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Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 04/2017, Volume 37, Issue 4, pp. 647 - 656
OBJECTIVE—Bempedoic acid (ETC-1002, 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid) is a novel low-density lipoprotein cholesterol–lowering compound. In... 
Lipids | Inflammation | Adenosine triphosphate citrate lyase | Atherosclerosis | atherosclerosis | lipids | ACTIVATED PROTEIN-KINASE | CHOLESTEROL | LOWERING THERAPY | LOW-DENSITY-LIPOPROTEIN | ENDOPLASMIC-RETICULUM STRESS | RECEPTOR-DEFICIENT MICE | adenosine triphosphate citrate lyase | inflammation | STATIN THERAPY | INSULIN-RESISTANCE | ETC-1002 | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | HEPATIC STEATOSIS | Dyslipidemias - genetics | ATP Citrate (pro-S)-Lyase - antagonists & inhibitors | Liver - enzymology | Atherosclerosis - genetics | Male | Dicarboxylic Acids - pharmacology | Insulin - blood | Obesity - blood | Obesity - genetics | Inflammation - blood | Dyslipidemias - enzymology | Atherosclerosis - enzymology | Dyslipidemias - blood | Liver - drug effects | Time Factors | Diet, High-Fat | Lipids - blood | Receptors, LDL - deficiency | Dyslipidemias - prevention & control | ATP Citrate (pro-S)-Lyase - metabolism | Disease Models, Animal | Receptors, LDL - genetics | Genetic Predisposition to Disease | Enzyme Inhibitors - pharmacology | Gene Expression Regulation | Inflammation Mediators - blood | Biomarkers - blood | Mice, Knockout | Atherosclerosis - blood | Blood Glucose - drug effects | Phenotype | Animals | Obesity - prevention & control | Inflammation - genetics | Inflammation - prevention & control | Obesity - enzymology | Blood Glucose - metabolism | Inflammation - enzymology | Atherosclerosis - prevention & control | Fatty Acids - pharmacology
Journal Article
Science, ISSN 0036-8075, 5/2009, Volume 324, Issue 5930, pp. 1076 - 1080
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Cell Reports, ISSN 2211-1247, 10/2016, Volume 17, Issue 4, pp. 1037 - 1052
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Molecular Cell, ISSN 1097-2765, 08/2013, Volume 51, Issue 4, pp. 506 - 518
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Nature Communications, ISSN 2041-1723, 11/2016, Volume 7, Issue 1, p. 13457
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