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Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 2013, Volume 1831, Issue 1, pp. 42 - 60
Lysophosphatidylcholine (LPC) and lysophosphatidic acid (LPA), the most prominent lysoglycerophospholipids, are emerging as a novel class of inflammatory... 
Autotaxin (ATX, ENPP2) | Lysophosphatidic acid (LPA) | Inflammation | Lysophosphatidylcholine (LPC)
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 2017, Volume 58, Issue 11, pp. 2102 - 2113
Journal Article
FASEB Journal, ISSN 0892-6638, 03/2015, Volume 29, Issue 3, pp. 772 - 785
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 01/2020, Volume 1866, Issue 1, p. 165560
Ocular hypertension due to impaired aqueous humor (AH) drainage through the trabecular meshwork (TM) is a major risk factor for glaucoma, a leading cause of... 
Glaucoma | Trabecular meshwork | Aqueous humor | Autotaxin | Intraocular pressure
Journal Article
Gastroenterology, ISSN 0016-5085, 2010, Volume 139, Issue 3, pp. 1008 - 1018.e1
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2017, Volume 15, Issue 38, pp. 8186 - 8192
Lysophosphatidic acid (LPA) is a chemical mediator with a very simple glycerophospholipid structure. 1-Acyl LPA and 2-acyl LPA are biosynthesized in vivo.... 
LPA RECEPTORS | CHEMISTRY, ORGANIC | PROTEINS | ANALOGS | LYSOPHOSPHOLIPIDS | AUTOTAXIN
Journal Article
Annals of Clinical Biochemistry, ISSN 0004-5632, 7/2018, Volume 55, Issue 4, pp. 469 - 477
Background Because autotaxin reportedly has a better performance than hyaluronic acid as a marker for liver fibrosis for the prediction of cirrhosis caused by... 
type IV collagen | liver fibrosis | lysophosphatidic acid | Autotaxin | hyaluronic acid | RAT-LIVER | CHRONIC HEPATITIS-C | HYALURONATE | LYSOPHOSPHOLIPASE D/AUTOTAXIN | HEPATOCELLULAR-CARCINOMA | PLASMA LYSOPHOSPHATIDIC ACID | SINUSOIDAL ENDOTHELIAL-CELLS | CIRRHOSIS | MEDICAL LABORATORY TECHNOLOGY | RECEPTORS | EXPRESSION
Journal Article
Cancer Research, ISSN 0008-5472, 12/2018, Volume 78, Issue 23, pp. 6607 - 6620
The structure and function of tumor blood vessels profoundly affects the tumor microenvironment. Signals mediated through the lysophosphatidic acid receptor 4... 
ONCOLOGY | BEVACIZUMAB | BLOOD-VESSELS | RHO GTPASES | RECEPTOR | NORMALIZATION | RADIOTHERAPY | NF-KAPPA-B | CELL | AUTOTAXIN | EXPRESSION
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 2014, Volume 55, Issue 7, pp. 1192 - 1214
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 2019, Volume 62, Issue 3, pp. 1373 - 1384
Discovery of potent selective inhibitors targeting a protein from a highly conserved family is challenging. Using a strategy combining structural and... 
TRANSITION | TRPV1 STRUCTURES | ACTIVATION | CHEMISTRY, MEDICINAL | LYSOPHOSPHATIDIC ACID | CELL-MIGRATION | DOCKING | DYNAMICS | MECHANISMS | AUTOTAXIN | EFFICIENT
Journal Article
JOURNAL OF LIPID RESEARCH, ISSN 0022-2275, 07/2014, Volume 55, Issue 7, pp. 1192 - 1214
Journal Article
FUTURE MEDICINAL CHEMISTRY, ISSN 1756-8919, 08/2019, Volume 11, Issue 16, pp. 2063 - 2079
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 03/2018, Volume 148, pp. 397 - 409
Autotaxin (ATX) is a potential target for the treatment of various cancers. A new series of ATX inhibitors was rationally designed and synthesized based on our... 
ATX inhibitors | Pharmacokinetics | Autotaxin | Molecular docking | Cancer |