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Biochemical Pharmacology, ISSN 0006-2952, 2009, Volume 78, Issue 2, pp. 153 - 161
Journal Article
Cancer Research, ISSN 0008-5472, 10/2010, Volume 70, Issue 20, pp. 7981 - 7991
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 02/2013, Volume 41, Issue 2, pp. 353 - 361
Dolutegravir (DTG; S/GSK1349572) is a potent HIV-1 integrase inhibitor with a distinct resistance profile and a once-daily dose regimen that does not require... 
SERUM CREATININE LEVELS | IMMUNODEFICIENCY-VIRUS-INFECTION | HUMAN HEPATOCYTES | HEALTHY-SUBJECTS | CYTOCHROME-P450 ENZYMES | GLOMERULAR-FILTRATION | PHARMACOLOGY & PHARMACY | GASTROINTESTINAL PH | MULTIDRUG-RESISTANCE | BOOSTED PROTEASE INHIBITORS | P-GLYCOPROTEIN | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | HIV Integrase Inhibitors - pharmacology | Heterocyclic Compounds, 3-Ring - metabolism | Cricetulus | Cytochrome P-450 Enzyme Inhibitors | Heterocyclic Compounds, 3-Ring - pharmacology | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Cytochrome P-450 Enzyme System - metabolism | Membrane Transport Proteins - drug effects | Male | Neoplasm Proteins - antagonists & inhibitors | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Neoplasm Proteins - metabolism | Organic Anion Transporters - metabolism | Glucuronosyltransferase - genetics | Drug Interactions | Transfection | Membrane Transport Proteins - genetics | Microsomes, Liver - drug effects | Madin Darby Canine Kidney Cells | ATP-Binding Cassette Transporters - metabolism | Female | Membrane Transport Proteins - metabolism | Microsomes, Liver - enzymology | Hepatocytes - drug effects | CHO Cells | Cricetinae | Organic Anion Transporters - antagonists & inhibitors | Isoenzymes | Enzyme Induction | HIV Integrase Inhibitors - metabolism | Multidrug Resistance-Associated Proteins - antagonists & inhibitors | Animals | Glucuronosyltransferase - metabolism | Dogs | Cytochrome P-450 Enzyme System - genetics | Glucuronosyltransferase - antagonists & inhibitors | ATP Binding Cassette Transporter, Sub-Family B | Multidrug Resistance-Associated Proteins - metabolism | ATP-Binding Cassette Transporters - antagonists & inhibitors | Hepatocytes - enzymology
Journal Article
Journal Article