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1. Opioid transport by ATP-binding cassette transporters at the blood-brain barrier: Implications for neuropsychopharmacology
by Tournier, Nicolas and Declèves, Xavier and Saubaméa, Bruno and Scherrmann, Jean-Michel and Cisternino, Salvatore
Current Pharmaceutical Design, ISSN 1381-6128, 2011, Volume 17, Issue 26, pp. 2829 - 2842
Some of the ATP-binding cassette (ABC) transporters like P-glycoprotein (P-gp; ABCB1, MDR1), BCRP (ABCG2) and MRPs (ABCCs) that are present at the blood-brain... 
P-glycoprotein | Addiction | Blood-brain barrier | Opioids | SLC transporters | Tolerance | Morphine | ABC transporters | Drugs of abuse | MULTIDRUG TRANSPORTER | MORPHINE TRANSPORT | DRUG-INTERACTIONS | addiction | HUMAN LIVER-MICROSOMES | P-GLYCOPROTEIN ABCB1 | morphine | drugs of abuse | INTESTINAL-ABSORPTION | EFFLUX TRANSPORTERS | IN-VIVO | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | tolerance | opioids | CANCER RESISTANCE PROTEIN | Animals | Central Nervous System - metabolism | Biological Transport | Cytokines - metabolism | Humans | Analgesics, Opioid - pharmacokinetics | Neurotransmitter Agents - metabolism | ATP-Binding Cassette Transporters - metabolism | Analgesics, Opioid - pharmacology | Central Nervous System - drug effects | Blood-Brain Barrier - metabolism
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2. Full Text Endocrine Disruptors Differentially Target ATP-Binding Cassette Transporters in the Blood-Testis Barrier and Affect Leydig Cell Testosterone Secretion In Vitro
by Dankers, A.C.A and Roelofs, M.J and Piersma, A.H and Sweep, C.G.J and Russel, F.G.M and Berg, M. van den and Duursen, M.B. van and Masereeuw, R
Toxicological Sciences, ISSN 1096-6080, 2013, Volume 136, Issue 2, pp. 382 - 391
Endocrine-disrupting chemicals (EDCs) are considered to cause testicular toxicity primarily via interference with steroid hormone function. Alternatively, EDCs... 
Endocrine disrupting chemicals (EDCs) | ABC transporters | Steroidogenesis | Blood-testis barrier | MA-10 mouse Leydig cells | steroidogenesis | TETRABROMOBISPHENOL-A | RATS | IDENTIFICATION | P-GLYCOPROTEIN | endocrine disrupting chemicals (EDCs) | INHIBITION | EFFLUX | blood-testis barrier | BROMINATED FLAME RETARDANTS | BISPHENOL-A | TOXICOLOGY | EXPRESSION | XENOGRAFTS | Testosterone - secretion | Humans | Cells, Cultured | Male | Leydig Cells - drug effects | Endocrine Disruptors - toxicity | Leydig Cells - secretion | Animals | Dogs | HEK293 Cells | ATP-Binding Cassette Transporters - metabolism | Blood-Testis Barrier - drug effects | Mice | Index Medicus
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3. Full Text Novel Formulation of a Reconstituted High-Density Lipoprotein (CSL112) Dramatically Enhances ABCA1-Dependent Cholesterol Efflux
by Diditchenko, Svetlana and Gille, Andreas and Pragst, Ingo and Stadler, Dominik and Waelchli, Marcel and Hamilton, Ross and Leis, Andrew and Wright, Samuel D
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 09/2013, Volume 33, Issue 9, pp. 2202 - 2211
OBJECTIVE—The ability of high-density lipoprotein (HDL) to remove cholesterol from atherosclerotic plaque is thought to underlie its inverse correlation with... 
high-density lipoproteins, pre-ß | cholesterol | apolipoproteins | acute coronary syndrome | inflammation | REGRESSION | LECITHINCHOLESTEROL ACYLTRANSFERASE | CELLULAR CHOLESTEROL | HUMAN ATHEROSCLEROTIC PLAQUE | high-density lipoproteins, pre-beta | INTRAVENOUS-INFUSION | TRANSPORT | PERIPHERAL VASCULAR DISEASE | MICE | HEMATOLOGY | A-I | LECITHIN | Apolipoprotein A-I - pharmacology | Lipoproteins, HDL - pharmacokinetics | Up-Regulation | Anticholesteremic Agents - blood | Lipoproteins, HDL - blood | Cholesterol - blood | Humans | Cholesterol Esters - blood | Apolipoprotein A-I - pharmacokinetics | Lipoproteins, HDL - pharmacology | Biological Transport | Female | ATP Binding Cassette Transporter 1 | Macrophages - immunology | Cytokines - blood | Cell Line | Lipoproteins, HDL - administration & dosage | Rabbits | Anti-Inflammatory Agents - pharmacology | Inflammation Mediators - blood | Particle Size | Anticholesteremic Agents - pharmacokinetics | Macrophages - metabolism | Animals | ATP-Binding Cassette Transporters - drug effects | Anticholesteremic Agents - administration & dosage | ATP-Binding Cassette Transporters - blood | Cholesterol, HDL - blood | Macrophages - drug effects | Apolipoprotein A-I - administration & dosage | Mice | Infusions, Intravenous | Anticholesteremic Agents - pharmacology | Apolipoprotein A-I - blood
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4. Full Text Characterization of the Humoral Immune Response during Staphylococcus aureus Bacteremia and Global Gene Expression by Staphylococcus aureus in Human Blood
by Reijer, Martijn and Lemmens-den Toom, Nicole and Kant, Samantha and Snijders, Susan and Boelens, Hélène and Tavakol, Mehri and Verkaik, Nelianne and Belkum, Alex and Verbrugh, Henri and Wamel, Willem
PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, p. e53391
textabstractAttempts to develop an efficient anti-staphylococcal vaccine in humans have so far been unsuccessful. Therefore, more knowledge of the antigens... 
HETEROGENEITY | METHICILLIN RESISTANCE | GAMMA-HEMOLYSIN | RISK-FACTORS | PROTEIN | LEUKOCIDIN | SUPERANTIGENS | MULTIDISCIPLINARY SCIENCES | STREAM INFECTIONS | ENDOCARDITIS | ANTIBODY-RESPONSES | Bacteremia - immunology | Immunoglobulin G - blood | Humans | Middle Aged | Antigens, Bacterial - immunology | Male | Gene Expression Profiling | Antigens, Bacterial - blood | Phylogeny | Bacteremia - microbiology | ATP-Binding Cassette Transporters - genetics | Immunity, Humoral | Immunoglobulin G - immunology | Bacteremia - blood | Female | Bacterial Proteins - immunology | Staphylococcal Infections - microbiology | Antibodies, Bacterial - blood | Genome, Bacterial - immunology | Staphylococcal Infections - blood | Staphylococcus aureus - genetics | Gene Expression | Staphylococcal Infections - immunology | Staphylococcus aureus - isolation & purification | Bacterial Proteins - genetics | Bacterial Proteins - blood | Staphylococcus aureus - classification | Immunoglobulin A - immunology | ATP-Binding Cassette Transporters - blood | Immunoglobulin A - blood | Antibodies, Bacterial - immunology | Staphylococcus aureus - immunology | Aged | ATP-Binding Cassette Transporters - immunology | Antigens | Medical research | Analysis | Genes | Immunoglobulin G | Medicine, Experimental | Genetic aspects | Vaccines | Bacterial genetics | Gene expression | Bacteremia | Staphylococcus aureus | Flow cytometry | Virulence | Antibodies | Iron | Immunoglobulin A | Blood | Proteins | Virulence factors | Immune system | Immune response | Incubation | Staphylococcus infections | Patients | Immune response (humoral) | Studies | Cytometry | Infectious diseases | DNA microarrays | Immunogenicity | Proteomics | Transporter | ABC transporter
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5. Full Text ATP Binding Cassette Subfamily A Member 2 (ABCA2) Expression and Methylation are Associated with Alzheimer's Disease
by Hu, WH and Lin, XD and Zhang, HH and Zhao, N
MEDICAL SCIENCE MONITOR, ISSN 1643-3750, 12/2017, Volume 23, pp. 5851 - 5861
Background: ABCA2 has been genetically linked to Alzheimer's disease (AD) risk, but its mRNA expression and epigenetics in AD have not been investigated.... 
MEDICINE, RESEARCH & EXPERIMENTAL | TRIALS | HUMAN BRAIN | CHOLESTEROL | TRANSPORTERS | TISSUE | Gene Expression Profiling | Alzheimer Disease | BIOMARKERS | ATP-Binding Cassette Transporters | EFFLUX | GENE | NEUROPATHOLOGY | Methylation | Up-Regulation | Genetic Predisposition to Disease | Cognitive Dysfunction - metabolism | Epigenesis, Genetic | Humans | RNA, Messenger - genetics | Databases, Genetic | Huntington Disease - metabolism | Tissue Array Analysis - methods | ATP-Binding Cassette Transporters - biosynthesis | Alzheimer Disease - diagnosis | RNA, Messenger - biosynthesis | Amyloid beta-Protein Precursor - genetics | RNA, Messenger - blood | ATP-Binding Cassette Transporters - genetics | ATP-Binding Cassette Transporters - blood | Alzheimer Disease - metabolism | ATP-Binding Cassette Transporters - metabolism | CpG Islands | Huntington Disease - genetics | Cognitive Dysfunction - genetics | Alzheimer Disease - genetics | Alzheimer Disease - blood
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6. Full Text The ABCG5/8 Cholesterol Transporter and Myocardial Infarction Versus Gallstone Disease
by Stender, Stefan, MD, PhD and Frikke-Schmidt, Ruth, MD, DMSc and Nordestgaard, Børge G., MD, DMSc and Tybjærg-Hansen, Anne, MD, DMSc
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2014, Volume 63, Issue 20, pp. 2121 - 2128
Objectives The study sought to test the hypothesis that genetic variation in ABCG5/8 , the transporter responsible for intestinal and hepatobiliary cholesterol... 
Cardiovascular | Internal Medicine | ABCG8 | cholesterol | myocardial infarction | ABCG5 | gallstones | myocardial infarction | CARDIAC & CARDIOVASCULAR SYSTEMS | MENDELIAN RANDOMIZATION | HYPERCHOLESTEROLEMIA | POLYMORPHISM | DENSITY-LIPOPROTEIN CHOLESTEROL | CAUSAL RISK-FACTOR | CARDIOVASCULAR-DISEASE | MICE | ABSORPTION | SECRETION | ASSOCIATION | Myocardial Infarction - blood | Myocardial Infarction - genetics | Myocardial Infarction - epidemiology | Prevalence | Lipoproteins - genetics | Humans | Middle Aged | Gallstones - epidemiology | Genotype | Male | Lipoproteins - blood | Gallstones - blood | Genetic Variation | Gallstones - genetics | ATP-Binding Cassette Transporters - genetics | ATP-Binding Cassette Transporters - blood | Denmark - epidemiology | Female | ATP Binding Cassette Transporter, Sub-Family G, Member 8 | Aged | ATP Binding Cassette Transporter, Sub-Family G, Member 5 | Gallstones | Sects | Analysis | Cholesterol | Heart attack | Low density lipoproteins | Risk factors | Hormone replacement therapy | Heart attacks | Low density lipoprotein
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7. Full Text Deficiency of Brain ATP-Binding Cassette Transporter A-1 Exacerbates Blood–Brain Barrier and White Matter Damage After Stroke
by Cui, Xu and Chopp, Michael and Zacharek, Alex and Karasinska, Joanna M and Cui, Yisheng and Ning, Ruizhuo and Zhang, Yi and Wang, Yun and Chen, Jieli
Stroke, ISSN 0039-2499, 03/2015, Volume 46, Issue 3, pp. 827 - 834
BACKGROUND AND PURPOSE—The ATP-binding cassette transporter A-1 (ABCA1) gene is a key target of the transcription factors liver X receptors. Liver X receptor... 
Aquaporin 4 | Stroke | Insulin-like growth factor binding protein 1 | Blood-brain barrier | White matter | ATP binding cassette transporter A-1 | blood-brain barrier | ABCA1 | SYSTEM | INJURY | stroke | CLINICAL NEUROLOGY | white matter | insulin-like growth factor binding protein 1 | NEUROINFLAMMATION | INTEGRITY | aquaporin 4 | DISEASE | AQUAPORIN-4 | PERIPHERAL VASCULAR DISEASE | CEREBRAL-ISCHEMIA | EXPRESSION | PERICYTES | Astrocytes - cytology | Immunohistochemistry | Cells, Cultured | Male | Mice, Transgenic | Treatment Outcome | Infarction, Middle Cerebral Artery - pathology | Stroke - genetics | Mice, Knockout | White Matter - pathology | Stroke - blood | Blood-Brain Barrier - pathology | Matrix Metalloproteinase 9 - metabolism | Animals | ATP Binding Cassette Transporter 1 - physiology | Mice | Brain Injuries - pathology | Insulin-Like Growth Factor I - metabolism | ATP Binding Cassette Transporter 1 - genetics | Disease Models, Animal
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8. Full Text N-desmethyl-loperamide is selective for P-glycoprotein among three ATP-binding cassette transporters at the blood-brain barrier
by Kannan, Pavitra and Brimacombe, Kyle R and Zoghbi, Sami S and Liow, Jeih-San and Morse, Cheryl and Taku, Andrew K and Pike, Victor W and Halldin, Christer and Innis, Robert B and Gottesman, Michael M and Hall, Matthew D
Drug Metabolism and Disposition, ISSN 0090-9556, 06/2010, Volume 38, Issue 6, pp. 917 - 922
[C-11] N-desmethyl-Loperamide ([C-11]dLop) is used in positron emission tomography (PET) to measure the in vivo activity of efflux transporters that block the... 
CELLS | INHIBITION | DISEASES | SUBSTRATE | PHARMACOLOGY & PHARMACY | MULTIDRUG-RESISTANCE | CANCER | TARIQUIDAR | XR9576 | DRUG EFFLUX TRANSPORTERS | REVERSAL | Tissue Distribution - physiology | Radiopharmaceuticals - pharmacokinetics | Humans | Glycoproteins - metabolism | Loperamide - pharmacology | Cerebrovascular Circulation | Loperamide - analogs & derivatives | Blood-Brain Barrier - metabolism | Brain - metabolism | Anti-HIV Agents - chemistry | ATP Binding Cassette Transporter, Subfamily B, Member 1 | Animals | Loperamide - pharmacokinetics | Anti-HIV Agents - pharmacokinetics | ATP-Binding Cassette Transporters - metabolism | Biological Transport - physiology | Mice | Tumor Cells, Cultured | Loperamide - chemistry | Multidrug Resistance-Associated Proteins
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9. Full Text ABCG2 functions as a general phytoestrogen sulfate transporter in vivo
by Van De Wetering, Koen and Sapthu, Sunny
FASEB Journal, ISSN 0892-6638, 10/2012, Volume 26, Issue 10, pp. 4014 - 4024
ABCG2 is an ATP-dependent efflux transporter that limits the systemic exposure of its substrates. The preferred substrates of ABCG2 in vivo are largely... 
BCRP | Metabolomics | Phase II metabolism | Vesicular transport | GLUCURONIDE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENISTEIN | EXCRETION | DISPOSITION | phase II metabolism | CELL BIOLOGY | METABOLISM | ACETAMINOPHEN | metabolomics | BIOLOGY | INFERTILITY | EXPRESSION | vesicular transport | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Membrane Transport Proteins - blood | Male | Membrane Transport Proteins - urine | Chromatography, High Pressure Liquid | Mice, Knockout | Animals | ATP-Binding Cassette Transporters - genetics | Membrane Transport Proteins - genetics | Mass Spectrometry | ATP-Binding Cassette Transporters - blood | ATP-Binding Cassette Transporters - metabolism | Female | Membrane Transport Proteins - metabolism | Phytoestrogens - metabolism | Biological Transport - genetics | Biological Transport - physiology | Mice | ATP-Binding Cassette Transporters - urine
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10. Full Text Methotrexate Withdrawal at 6 vs 12 Months in Juvenile Idiopathic Arthritis in Remission: A Randomized Clinical Trial
by Foell, Dirk and Wulffraat, Nico and Wedderburn, Lucy R and Wittkowski, Helmut and Frosch, Michael and Gerß, Joachim and Stanevicha, Valda and Mihaylova, Dimitrina and Ferriani, Virginia and Tsakalidou, Florence Kanakoudi and Foeldvari, Ivan and Cuttica, Ruben and Gonzalez, Benito and Ravelli, Angelo and Khubchandani, Raju and Oliveira, Sheila and Armbrust, Wineke and Garay, Stella and Vojinovic, Jelena and Norambuena, Ximena and Gamir, María Luz and García-Consuegra, Julia and Lepore, Loredana and Susic, Gordana and Corona, Fabrizia and Dolezalova, Pavla and Pistorio, Angela and Martini, Alberto and Ruperto, Nicolino and Roth, Johannes and Paediatric Rheumatology International Trials Organization (PRINTO), for the and PRINTO and Paediatric Rheumatology International Trials Organization (PRINTO)
JAMA, ISSN 0098-7484, 04/2010, Volume 303, Issue 13, pp. 1266 - 1273
CONTEXT Novel therapies have improved the remission rate in chronic inflammatory disorders including juvenile idiopathic arthritis (JIA). Therefore, strategies... 
RHEUMATOID-ARTHRITIS | CRITERIA | THERAPY | PROTEINS 8 | INFLAMMATION | VALIDATION | SELECT CATEGORIES | UMCG Approved | DISCONTINUATION | DISEASE-ACTIVITY | CHILDREN | MEDICINE, GENERAL & INTERNAL | Predictive Value of Tests | Recurrence | Calgranulin B - blood | Prospective Studies | Antirheumatic Agents - administration & dosage | Humans | Child, Preschool | Infant | Male | Remission Induction | Arthritis, Juvenile - drug therapy | ATP-Binding Cassette Transporters - blood | Adolescent | Female | Methotrexate - administration & dosage | Child | Clinical trials | Biomarkers | Patient safety | Arthritis | Drug therapy | Risk factors
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11. Full Text HDL Remodeling During the Acute Phase Response
by Jahangiri, Anisa and de Beer, Maria C and Noffsinger, Victoria and Tannock, Lisa R and Ramaiah, Chandrashekar and Webb, Nancy R and van der Westhuyzen, Deneys R and de Beer, Frederick C
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 02/2009, Volume 29, Issue 2, pp. 261 - 267
OBJECTIVE—The purpose of this study was to examine the interactive action of serum amyloid A (SAA), group IIA secretory phospholipase A2 (sPLA2-IIA), and... 
CETP | HDL | SAA | Inflammation | apoA-I | ESTER TRANSFER PROTEIN | SIZE | SERUM-AMYLOID-A | SECRETORY PHOSPHOLIPASE A | HIGH-DENSITY-LIPOPROTEIN | ANTIINFLAMMATORY PROPERTIES | PLASMA | MESSENGER-RNA | METABOLISM | inflammation | REVERSE CHOLESTEROL TRANSPORT | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Recombinant Proteins - metabolism | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Serum Amyloid A Protein - metabolism | Lipoproteins, HDL - blood | Cholesterol - blood | Humans | Cardiac Surgical Procedures - adverse effects | Group II Phospholipases A2 - blood | Cholesterol Ester Transfer Proteins - blood | Macrophages - metabolism | Chromatography, Affinity | Time Factors | ATP-Binding Cassette Transporters - blood | Acute-Phase Reaction - blood | ATP Binding Cassette Transporter 1 | Acute-Phase Reaction - etiology | Apolipoprotein A-I - blood
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12. Full Text Chlorogenic acid protects against atherosclerosis in ApoE-/-mice and promotes cholesterol efflux from RAW264.7 macrophages
by Wu, Chongming and Luan, Hong and Zhang, Xue and Wang, Shuai and Zhang, Xiaopo and Sun, Xiaobo and Guo, Peng
PLoS ONE, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, pp. e95452 - e95452
Chlorogenic acid (CGA) is one of the most abundant polyphenols in the human diet and is suggested to be a potential antiatherosclerotic agent due to its... 
ACTIVATION | FOAM CELL-FORMATION | CAFFEIC ACID | PATHWAY | GLUCOSE | MULTIDISCIPLINARY SCIENCES | CARDIOVASCULAR-DISEASE | GENE-EXPRESSION | RATS | COFFEE CONSUMPTION | RECEPTOR-ALPHA | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Apolipoproteins E - deficiency | Atorvastatin Calcium - pharmacology | Chlorogenic Acid - pharmacology | Lipoproteins - genetics | Cholesterol - blood | Diet, High-Fat - adverse effects | Atherosclerosis - etiology | Caffeic Acids - isolation & purification | ATP-Binding Cassette Transporters - genetics | Liver X Receptors | Cholesterol, LDL - blood | Biological Transport - drug effects | Plaque, Atherosclerotic - blood | Plaque, Atherosclerotic - pathology | PPAR gamma - genetics | Gallic Acid - isolation & purification | Cell Line | Atherosclerosis - pathology | Gene Expression | Atherosclerosis - drug therapy | Macrophages - pathology | Aorta - drug effects | ATP Binding Cassette Transporter 1 - blood | Lipoproteins - blood | Orphan Nuclear Receptors - genetics | Mice, Knockout | Plaque, Atherosclerotic - etiology | Atherosclerosis - blood | Orphan Nuclear Receptors - blood | Macrophages - metabolism | Animals | Lipoproteins, LDL - antagonists & inhibitors | Apolipoproteins E - genetics | Coumaric Acids - isolation & purification | ATP-Binding Cassette Transporters - blood | Triglycerides - blood | Macrophages - drug effects | Mice | Plaque, Atherosclerotic - drug therapy | Vasodilation - drug effects | Chlorogenic Acid - chemistry | PPAR gamma - blood | Anticholesteremic Agents - pharmacology | Cholesterol - adverse effects | Lipoproteins, LDL - blood | ATP Binding Cassette Transporter 1 - genetics | Oxidative stress | Transcription | Glucose | Macrophages | Coffee | ABCA1 protein | Toxicology | Ultrasonic imaging | Metabolites | Apolipoprotein E | Rodents | Atherosclerosis | Polyphenols | Aorta | Supplementation | Stretching | Food | Efflux | Dietary supplements | Chlorogenic acid | Triglycerides | Pharmacology | Inflammation | Gene expression | Cholesterol | Herbal medicine | Acids | Diet | Arteriosclerosis | Coronary vessels | Atorvastatin | ATP-binding protein | Plasma levels | Laboratory animals | Index Medicus
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13. Full Text MRP8/14 serum levels as a strong predictor of response to biological treatments in patients with rheumatoid arthritis
by Choi, Ivy Y and Gerlag, Danielle M and Herenius, Marieke J and Thurlings, Rogier M and Wijbrandts, Carla A and Foell, Dirk and Vogl, Thomas and Roth, Johannes and Tak, Paul P and Holzinger, Dirk
Annals of the rheumatic diseases, ISSN 0003-4967, 2015, Volume 74, Issue 3, pp. 499 - 505
Background One-third of rheumatoid arthritis (RA) patients treated with biological therapy show lack of response. The use of predictive biomarkers to identify... 
C-REACTIVE PROTEIN | BIOMARKERS | SYNOVIAL TISSUE | RITUXIMAB | JUVENILE IDIOPATHIC ARTHRITIS | RECEPTOR | MONOCLONAL-ANTIBODY | RHEUMATOLOGY | ANTITUMOR NECROSIS FACTOR | S100 PROTEINS | DISEASE-ACTIVITY | Antibodies, Monoclonal, Humanized - therapeutic use | Calgranulin B - blood | Prognosis | Prospective Studies | Arthritis, Rheumatoid - blood | Humans | Middle Aged | Rituximab | Antibodies, Monoclonal - therapeutic use | Male | Treatment Outcome | Biomarkers - blood | Infliximab | Arthritis, Rheumatoid - drug therapy | ATP-Binding Cassette Transporters - blood | Adult | Female | Adalimumab | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Antibodies, Monoclonal, Murine-Derived - therapeutic use | Antirheumatic Agents - therapeutic use | Cohort Studies | Care and treatment | Usage | Biological products | Rheumatoid arthritis | Analysis | Serum | Risk factors
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14. Full Text Metabolic syndrome, alcohol consumption and genetic factors are associated with serum uric acid concentration
by Stibůrková, Blanka and Pavlíková, Markéta and Sokolová, Jitka and Kožich, Viktor
PLoS ONE, ISSN 1932-6203, 05/2014, Volume 9, Issue 5, p. e97646
Objective: Uric acid is the end product of purine metabolism in humans, and increased serum uric acid concentrations lead to gout. The objective of the current... 
METHYLENETETRAHYDROFOLATE REDUCTASE | SLC2A9 | RENAL HYPOURICEMIA | ABCG2 GENE | RISK-FACTORS | HYPERURICEMIA | GOUT | MULTIDISCIPLINARY SCIENCES | TETRAHYDROFOLATE REDUCTASE GENE | POLYMORPHISM | URATE TRANSPORTER | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Glucose Transport Proteins, Facilitative - blood | Humans | Middle Aged | Male | Metabolic Syndrome - blood | ATP-Binding Cassette Transporters - genetics | Methylenetetrahydrofolate Reductase (NADPH2) - genetics | Methylenetetrahydrofolate Reductase (NADPH2) - blood | Adult | Female | Uric Acid - blood | Glucose Transport Proteins, Facilitative - genetics | Neoplasm Proteins - genetics | Gene Expression | Alcohol Drinking - pathology | Alcohol Drinking - genetics | Regression Analysis | Alcohol Drinking - blood | Metabolic Syndrome - genetics | ATP-Binding Cassette Transporters - blood | Adolescent | Sex Factors | Neoplasm Proteins - blood | Aged | Models, Genetic | Polymorphism, Single Nucleotide | Metabolic Syndrome - pathology | Cohort Studies | Genetic research | Physiological aspects | Genetic aspects | Drinking of alcoholic beverages | Uric acid | Wine | Disease | Control methods | Anthropometry | Genes | Gout | Alcohol | Genomes | Arthritis | Methylenetetrahydrofolate reductase | Criteria | Metabolic syndrome | Alcohols | Demographic variables | Body mass index | Demographics | Regression models | Rheumatism | ABCG gene | Genetic factors | Hypertension | Enzymes | Adenosine | Drinking behavior | Regression analysis | Metabolism | Medicine | Studies | Genetic variance | Hospitals | Acids | Mutation | Transporter | Metabolic disorders
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