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Lipids in health and disease, ISSN 1476-511X, 2019, Volume 18, Issue 1, pp. 2 - 7
Background: ATP-binding cassette (ABC) transporters are involved in a huge range of physiological processes... 
ATP-binding cassette transporters | NUTRITION & DIETETICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | Abcc6 | MOUSE | Pseudoxanthoma elasticum | Mice | MUTATIONS | SECRETION | Gene expression | PCR | Liver - pathology | Kidney - pathology | Lipoproteins - genetics | Adipose Tissue, White - metabolism | Male | ATP Binding Cassette Transporter, Subfamily G, Member 1 - metabolism | ATP-Binding Cassette Transporters - deficiency | Kidney - metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 1 - genetics | ATP-Binding Cassette Transporters - genetics | Biological Transport | ATP Binding Cassette Transporter, Subfamily G, Member 8 - metabolism | Lipoproteins - metabolism | ATP-Binding Cassette Transporters - metabolism | Female | ATP Binding Cassette Transporter, Subfamily B - genetics | ATP Binding Cassette Transporter, Subfamily G, Member 8 - genetics | ATP Binding Cassette Transporter, Subfamily G, Member 5 - metabolism | Disease Models, Animal | ATP Binding Cassette Transporter, Subfamily B, Member 11 - metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 5 - genetics | Adipose Tissue, White - pathology | Pseudoxanthoma Elasticum - metabolism | Liver - metabolism | Gene Expression Regulation | Bile Acids and Salts - metabolism | Pseudoxanthoma Elasticum - pathology | Cholesterol - metabolism | ATP Binding Cassette Transporter, Subfamily B - metabolism | Disease Progression | Mice, Knockout | ATP Binding Cassette Transporter, Subfamily B, Member 11 - genetics | ATP Binding Cassette Transporter, Subfamily D - genetics | Animals | ATP Binding Cassette Transporter, Subfamily D - metabolism | Pseudoxanthoma Elasticum - genetics | Research | Tissues | Adenosine triphosphate | Calcification (ectopic) | Adipose tissue | Disease | Gene regulation | Liver | Homeostasis | Lipids | Phospholipids | ABCA1 protein | Sterols | Metabolites | Mineralization | Rodents | Fibroblasts | Physiology | ABC transporters | Lipid metabolism | Age | Kidneys | Metabolism | Cholesterol | Lipoproteins | Calcification | ATP-binding protein | Mutation | ABC transporter | Bile
Journal Article
Circulation Research, ISSN 0009-7330, 03/2015, Volume 116, Issue 7, pp. 1133 - 1142
.... The ATP binding cassette transporter A1 (ABCA1) facilitates cholesterol efflux to lipid-free apolipoprotein A-I, but the majority of apolipoprotein A-I in the circulation is transported in a lipidated state and ABCA1-dependent efflux to individual... 
foam cells | HDL | ATP-binding cassette transporters | macrophages | cholesterol, HDL | ATP binding cassette transporter 1 | Cholesterol | cholesterol-efflux regulatory protein | ABCA1 | CARDIAC & CARDIOVASCULAR SYSTEMS | APOA-I | HIGH-DENSITY-LIPOPROTEIN | TANGIER DISEASE | EFFLUX | MESSENGER-RNA | CASSETTE TRANSPORTER A1 | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | ABCG1 | APOLIPOPROTEIN-A-I | Lipoproteins - deficiency | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Cricetulus | Humans | Lipoproteins, HDL - metabolism | ATP-Binding Cassette Transporters - physiology | Recombinant Fusion Proteins - metabolism | ATP-Binding Cassette Transporters - deficiency | ATP Binding Cassette Transporter 1 - physiology | Biological Transport | Foam Cells - metabolism | Lipoproteins, HDL2 - metabolism | CHO Cells | Cell Line | Cricetinae | Tangier Disease - enzymology | Tangier Disease - genetics | Cholesterol, HDL - metabolism | Mice, Inbred C57BL | Gene Silencing | Apolipoprotein A-I - metabolism | Cholesterol - metabolism | Lipoproteins - physiology | Mice, Knockout | Particle Size | Macrophages - metabolism | Animals | ATP Binding Cassette Transporter 1 - deficiency | ATP Binding Cassette Transporter 1 - antagonists & inhibitors | Mice | ATP Binding Cassette Transporter 1 - genetics
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 05/2013, Volume 112, Issue 10, pp. 1345 - 1354
RATIONALE:Macrophage accumulation in adipose tissue associates with insulin resistance and increased cardiovascular disease risk. We previously have shown that... 
Apolipoprotein AI | HDL | ABC transporters | Adipocytes | Cholesterol | CARDIAC & CARDIOVASCULAR SYSTEMS | apolipoprotein AI | CELLULAR CHOLESTEROL | DEFICIENT MICE | MACROPHAGE ACCUMULATION | OBESITY | INSULIN-RESISTANCE | ADIPOSE-TISSUE INFLAMMATION | ENDOTHELIAL-CELLS | LIPID RAFTS | TOLL-LIKE RECEPTORS | cholesterol | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | adipocytes | TRANSGENIC MICE | Apolipoprotein A-I - pharmacology | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Reactive Oxygen Species - metabolism | Humans | Lipoproteins, HDL - metabolism | Adipocytes - cytology | Male | Adipocytes - drug effects | Lipoproteins, HDL - pharmacology | Apolipoprotein A-I - genetics | Inflammation - metabolism | Lipoproteins - metabolism | Receptors, LDL - deficiency | ATP-Binding Cassette Transporters - metabolism | ATP Binding Cassette Transporter 1 | Scavenger Receptors, Class B - drug effects | Disease Models, Animal | Receptors, LDL - genetics | Anti-Inflammatory Agents - pharmacology | Mice, Inbred C57BL | RNA, Small Interfering - pharmacology | Cells, Cultured | Receptors, LDL - metabolism | Mice, Transgenic | Apolipoprotein A-I - metabolism | 3T3-L1 Cells | Cholesterol - metabolism | Mice, Knockout | Animals | ATP-Binding Cassette Transporters - drug effects | Membrane Microdomains - drug effects | Adipocytes - metabolism | Biological Transport - physiology | Mice | Lipoproteins - drug effects | Scavenger Receptors, Class B - metabolism | In Vitro Techniques
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2011, Volume 108, Issue 49, pp. 19719 - 19724
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2010, Volume 328, Issue 5986, pp. 1689 - 1693
...; however, how they become increased is poorly understood. Mice deficient in the adenosine triphosphate—binding cassette (ABC... 
Myeloid cells | Leukocytosis | Transgenic animals | HDL lipoproteins | REPORTS | Atherosclerosis | Transgenes | Macrophages | Lesions | Cholesterols | Progenitor cells | CHOLESTEROL | MULTIDISCIPLINARY SCIENCES | MACROPHAGE ABCA1 | LIPID RAFTS | GENE-EXPRESSION | ATHEROSCLEROSIS | MICE | ACCUMULATION | ABCG1 | HIGH-DENSITY-LIPOPROTEIN | APOLIPOPROTEIN-A-I | Cell Proliferation | Lipoproteins - genetics | Lipoproteins, HDL - metabolism | Apolipoprotein A-I - genetics | Leukocytosis - metabolism | ATP-Binding Cassette Transporters - genetics | Atherosclerosis - therapy | Leukocytosis - therapy | Myeloproliferative Disorders - metabolism | Bone Marrow Transplantation | Leukocytosis - physiopathology | Lipoproteins - metabolism | ATP-Binding Cassette Transporters - metabolism | Hematopoietic Stem Cells - physiology | Mice, Inbred DBA | ATP Binding Cassette Transporter 1 | Multipotent Stem Cells - physiology | ATP Binding Cassette Transporter, Subfamily G, Member 1 | Myeloproliferative Disorders - therapy | Signal Transduction | Atherosclerosis - physiopathology | Mice, Inbred C57BL | Cells, Cultured | Mice, Transgenic | Receptors, Interleukin-3 - metabolism | Apolipoprotein A-I - metabolism | Cholesterol - metabolism | Atherosclerosis - metabolism | Macrophages - metabolism | Phenotype | Animals | Myeloid Progenitor Cells - physiology | Myeloproliferative Disorders - physiopathology | Mice | Hypercholesterolemia - metabolism | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Cell proliferation | High density lipoproteins | Physiological aspects | Development and progression | Research | Health aspects | Hematopoietic stem cells | Adenosine triphosphate
Journal Article
The Plant cell, ISSN 1040-4651, 5/2011, Volume 23, Issue 5, pp. 1958 - 1970
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 2014, Volume 34, Issue 2, pp. 279 - 284
... and (2) exert anti-inflammatory effects mediated by transrepression of nuclear factor-κB target genes. We investigated whether myeloid cell deficiency of ATP-binding cassette transporters A1 and G1... 
atherosclerosis | ATP-binding cassette transporters | macrophages | liver X receptor | inflammation | ANTIINFLAMMATORY ACTIVITY | MYELOPROLIFERATIVE DISORDERS | LDL RECEPTOR | TERTIARY-AMINES | ACCELERATES ATHEROSCLEROSIS | KNOCKOUT MICE | NUCLEAR RECEPTOR | REVERSE CHOLESTEROL TRANSPORT | MACROPHAGE ABCA1 | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Lipoproteins - deficiency | Macrophages - transplantation | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Lipoproteins - genetics | Atherosclerosis - genetics | Hydrocarbons, Fluorinated - pharmacology | Male | Aorta - metabolism | Orphan Nuclear Receptors - metabolism | ATP-Binding Cassette Transporters - deficiency | ATP-Binding Cassette Transporters - genetics | Biological Transport | Liver X Receptors | Myocardium - metabolism | Bone Marrow Transplantation | Inflammation Mediators - metabolism | Receptors, LDL - deficiency | Female | Cytokines - genetics | Macrophages - immunology | Disease Models, Animal | Receptors, LDL - genetics | Atherosclerosis - pathology | Atherosclerosis - immunology | Cytokines - metabolism | Anti-Inflammatory Agents - pharmacology | Aorta - drug effects | Mice, Inbred C57BL | Orphan Nuclear Receptors - agonists | Gene Expression Regulation | Myocardium - pathology | Cholesterol - metabolism | Sulfonamides - pharmacology | Atherosclerosis - metabolism | Mice, Knockout | Aorta - pathology | Macrophages - metabolism | Animals | Lipopolysaccharides - pharmacology | ATP Binding Cassette Transporter 1 - deficiency | Benzoates - pharmacology | Macrophages - drug effects | Mice | Benzylamines - pharmacology | Atherosclerosis - prevention & control | ATP Binding Cassette Transporter 1 - genetics
Journal Article
The Plant cell, ISSN 1532-298X, 2007, Volume 19, Issue 1, pp. 131 - 147
Directional transport of the phytohormone auxin is established primarily at the point of cellular efflux and is required for the establishment and maintenance... 
Proteins | Yeasts | Hypocotyls | Plant roots | HeLa cells | Auxins | Cell membranes | Plants | Seedlings | Plant cells | ABC TRANSPORTER | LATERAL ROOT | ROOT GRAVITROPISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | POLAR TRANSPORT | DRUG-RESISTANCE | PLASMA-MEMBRANE | PLANT SCIENCES | CELL BIOLOGY | EFFLUX | GENE-EXPRESSION | TWISTED DWARF1 | RNA-POLYMERASE | Hypocotyl - genetics | ATP Binding Cassette Transporter, Sub-Family B - analysis | Plant Roots - genetics | RNA, Messenger - metabolism | ATP-Binding Cassette Transporters - physiology | Arabidopsis Proteins - metabolism | ATP-Binding Cassette Transporters - genetics | Membrane Transport Proteins - genetics | ATP-Binding Cassette Transporters - metabolism | Membrane Transport Proteins - metabolism | Hypocotyl - metabolism | Arabidopsis Proteins - analysis | Arabidopsis Proteins - genetics | Arabidopsis Proteins - physiology | Plant Roots - metabolism | Indoleacetic Acids - metabolism | Membrane Transport Proteins - analysis | ATP-Binding Cassette Transporters - analysis | Arabidopsis - metabolism | Arabidopsis - genetics | Two-Hybrid System Techniques | ATP Binding Cassette Transporter, Sub-Family B - metabolism | Biological Transport - physiology | Mutation | ATP Binding Cassette Transporter, Sub-Family B - genetics | Plant translocation | Physiological aspects | Glycoproteins | Research | Arabidopsis
Journal Article
Nature (London), ISSN 1476-4687, 2016, Volume 535, Issue 7611, pp. 303 - 307
.... Chow-fed mice lacking T39 (T39(-/-)) display increased high-density lipoprotein cholesterol levels associated with increased enterocyte ATP-binding cassette transporter A1 (Abca1... 
Fatty Liver/genetics | Cholesterol, HDL/metabolism | Atherosclerosis/genetics | Male | Lipoproteins, HDL/deficiency | Ubiquitination | Proteolysis | Diet, High-Fat | Liver X Receptors | Female | Protein Stability | Cholesterol, Dietary/metabolism | Lipogenesis/genetics | Orphan Nuclear Receptors/genetics | Receptors, LDL/deficiency | Gene Expression Regulation | Lipoproteins, LDL/metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 5 | ATP-Binding Cassette Transporters/metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 8 | Sterol Regulatory Element Binding Protein 1/metabolism | Lipoproteins/metabolism | Phosphatidylcholines/biosynthesis | Animals | Hepatocytes/metabolism | Fatty Acids, Unsaturated/metabolism | Ligands | ATP Binding Cassette Transporter 1/metabolism | Mice | Bile Acids and Salts/metabolism | FATTY LIVER-DISEASE | REVERSE CHOLESTEROL TRANSPORT | ER STRESS | MULTIDISCIPLINARY SCIENCES | ELEMENT-BINDING PROTEIN-1C | IN-VIVO | ALPHA | X-RECEPTOR | MICE | OXIDATION-PRODUCTS | INTESTINAL EPITHELIAL-CELLS | Lipoproteins, HDL - genetics | Atherosclerosis - genetics | Cholesterol, Dietary - metabolism | Phosphatidylcholines - biosynthesis | Lipoproteins, HDL - metabolism | Fatty Liver - therapy | Hepatocytes - metabolism | Orphan Nuclear Receptors - metabolism | Phosphatidylcholines - metabolism | ATP Binding Cassette Transporter 1 - metabolism | Atherosclerosis - therapy | Lipogenesis - genetics | Lipoproteins - metabolism | Receptors, LDL - deficiency | ATP-Binding Cassette Transporters - metabolism | Lipoproteins, HDL - deficiency | Lipoproteins, LDL - metabolism | Sterol Regulatory Element Binding Protein 1 - metabolism | Fatty Liver - genetics | Receptors, LDL - genetics | Cholesterol, HDL - metabolism | Fatty Liver - prevention & control | Bile Acids and Salts - metabolism | Fatty Acids, Unsaturated - metabolism | Orphan Nuclear Receptors - genetics | ATP Binding Cassette Transporter, Sub-Family G, Member 8 | Atherosclerosis - prevention & control | ATP Binding Cassette Transporter, Sub-Family G, Member 5 | Proteolipids | Transcription factors | Lipoproteins | Liver diseases | Atherosclerosis | Genetic aspects | Blood lipoproteins | Properties | Ubiquitin-proteasome system | Health aspects | Risk factors | Proteins | Diet | Liver | Gene expression | Cholesterol
Journal Article
Journal Article