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Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 08/2018, Volume 142, Issue 2, pp. 595 - 604.e16
Autoimmune lymphoproliferative syndrome (ALPS) is a genetic disorder of lymphocyte homeostasis due to impaired apoptosis. It was initially regarded as a very... 
immunodeficiency | RasGRP1 | ALPS-like disease | genetic defect | T-cell receptor signaling | immune dysregulation | IMMUNITY | ACTIVATION | PROTEIN | LYMPHOCYTE | IMMUNOLOGY | CD4 | B-CELL | ALLERGY | GENERATION | T-CELL DEVELOPMENT | Autoimmunity | Cell Proliferation - genetics | Guanine Nucleotide Exchange Factors - genetics | Signal Transduction | Autoimmune Lymphoproliferative Syndrome - diagnosis | Lymphocyte Activation | Humans | Cells, Cultured | Child, Preschool | Male | DNA-Binding Proteins - genetics | Mutation - genetics | Whole Exome Sequencing | Cell Differentiation - genetics | Pedigree | Antibodies, Antinuclear - blood | Autoimmune Lymphoproliferative Syndrome - genetics | Cell Death | Female | Heterozygote | T-Lymphocytes - immunology | Receptors, Antigen, T-Cell - genetics | Infant, Newborn | Siblings | Medical research | Cell death | Analysis | Immunodeficiency | Medicine, Experimental | Genetic research | Genetic aspects | T cells | Cell proliferation | Identification methods | Homeostasis | Intracellular signalling | Activation | Lymphocytes T | Kinases | Gene sequencing | Proteins | T-cell receptor | Signal transduction | Cell activation | Hemolytic anemia | Immunology | Autoimmune hemolytic anemia | Lymphocytes | Genetic analysis | Antinuclear antibodies | Thrombocytopenia | Phenotypes | Immunoglobulins | Autoantibodies | Anemia | Patients | Lymphadenopathy | Mutation | Apoptosis
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 6, pp. 1914 - 1922
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2007, Volume 104, Issue 21, pp. 8953 - 8958
The p21 RAS subfamily of small GTPases, including KRAS, HRAS, and NRAS, regulates cell proliferation, cytoskeletal organization, and other signaling networks,... 
T lymphocytes | Messenger RNA | Cytokines | Lymphocytes | B lymphocytes | Epithelial cells | Small interfering RNA | Immunoblotting | Genetic mutation | Apoptosis | Autoimmunity | B cell lymphoma 2-interacting mediator of cell death | Lymphoma | Lymphoproliferation | Intrinsic apoptosis | IMMUNE-RESPONSE | APOPTOSIS | FACIO-CUTANEOUS SYNDROME | N-RAS | MULTIDISCIPLINARY SCIENCES | lymphoma | BIM | intrinsic apoptosis | NOONAN-SYNDROME | CELL-DEATH | SIGNAL-TRANSDUCTION | autoimmunity | GERMLINE MUTATIONS | GENE-EXPRESSION | lymphoproliferation | Proto-Oncogene Proteins - metabolism | ras Proteins - genetics | Apoptosis - drug effects | Down-Regulation | Humans | Autoimmune Diseases - immunology | Cells, Cultured | ras Proteins - metabolism | Gene Expression Profiling | Lymphoproliferative Disorders - genetics | Lymphoproliferative Disorders - immunology | Extracellular Signal-Regulated MAP Kinases - metabolism | Mutation - genetics | Lymphoproliferative Disorders - pathology | Apoptosis Regulatory Proteins - metabolism | Lymphoproliferative Disorders - metabolism | Autoimmune Diseases - genetics | Proto-Oncogene Proteins c-bcl-2 - metabolism | Bcl-2-Like Protein 11 | RNA Interference | Interleukin-2 - pharmacology | Membrane Proteins - metabolism | Autoimmune Diseases - metabolism | Autoimmune Diseases - pathology | Lymphoproliferative disorders | Research | B cells | Biological Sciences
Journal Article
Journal of Pediatric Hematology/Oncology, ISSN 1077-4114, 07/2018, Volume 40, Issue 5, pp. e305 - e308
We present a case of a 2-year-old female presenting with diffuse lymphadenopathy 2 years following orthotopic heart transplant. Initially, she was diagnosed... 
Fas mutation | posttransplant lymphoproliferative disorder | Kew Words: autoimmune lymphoproliferative syndrome | autoimmune lymphoproliferative syndrome | ONCOLOGY | PEDIATRICS | HEMATOLOGY | FEATURES | Case studies | Care and treatment | Lymphoproliferative disorders | Diagnosis | Autoimmune diseases
Journal Article
Blood, ISSN 0006-4971, 10/2015, Volume 126, Issue 16, pp. 1967 - 1969
Journal Article
Journal Article