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Cancer Research, ISSN 0008-5472, 10/2010, Volume 70, Issue 20, pp. 7981 - 7991
Journal Article
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 06/2017, Volume 1862, Issue 6, pp. 573 - 588
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 08/2009, Volume 26, Issue 8, pp. 1816 - 1831
To study the inhibition patterns of the three major human ABC transporters P-gp (ABCB1), BCRP (ABCG2) and MRP2 (ABCC2), using a dataset of 122 structurally... 
Drug transport | ABC transporters | Transport proteins | Inhibition | Structure-activity relationships | COMPUTATIONAL MODELS | GLYCOPROTEIN INHIBITORS | drug transport | inhibition | CELL-LINES | BLOOD-BRAIN-BARRIER | CHEMISTRY, MULTIDISCIPLINARY | NORMAL HUMAN-TISSUES | IN-VITRO | structure-activity relationships | PHARMACOLOGY & PHARMACY | FUMITREMORGIN-C | MULTIDRUG-RESISTANCE | transport proteins | CANCER RESISTANCE PROTEIN | PHARMACOPHORE MODEL | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Propionates - pharmacology | Cell Line | Tetrahydroisoquinolines - pharmacology | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Multidrug Resistance-Associated Proteins - antagonists & inhibitors | Neoplasm Proteins - antagonists & inhibitors | Adenosine - pharmacology | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Neoplasm Proteins - metabolism | Diketopiperazines | Quinolines - pharmacology | Heterocyclic Compounds, 4 or More Rings | Acridines - pharmacology | Adenosine - analogs & derivatives | Adenosine Triphosphate - metabolism | Computer Simulation | ATP-Binding Cassette Transporters - metabolism | Multidrug Resistance-Associated Proteins - metabolism | ATP-Binding Cassette Transporters - antagonists & inhibitors | Drugs | Universities and colleges | Carrier proteins | Analysis | Pharmacy | Comparative studies | Medical research | Pharmacology | Inhibitor drugs | Binding sites | Index Medicus | Pharmaceutical Sciences | Basic Medicine | PHARMACY | Medical and Health Sciences | Medicin och hälsovetenskap | Farmaceutiska vetenskaper | Medicinska och farmaceutiska grundvetenskaper | FARMACI
Journal Article
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 11/2017, Volume 45, Issue 11, pp. 1166 - 1177
Multidrug resistance (MDR) caused by the overexpression of ATP-binding cassette (ABC) transporters in cancer cells is a major obstacle in cancer chemotherapy.... 
VITRO | CELLS | ABCB1 | HUMAN P-GLYCOPROTEIN | TURMERIC POWDER | IN-VIVO | PHARMACOLOGY & PHARMACY | CHEMOPREVENTIVE AGENT CURCUMIN | BIOCHEMICAL-MECHANISM | CANCER | PROTEIN-1 ABCC1 | Curcumin - analogs & derivatives | Humans | Biological Availability | Neoplasm Proteins - antagonists & inhibitors | Prazosin - analogs & derivatives | Neoplasm Proteins - metabolism | Azides - chemistry | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - metabolism | Flow Cytometry | Biological Transport | Antineoplastic Agents - pharmacology | Benzene Derivatives | Camptothecin - analogs & derivatives | Ketones | Curcumin - pharmacology | Neoplasm Proteins - chemistry | Prazosin - chemistry | Drug Synergism | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - antagonists & inhibitors | ATP Binding Cassette Transporter, Sub-Family B - metabolism | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - chemistry | Cell Line, Tumor | Mitoxantrone - pharmacokinetics | Camptothecin - pharmacology | Drug Resistance, Neoplasm - drug effects | Efflux | Flow cytometry | Toxicity | Multidrug resistance | Cytotoxicity | Breast cancer | Bioavailability | Substrates | Modulators | Analogs | Cytometry | Chemotherapy | Diet | Curcumin | Mitoxantrone | ATP | Transporter | Binding sites | Adenosine triphosphatase | Cancer | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2011, Volume 108, Issue 49, pp. 19719 - 19724
Four members of the mammalian ATP binding cassette (ABC) transporter G subfamily are thought to be involved in transmembrane (TM) transport of sterols. The... 
ATP binding cassette transporters | COS cells | Sterols | Plasmids | HDL lipoproteins | Amino acids | Cell membranes | Repression | Cholesterols | Endosomes | 27-hydroxycholesterol | 25-hydroxycholesterol | Cholesterol | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | ATHEROSCLEROSIS | MEMBRANE-PROTEIN | PLASMA-MEMBRANE | HIGH-DENSITY-LIPOPROTEIN | SENSING DOMAIN | cholesterol | SCAP | CELLULAR CHOLESTEROL EFFLUX | ENDOPLASMIC-RETICULUM | ACCUMULATION | Sterols - metabolism | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Cricetulus | Lipoproteins - genetics | Humans | Cercopithecus aethiops | Molecular Sequence Data | Macrophages, Peritoneal - cytology | Endosomes - metabolism | Transfection | ATP-Binding Cassette Transporters - genetics | Biological Transport | HEK293 Cells | Lipoproteins - metabolism | ATP-Binding Cassette Transporters - metabolism | Sterol Regulatory Element Binding Protein 2 - metabolism | Macrophages, Peritoneal - drug effects | CHO Cells | Amino Acid Sequence | Cricetinae | Cells, Cultured | Blotting, Western | Sequence Homology, Amino Acid | Animals | Intracellular Space - metabolism | Benzoates - pharmacology | Mutation | Macrophages, Peritoneal - metabolism | Benzylamines - pharmacology | COS Cells | Research | Properties | Adenosine triphosphate | Protein binding | Proteins | Membranes | ABC transporters | Cells | Steroids | Index Medicus | Biological Sciences
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 09/2012, Volume 11, Issue 9, pp. 2033 - 2044
Journal Article
Journal Article