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Plant Physiology, ISSN 0032-0889, 7/2015, Volume 168, Issue 3, pp. 814 - 827
Arabidopsis ( ) ( ) genes quantitatively contribute to the execution of different forms of plant immunity upon challenge with diverse leaf pathogens. encodes a... 
ATP binding cassette transporters | Mildews | Pathogens | Leaves | Phenotypes | Inoculation | Alleles | Biosynthesis | Plants | BIOCHEMISTRY AND METABOLISM | Genotypes | NONHOST RESISTANCE | SECONDARY METABOLITES | ARABIDOPSIS-THALIANA | MEMBRANE ABC TRANSPORTER | SALICYLIC-ACID | PRECURSOR INDOLE-3-BUTYRIC ACID | ENDOPLASMIC-RETICULUM | DRUG-RESISTANCE TRANSPORTER | BASIPETAL AUXIN TRANSPORT | GLUCOSINOLATE METABOLISM | PLANT SCIENCES | Amino Acid Sequence | Arabidopsis - drug effects | Disease Susceptibility | Ascomycota - physiology | Pathogen-Associated Molecular Pattern Molecules - metabolism | Salicylic Acid - metabolism | Adaptation, Physiological - drug effects | Molecular Sequence Data | Plant Diseases - microbiology | Mutation - genetics | Tryptophan - metabolism | Arabidopsis - metabolism | Plant Roots - drug effects | Arabidopsis - microbiology | ATP-Binding Cassette Transporters - chemistry | ATP-Binding Cassette Transporters - genetics | Models, Biological | ATP-Binding Cassette Transporters - metabolism | Indoles - pharmacology | Metabolic Networks and Pathways - drug effects | Plant Roots - growth & development | Amino Acid Substitution | Allelomorphism | Gene mutations | Physiological aspects | Tryptophan | Identification and classification | Adenosine triphosphate | Protein binding | Index Medicus
Journal Article
Journal Article
Science, ISSN 0036-8075, 8/2004, Volume 305, Issue 5685, pp. 869 - 872
Journal Article
FASEB Journal, ISSN 0892-6638, 12/2007, Volume 21, Issue 14, pp. 3937 - 3948
The recently reported structures of the bacterial multidrug exporter Sav1866 suggest a domain architecture in which both nucleotide- binding domains ( NBDs) of... 
ABC protein | MDR1 | ABCB1 | Drug efflux | ATP binding cassette transporter | DRUG-BINDING | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | NUCLEOTIDE-BINDING DOMAIN | ATP-BINDING | CELL BIOLOGY | drug efflux | ABC-TRANSPORTER | BIOLOGY | RESISTANCE | TRANSMEMBRANE DOMAINS | CYSTIC-FIBROSIS | HEMOLYSIN-B | CATALYTIC CYCLE | Protein Binding - genetics | Humans | Bacterial Proteins - chemistry | Escherichia coli Proteins - physiology | ATP-Binding Cassette Transporters - physiology | Cysteine - genetics | Nucleotides - chemistry | ATP-Binding Cassette Transporters - chemistry | ATP-Binding Cassette Transporters - genetics | Membrane Proteins - physiology | Haemophilus influenzae - chemistry | ATP-Binding Cassette, Sub-Family B, Member 1 - chemistry | Cell Line | Mutagenesis, Site-Directed | Membrane Proteins - genetics | Bacterial Proteins - genetics | Haemophilus influenzae - genetics | Protein Structure, Tertiary - genetics | Bacterial Proteins - physiology | Nucleotides - metabolism | ATP-Binding Cassette, Sub-Family B, Member 1 - physiology | Membrane Proteins - chemistry | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Haemophilus influenzae - physiology | Escherichia coli Proteins - genetics | ATP Binding Cassette Transporter, Sub-Family B | Structural Homology, Protein | Drug Resistance, Multiple, Bacterial - genetics | Escherichia coli Proteins - chemistry | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2013, Volume 110, Issue 19, pp. 7696 - 7701
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2017, Volume 114, Issue 47, pp. 12572 - 12577
MacB is an ABC transporter that collaborates with the MacA adaptor protein and TolC exit duct to drive efflux of antibiotics and enterotoxin STII out of the... 
X-ray crystallography | ABC transporter | Tripartite efflux pump | HEAT-STABLE ENTEROTOXIN | EFFLUX TRANSPORTER | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | HYDROLYSIS | ATP-BINDING | MEMBRANE-FUSION PROTEIN | TOLC | tripartite efflux pump | MACROLIDE TRANSPORTER | MULTIDRUG EFFLUX | INHIBITORS | Protein Multimerization | Aggregatibacter actinomycetemcomitans - metabolism | Substrate Specificity | Crystallography, X-Ray | Cell Cycle Proteins - chemistry | ATP-Binding Cassette Transporters - chemistry | ATP-Binding Cassette Transporters - genetics | Biological Transport | Adenosine Triphosphate - metabolism | Escherichia coli - metabolism | ATP-Binding Cassette Transporters - metabolism | Cell Cycle Proteins - genetics | Protein Interaction Domains and Motifs | Binding Sites | Bacterial Outer Membrane Proteins - genetics | Recombinant Proteins - metabolism | Protein Conformation, alpha-Helical | Gene Expression | Cell Cycle Proteins - metabolism | Bacterial Outer Membrane Proteins - chemistry | Models, Molecular | Recombinant Proteins - chemistry | Escherichia coli Proteins - metabolism | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Recombinant Proteins - genetics | Cystic Fibrosis Transmembrane Conductance Regulator - chemistry | Bacterial Outer Membrane Proteins - metabolism | Protein Conformation, beta-Strand | Escherichia coli - genetics | Aggregatibacter actinomycetemcomitans - genetics | Escherichia coli Proteins - genetics | Protein Binding | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Adenosine Triphosphate - chemistry | Escherichia coli Proteins - chemistry | Research | Carrier proteins | Structure | Crystals | Efflux | Trafficking | Cell division | Homology | Crystallography | Substrates | Coupling (molecular) | Bellows | Signaling | Cellular biology | Antibiotics | Bacteria | ABC transporters | Dimerization | Transporter | ATP | Cytoplasm | Adenosine triphosphate | Index Medicus | Biological Sciences
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 09/2016, Volume 60, Issue 9, pp. 5400 - 5411
Nosocomial infections with Enterococcus faecalis are an emerging health problem. However, drug efflux pumps contributing to intrinsic drug resistance are... 
BINDING CASSETTE TRANSPORTER | TRANSITION | ATP HYDROLYSIS | STREPTOCOCCUS-PNEUMONIAE | STRUCTURAL BASIS | FLEXIBILITY | RESISTANCE | SITES | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | HIGH-THROUGHPUT CLONING | LACTOCOCCUS-LACTIS | Fluoroquinolones - chemistry | Sequence Deletion | Ethidium - chemistry | Protein Multimerization | Proteolipids - metabolism | Bacterial Proteins - chemistry | Ethidium - metabolism | Lactococcus lactis - metabolism | Doxorubicin - chemistry | Genetic Loci | Benzimidazoles - chemistry | ATP-Binding Cassette Transporters - chemistry | Chromosomes, Bacterial - metabolism | Fluoroquinolones - metabolism | ATP-Binding Cassette Transporters - genetics | Biological Transport | Adenosine Triphosphate - metabolism | Anti-Bacterial Agents - chemistry | Base Sequence | ATP-Binding Cassette Transporters - metabolism | Doxorubicin - metabolism | Protein Interaction Domains and Motifs | Daunorubicin - metabolism | Transgenes | Lactococcus lactis - genetics | Recombinant Proteins - metabolism | Amino Acid Sequence | Protein Conformation, alpha-Helical | Gene Expression | Chromosomes, Bacterial - chemistry | Enterococcus faecalis - genetics | Bacterial Proteins - genetics | Recombinant Proteins - chemistry | Anti-Bacterial Agents - metabolism | Recombinant Proteins - genetics | Daunorubicin - chemistry | Enterococcus faecalis - metabolism | Protein Conformation, beta-Strand | Benzimidazoles - metabolism | Protein Binding | Bacterial Proteins - metabolism | Adenosine Triphosphate - chemistry | Proteolipids - chemistry | Index Medicus
Journal Article
Cancer Letters, ISSN 0304-3835, 2012, Volume 328, Issue 2, pp. 307 - 317
Highlights ► Nilotinib compared to panel of tyrosine kinase inhibitors most potently reverse ABCB1, ABCG2 and ABCC10 transporters mediated drug resistance. ►... 
Hematology, Oncology and Palliative Medicine | Nilotinib | ABCB1/P-gp | ABC transporters | ABCG2/BCRP | Multidrug resistance | ABCC10/MRP7 | CANCER-CELLS | TRANSPORTERS | BCR-ABL | SUBFAMILY-B MEMBER-1 | TYROSINE KINASE INHIBITORS | IN-VITRO | PROTEIN BCRP/ABCG2 | ONCOLOGY | IMATINIB | REVERSES MULTIDRUG-RESISTANCE | BINDING | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Humans | Male | Antineoplastic Agents - administration & dosage | ATP-Binding Cassette Transporters - chemistry | ATP-Binding Cassette Transporters - genetics | Neoplasms - genetics | HEK293 Cells | Multidrug Resistance-Associated Proteins - genetics | Tumor Burden - genetics | ATP-Binding Cassette, Sub-Family B, Member 1 - chemistry | Antineoplastic Agents - pharmacology | Neoplasm Proteins - genetics | Pyrimidines - administration & dosage | Multidrug Resistance-Associated Proteins - chemistry | Neoplasm Proteins - chemistry | Pyrimidines - pharmacology | Neoplasms - drug therapy | Drug Synergism | Xenograft Model Antitumor Assays | Protein Kinase Inhibitors - administration & dosage | Drug Resistance, Neoplasm - genetics | Animals | Tumor Burden - drug effects | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Mice, Nude | Cell Line, Tumor | Protein Conformation | ATP Binding Cassette Transporter, Sub-Family B | Mice | Molecular Docking Simulation | Protein Kinase Inhibitors - pharmacology | Neoplasms - pathology | Tyrosine | Drug resistance in microorganisms | Anthracyclines | Care and treatment | Epidermal growth factor | Analysis | Universities and colleges | Cancer | Laboratories | Cytotoxicity | Bioavailability | Kinases | Metabolism | Drug resistance | DNA repair | Proteins | Studies | Chemotherapy | Metabolites | Tumors | Index Medicus | BCRP | multidrug resistance | ABCB1 | P-gp | MRP7 | ABCC10 | ABCG2
Journal Article