X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (5896) 5896
Publication (591) 591
Book Chapter (64) 64
Book Review (57) 57
Conference Proceeding (7) 7
Book / eBook (3) 3
Dissertation (3) 3
Data Set (2) 2
Paper (1) 1
Streaming Video (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (4099) 4099
index medicus (2547) 2547
animals (2466) 2466
p-glycoprotein (1938) 1938
atp-binding cassette transporters - genetics (1563) 1563
male (1483) 1483
female (1429) 1429
pharmacology & pharmacy (1354) 1354
atp-binding cassette transporters - metabolism (1277) 1277
mice (1021) 1021
biochemistry & molecular biology (1015) 1015
expression (1009) 1009
multidrug-resistance (955) 955
atp binding cassette transporter, subfamily b, member 1 - metabolism (947) 947
oncology (920) 920
multidrug resistance (850) 850
drug resistance (731) 731
proteins (708) 708
adult (698) 698
cancer (650) 650
middle aged (632) 632
gene expression (623) 623
atp binding cassette transporter, subfamily b, member 1 - genetics (568) 568
analysis (560) 560
rats (533) 533
molecular sequence data (523) 523
cell biology (520) 520
gene (507) 507
genetic aspects (504) 504
research (499) 499
drug resistance, multiple (485) 485
tumor cells, cultured (476) 476
cell line, tumor (474) 474
cell line (466) 466
biological transport (462) 462
transporter (458) 458
drug-resistance (440) 440
physiological aspects (439) 439
cells (435) 435
atp binding cassette transporter, subfamily b, member 1 (431) 431
abc transporter (429) 429
pharmacokinetics (427) 427
chemotherapy (426) 426
abc transporters (422) 422
aged (421) 421
mutation (420) 420
amino acid sequence (419) 419
antineoplastic agents - pharmacology (411) 411
neoplasm proteins - metabolism (399) 399
drug resistance, neoplasm (397) 397
neoplasm proteins - genetics (392) 392
article (391) 391
in-vitro (386) 386
genes (377) 377
genotype (348) 348
metabolism (342) 342
liver (341) 341
atp binding cassette transporter, sub-family g, member 2 (335) 335
multidisciplinary sciences (319) 319
dose-response relationship, drug (314) 314
cells, cultured (303) 303
transport (303) 303
protein (298) 298
atp-binding cassette transporters - physiology (296) 296
drug resistance in microorganisms (296) 296
polymorphism, single nucleotide (296) 296
phenotype (292) 292
liver - metabolism (290) 290
research article (289) 289
atp binding cassette transporter, subfamily b, member 1 - antagonists & inhibitors (287) 287
atp-binding cassette, sub-family b, member 1 - metabolism (286) 286
rna, messenger - metabolism (286) 286
abcg2 (283) 283
flow cytometry (276) 276
doxorubicin - pharmacology (275) 275
biomedicine (273) 273
atp-binding cassette, sub-family b, member 1 - genetics (267) 267
atp binding cassette subfamily b member 11 (264) 264
immunohistochemistry (264) 264
reverse transcriptase polymerase chain reaction (262) 262
atp-binding cassette transporters - chemistry (260) 260
pharmacology/toxicology (259) 259
adolescent (258) 258
identification (256) 256
immunology (255) 255
atp binding cassette transporter, subfamily b, member 1 - biosynthesis (252) 252
base sequence (251) 251
polymerase chain reaction (249) 249
transfection (249) 249
verapamil - pharmacology (249) 249
biophysics (247) 247
gene-expression (246) 246
hematology (245) 245
multidrug resistance-associated proteins - metabolism (244) 244
resistance (241) 241
mdr1 (240) 240
efflux (239) 239
multidrug resistance-associated proteins - genetics (239) 239
protein binding (239) 239
chemistry, multidisciplinary (237) 237
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (5900) 5900
Japanese (8) 8
Chinese (5) 5
Amharic (1) 1
German (1) 1
Polish (1) 1
Spanish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 09/2017, Volume 313, Issue 3, pp. F826 - F834
Accumulating data indicate that renal uric acid (UA) handling is altered in diabetes and by hypoglycemic agents. In addition, hyperinsulinemia is associated... 
Hyperinsulinemia | Urate transporters | Hypouricosuria | Kidney proximal tubule | PHYSIOLOGY | hyperinsulinemia | SGLT2 INHIBITOR | GOUT | RISK | LEVEL | EXCRETION | IDENTIFICATION | hypouricosuria | DIABETES-MELLITUS | RENAL HYPOURICEMIA | urate transporters | RESISTANCE | UROLOGY & NEPHROLOGY | kidney proximal tubule | HYPERTENSION | Kidney Tubules - physiopathology | Diabetes Mellitus, Experimental - drug therapy | Streptozocin | Diabetes Mellitus, Type 1 - metabolism | Male | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - metabolism | Uric Acid - urine | Renal Reabsorption - drug effects | Time Factors | Diabetes Mellitus, Type 1 - chemically induced | Diabetes Mellitus, Experimental - chemically induced | Diabetes Mellitus, Experimental - metabolism | Kidney Tubules - metabolism | Diabetes Mellitus, Experimental - physiopathology | Cell Line | Insulin - pharmacology | Glucosides - pharmacology | Uric Acid - metabolism | Kidney Tubules - drug effects | Sodium-Glucose Transporter 2 - metabolism | Diabetes Mellitus, Type 1 - physiopathology | Thiophenes - pharmacology | Renal Elimination - drug effects | Anion Transport Proteins - metabolism | Rats, Sprague-Dawley | Sodium-Glucose Transporter 2 - antagonists & inhibitors | Diabetes Mellitus, Type 1 - drug therapy | Hypoglycemic Agents - pharmacology | Blood Glucose - drug effects | Animals | Blood Glucose - metabolism | Carrier proteins | Physiological aspects | Physiological research | Uric acid | Research | G proteins | Insulin | Absorption (Physiology)
Journal Article
International Journal of Cancer, ISSN 0020-7136, 01/2012, Volume 130, Issue 1, pp. 223 - 233
Journal Article
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 12/2008, Volume 107, Issue 5, pp. 1358 - 1368
The human brain endothelial capillary cell line hCMEC/D3 has been developed recently as a model for the human blood‐brain barrier. In this study a further... 
transendothelial transport | p‐glycoprotein | blood‐brain barrier | ABCB1 | permeability | ABCG2 | p-glycoprotein | Transendothelial transport | Permeability | Blood-brain barrier | blood-brain barrier | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROSCIENCES | MICROVESSEL ENDOTHELIUM | TRANSFERRIN RECEPTOR | IN-VITRO MODEL | SITES | MULTIDRUG-RESISTANCE | ASTROCYTIC FACTORS | EXPRESSION | CULTURE MODEL | CANCER RESISTANCE PROTEIN | Flow Cytometry - methods | Humans | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | Brain - blood supply | ATP-Binding Cassette Transporters - genetics | Biological Transport | Sucrose - metabolism | ATP-Binding Cassette Transporters - metabolism | Multidrug Resistance-Associated Proteins - genetics | Receptors, Transferrin - genetics | Neoplasm Proteins - genetics | ATP Binding Cassette Transporter, Subfamily G, Member 2 | Cell Line | Brain - cytology | Endothelial Cells - metabolism | RNA, Messenger - genetics | Receptors, Transferrin - metabolism | ATP Binding Cassette Transporter, Subfamily B | ATP Binding Cassette Transporter, Subfamily B, Member 1 - genetics | Blood-Brain Barrier - metabolism | ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism | Analysis of Variance | Endothelial Cells - cytology | Midazolam - metabolism | Multidrug Resistance-Associated Proteins - metabolism | Proteins | Propranolol hydrochloride | Medical colleges | Brain | Transferrin | Messenger RNA | Analysis | Morphine | Oligosaccharides | Endothelium | Dyes and dyeing | Neurology | Cell culture | Biochemistry | Pharmacology
Journal Article
Nature, ISSN 0028-0836, 11/2018, Volume 563, Issue 7731, pp. 426 - 430
ABCG2 is a transporter protein of the ATP-binding-cassette (ABC) family that is expressed in the plasma membrane in cells of various tissues and tissue... 
BINDING CASSETTE TRANSPORTER | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | RESISTANCE-ASSOCIATED PROTEIN | MULTIDRUG-RESISTANCE | CANCER | RECONSTITUTION | P-GLYCOPROTEIN | Neoplasm Proteins - ultrastructure | ATP Binding Cassette Transporter, Subfamily G, Member 2 - metabolism | Humans | ATP Binding Cassette Transporter, Subfamily G, Member 2 - genetics | Mutant Proteins - genetics | Models, Molecular | Substrate Specificity | Mutant Proteins - metabolism | Neoplasm Proteins - chemistry | Neoplasm Proteins - metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 2 - ultrastructure | Cryoelectron Microscopy | Mutant Proteins - ultrastructure | Adenosine Triphosphate - metabolism | Mutant Proteins - chemistry | Protein Binding | Protein Conformation | Mutation | Neoplasm Proteins - genetics | Binding Sites | ATP Binding Cassette Transporter, Subfamily G, Member 2 - chemistry | Carrier proteins | Physiological aspects | Adenosine triphosphatase | Glutamine | Protein binding | Drugs | Brain | Antibodies | Leucine | Hydrophobicity | Tissues | Blood | Proteins | Hydrogen bonds | ABC transporters | Catalysis | Xenobiotics | Protein transport | Adenosine triphosphate | Symmetry | Binding | Translocation | Fetuses | Substrate inhibition | Pharmacology | Electron microscopy | Substrates | Domains | Microscopy | Mutagenesis | Ligands | Estrone | Transmembrane domains | Sulfate | Pharmacokinetics | Transport | ATP | Transporter | Binding sites | Cytoplasm | Recognition | Cancer
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2009, Volume 106, Issue 25, pp. 10338 - 10342
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 04/2012, Volume 83, Issue 8, pp. 1084 - 1103
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 03/2018, Volume 45, Issue 4, pp. 1515 - 1528
Background/Aims: The overexpression of ATP-Binding Cassette (ABC) transporters has known to be one of the major obstacles impeding the success of chemotherapy... 
Voruciclib | ATP-binding cassette transporters | ABCB1 | Multidrug resistance | ABCG2 | PHYSIOLOGY | TRANSPORTER | VIVO | SPECIFICITY | MEDIATED DRUG-RESISTANCE | MODULATORS | CELL BIOLOGY | TYROSINE KINASE INHIBITORS | BREAST-CANCER | IN-VITRO | REVERSAL AGENTS | Cyclin-Dependent Kinase 6 - antagonists & inhibitors | Paclitaxel - pharmacology | ATP Binding Cassette Transporter, Subfamily G, Member 2 - metabolism | Apoptosis - drug effects | Humans | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Benzopyrans - chemistry | Protein Kinase Inhibitors - chemistry | HEK293 Cells | ATP Binding Cassette Transporter, Subfamily B - genetics | Antineoplastic Agents - pharmacology | Benzopyrans - pharmacology | Cyclin-Dependent Kinase 4 - antagonists & inhibitors | Neoplasm Proteins - genetics | ATP Binding Cassette Transporter, Subfamily G, Member 2 - antagonists & inhibitors | Binding Sites | Protein Structure, Tertiary | Cell Survival - drug effects | ATP Binding Cassette Transporter, Subfamily G, Member 2 - genetics | Cyclin-Dependent Kinase 6 - metabolism | Imino Furanoses - pharmacology | Antineoplastic Agents - chemistry | Cyclin-Dependent Kinase 4 - metabolism | ATP Binding Cassette Transporter, Subfamily B - metabolism | ATP Binding Cassette Transporter, Subfamily B - antagonists & inhibitors | Imino Furanoses - chemistry | Cell Line, Tumor | Mitoxantrone - pharmacology | Molecular Docking Simulation | Protein Kinase Inhibitors - pharmacology | Mutation | Multidrug Resistance-Associated Proteins - metabolism | Doxorubicin - pharmacology | Drug Resistance, Neoplasm - drug effects | Cytotoxicity | Breast cancer | Kinases | Drug resistance | Cancer therapies | Penicillin
Journal Article
Current Medicinal Chemistry, ISSN 0929-8673, 07/2006, Volume 13, Issue 16, pp. 1859 - 1876
Journal Article
Molecular Carcinogenesis, ISSN 0899-1987, 08/2014, Volume 53, Issue 8, pp. 625 - 634
A major challenge of successful chemotherapy in ovarian cancer is overcoming intrinsic or acquired multi‐drug resistance caused by active drug efflux mediated... 
ABCB1 | hedgehog | Gli1 | ovarian cancer | ABCG2 | Hedgehog | Ovarian cancer | CELLS | ACTIVATION | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | STEM | SPHEROIDS | ONCOLOGY | PATHWAY | GROWTH | MULTIDRUG-RESISTANCE | EXPRESSION | Luciferases - metabolism | Apoptosis - drug effects | Drug Resistance, Multiple | Humans | Ovarian Neoplasms - pathology | Hedgehog Proteins - metabolism | Neoplasms, Glandular and Epithelial - metabolism | Drug Resistance, Neoplasm | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Immunoenzyme Techniques | ATP-Binding Cassette Transporters - genetics | Hedgehog Proteins - genetics | ATP-Binding Cassette Transporters - metabolism | Female | Antineoplastic Agents - pharmacology | Electrophoretic Mobility Shift Assay | Ovarian Neoplasms - metabolism | Tumor Cells, Cultured | Neoplasm Proteins - genetics | Ovarian Neoplasms - drug therapy | Real-Time Polymerase Chain Reaction | ATP Binding Cassette Transporter, Subfamily G, Member 2 | Neoplasms, Glandular and Epithelial - pathology | RNA, Messenger - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | ATP Binding Cassette Transporter, Subfamily B | ATP Binding Cassette Transporter, Subfamily B, Member 1 - genetics | ATP Binding Cassette Transporter, Subfamily B, Member 1 - antagonists & inhibitors | ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism | Neoplasms, Glandular and Epithelial - drug therapy | Carcinoma, Ovarian Epithelial | Cell Proliferation - drug effects | ATP-Binding Cassette Transporters - antagonists & inhibitors | Prevention