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Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 5042 - 5042
The etiology of Parkinson's disease (PD) converges on a common pathogenic pathway of mitochondrial defects in which alpha-Synuclein (alpha Syn) is thought to... 
PINK1 | PROTEIN | COMPLEX-I | MEMBRANE | MULTIDISCIPLINARY SCIENCES | DYNAMICS | TAU | AXONAL-TRANSPORT | MICE | TOXICITY | FISSION | Index Medicus
Journal Article
PLoS ONE, 08/2013, Volume 8, Issue 8
When canine adenovirus type 2 (CAdV-2, or also commonly referred to as CAV-2) vectors are injected into the brain parenchyma they preferentially transduce... 
Axonal transport
Journal Article
Neuroscience, ISSN 0306-4522, 10/2017, Volume 362, pp. 104 - 117
The dysregulation of posttranslational modifications of the microtubule-associated protein (MAP) tau plays a key role in Alzheimer’s disease (AD) and related... 
axonal transport | lysosomes | cytoskeleton | mitochondria | degeneration | Index Medicus
Journal Article
01/2016, ISBN 1634836847
Book
Traffic (Copenhagen, Denmark), ISSN 1398-9219, 4/2018, Volume 19, Issue 4, pp. 253 - 262
Increasing evidence has pointed to that dysregulation of the endo-lysosomal system is an early cellular phenotype of pathogenesis for Alzheimer’s disease (AD).... 
Alzheimer’s disease | Rab5 | axonal transport | atrophy | neurodegeneration | endocytosis | axonal dysfunction
Journal Article
CELL, ISSN 0092-8674, 10/2006, Volume 127, Issue 1, pp. 59 - 69
Huntington's disease (HID) is an inherited neurodegenerative disease caused by a glutamine repeat expansion in huntingtin protein. Transcriptional deregulation... 
INDUCED PERMEABILITY TRANSITION | CREB | GLUCOSE-METABOLISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE MODEL | DISEASE | KNOCK-IN MICE | AXONAL-TRANSPORT | ENERGY-METABOLISM | STRIATAL NEURONS | EXPRESSION | CELL BIOLOGY
Journal Article
Cell Reports, ISSN 2211-1247, 12/2018, Volume 25, Issue 13, pp. 3647 - 3660.e2
Abnormalities of the endolysosomal and autophagy systems are found in Alzheimer’s disease, but it is not clear whether defects in these systems are a cause or... 
axonal transport | endosome | autophagy | Alzheimer’s disease | lysosome | live-cell imaging
Journal Article
11/2011
Kinesin-1 transports various cargos along the axon, while the light chain subunits play a role in selecting the types of cargos to transport. However, the... 
Mechanism of Interaction | Axonal Transport | KLC | 0487 | 0419 | Alcadein | JNK-interacting protein (JIP) | Kinesin
Dissertation
Developmental Cell, ISSN 1534-5807, 08/2018, Volume 46, Issue 3, pp. 376 - 387.e7
During development, neurons undergo apoptosis if they do not receive adequate trophic support from tissues they innervate or when detrimental factors activate... 
dynein | sympathetic | HDAC1 | BDNF | axonal transport | P75NTR | p150Glued | neurotrophin | dynactin | NGF | p150 | Index Medicus | Neurotrophin | Axonal Transport | Dynactin | Dynein | Sympathetic
Journal Article
Developmental Biology, ISSN 0012-1606, 07/2019
The cerebellum and the cerebellum-like structure in the mesencephalic tectum in zebrafish contain multiple cell types, including principal cells (i.e.,... 
Journal Article
Neuroscience, ISSN 0306-4522, 06/2019, Volume 409, pp. 152 - 161
Axonopathy manifested by axon swellings might constitute one of the earliest pathological features of Alzheimer's disease. It has been proposed that axonopathy... 
electronic microscope | axonal transport | axonopathy | Aβ plaque pathogenesis | spinal cord | Alzheimer's disease | Analysis | Genetic engineering
Journal Article
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE, ISSN 2157-1422, 07/2012, Volume 2, Issue 7
Tau represents the subunit protein of one of the major hallmarks of Alzheimer disease (AD), the neurofibrillary tangles, and is therefore of major interest as... 
FULL-LENGTH TAU | MEDICINE, RESEARCH & EXPERIMENTAL | IN-VITRO | ALZHEIMER-LIKE FILAMENTS | GLYCOGEN-SYNTHASE KINASE-3 | X-RAY-STRUCTURE | PAIRED HELICAL FILAMENTS | PROLYL ISOMERASE PIN1 | PHOSPHORYLATED TAU | AXONAL-TRANSPORT | MICROTUBULE-ASSOCIATED PROTEIN
Journal Article
Reviews of Modern Physics, ISSN 0034-6861, 01/2013, Volume 85, Issue 1, pp. 135 - 196
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 8/2016, Volume 132, Issue 2, pp. 235 - 256
Alzheimer’s disease (AD) is characterized by amyloid plaques composed of the β-amyloid (Aβ) peptide surrounded by swollen presynaptic dystrophic neurites... 
BACE1 | Pathology | Dystrophic neurite | Neurosciences | Tubulin | Medicine & Public Health | Alzheimer’s disease | 5XFAD mice | Amyloid | Cathepsin D | Microtubule | Axonal transport | Original Paper
Journal Article
Science, ISSN 0036-8075, 09/2017, Volume 357, Issue 6357, p. eaam8526
Journal Article
JOURNAL OF NEUROSCIENCE, ISSN 0270-6474, 11/2011, Volume 31, Issue 44, pp. 15716 - 15726
Mitochondrial shape is determined by fission and fusion reactions, perturbation of which can contribute to neuronal injury and disease. Mitochondrial fission... 
DENDRITIC SPINES | MARIE-TOOTH-DISEASE | EMBRYONIC-DEVELOPMENT | DYNAMIN-RELATED PROTEIN-1 | SYNAPSE FORMATION | AXONAL-TRANSPORT | PROTEIN PHOSPHATASE 2A | FISSION | HIPPOCAMPAL-NEURONS | OXIDATIVE-METABOLISM | NEUROSCIENCES
Journal Article
JOURNAL OF CELL SCIENCE, ISSN 0021-9533, 06/2018, Volume 131, Issue 11, pp. jcs220541 - jcs220541
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers... 
CELL BIOLOGY | Amyloidogenesis | Neurological diseases | Regeneration | Medical centres | Careers | Lysosomes | Axonal transport | Governors | Regeneration (physiology)
Journal Article
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