTOR | PROLIFERATION | CELL BIOLOGY | INHIBITION | PATHWAY | EXPRESSION | MicroRNAs - antagonists & inhibitors | Autophagy-Related Protein 7 - metabolism | Humans | Ovarian Neoplasms - pathology | Ubiquitin-Protein Ligases - antagonists & inhibitors | MicroRNAs - metabolism | Autophagy - drug effects | Receptor, Transforming Growth Factor-beta Type II | RNA Interference | Female | Ovarian Neoplasms - metabolism | Protein-Serine-Threonine Kinases - metabolism | Autophagy-Related Protein 7 - antagonists & inhibitors | Ubiquitin-Protein Ligases - metabolism | RNA, Long Noncoding - genetics | Autophagy-Related Protein 7 - genetics | Cell Movement - drug effects | Transforming Growth Factor beta - pharmacology | Animals | Receptors, Transforming Growth Factor beta - metabolism | Mice, Nude | Cell Line, Tumor | Mice | Mice, Inbred BALB C | MicroRNAs - genetics | Antagomirs - metabolism | RNA, Long Noncoding - antagonists & inhibitors | Ubiquitin-Protein Ligases - genetics | RNA, Long Noncoding - metabolism | Smad Proteins - metabolism | RNA, Small Interfering - metabolism | Biotechnology | Immunoglobulins | Metastasis | Hybridization | Gene expression | Kinases | Proteins | Cell cycle | Protein expression | Growth factors | Apoptosis | Index Medicus
Journal Article
Autophagy, ISSN 1554-8627, 11/2014, Volume 10, Issue 11, pp. 1883 - 1894
Journal Article
Autophagy, ISSN 1554-8627, 01/2015, Volume 11, Issue 1, pp. 60 - 74
Journal Article
Autophagy, ISSN 1554-8627, 04/2015, Volume 11, Issue 4, pp. 670 - 684
Autophagy is a critical cellular homeostatic process that controls the turnover of damaged organelles and proteins. Impaired autophagic activity is involved in... 
CASP3, caspase 3, apoptosis-related cysteine peptidase | MAP1LC3B/LC3B, microtubule-associated protein 1 light chain 3 β | TUBB4, tubulin, β 4, class IV | DRAM2, DNA-damage regulated autophagy modulator 2 | IL13, interleukin 13 | CAV1, caveolin 1, caveolae protein, 22kDa | CCL3, chemokine (C-C motif) ligand 3 | ATG9B, autophagy-related 9B | RELA, v-rel reticuloendotheliosis viral oncogene homolog A | TGFB1, transforming growth factor, β 1 | ATG4B, autophagy-related 4B | epithelial cell | ATG3, autophagy-related 3 | CXCR2, chemokine (C-X-C motif) receptor 2 | lung fibrosis | IFNG, interferon, gamma | ATG7, autophagy-related 7 | ATG5, autophagy-related 5 | CXCL1, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity α) | autophagin-1 | GFP-LC3B, green fluorescent protein-LC3B | TGFBR2, transforming growth factor, β receptor II (70/80kDa) | autophagy | TNF, tumor necrosis factor | IL12B, interleukin 12B | WT, wild type | idiopathic pulmonary fibrosis | IPF, idiopathic pulmonary fibrosis | SQSTM1, sequestosome 1 | ACTA2, actin, α 2, smooth muscle, aorta | BAX, BCL2-associated X protein | ATG4B | cysteine peptidase | Epithelial cell | Autophagin-1 | Autophagy | Idiopathic pulmonary fibrosis | Lung fibrosis | APOPTOSIS | LUNG INJURY | RECEPTOR | CELL BIOLOGY | DISEASES | EPITHELIAL-CELLS | IL-17A PROMOTES | INFLAMMATION | MICE | EXPRESSION | CAVEOLIN-1 | Autophagy-Related Proteins | Cytokines - metabolism | Gene Expression - drug effects | Epithelial Cells - drug effects | Apoptosis - genetics | Autophagy - physiology | Idiopathic Pulmonary Fibrosis - chemically induced | Autophagy - drug effects | Idiopathic Pulmonary Fibrosis - metabolism | Mice, Knockout | Animals | Cysteine Endopeptidases - metabolism | Cysteine Endopeptidases - genetics | Bleomycin - pharmacology | Homeostasis - drug effects | Epithelial Cells - cytology | Cytokines - genetics | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2016, Volume 113, Issue 1, pp. 182 - 187
Journal Article