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International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 06/2014, Volume 51, Issue 1, pp. 111 - 119
Journal Article
Cancer Letters, ISSN 0304-3835, 2014, Volume 350, Issue 1, pp. 61 - 68
Journal Article
Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 28, pp. 26142 - 26160
ABCB1-mediated multidrug resistance (MDR) remains a major obstacle to successful chemotherapy in ovarian cancer. Herein, afatinib at nontoxic concentrations... 
ABCB1 | Afatinib | Tyrosine kinase inhibitor | Multidrug resistance | Ovarian cancer | VITRO | multidrug resistance | ovarian cancer | TYROSINE KINASE | PHASE-II | POTENT MODULATOR | P-GLYCOPROTEIN | CELL BIOLOGY | afatinib | IN-VIVO REVERSAL | DRUG TRANSPORTERS | EFFLUX | LEUKEMIA-CELLS | tyrosine kinase inhibitor | EXPRESSION
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 08/2014, Volume 115, Issue 8, pp. 1381 - 1391
Journal Article
Journal Article
Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 06/2013, Volume 49, Issue 3, pp. 441 - 450
Journal Article
Atherosclerosis, ISSN 0021-9150, 2017, Volume 258, pp. 56 - 64
Abstract Background and aims Apple polyphenol contains abundant procyanidins, which have been associated with an anti-atherosclerosis and cholesterol-lowering... 
Cardiovascular | ATP-binding cassette | Apple polyphenol | Atherosclerotic plaque regression | Anti-oxidant effect | Apple procyanidins | Subfamily A member 1 | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | METAANALYSIS | MACROPHAGES | RISK | IN-VITRO | POLYPHENOLS | CHOLESTEROL EFFLUX | ENDOTHELIAL-CELLS | PERIPHERAL VASCULAR DISEASE | MICE | LDL OXIDATION | Biflavonoids - pharmacology | Up-Regulation | Cholesterol - blood | Male | Aorta - metabolism | RNA, Messenger - metabolism | ATP Binding Cassette Transporter 1 - metabolism | Aortic Diseases - metabolism | Proanthocyanidins - pharmacology | Time Factors | ATP Binding Cassette Transporter 1 - agonists | Aortic Diseases - prevention & control | Phytotherapy | Catechin - pharmacology | Aortic Diseases - pathology | Disease Models, Animal | Atherosclerosis - pathology | Reactive Oxygen Species - blood | Fruit - chemistry | Aorta - drug effects | Malus - chemistry | RNA, Messenger - genetics | Plaque, Atherosclerotic | Atherosclerosis - metabolism | Cardiovascular Agents - pharmacology | Aorta - pathology | Scavenger Receptors, Class E - metabolism | Biflavonoids - isolation & purification | Animals | Cardiovascular Agents - isolation & purification | Catechin - isolation & purification | Oxidative Stress - drug effects | Atherosclerosis - prevention & control | Lipoproteins, LDL - blood | Plants, Medicinal | Proanthocyanidins - isolation & purification | ATP Binding Cassette Transporter 1 - genetics | Medical colleges | Atherosclerosis | Anticholesteremic agents | Blood lipids | Analysis
Journal Article
Oncology Letters, ISSN 1792-1074, 02/2018, Volume 15, Issue 2, pp. 2651 - 2654
In the past decades, the tricyclic acridone ring system has become a focus of major research by medicinal chemists due to the biological significance of this... 
Human breast cancer | ATP-binding cassette subfamily G member 2 | MDA-MB-231 | Acridone | acridone | SUBTYPES | DRUG-RESISTANCE | HER-2 | ESTROGEN-RECEPTOR | CHEMOTHERAPY | ONCOLOGY | human breast cancer | PROGESTERONE-RECEPTOR | MULTIDRUG-RESISTANCE | DERIVATIVES | ALKALOIDS
Journal Article
Journal of Biomolecular Screening, ISSN 1087-0571, 1/2013, Volume 18, Issue 1, pp. 26 - 38
Chemotherapeutics tumor resistance is a principal reason for treatment failure, and clinical and experimental data indicate that multidrug transporters such as... 
efflux inhibition | multidrug resistance | ABCB1 | ABC transporter | ABCG2 | VITRO | CHEMISTRY, ANALYTICAL | MEDIATED MULTIDRUG-RESISTANCE | BIOCHEMICAL RESEARCH METHODS | POTENT MODULATOR | DRUG-RESISTANCE | CELL-LINES | CHEMOTHERAPY | BREAST-CANCER | IN-VIVO REVERSAL | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | FUMITREMORGIN-C | P-GLYCOPROTEIN INHIBITION | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Cell Line | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Drug Resistance, Neoplasm | Neoplasm Proteins - antagonists & inhibitors | Structure-Activity Relationship | Pyrimidines - pharmacology | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Mice, SCID | Neoplasm Proteins - metabolism | Xenograft Model Antitumor Assays | Animals | Flow Cytometry | High-Throughput Screening Assays | Tumor Burden - drug effects | Small Molecule Libraries | ATP-Binding Cassette Transporters - metabolism | Inhibitory Concentration 50 | ATP Binding Cassette Transporter, Sub-Family B | Antineoplastic Agents - pharmacology | Mice | ATP-Binding Cassette Transporters - antagonists & inhibitors | Pyrazoles - pharmacology | Genetic aspects | Adenosine triphosphatase genes | High-throughput screening (Biochemical assaying) | Analysis | Tumors | mitoxantrone | Flow cytometry | Therapeutic applications | Cytotoxicity | Data processing | Topotecan | Models | Structure-activity relationships | Probes
Journal Article