Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (1350) 1350
au-rich elements (933) 933
humans (892) 892
animals (800) 800
biochemistry & molecular biology (742) 742
rna, messenger - metabolism (642) 642
au-rich element (538) 538
cell biology (471) 471
mice (377) 377
gene-expression (376) 376
rna, messenger - genetics (366) 366
rna-binding proteins - metabolism (353) 353
rna stability (322) 322
base sequence (293) 293
molecular sequence data (293) 293
messenger-rna (278) 278
gene expression (275) 275
protein binding (254) 254
proteins (246) 246
messenger rna (237) 237
gene expression regulation (230) 230
expression (226) 226
3' untranslated regions (225) 225
3'-untranslated region (218) 218
mrna stability (218) 218
rna-binding proteins - genetics (215) 215
tristetraprolin (208) 208
cell line (204) 204
immunology (180) 180
posttranscriptional regulation (178) 178
messenger-rna stability (176) 176
article (170) 170
degradation (170) 170
rna (166) 166
tumor-necrosis-factor (166) 166
tnf-alpha (162) 162
3' untranslated region (159) 159
hur (154) 154
activated protein-kinase (153) 153
stability (152) 152
amino acid sequence (146) 146
rna-binding protein (139) 139
cells, cultured (134) 134
elav proteins (134) 134
3' untranslated regions - genetics (133) 133
hela cells (132) 132
phosphorylation (129) 129
research (129) 129
binding sites (128) 128
binding protein (125) 125
genetics & heredity (125) 125
identification (124) 124
inflammation (122) 122
tristetraprolin - metabolism (121) 121
translation (118) 118
binding-protein (115) 115
cancer (113) 113
elav-like protein 1 (112) 112
protein biosynthesis (108) 108
female (107) 107
rna processing, post-transcriptional (107) 107
transfection (107) 107
binding (106) 106
messenger-rna degradation (105) 105
rna stability - genetics (105) 105
transcription, genetic (105) 105
cells (104) 104
signal transduction (102) 102
analysis (100) 100
binding proteins (100) 100
zinc-finger proteins (100) 100
biophysics (98) 98
in-vivo (97) 97
tristetraprolin - genetics (97) 97
cytoplasm - metabolism (95) 95
deadenylation (95) 95
tumor necrosis factor-alpha - genetics (94) 94
nf-kappa-b (92) 92
ribonucleic acid--rna (92) 92
sequence (92) 92
genetic aspects (91) 91
cell line, tumor (89) 89
physiological aspects (89) 89
in-vitro (88) 88
male (85) 85
rats (85) 85
rna-binding proteins (85) 85
oncology (84) 84
research article (84) 84
saccharomyces-cerevisiae (84) 84
rna, messenger - chemistry (83) 83
genes (82) 82
down-regulation (79) 79
multidisciplinary sciences (79) 79
cytokines (77) 77
decay (75) 75
rna - metabolism (75) 75
biology (74) 74
necrosis-factor-alpha (74) 74
reverse transcriptase polymerase chain reaction (74) 74
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text A HuD‐ZBP1 ribonucleoprotein complex localizes GAP‐43 mRNA into axons through its 3′ untranslated region AU‐rich regulatory element
by Yoo, Soonmoon and Kim, Hak H and Kim, Paul and Donnelly, Christopher J and Kalinski, Ashley L and Vuppalanchi, Deepika and Park, Michael and Lee, Seung J and Merianda, Tanuja T and Perrone‐Bizzozero, Nora I and Twiss, Jeffery L
Journal of Neurochemistry, ISSN 0022-3042, 09/2013, Volume 126, Issue 6, pp. 792 - 804
Localized translation of axonal mRNA s contributes to developmental and regenerative axon growth. Although untranslated regions (UTRs) of many different axonal... 
ZBP1 | GAP‐43 | HuD | RNA‐immunoprecipitation | axon regeneration | mRNA | transport | mRNA transport | RNA-immunoprecipitation | GAP-43 | PHOSPHORYLATION | REGENERATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DORSAL-ROOT GANGLIA | TRANSLATION | NEUROSCIENCES | BINDING PROTEIN HUD | PERIPHERAL-NERVE | BETA-ACTIN SYNTHESIS | GROWTH | NEURONAL CELLS | EXPRESSION | RNA-Binding Proteins - genetics | Immunoprecipitation | Fluorescence Recovery After Photobleaching | 3' Untranslated Regions - genetics | Male | Ganglia, Spinal - cytology | GAP-43 Protein - genetics | RNA, Messenger - metabolism | Actins - genetics | RNA - genetics | Sciatic Nerve - metabolism | Axons - ultrastructure | DNA - biosynthesis | Actins - biosynthesis | GAP-43 Protein - metabolism | RNA, Messenger - genetics | Cells, Cultured | Axons - metabolism | Rats | In Situ Hybridization, Fluorescence | Rats, Sprague-Dawley | DNA - isolation & purification | RNA - biosynthesis | AU Rich Elements - genetics | Animals | Regulatory Elements, Transcriptional | RNA-Binding Proteins - metabolism | Ganglia, Spinal - metabolism | Neurochemistry | Proteins | Brain | Ribonucleic acid--RNA | Neurons | Index Medicus | 3' Untranslated regions
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text The p38/MK2-Driven Exchange between Tristetraprolin and HuR Regulates AU-Rich Element-Dependent Translation
by Tiedje, Christopher and Ronkina, Natalia and Tehrani, Mohammad and Dhamija, Sonam and Laass, Kathrin and Holtmann, Helmut and Kotlyarov, Alexey and Gaestel, Matthias
PLoS Genetics, ISSN 1553-7390, 09/2012, Volume 8, Issue 9, pp. e1002977 - e1002977
TNF expression of macrophages is under stringent translational control that depends on the p38 MAPK/MK2 pathway and the AU-rich element (ARE) in the TNF mRNA.... 
TUMOR-NECROSIS-FACTOR | ACTIVATED PROTEIN-KINASE | 3'-UNTRANSLATED REGION | ALPHA MESSENGER-RNA | MAPKAP KINASES | GENETICS & HEREDITY | BINDING-PROTEIN | ENDOPLASMIC-RETICULUM | BOUND RIBOSOMES | TNF-ALPHA | POSTTRANSLATIONAL MODIFICATION | Tumor Necrosis Factor-alpha - metabolism | Phosphorylation | Protein Biosynthesis | Protein Precursors - genetics | Humans | RNA, Messenger - genetics | Tumor Necrosis Factor-alpha - genetics | ELAV Proteins - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | RNA, Messenger - metabolism | RNA Stability - genetics | Protein Precursors - metabolism | AU Rich Elements - genetics | Macrophages - metabolism | Tristetraprolin - genetics | Tristetraprolin - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Protein-Serine-Threonine Kinases - metabolism | Microbial genetics | Tumor necrosis factor | Physiological aspects | Genetic aspects | Research | Macrophages | Genetic translation | Health aspects | Proteins | Cytokines | Biosynthesis | Kinases | Gene expression | Experiments | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus-induced microRNAs
by McFarland, Adelle P and Horner, Stacy M and Jarret, Abigail and Joslyn, Rochelle C and Bindewald, Eckart and Shapiro, Bruce A and Delker, Don A and Hagedorn, Curt H and Carrington, Mary and Gale, Michael and Savan, Ram
Nature Immunology, ISSN 1529-2908, 01/2014, Volume 15, Issue 1, pp. 72 - 79
IFNL3, which encodes interferon-lambda 3 (IFN-lambda 3), has received considerable attention in the hepatitis C virus (HCV) field, as many independent... 
GENETIC-VARIATION | CLEARANCE | ANTIVIRAL DEFENSES | INTERFERON-LAMBDA | IL28B GENOTYPE | SECONDARY STRUCTURE | INFECTION | IMMUNOLOGY | EXPRESSION | GENOME-WIDE ASSOCIATION | INNATE IMMUNITY | Liver Neoplasms - virology | Liver Neoplasms - genetics | Humans | 3' Untranslated Regions - genetics | Molecular Sequence Data | Genotype | Hepatitis C - genetics | Reverse Transcriptase Polymerase Chain Reaction | RNA Stability - genetics | Sequence Homology, Nucleic Acid | Interleukins - metabolism | Hep G2 Cells | Host-Pathogen Interactions | Interleukins - genetics | AU Rich Elements - genetics | Flow Cytometry | Base Sequence | Hepatitis C - virology | Cell Line, Tumor | Hepacivirus - physiology | Liver Neoplasms - pathology | MicroRNAs - genetics | Polymorphism, Single Nucleotide | Care and treatment | Messenger RNA | Interferon | Genetic aspects | Properties | Hepatitis C | Identification and classification | Genetic polymorphisms | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text A novel mechanism for variable phenotypic expressivity in Mendelian diseases uncovered by an AU-rich element (ARE)-creating mutation
by Patel, Nisha and Khan, Arif O and Al-Saif, Maher and Moghrabi, Walid N and AlMaarik, Balsam M and Ibrahim, Niema and Abdulwahab, Firdous and Hashem, Mais and Alshidi, Tarfa and Alobeid, Eman and Alomar, Rana A and Al-Harbi, Saad and Abouelhoda, Mohamed and Khabar, Khalid S.A and Alkuraya, Fowzan S
Genome Biology, ISSN 1474-7596, 07/2017, Volume 18, Issue 1, pp. 144 - 144
Background: Variable expressivity is a well-known phenomenon in which patients with mutations in one gene display varying degrees of clinical severity,... 
Variable expressivity | AU-rich elements | Cornea | 3'UTR | Tissue-specific | 3 ' UTR | HUMANS | CANCER | DISCOVERY | UTR | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | SEQUENCE | REGIONS | GENETICS & HEREDITY | GENE-EXPRESSION | 3'-UTR | Luciferases - metabolism | Humans | Sodium-Bicarbonate Symporters - genetics | Corneal Dystrophies, Hereditary - genetics | Male | Luciferases - genetics | Corneal Dystrophies, Hereditary - pathology | Base Sequence | Mendelian Randomization Analysis | Adult | Female | Cornea - pathology | 3' Untranslated Regions | Binding Sites | Child | Genes, Reporter | Gene Expression Regulation | Corneal Dystrophies, Hereditary - metabolism | RNA Stability | AU Rich Elements | Sodium-Bicarbonate Symporters - metabolism | Cornea - metabolism | Phenotype | Pedigree | Cell Line, Tumor | Consanguinity | Mutation | Post-transcription | Phenotypes | Disease | mRNA turnover | Families & family life | Genomes | Gene expression | Kinases | Proteins | Genotype & phenotype | Rheumatoid arthritis | MicroRNAs | Fibroblasts | Insulin resistance | Stochasticity | Zinc finger proteins | Cancer | Index Medicus | 3′UTR
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text The Role of Late Sulfide Saturation in the Formation of a Cu- and Au-rich Magma: Insights from the Platinum Group Element Geochemistry of Niuatahi–Motutahi Lavas, Tonga Rear Arc
by Park, Jung-Woo and Campbell, Ian H and Kim, Jonguk and Moon, Jai-Woon
Journal of Petrology, ISSN 0022-3530, 01/2015, Volume 56, Issue 1, pp. 59 - 81
Magmas enriched in Cu and Au are likely to be the most prospective for magmatic-hydrothermal deposits of these metals. However, the mechanism that leads to the... 
Au-rich magma genesis | Magmatic-hydrothermal deposit | Platinum group element | Sulfide saturation | Volatile exsolution | Cu-rich magma genesis | NEW-ZEALAND | ORE | VAPOR TRANSPORT | OXIDATION-STATE | BEHAVIOR | magmatic-hydrothermal deposit | SOLUBILITY | SUBDUCTION-RELATED MAGMAS | SULFUR-CONTENT | GEOCHEMISTRY & GEOPHYSICS | sulfide saturation | MELT INCLUSIONS | volatile exsolution | GREENHILLS COMPLEX | platinum group element | Sulfides | Saturation | Glass | Evolution | Basalt | Compatibility | Copper | Magma
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Tristetraprolin recruits eukaryotic initiation factor 4E2 To repress translation of AU-Rich element-containing mRNAs
by Tao, Xianzun and Gao, Guangxia
Molecular and Cellular Biology, ISSN 0270-7306, 2015, Volume 35, Issue 22, pp. 3921 - 3932
Tristetraprolin (TTP) regulates the expression of AU-rich element-containing mRNAs through promoting the degradation and repressing the translation of target... 
TTP | 4EHP | PROTEIN | INHIBITION | INSTABILITY | DECAY | FAMILY-MEMBERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TNF-ALPHA | BINDING | EIF4E | CELL BIOLOGY | Tumor Necrosis Factor-alpha - metabolism | Up-Regulation | Protein Biosynthesis | Down-Regulation | Humans | RNA, Messenger - genetics | RNA, Messenger - metabolism | AU Rich Elements | Protein Interaction Maps | RNA Cap-Binding Proteins - metabolism | RNA Cap-Binding Proteins - genetics | HEK293 Cells | Tristetraprolin - metabolism | HeLa Cells | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM
by Ripin, Nina and Boudet, Julien and Duszczyk, Malgorzata M and Hinniger, Alexandra and Faller, Michael and Krepl, Miroslav and Gadi, Abhilash and Schneider, Robert J and Sponer, Jirí and Meisner-Kober, Nicole C and Allain, Frédéric H.-T
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2019, Volume 116, Issue 8, pp. 2935 - 2944
Human antigen R (HuR) is a key regulator of cellular mRNAs containing adenylate/uridylate-rich elements (AU-rich elements; AREs). These are a major class of... 
RNA-binding protein | Multiple register | NMR spectroscopy | Dimerization | Crystal structure | STABILITY | MULTIDISCIPLINARY SCIENCES | dimerization | MEDIATE | MOTIF | CANCER | multiple register | MESSENGER-RNA | LIGANDS | STRUCTURAL BASIS | SEQUENCE | crystal structure | DOMAINS | RNA-Binding Proteins - genetics | Magnetic Resonance Spectroscopy | Humans | RNA-Binding Proteins - chemistry | ELAV-Like Protein 1 - genetics | RNA Recognition Motif - genetics | Crystallography, X-Ray | ELAV-Like Protein 1 - chemistry | AU Rich Elements - genetics | Tumor Suppressor Proteins - chemistry | 3' Untranslated Regions | Ribonucleoside Diphosphate Reductase - chemistry | ELAV Proteins - chemistry | HuR protein | Binding | Cell culture | Ribonucleic acids | mRNA | Recognition | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein
by Xu, Nianhua and Shyu, Ann-Bin and Peng, Sheila S.-Y and Chen, Chyi-Ying A
The EMBO Journal, ISSN 0261-4189, 06/1998, Volume 17, Issue 12, pp. 3461 - 3470
An important paradigm for post‐transcriptional regulation is the control of cytoplasmic mRNA stability mediated by AU‐rich elements (AREs) in the 3′... 
nucleocytoplasmic shuttling | AU‐rich element | ELAV protein | HuR | tetracycline‐regulatory system | AU-rich element | Nucleocytoplasmic shuttling | Tetracycline-regulatory system | 3' UNTRANSLATED REGION | DECAY | C-FOS | 1ST STEP | BIOCHEMISTRY & MOLECULAR BIOLOGY | MAMMALIAN-CELLS | CELL BIOLOGY | DEADENYLATION | MESSENGER-RNA | PURIFICATION | DEGRADATION | TRANSCRIPT | tetracycline-regulatory system | ELAV-Like Protein 1 | Genes, fos - physiology | RNA Processing, Post-Transcriptional | Humans | Cytoplasm - metabolism | Ribonucleoproteins - metabolism | RNA, Messenger - metabolism | ELAV Proteins | Genes, jun - physiology | Animals | Cell Nucleus - metabolism | Antigens, Surface | Mice | 3T3 Cells | RNA-Binding Proteins - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Adenosine–uridine-rich element is one of the required cis-elements for epimastigote form stage-specific gene expression of the congolense epimastigote specific protein
by Suganuma, Keisuke and Mochabo, Kennedy Miyoro and Hakimi, Hassan and Yamasaki, Shino and Yamagishi, Junya and Asada, Masahito and Kawazu, Shin-ichiro and Inoue, Noboru
Molecular & Biochemical Parasitology, ISSN 0166-6851, 09/2013, Volume 191, Issue 1, pp. 36 - 43
It is known that gene expression in kinetoplastida is regulated post-transcriptionally. Several previous studies have shown that stage-specific gene expression... 
Epimastigote form | Post-transcriptional regulation | 3′ Untranslated region | Cis-element | RNA binding protein | Trypanosoma congolense | LIFE-CYCLE | TRYPANOSOMA-CONGOLENSE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BRUCEI | IDENTIFICATION | TRANSLATION | TSETSE-FLY | REGION | RNA-BINDING PROTEINS | AU-RICH | PROCYCLIN | 3 ' Untranslated region | PARASITOLOGY | RNA, Protozoan - genetics | Artificial Gene Fusion | Green Fluorescent Proteins - analysis | RNA, Messenger - genetics | Trypanosoma congolense - genetics | Green Fluorescent Proteins - genetics | Trypanosoma congolense - growth & development | Protozoan Proteins - genetics | RNA, Messenger - metabolism | Protozoan Proteins - biosynthesis | RNA, Protozoan - metabolism | DNA Mutational Analysis | Gene Expression Regulation, Developmental | Protein Binding | Electrophoretic Mobility Shift Assay | Organisms, Genetically Modified | 3' Untranslated Regions | Genes, Reporter | RNA-Binding Proteins - metabolism | Genetic research | Gene expression | Adenosine | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text IFN-gamma AU-rich element removal promotes chronic IFN-gamma expression and autoimmunity in mice
by Hodge, Deborah L and Berthet, Cyril and Coppola, Vincenzo and Kastenmüller, Wolfgang and Buschman, Matthew D and Schaughency, Paul M and Shirota, Hidekazu and Scarzello, Anthony J and Subleski, Jeff J and Anver, Miriam R and Ortaldo, John R and Lin, Fanching and Reynolds, Della A and Sanford, Michael E and Kaldis, Philipp and Tessarollo, Lino and Klinman, Dennis M and Young, Howard A
Journal of Autoimmunity, ISSN 0896-8411, 2014, Volume 53, Issue C, pp. 33 - 45
Abstract We generated a mouse model with a 162 nt AU-rich element (ARE) region deletion in the 3′ untranslated region (3′UTR) of the interferon-gamma (IFN-γ)... 
Allergy and Immunology | Autoimmunity | Glomerulonephritis | Systemic lupus erythematosus | Interferon gamma | SYSTEMIC-LUPUS-ERYTHEMATOSUS | SPLENIC MARGINAL ZONE | DENDRITIC CELLS | INNATE | INTERFERON-PRODUCING CELLS | IMMUNOLOGY | HELPER T-CELLS | DISEASE-ACTIVITY | NEPHRITIS | ADAPTIVE IMMUNE-RESPONSES | MURINE B-CELLS | Sequence Deletion | Lupus Nephritis - genetics | Macrophages - pathology | Antibodies, Antinuclear - immunology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Membrane Proteins - genetics | Humans | Interferon Regulatory Factors - genetics | Membrane Proteins - immunology | Lupus Nephritis - immunology | Mice, Knockout | AU Rich Elements - genetics | Interferon Regulatory Factors - immunology | Animals | B-Lymphocytes - immunology | Base Sequence | Interferon-gamma - immunology | Mice | B-Lymphocytes - pathology | Interferon-gamma - genetics | Macrophages - immunology | Interferon | Biological response modifiers | Analysis | Cells | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Chenodeoxycholic acid stabilization of LDL receptor mRNA depends on 3′-untranslated region and AU-rich element-binding protein
by Yashiro, Takuya and Yokoi, Yuka and Shimizu, Makoto and Inoue, Jun and Sato, Ryuichiro
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 2011, Volume 409, Issue 2, pp. 155 - 159
► Chimeric GFP-LDLR 3′-UTR (2.5 kb) mRNA was rapidly degraded. ► The 600-base region of the 3′-UTR is vital for a rapid turnover and the mRNA stabilization by... 
MAPK | Bile acid | AU-rich element | LDL receptor | mRNA stability | MRNA stability | CHOLESTEROL | MECHANISM | STABILITY | SREBP-1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | BERBERINE | DISTINCT | AGENT | BIOPHYSICS | EXPRESSION | DOMAINS | DENSITY-LIPOPROTEIN RECEPTOR | Receptors, LDL - genetics | Humans | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | 3' Untranslated Regions - genetics | RNA Stability - drug effects | RNA, Messenger - metabolism | RNA Stability - genetics | Heterogeneous-Nuclear Ribonucleoprotein D - metabolism | Mitogen-Activated Protein Kinase Kinases - metabolism | Cell Line, Tumor | Chenodeoxycholic Acid - pharmacology | Protein Binding | Enzyme Activation | Messenger RNA | Low density lipoproteins | Protein binding | Deoxycholic acid | Lipoproteins (low density) | 3' Untranslated regions | Lipoprotein (low density) receptors | MAP kinase | Stop codon | mRNA | Chenodiol | lipoprotein receptors | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text 5-Aminoimidazole-4-carboxamide ribonucleoside stabilizes low density lipoprotein receptor mRNA in hepatocytes via ERK-dependent HuR binding to an AU-rich element
by Yashiro, Takuya and Nanmoku, Manami and Shimizu, Makoto and Inoue, Jun and Sato, Ryuichiro
Atherosclerosis, ISSN 0021-9150, 2012, Volume 226, Issue 1, pp. 95 - 101
Abstract Objective 5-Aminoimidazole-4-carboxamide ribonucleoside (AICAR) has pleiotropic and beneficial effects on metabolic disorders. However, the effects of... 
Cardiovascular | AICAR | HuR | ARE | LDL receptor | CELLS | ACTIVATED PROTEIN-KINASE | 3'-UNTRANSLATED REGION | CASCADE | STEROL REGULATORY ELEMENT | FATTY-ACID | LIVER | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | CHOLESTEROL-SYNTHESIS | Receptors, LDL - genetics | AU Rich Elements - physiology | MAP Kinase Signaling System - physiology | Aminoimidazole Carboxamide - analogs & derivatives | Hepatocytes | Humans | RNA, Messenger - physiology | Cells, Cultured | ELAV Proteins - metabolism | Protein Binding | Ribonucleosides - physiology | Low density lipoproteins | Messenger RNA | Atherosclerosis | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Binding of G-quadruplexes to the N-terminal recognition domain of the RNA helicase associated with AU-rich Element (RHAU)
by Meier, Markus and Patel, Trushar R and Booy, Evan P and Marushchak, Oksana and Okun, Natalie and Deo, Soumya and Howard, Ryan and McEleney, Kevin and Harding, Stephen E and Stetefeld, Jörg and McKenna, Sean A
Journal of Biological Chemistry, ISSN 0021-9258, 12/2013, Volume 288, Issue 49, pp. 35014 - 35027
Background: The helicase RHAU requires an N-terminal extension to bind quadruplex structures. Results: This extension adopts an elongated shape and interacts... 
X-ray Scattering | CRYSTAL-STRUCTURE | MAJOR SOURCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | G-quadruplex | TETRAMOLECULAR QUADRUPLEX | RNA-binding Protein | STRANDED GUANINE TETRAPLEX | RHAU | G4R1 | DNA Helicase | RNA Helicase | ANGSTROM RESOLUTION | RESOLVING ACTIVITY | RNA-Protein Interaction | STRUCTURAL BASIS | RESOLUTION STRUCTURE | DNA | DHX36 | METAL-IONS | Humans | Molecular Sequence Data | Substrate Specificity | RNA - genetics | Telomerase - genetics | Base Sequence | Nuclear Magnetic Resonance, Biomolecular | G-Quadruplexes | Telomerase - metabolism | DEAD-box RNA Helicases - metabolism | Nucleic Acid Conformation | Binding Sites | Circular Dichroism | DEAD-box RNA Helicases - chemistry | Peptide Fragments - genetics | RNA - metabolism | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Amino Acid Sequence | Peptide Fragments - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | RNA - chemistry | AU Rich Elements | DEAD-box RNA Helicases - genetics | Peptide Fragments - chemistry | Telomerase - chemistry | Protein Conformation | Index Medicus | RNA
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights