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Journal Article
Nature (London), ISSN 1476-4687, 2017, Volume 546, Issue 7659, pp. 504 - 509
Journal Article
Drug Metabolism and Pharmacokinetics, ISSN 1347-4367, 2014, Volume 29, Issue 6, pp. 490 - 492
Journal Article
Cancer research (Chicago, Ill.), ISSN 1538-7445, 2008, Volume 68, Issue 19, pp. 7905 - 7914
...) due to overexpression of ABC subfamily B member 1 (ABCB1) and ABC subfamily G member 2 (ABCG2) transporters... 
BREAST-CANCER | ACQUIRED MUTATIONS | IN-VITRO | HUMAN P-GLYCOPROTEIN | ONCOLOGY | METHOTREXATE TRANSPORT | TYROSINE KINASE INHIBITOR | DRUG-RESISTANCE | PHASE-I | CATALYTIC CYCLE | ABCG2 | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Neoplasms - metabolism | Drug Resistance, Multiple - drug effects | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Adenosine Triphosphatases - drug effects | Quinazolines - pharmacokinetics | Neoplasm Proteins - antagonists & inhibitors | Paclitaxel - pharmacokinetics | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Neoplasm Proteins - metabolism | Dose-Response Relationship, Drug | Transfection | ATP-Binding Cassette Transporters - genetics | Neoplasms - genetics | Up-Regulation - physiology | ATP-Binding Cassette Transporters - metabolism | Quinazolines - administration & dosage | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Paclitaxel - administration & dosage | Drug Resistance, Multiple - genetics | Cells, Cultured | Adenosine Triphosphatases - metabolism | Neoplasms - drug therapy | Up-Regulation - drug effects | Xenograft Model Antitumor Assays | Drug Resistance, Neoplasm - genetics | Animals | Tumor Burden - drug effects | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Mice, Nude | ATP Binding Cassette Transporter, Sub-Family B | Mice | Neoplasms - pathology | Quinazolines - pharmacology | ATP-Binding Cassette Transporters - antagonists & inhibitors | Drug Resistance, Neoplasm - drug effects | BCRP | multidrug resistance | ABCB1 | P-gp | MXR | lapatinib | EGFR tyrosine kinase inhibitor
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 2007, Volume 117, Issue 12, pp. 3900 - 3908
Journal Article
Toxicology and applied pharmacology, ISSN 0041-008X, 2005, Volume 204, Issue 3, pp. 216 - 237
In tumor cell lines, multidrug resistance is often associated with an ATP-dependent decrease in cellular drug accumulation which is attributed to the overexpression of certain ATP-binding cassette (ABC... 
P-glycoprotein | BCRP | ATP-binding cassette transporters | Chemical toxicity | Carcinogen transport | MRP | Tissue defense | Heavy metal transport | CONJUGATE EXPORT PUMP | ORGANIC ANION TRANSPORTER | KIDNEY PROXIMAL TUBULES | FOOD-DERIVED CARCINOGEN | HUMAN LUNG-CANCER | carcinogen transport | chemical toxicity | BLOOD-BRAIN-BARRIER | AMINO-ACID RESIDUE | heavy metal transport | ATP-BINDING CASSETTE | FUNCTIONAL EXPRESSION | tissue defense | PHARMACOLOGY & PHARMACY | TOXICOLOGY | SINGLE-NUCLEOTIDE POLYMORPHISMS | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Neoplasm Proteins - biosynthesis | Humans | Neoplasm Proteins - physiology | ATP Binding Cassette Transporter, Sub-Family B - physiology | ATP-Binding Cassette, Sub-Family B, Member 1 - biosynthesis | Multidrug Resistance-Associated Proteins - biosynthesis | ATP-Binding Cassette Transporters - physiology | ATP-Binding Cassette, Sub-Family B, Member 1 - physiology | Membrane Transport Proteins - physiology | ATP-Binding Cassette Transporters - biosynthesis | Pregnancy | Tissue Distribution | Membrane Transport Proteins - biosynthesis | Animals | ATP Binding Cassette Transporter, Sub-Family B - biosynthesis | Drug-Related Side Effects and Adverse Reactions | Multidrug Resistance-Associated Proteins - physiology | Female | ANIONS | MAMMARY GLANDS | NEOPLASMS | LUNGS | PLACENTA | CARCINOGENS | GLYCOPROTEINS | TOXINS | BLOOD-BRAIN BARRIER | TOXICITY | TUMOR CELLS | EXCRETION | 60 APPLIED LIFE SCIENCES | KIDNEYS | METABOLISM | TISSUE DISTRIBUTION | DRUGS | GENES | LIVER | BLOOD | LIPIDS
Journal Article
Biochimica et biophysica acta. Molecular and cell biology of lipids, ISSN 1388-1981, 2009, Volume 1791, Issue 7, pp. 584 - 593
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2011, Volume 108, Issue 49, pp. 19719 - 19724
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 11/2017, Volume 45, Issue 11, pp. 1166 - 1177
Journal Article