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Drug Metabolism and Disposition, ISSN 0090-9556, 02/2009, Volume 37, Issue 2, pp. 359 - 365
Sunitinib malate (Sutent, SU11248) is a small-molecule receptor tyrosine kinase inhibitor that inhibits cellular signaling of multiple targets such as the... 
CHRONIC MYELOGENOUS LEUKEMIA | HIGH-AFFINITY INTERACTION | MULTIDRUG TRANSPORTER | MEDIATED DRUG EFFLUX | MRP1 ABCC1 | HEMATOPOIETIC STEM-CELLS | DIFFERENTIAL IMMUNOREACTIVITY | PHARMACOLOGY & PHARMACY | ANTITUMOR-ACTIVITY | IMATINIB MESYLATE | CANCER RESISTANCE PROTEIN | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Hydrolysis - drug effects | Humans | Protein Conformation - drug effects | Neoplasm Proteins - antagonists & inhibitors | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | ATP-Binding Cassette Transporters - chemistry | Adenosine Triphosphate - metabolism | ATP-Binding Cassette Transporters - metabolism | Indoles - pharmacology | ATP-Binding Cassette, Sub-Family B, Member 1 - chemistry | Biological Transport - drug effects | Photoaffinity Labels | Adenosine Triphosphatases - metabolism | Multidrug Resistance-Associated Proteins - antagonists & inhibitors | Neoplasm Proteins - chemistry | Pyrimidines - pharmacology | Imatinib Mesylate | Piperazines - pharmacology | Xenograft Model Antitumor Assays | Pyrroles - pharmacology | ATP-Binding Cassette Transporters - drug effects | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Benzamides | Antineoplastic Agents, Phytogenic - pharmacology | Cell Line, Transformed | ATP-Binding Cassette Transporters - antagonists & inhibitors | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, pp. e0134779 - e0134779
In ticks, the digestion of blood occurs intracellularly and proteolytic digestion of hemoglobin takes place in a dedicated type of lysosome, the digest... 
TRYPANOSOMA-CRUZI EPIMASTIGOTES | MULTIDISCIPLINARY SCIENCES | CATTLE | IVERMECTIN | RESISTANCE | ABC TRANSPORTERS | AEDES-AEGYPTI | PROTEINS | IDENTIFICATION | RHIPICEPHALUS BOOPHILUS MICROPLUS | P-GLYCOPROTEIN | Protein Structure, Tertiary | Rhodamine 123 - chemistry | Antibodies - chemistry | Toluidines - pharmacokinetics | Chromatography, High Pressure Liquid | Tick Infestations - drug therapy | Rhipicephalus - physiology | Arthropod Proteins - chemistry | ATP-Binding Cassette Transporters - chemistry | Acaricides - chemistry | Animals | Heme - chemistry | RNA Interference | Cattle | Cyclosporine - chemistry | Metalloporphyrins - chemistry | Protein Binding | Female | Protoporphyrins - chemistry | Adenosine Triphosphate - chemistry | Intestines - physiology | Metalloporphyrins - pharmacokinetics | Rhodamine 123 - pharmacokinetics | Toluidines - chemistry | Physiological aspects | Hemoglobin | Pesticide resistance | Chemical properties | Heme | Pesticides | Rhodamine | Membranes | Transcription | Toxicity | Cyclosporins | Midgut | Ticks | Biology | Fluorescent indicators | Drug resistance | Blood | Acaricides | Parasitic diseases | Proteolysis | ABC transporters | Arachnids | Binding | Enzymes | RNA-mediated interference | Detoxification | Digestion | Molecular chains | Substrates | ATP | Transporter | ABC transporter | Index Medicus
Journal Article
Journal Article