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1. Full Text HDL Particle Size Is a Critical Determinant of ABCA1-Mediated Macrophage Cellular Cholesterol Export
by Du, Xian-Ming and Kim, Mi-Jurng and Hou, Liming and Le Goff, Wilfried and Chapman, M John and Van Eck, Miranda and Curtiss, Linda K and Burnett, John R and Cartland, Sian P and Quinn, Carmel M and Kockx, Maaike and Kontush, Anatol and Rye, Kerry-Anne and Kritharides, Leonard and Jessup, Wendy
Circulation research, ISSN 0009-7330, 03/2015, Volume 116, Issue 7, pp. 1133 - 1142
foam cells | HDL | ATP-binding cassette transporters | macrophages | cholesterol, HDL | ATP binding cassette transporter 1 | Cholesterol | cholesterol-efflux regulatory protein | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Lipoproteins - deficiency | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Cricetulus | Humans | Lipoproteins, HDL - metabolism | ATP-Binding Cassette Transporters - physiology | Recombinant Fusion Proteins - metabolism | ATP-Binding Cassette Transporters - deficiency | ATP Binding Cassette Transporter 1 - physiology | Biological Transport | Foam Cells - metabolism | Lipoproteins, HDL2 - metabolism | CHO Cells | Cell Line | Cricetinae | Tangier Disease - enzymology | Tangier Disease - genetics | Cholesterol, HDL - metabolism | Mice, Inbred C57BL | Gene Silencing | Apolipoprotein A-I - metabolism | Cholesterol - metabolism | Lipoproteins - physiology | Mice, Knockout | Particle Size | Macrophages - metabolism | Animals | ATP Binding Cassette Transporter 1 - deficiency | ATP Binding Cassette Transporter 1 - antagonists & inhibitors | Mice | ATP Binding Cassette Transporter 1 - genetics | Index Medicus
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2. Full Text Mechanistic diversity in ATP-binding cassette (ABC) transporters
by Locher, Kaspar P
Nature structural & molecular biology, ISSN 1545-9993, 06/2016, Volume 23, Issue 6, pp. 487 - 493
Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Catalytic Domain | Gene Expression | Bacteria - chemistry | Protein Structure, Secondary | Humans | Models, Molecular | Protein Folding | Hydrolysis | ATP-Binding Cassette Transporters - chemistry | ATP-Binding Cassette Transporters - classification | Animals | ATP-Binding Cassette Transporters - genetics | Biological Transport | Adenosine Triphosphate - metabolism | ATP-Binding Cassette Transporters - metabolism | Protein Binding | Protein Domains | Adenosine Triphosphate - chemistry | Proteins | Carrier proteins | Analysis | Properties | Observations | Structure | Protein-protein interactions | Membranes | ABC transporters | Biochemistry | Index Medicus
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3. Full Text Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice
by Yvan-Charvet, Laurent and Ranalletta, Mollie and Wang, Nan and Han, Seongah and Terasaka, Naoki and Li, Rong and Welch, Carrie and Tall, Alan R
The Journal of clinical investigation, ISSN 0021-9738, 12/2007, Volume 117, Issue 12, pp. 3900 - 3908
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Lipoproteins, HDL - genetics | Lipoproteins - genetics | Atherosclerosis - genetics | Lipoproteins, HDL - metabolism | Lipoproteins, LDL - genetics | Apolipoproteins E - metabolism | Cholesterol - genetics | Apolipoprotein A-I - genetics | ATP-Binding Cassette Transporters - genetics | Myocardium - metabolism | Lipoproteins - metabolism | ATP-Binding Cassette Transporters - metabolism | Lipoproteins, LDL - metabolism | ATP Binding Cassette Transporter 1 | Spleen - pathology | Foam Cells - pathology | Foam Cells - metabolism | Atherosclerosis - pathology | Myocardium - pathology | Apolipoprotein A-I - metabolism | Cholesterol - metabolism | Atherosclerosis - metabolism | Mice, Knockout | Animals | Spleen - metabolism | Apolipoproteins E - genetics | Mice | High density lipoproteins | Atherosclerosis | Genetic aspects | Research | Protein deficiency | Health aspects | Risk factors | Index Medicus | Abridged Index Medicus
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4. Full Text Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels
by Shawahna, Ramzi and Uchida, Yasuo and Declèves, Xavier and Ohtsuki, Sumio and Yousif, Salah and Dauchy, Sandrine and Jacob, Aude and Chassoux, Francine and Daumas-Duport, Catherine and Couraud, Pierre-Olivier and Terasaki, Tetsuya and Scherrmann, Jean-Michel
Molecular pharmaceutics, ISSN 1543-8384, 08/2011, Volume 8, Issue 4, pp. 1332 - 1341
blood-brain barrier | quantitative LC-MS/MS | transporters | drug-metabolizing enzymes | human | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Glutamate Plasma Membrane Transport Proteins - metabolism | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Microvessels - metabolism | Glucose Transporter Type 1 - metabolism | Glutamate Plasma Membrane Transport Proteins - genetics | Excitatory Amino Acid Transporter 1 - genetics | Neoplasm Proteins - metabolism | Brain - metabolism | Brain - blood supply | Tandem Mass Spectrometry | Glutathione Transferase - genetics | ATP-Binding Cassette Transporters - genetics | ATP-Binding Cassette Transporters - metabolism | Chromatography, Liquid | Proteomics - methods | Neoplasm Proteins - genetics | Transcriptome - physiology | Glutathione S-Transferase pi - genetics | Glutathione S-Transferase pi - metabolism | Glutathione Transferase - metabolism | Excitatory Amino Acid Transporter 1 - metabolism | Transcriptome - genetics | Glucose Transporter Type 1 - genetics | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | ATP Binding Cassette Transporter, Sub-Family B | In Vitro Techniques | Index Medicus
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5. Full Text TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis
by Hsieh, Joanne and Koseki, Masahiro and Molusky, Matthew M and Yakushiji, Emi and Ichi, Ikuyo and Westerterp, Marit and Iqbal, Jahangir and Chan, Robin B and Abramowicz, Sana and Tascau, Liana and Takiguchi, Shunichi and Yamashita, Shizuya and Welch, Carrie L and Di Paolo, Gilbert and Hussain, M Mahmood and Lefkowitch, Jay H and Rader, Daniel J and Tall, Alan R
Nature (London), ISSN 0028-0836, 07/2016, Volume 535, Issue 7611, pp. 303 - 307
Fatty Liver/genetics | Cholesterol, HDL/metabolism | Atherosclerosis/genetics | Male | Lipoproteins, HDL/deficiency | Ubiquitination | Proteolysis | Diet, High-Fat | Liver X Receptors | Female | Protein Stability | Cholesterol, Dietary/metabolism | Lipogenesis/genetics | Orphan Nuclear Receptors/genetics | Receptors, LDL/deficiency | Gene Expression Regulation | Lipoproteins, LDL/metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 5 | ATP-Binding Cassette Transporters/metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 8 | Sterol Regulatory Element Binding Protein 1/metabolism | Lipoproteins/metabolism | Phosphatidylcholines/biosynthesis | Animals | Hepatocytes/metabolism | Fatty Acids, Unsaturated/metabolism | Ligands | ATP Binding Cassette Transporter 1/metabolism | Mice | Bile Acids and Salts/metabolism | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Lipoproteins, HDL - genetics | Atherosclerosis - genetics | Cholesterol, Dietary - metabolism | Phosphatidylcholines - biosynthesis | Lipoproteins, HDL - metabolism | Fatty Liver - therapy | Hepatocytes - metabolism | Orphan Nuclear Receptors - metabolism | Phosphatidylcholines - metabolism | ATP Binding Cassette Transporter 1 - metabolism | Atherosclerosis - therapy | Lipogenesis - genetics | Lipoproteins - metabolism | Receptors, LDL - deficiency | ATP-Binding Cassette Transporters - metabolism | Lipoproteins, HDL - deficiency | Lipoproteins, LDL - metabolism | Sterol Regulatory Element Binding Protein 1 - metabolism | Fatty Liver - genetics | Receptors, LDL - genetics | Cholesterol, HDL - metabolism | Fatty Liver - prevention & control | Bile Acids and Salts - metabolism | Fatty Acids, Unsaturated - metabolism | Orphan Nuclear Receptors - genetics | ATP Binding Cassette Transporter, Sub-Family G, Member 8 | Atherosclerosis - prevention & control | ATP Binding Cassette Transporter, Sub-Family G, Member 5 | Proteolipids | Transcription factors | Lipoproteins | Liver diseases | Atherosclerosis | Genetic aspects | Blood lipoproteins | Properties | Ubiquitin-proteasome system | Health aspects | Risk factors | Proteins | Diet | Liver | Gene expression | Cholesterol | Index Medicus
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6. Full Text Apolipoprotein AI and High-Density Lipoprotein Have Anti-Inflammatory Effects on Adipocytes via Cholesterol Transporters: ATP-Binding Cassette A-1, ATP-Binding Cassette G-1, and Scavenger Receptor B-1
by Umemoto, Tomio and Han, Chang Yeop and Mitra, Poulami and Averill, Michelle M and Tang, Chongren and Goodspeed, Leela and Omer, Mohamed and Subramanian, Savitha and Wang, Shari and Den Hartigh, Laura J and Wei, Hao and Kim, Eung Ju and Kim, Jinkyu and O’Brien, Kevin D and Chait, Alan
Circulation research, ISSN 0009-7330, 05/2013, Volume 112, Issue 10, pp. 1345 - 1354
Apolipoprotein AI | HDL | ABC transporters | Adipocytes | Cholesterol | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Apolipoprotein A-I - pharmacology | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Reactive Oxygen Species - metabolism | Humans | Lipoproteins, HDL - metabolism | Adipocytes - cytology | Male | Adipocytes - drug effects | Lipoproteins, HDL - pharmacology | Apolipoprotein A-I - genetics | Inflammation - metabolism | Lipoproteins - metabolism | Receptors, LDL - deficiency | ATP-Binding Cassette Transporters - metabolism | ATP Binding Cassette Transporter 1 | Scavenger Receptors, Class B - drug effects | Disease Models, Animal | Receptors, LDL - genetics | Anti-Inflammatory Agents - pharmacology | Mice, Inbred C57BL | RNA, Small Interfering - pharmacology | Cells, Cultured | Receptors, LDL - metabolism | Mice, Transgenic | Apolipoprotein A-I - metabolism | 3T3-L1 Cells | Cholesterol - metabolism | Mice, Knockout | Animals | ATP-Binding Cassette Transporters - drug effects | Membrane Microdomains - drug effects | Adipocytes - metabolism | Biological Transport - physiology | Mice | Lipoproteins - drug effects | Scavenger Receptors, Class B - metabolism | In Vitro Techniques | Index Medicus
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7. Full Text Activation of liver X receptor decreases atherosclerosis in Ldlr⁻/⁻ mice in the absence of ATP-binding cassette transporters A1 and G1 in myeloid cells
by Kappus, Mojdeh S and Murphy, Anew J and Abramowicz, Sana and Ntonga, Vusisizwe and Welch, Carrie L and Tall, Alan R and Westerterp, Marit
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 2014, Volume 34, Issue 2, pp. 279 - 284
atherosclerosis | ATP-binding cassette transporters | macrophages | liver X receptor | inflammation | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Lipoproteins - deficiency | Macrophages - transplantation | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Lipoproteins - genetics | Atherosclerosis - genetics | Hydrocarbons, Fluorinated - pharmacology | Male | Aorta - metabolism | Orphan Nuclear Receptors - metabolism | ATP-Binding Cassette Transporters - deficiency | ATP-Binding Cassette Transporters - genetics | Biological Transport | Liver X Receptors | Myocardium - metabolism | Bone Marrow Transplantation | Inflammation Mediators - metabolism | Receptors, LDL - deficiency | Female | Cytokines - genetics | Macrophages - immunology | Disease Models, Animal | Receptors, LDL - genetics | Atherosclerosis - pathology | Atherosclerosis - immunology | Cytokines - metabolism | Anti-Inflammatory Agents - pharmacology | Aorta - drug effects | Mice, Inbred C57BL | Orphan Nuclear Receptors - agonists | Gene Expression Regulation | Myocardium - pathology | Cholesterol - metabolism | Sulfonamides - pharmacology | Atherosclerosis - metabolism | Mice, Knockout | Aorta - pathology | Macrophages - metabolism | Animals | Lipopolysaccharides - pharmacology | ATP Binding Cassette Transporter 1 - deficiency | Benzoates - pharmacology | Macrophages - drug effects | Mice | Benzylamines - pharmacology | Atherosclerosis - prevention & control | ATP Binding Cassette Transporter 1 - genetics | Index Medicus
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8. Full Text MicroRNA-19b promotes macrophage cholesterol accumulation and aortic atherosclerosis by targeting ATP-binding cassette transporter A1
by Lv, Yun-Cheng and Tang, Yan-Yan and Peng, Juan and Zhao, Guo-Jun and Yang, Jing and Yao, Feng and Ouyang, Xin-Ping and He, Ping-Ping and Xie, Wei and Tan, Yu-Lin and Zhang, Min and Liu, Dan and Tang, Deng-Pei and Cayabyab, Francisco S and Zheng, Xi-Long and Zhang, Da-Wei and Tian, Guo-Ping and Tang, Chao-Ke
Atherosclerosis, ISSN 0021-9150, 2014, Volume 236, Issue 1, pp. 215 - 226
Cardiovascular | ABCA1 | Cholesterol accumulation | MiR-19b | Atherosclerosis | Macrophage | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cholesterol Esters - metabolism | Apolipoproteins E - deficiency | Atherosclerosis - genetics | Molecular Sequence Data | Male | RNA, Messenger - metabolism | Aortic Diseases - metabolism | Atherosclerosis - etiology | ATP Binding Cassette Transporter 1 - physiology | Base Sequence | Foam Cells - metabolism | Cell Line | Plaque, Atherosclerotic - metabolism | Apolipoprotein A-I - metabolism | Cholesterol - metabolism | Sequence Homology, Nucleic Acid | Atherosclerosis - metabolism | Mice, Knockout | Aortic Diseases - genetics | Macrophages - metabolism | Animals | ATP Binding Cassette Transporter 1 - antagonists & inhibitors | Mice | Collagen - analysis | MicroRNAs - physiology | Macrophages, Peritoneal - metabolism | Aortic Diseases - etiology | ATP Binding Cassette Transporter 1 - genetics | MicroRNA | Chemical properties | Macrophages | Cholesterol | Analysis | Index Medicus
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9. Full Text A Member of the PLEIOTROPIC DRUG RESISTANCE Family of ATP Binding Cassette Transporters Is Required for the Formation of a Functional Cuticle in Arabidopsis
by Michael Bessire and Sandra Borel and Guillaume Fabre and Luis Carraca and Nadia Efremova and Alexander Yephremov and Yan Cao and Reinhard Jetter and Anne-Claude Jacquat and Jean-Pierre Métraux and Christiane Nawrath
The Plant cell, ISSN 1040-4651, 5/2011, Volume 23, Issue 5, pp. 1958 - 1970
ATP binding cassette transporters | Petals | Plant cuticle | Epidermal cells | Animal cuticle | Plants | Flowers | Stems | Monomers | Plant cells | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Plant Sciences | Science & Technology | Cell Biology | Cell Membrane | Sequence Deletion | Flowers - metabolism | Flowers - ultrastructure | Plant Epidermis - metabolism | Arabidopsis Proteins - metabolism | ATP-Binding Cassette Transporters - genetics | Gene Expression Regulation, Plant | ATP-Binding Cassette Transporters - metabolism | ATP Binding Cassette Transporter 1 | Arabidopsis Proteins - genetics | Plants, Genetically Modified - genetics | Arabidopsis - ultrastructure | Genotype | Permeability | Arabidopsis - metabolism | Arabidopsis - genetics | Phenotype | Plants, Genetically Modified - metabolism | Plant Leaves - genetics | Plant Leaves - metabolism | Cell Wall - metabolism | Membrane Lipids - metabolism | ATP Binding Cassette Transporter, Sub-Family G | Flowers - genetics | Plant Leaves - ultrastructure | Arabidopsis thaliana | Physiological aspects | Genetic aspects | Research | Drug resistance | Health aspects | Adenosine triphosphate | Index Medicus
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