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Journal Article
Journal of Photochemistry & Photobiology, B: Biology, ISSN 1011-1344, 09/2016, Volume 162, pp. 50 - 55
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 07/2016, Volume 509, Issue 1-2, pp. 499 - 506
Schematic representation of transport of apomorphine and its esters across Caco-2 cell monolayer. Oral delivery of apomorphine via prodrug principle may be a... 
Chylomicron affinity | Stability | Permeability | Caco-2 | Ester prodrug | Apomorphine | MES 2-(N-morpholino)ethanesulfonic acid | LOD Limit of detection | LOQ Limit of quantification | Abbreviations ANOVA analysis of variance | TFA trifluoroacetic acid | DLA dilauroyl apomorphine | LC/MS liquid chromatography-mass spectrometry | DPA dipalmitoyl apomorphine | TIP3P transferable intermolecular potential 3P | H-NMR proton nuclear magnetic resonance | CHARMM chemistry at Harvard Macromolecular Mechanics | HBSS Hank's buffered salt solution | VMD visual molecular dynamics | CM chylomicron | SEM standard error of the mean | TEER trans epithelial electrical resistance | HPLC high performance liquid chromatography | NAMD nanoscale molecular dynamics | HEPES N-[2-hydroxyethyl]piperazine-N′-[2-ethanosulfonate] | MLA monolauroyl apomorphine | Papp apparent permeability | MD molecular dynamics | DRUG | MOLECULAR-DYNAMICS | LYMPHATIC TRANSPORT | RATS | HYDROLYSIS | FATTY-ACIDS | BIOAVAILABILITY | INTESTINAL-ABSORPTION | HALOFANTRINE | PHARMACOLOGY & PHARMACY | GENERAL FORCE-FIELD | Caco-2 Cells | Humans | Chylomicrons - chemistry | Esters - metabolism | Prodrugs - chemistry | Prodrugs - metabolism | Hydrolysis | Chylomicrons - metabolism | Apomorphine - metabolism | Esters - chemistry | Cell Line, Tumor | Apomorphine - chemistry | Intestinal Absorption - physiology | Drugstores | Esters | Pharmacy | Medical research | Analysis | Molecular dynamics | Medicine, Experimental | Mass spectrometry | High performance liquid chromatography
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 08/2016, Volume 190, pp. 33 - 45
Benign prostatic hyperplasia (BPH) is a common urological disorder of men. The ethnomedicinal use of an African plant (Hook.f.) Kalkman ( ) in treating men's... 
Chemical profiling | Benign prostatic hyperplasia | 5α-Reductase | Antioxidant | Anti-inflammatory | Prunus species | LUTS Lower Urinary Tract Symptoms | PI Prostatic index | TI Testicular Index | PCNA Proliferating Cell Nuclear Antigen | Retention factor | 5α-R 5α-Reductase | CITES Convention of International Trade in Endangered Species of Wild Fauna and Flora | GC Gas Chromatography | SOD Superoxide Dismutase | TLC Thin Layer Chromatography | LPO Lipid Peroxidation | MDA Malonaldehyde | PW prostate weight, TW, Testis weight | ANOVA Analysis of Variance | ROS Reacting Oxygen Species | USP United States Pharmacopoeia | UV Ultra Violet | GSH Reduced Glutathione | Abbreviations BPH Benign Prostatic Hyperplasia | DHT Dihydrotestosterone | OXIDATIVE STRESS | CHEMISTRY, MEDICINAL | BARK | SUSCEPTIBILITY | 5 alpha-Reductase | PLANT SCIENCES | BETA-SITOSTEROL | INTEGRATIVE & COMPLEMENTARY MEDICINE | URINARY-TRACT SYMPTOMS | MEN | DOUBLE-BLIND | CREATININE | PHARMACOLOGY & PHARMACY | ANDROGENS | AFRICANA | Urological Agents - pharmacology | Prostatic Hyperplasia - pathology | Triterpenes - pharmacology | Rats, Wistar | Plant Extracts - pharmacology | Sitosterols - pharmacology | Male | Prunus armeniaca - chemistry | Chromatography, Gas | Chromatography, Thin Layer | Prostate - metabolism | Prostate - pathology | Prunus persica - chemistry | Urological Agents - isolation & purification | Inflammation Mediators - metabolism | Prostate - drug effects | Anti-Inflammatory Agents - isolation & purification | Phytotherapy | Disease Models, Animal | Biomarkers - metabolism | Anti-Inflammatory Agents - pharmacology | Prunus domestica - chemistry | Sitosterols - isolation & purification | Plant Extracts - isolation & purification | Prunus dulcis - chemistry | Antioxidants - pharmacology | Plant Bark | Prostatic Hyperplasia - chemically induced | Prostatic Hyperplasia - metabolism | Testosterone | Animals | Antioxidants - isolation & purification | Triterpenes - isolation & purification | Prostatic Hyperplasia - prevention & control | Oxidative Stress - drug effects | Plants, Medicinal | Prostate | Hypertrophy
Journal Article
Translational Research, ISSN 1931-5244, 2015, Volume 166, Issue 6, pp. 509 - 528.e1
A total of 1.7 million traumatic brain injuries (TBIs) occur each year in the United States, but available pharmacologic options for the treatment of acute... 
Internal Medicine | IHC immunohistochemistry | ROS free radical oxygen species | DNPH 2,4-dinitrophenylhydrazine | TBI traumatic brain injury | C control | RB repeat blast | ANOVA analysis of variance | WWE professional wrestler | NFL professional football player | Nox NADPH oxidase | PHF paired helical filament | Std standard | LA lipoic acid | PET positron emission tomography | CTRL control | HO-1 heme oxygenase 1 | mRNA messenger ribonucleic acid | NIH National Institutes of Health | DAB diaminobenzadine | EPM elevated plus maze | NADPH nicotinamide adenine dinucleotide phosphate | SB single blast | Abbreviations CTE chronic traumatic encephalopathy | MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | OXIDATIVE STRESS | RATS | ALPHA-LIPOIC ACID | ENDOPLASMIC-RETICULUM STRESS | ENCEPHALOPATHY | MEDICINE, GENERAL & INTERNAL | NOX FAMILY | PATHWAY | HEME OXYGENASE-1 | MEDICAL LABORATORY TECHNOLOGY | NADPH OXIDASES | Blast Injuries - enzymology | Oxidative Stress | Brain Injuries - enzymology | NADPH Oxidases - metabolism | Blast Injuries - metabolism | Rats | Male | Thioctic Acid - pharmacology | Brain Injuries - metabolism | Rats, Sprague-Dawley | Blast Injuries - pathology | Animals | Brain Injuries - pathology | Apoptosis | Oxidases | Phosphates | Niacinamide | Purines | Cell death | Analysis | Lymphomas | Biochemistry | Superoxide | Explosions | Chronic brain injury | Mental illness | Immunohistochemistry | Medical colleges | RNA | Neurons | Heme
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 09/2015, Volume 86, pp. 16 - 24
Oxidative stress plays a pivotal role in the pathophysiology of diabetic nephropathy, and the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase... 
End-stage renal disease | Oxidative stress | Advanced oxidation protein products | NADPH oxidase | Prospective cohort study | Diabetic nephropathy | Myeloperoxidase | CYBA gene | Genetic association | MAF minor allele frequency | MDRD Modification of Diet in Renal Disease formula | SNP single nucleotide polymorphism | UTR untranslated region | ANOVA analysis of variance | SURGENE Survival Genetic Nephropathy study | ESRD end-stage renal disease | ANCOVA analysis of covariance | CI confidence intervals | AOPP advanced oxidation protein products | ROS reactive oxygen species | Abbreviations ACE angiotensin converting enzyme | UAE urinary albumin excretion | GENEDIAB Génétique de la Néphropathie Diabétique study | HR hazard ratio | NADPH nicotinamide adenine dinucleotide phosphate | MPO myeloperoxidase | eGFR estimated glomerular filtration rate | OR odds ratio | VARIANTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | C242T POLYMORPHISM | RENAL-DISEASE | OXIDATION PROTEIN PRODUCTS | NEPHROPATHY | NAD(P)H OXIDASE | ENDOCRINOLOGY & METABOLISM | CATALASE GENE | P22PHOX | STRESS | Diabetes Mellitus, Type 1 - epidemiology | Promoter Regions, Genetic | Genetic Predisposition to Disease | Prospective Studies | Genetic Association Studies | Oxidative Stress | Gene Frequency | Humans | Middle Aged | Diabetes Mellitus, Type 1 - genetics | Diabetic Nephropathies - genetics | Risk | Diabetes Mellitus, Type 1 - complications | Incidence | Kidney Failure, Chronic - genetics | Young Adult | Kidney Failure, Chronic - epidemiology | NADPH Oxidases - genetics | Adult | Diabetic Nephropathies - epidemiology | Polymorphism, Single Nucleotide | Oxidases | Phosphates | Complications and side effects | Diabetics | Niacinamide | Care and treatment | Chronic kidney failure | Type 1 diabetes | Genes | Diabetic nephropathies | Genetic research | Single nucleotide polymorphisms | Life Sciences | Human health and pathology
Journal Article
Pharmacological Research, ISSN 1043-6618, 03/2016, Volume 105, pp. 152 - 163
Injury to the bronchial epithelium in respiratory diseases such as asthma and COPD results in the loss of barrier function and an elevated sensitivity to... 
Tight junction | Bronchial epithelium | Permeability | Endocannabinoid | Chronic airway inflammation | Anandamide | LLI liquid-liquid interface | ZO zonula occludens | TEER Transepithelial Electrical Resistance | cannabinoid receptor 2 | IBDs inflammatory bowel diseases | ANOVA analysis of variance | HEPES 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid | Abbreviations 2-AG 2-arachidonoylglycerol | COPD chronic obstructive pulmonary disease | receptor cannabinoid receptor 1 | DMSO dimethylsulfoxide | ERK extracellular signal-regulated kinases | ALI air-liquid interface | LTD4 leukotriene D | NAPE N-arachydonoylphosphatidylethanolamine | BALF bronchioalveolar lavage fluid | kDa kilo Dalton (molecular weight unit) | LOX lipooxygenase | DMEM F12 Ham Dulbecco's | COX cyclooxygenase | FAAH fatty acid amide hydrolase | MAPK mitogen-activated protein kinase | EtOH ethanol | PLA2 phospholipase A2 | epithelial volt-ohm-meter version 2 | NDGA nordihydroguaiaretic acid | ATCC American Type Culture Collection | EVOM | IgG immunoglobulin G | PBS phosphate-buffered saline | FBS fetal bovine serum | MEK1/2 MAP/ERK1/2 kinases | TBS-T 0.1% Tween-20 | TNFα tumour necrosis factor-α | MOLECULAR CHARACTERIZATION | RESPONSIVENESS | RECEPTOR | GUINEA-PIGS | PROTEIN-KINASE KINASE | HYPERRESPONSIVENESS | TIGHT JUNCTIONS | INFLAMMATION | ASTHMA | PHARMACOLOGY & PHARMACY | Endocannabinoids - metabolism | Tight Junctions - metabolism | Tumor Necrosis Factor-alpha - metabolism | Cell Line | Epithelial Cells - metabolism | Signal Transduction | Humans | Polyunsaturated Alkamides - metabolism | Occludin - metabolism | Arachidonic Acids - metabolism | Inflammation - metabolism | Bronchi - metabolism | Respiratory Mucosa - metabolism | Zonula Occludens-1 Protein - metabolism | Bronchi - cytology | Unsaturated fatty acids | Metabolites | Arachidonic acid | Proteins | Allergens | COX-2 inhibitors | Analysis | Immunoglobulin G | Gastrointestinal diseases | Protein kinases | Asthma
Journal Article
Journal Article
Ergonomics, ISSN 0014-0139, 08/2019, Volume 62, Issue 8, pp. 995 - 1007
Workplace illumination is known to impact mood, performance and decision-making. Based on the idea that positive feelings associated with light might influence... 
competence | social judgement | warmth | Light | satisfaction with light | APPEARANCE | TASK-PERFORMANCE | BEHAVIOR | PSYCHOLOGY, APPLIED | SELF | MODEL | ERGONOMICS | PSYCHOLOGY | APPRAISAL | IMPACT | MOOD | OFFICE | FACES PREDICT | ENGINEERING, INDUSTRIAL | Evaluation | Laboratories | Decision making | Standardization | Standard error | Design analysis | Variance analysis | Emotions | Confidence intervals | Design | Mood | Lighting | Illumination | Abbreviations | Workplaces
Journal Article