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Journal Article
Colloids and surfaces, B, Biointerfaces, ISSN 0927-7765, 01/2019, Volume 173, pp. 725 - 732
[Display omitted] •A liposomal vector was proposed and optimized by Box Behnken design tool.•siRNA was efficiently complexed with liposome at +5/−1 charge... 
Liposome | siRNA | Ocular keratitis | Box Behnken design | Acanthamoeba | Physical Sciences | Chemistry | Materials Science | Life Sciences & Biomedicine | Technology | Materials Science, Biomaterials | Biophysics | Chemistry, Physical | Science & Technology | RNA, Small Interfering - genetics | Glycogen Phosphorylase - genetics | Rats, Wistar | Acanthamoeba Keratitis - therapy | Cornea - parasitology | Protozoan Proteins - antagonists & inhibitors | Humans | Chlorhexidine - pharmacology | Polyethylene Glycols - chemistry | Protozoan Proteins - genetics | Quaternary Ammonium Compounds - chemistry | Trophozoites - drug effects | Acanthamoeba - pathogenicity | Cornea - drug effects | Protozoan Proteins - metabolism | Trophozoites - enzymology | Acanthamoeba - enzymology | Fatty Acids, Monounsaturated - chemistry | Cornea - pathology | Drug Therapy, Combination | Disease Models, Animal | Phosphoric Monoester Hydrolases - antagonists & inhibitors | Phosphoric Monoester Hydrolases - genetics | Drug Administration Schedule | Acanthamoeba - drug effects | Drug Compounding - methods | Gene Expression Regulation | Rats | Factor Analysis, Statistical | Glycogen Phosphorylase - metabolism | Liposomes - chemistry | Animals | Acanthamoeba Keratitis - parasitology | Liposomes - metabolism | Acanthamoeba Keratitis - pathology | Glycogen Phosphorylase - antagonists & inhibitors | Trophozoites - pathogenicity | Phosphoric Monoester Hydrolases - metabolism | Drug Delivery Systems - methods | Phosphatidylethanolamines - chemistry | RNA, Small Interfering - metabolism | Proteins | Care and treatment | Phosphatases | Keratitis | Synthesis | Proteases | Glycogen | Analysis | Packaging | Index Medicus
Journal Article